In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from RSW to FLO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Fort Myers to Florence, South Carolina as you normally would.

Most accurate provider : When it comes to deals on Fort Myers-Florence, South Carolina flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Fort Myers-Florence, South Carolina flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Fort Myers-Florence, South Carolina flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Fort Myers-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Fort Myers to Florence that include hotel bookings?

Yes. In addition to deals on Fort Myers to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Fort Myers to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Florence.

Can I find deals for business class flights from Fort Myers to Florence?

Yes. Cheapflights offers flight deals from Fort Myers to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$370+ Flights from Fort Myers to Florence, SC

Q: What is the cheapest month to book a flight from Fort Myers to Florence, South Carolina?

Currently, September is the cheapest month in which you can book a flight from Fort Myers to Florence, South Carolina (average of $62). Flying from Fort Myers to Florence, South Carolina in December is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Q: E

Most trusted provider : When it comes to deals on Fort Myers-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Q: Can I find deals for flights from Fort Myers to Florence that include hotel bookings?

Yes. In addition to deals on Fort Myers to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

Q: How can I find direct flights from Fort Myers to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Florence.

Q: Can I find deals for business class flights from Fort Myers to Florence?

Yes. Cheapflights offers flight deals from Fort Myers to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Cheap flight deals from Fort Myers to Florence

One-way

One-way flights from Fort Myers to Florence
Search for one-way flight options from Fort Myers to Florence. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.

Sat 5/236:15 am

RSW

FLO

2 stops17h 42m

American Airlines

Deal found 2/10

$370

Sun 5/247:35 pm

RSW

FLO

1 stop4h 22m

American Airlines

Deal found 2/10

$397

Mon 5/259:58 am

RSW

FLO

1 stop4h 12m

American Airlines

Deal found 2/10

$417

Find flight deals from Fort Myers to Florence

Most accurate provider	Expedia 1 star
Most trusted provider	Expedia 3 stars

Provider with most accurate pricing for Fort Myers SW Florida Intl-Florence flight deals.

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Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Florence flights.

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Use the filters below to find and compare flights from Fort Myers to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersFlorence

RSW - FLO

RSWFLO

Fort Myers SW Florida Intl

Sat 5/23

6:15 am-11:57 pm

2 stops17h 42m

$370

Fort MyersFlorence

RSW - FLO

RSWFLO

Fort Myers SW Florida Intl

Mon 5/25

9:58 am-2:10 pm

1 stop4h 12m

$417

Fort MyersFlorence

RSW - FLO

RSWFLO

Fort Myers SW Florida Intl

Sun 5/24

6:15 am-11:57 pm

2 stops17h 42m

$435

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Most accurate provider: When it comes to deals on Fort Myers-Florence, South Carolina flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Fort Myers-Florence, South Carolina flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Fort Myers-Florence, South Carolina flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Fort Myers-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Fort Myers with our price prediction graph.

RSW-FLO

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Florence

What is the cheapest month to book a flight from Fort Myers to Florence, South Carolina?

Currently, September is the cheapest month in which you can book a flight from Fort Myers to Florence, South Carolina (average of $62). Flying from Fort Myers to Florence, South Carolina in December is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Read reviews from past customers who have flown American Airlines from Fort Myers to Florence. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

11,267 reviews

Reviews

1 / 20

4.0

Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.

American Airlines

7.2

Good

11,267 reviews

American Airlines

7.2

Good

11,267 reviews

Reviews

1 / 20

4.0

Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.

Related info for your journey

Can I find deals for flights from Fort Myers to Florence that include hotel bookings?
Yes. In addition to deals on Fort Myers to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Florence.
Can I find deals for business class flights from Fort Myers to Florence?
Yes. Cheapflights offers flight deals from Fort Myers to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Fort Myers to Florence, South Carolina?
Currently, September is the cheapest month in which you can book a flight from Fort Myers to Florence, South Carolina (average of $62). Flying from Fort Myers to Florence, South Carolina in December is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from Fort Myers to Florence

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$410	Average$472	FlexibilityNo cancel fee	On-time71%

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$370+ Cheap flights from Fort Myers to Florence, SC (RSW - FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to Florence with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Fort Myers to Florence

One-way flights from Fort Myers to FlorenceSearch for one-way flight options from Fort Myers to Florence. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.

Search for one-way flight options from Fort Myers to Florence. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.

Find flight deals from Fort Myers to Florence

Most accurate provider

Most trusted provider

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to Florence that are best for you.

Best time to book a flight from Fort Myers to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Fort Myers with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Florence

What is the cheapest month to book a flight from Fort Myers to Florence, South Carolina?

Reviews of airlines servicing Florence

Read reviews from past customers who have flown American Airlines from Fort Myers to Florence. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Fort Myers to Florence that include hotel bookings?

How can I find direct flights from Fort Myers to Florence?

Can I find deals for business class flights from Fort Myers to Florence?

What is the cheapest month to book a flight from Fort Myers to Florence, South Carolina?

Traveling to a place near Florence?

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Alternative routes for Fort Myers to Florence

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Complete your trip

Complete your trip to Florence by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Fort Myers to Florence by cabin class

Find flights from Fort Myers to Florence, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Other flights to Florence

Explore flights to Florence departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 11, 2026.

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Browse other Fort Myers and Florence flight options. Last updated on February 11, 2026.

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Top airline flying from Fort Myers to Florence

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One-way flights from Fort Myers to Florence
Search for one-way flight options from Fort Myers to Florence. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.