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Florence

$329+ Cheap flights from Colorado to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — FLO
Aug 18 — Aug 251
Tue 8/18
Tue 8/25
1 adult, Economy
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Cheap flight deals from Colorado to Florence

Cheapest flights from Colorado to Florence
Explore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 19, 2026.

This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/43:57 pm
DEN
-
FLO
1 stop5h 40m
American Airlines
Sat 8/83:22 pm
FLO
-
DEN
1 stop5h 57m
American Airlines
Deal found 7/14$329
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:15 am
DEN
-
FLO
1 stop6h 41m
American Airlines
Sat 8/153:22 pm
FLO
-
DEN
1 stop5h 57m
American Airlines
Deal found 7/18$429
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:30 am
DEN
-
FLO
1 stop5h 39m
American Airlines
Fri 10/302:34 pm
FLO
-
DEN
1 stop7h 48m
American Airlines
Deal found 7/15$459
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:20 pm
DEN
-
FLO
1 stop7h 39m
American Airlines
Thu 8/206:22 am
FLO
-
DEN
2 stops12h 31m
American Airlines
Deal found 7/14$469
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:19 pm
DEN
-
FLO
1 stop7h 38m
American Airlines
Thu 10/292:34 pm
FLO
-
DEN
1 stop7h 48m
American Airlines
Deal found 7/15$560
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/93:57 pm
DEN
-
FLO
1 stop6h 01m
American Airlines
Sat 8/156:22 am
FLO
-
DEN
1 stop8h 08m
American Airlines
Deal found 7/18$573
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:41 am
DEN
-
FLO
1 stop5h 29m
American Airlines
Wed 8/53:22 pm
FLO
-
DEN
1 stop5h 57m
American Airlines
Deal found 7/18$574
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:56 pm
DEN
-
FLO
1 stop7h 41m
American Airlines
Wed 8/53:22 pm
FLO
-
DEN
1 stop5h 57m
American Airlines
Deal found 7/18$606
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:46 am
DEN
-
FLO
2 stops15h 11m
American Airlines
Wed 10/282:34 pm
FLO
-
DEN
1 stop7h 48m
American Airlines
Deal found 7/15$626
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:07 pm
COS
-
FLO
2 stops8h 30m
American Airlines
Mon 8/32:35 pm
FLO
-
COS
2 stops9h 48m
American Airlines
Deal found 7/15$704
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:44 am
COS
-
FLO
2 stops10h 53m
American Airlines
Thu 7/232:35 pm
FLO
-
COS
2 stops9h 48m
American Airlines
Deal found 7/18$1,114

Find flight deals from Colorado to Florence

Keep the following information in mind while searching for Colorado to Florence flight deals. Data was last updated July 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$329
(American Airlines)
Provider with most accurate pricing for Denver Intl-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Florence flights.
Search Deals
From Colorado to Florence
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 19, 2026.
Use the filters below to find and compare flights from Colorado to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Thu 8/13

6:15 am-2:56 pm

1 stop6h 41m

Florence

Thu 8/20

3:22 pm-7:19 pm

1 stop5h 57m

$329

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Mon 8/17

6:15 am-2:56 pm

1 stop6h 41m

Florence

Mon 8/24

6:22 am-4:53 pm

2 stops12h 31m

$469

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Tue 8/4

7:16 am-11:37 pm

2 stops14h 21m

Florence

Sat 8/8

3:22 pm-7:19 pm

1 stop5h 57m

$474

Colorado SpringsFlorence

COS - FLO

COSFLO

Colorado Springs

Thu 7/30

1:07 pm-11:37 pm

2 stops8h 30m

Florence

Mon 8/3

2:35 pm-10:23 pm

2 stops9h 48m

$704

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Fri 7/31

6:41 am-2:10 pm

1 stop5h 29m

Florence

Thu 8/6

6:22 am-12:30 pm

1 stop8h 08m

$720

DenverFlorence

DEN - FLO

DENFLO

Denver Intl

Sun 8/2

1:56 pm-11:37 pm

1 stop7h 41m

Florence

Thu 8/6

3:22 pm-7:19 pm

1 stop5h 57m

$1,147

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/14

Sorted by cheapest first

Best time to book a flight from Colorado to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Florence

No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Colorado to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Colorado?

    Most people fly into Florence (FLO) if they book a flight to Florence from Colorado. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Colorado to Florence, South Carolina?

    For as low as $329, American Airlines can have you in Florence, South Carolina from Colorado in 6h 41m. There are 1425 mi between Colorado and Florence, South Carolina.

  • What are the most popular routes from Colorado to Florence, South Carolina?

    The most popular route from Colorado to Florence, South Carolina is Colorado Springs - Florence. You may also consider Montrose County - Florence or Denver Intl - Florence.

  • Can I find deals for flights from Colorado to Florence that include hotel bookings?

    Yes. In addition to deals on Colorado to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Florence.

  • Can I find deals for business class flights from Colorado to Florence?

    Yes. Cheapflights offers flight deals from Colorado to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
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