$339+ Cheap flights from Colorado to Florence, SC (FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — FLO
Sep 18 — Sep 251
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Colorado to Florence
Cheapest
Best
Last-minute
Cheapest flights from Colorado to FlorenceExplore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
Explore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:21 pm -
1 stop7h 37m
Tue 10/66:30 am -
1 stop5h 36m
Deal found 8/14![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:21 pm -
1 stop7h 37m
Wed 9/161:43 pm -
1 stop7h 26m
Deal found 8/15![American Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:14 am -
1 stop5h 04m
Thu 9/176:24 am -
2 stops19h 53m
Deal found 8/15![American Airlines logo]()
$573
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:07 pm -
1 stop5h 50m
Sun 10/185:09 am -
1 stop6h 07m
Deal found 8/16![American Airlines logo]()
$609
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:16 am -
2 stops13h 42m
Fri 9/181:43 pm -
2 stops12h 34m
Deal found 8/17![American Airlines logo]()
$616
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2511:58 am -
2 stops9h 56m
Sat 11/285:09 am -
2 stops9h 45m
Deal found 8/18![American Airlines logo]()
$1,018
Best flights from Colorado to FlorenceDiscover carefully curated flight deals from Colorado to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
Discover carefully curated flight deals from Colorado to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:38 pm -
1 stop5h 20m
Thu 9/176:24 am -
1 stop7h 57m
Deal found 8/15![American Airlines logo]()
$578
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:07 pm -
1 stop5h 50m
Sun 10/185:09 am -
1 stop6h 07m
Deal found 8/17![American Airlines logo]()
$609
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:16 am -
2 stops13h 42m
Fri 9/181:43 pm -
2 stops12h 34m
Deal found 8/17![American Airlines logo]()
$616
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:18 am -
2 stops12h 40m
Wed 9/161:43 pm -
2 stops12h 34m
Deal found 8/15![American Airlines logo]()
$752
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2511:58 am -
2 stops9h 56m
Sat 11/285:09 am -
2 stops9h 45m
Deal found 8/18![American Airlines logo]()
$1,018
Last-minute flights from Colorado to FlorenceDiscover last-minute flight deals from Colorado to Florence. Data last updated August 19, 2026 and is based on user searches.
Discover last-minute flight deals from Colorado to Florence. Data last updated August 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:21 pm -
1 stop7h 37m
Wed 9/161:43 pm -
1 stop7h 26m
Deal found 8/15![American Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:14 am -
1 stop5h 04m
Thu 9/176:24 am -
2 stops19h 53m
Deal found 8/15![American Airlines logo]()
$573
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:23 pm -
1 stop7h 34m
Wed 9/161:43 pm -
1 stop7h 26m
Deal found 8/15![American Airlines logo]()
$1,113
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:16 am -
2 stops13h 42m
Fri 9/181:43 pm -
2 stops12h 34m
Deal found 8/17![American Airlines logo]()
$616
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:21 pm -
1 stop7h 37m
Tue 10/66:30 am -
1 stop5h 36m
Deal found 8/14![American Airlines logo]()
$339
Find flight deals from Colorado to Florence
Keep the following information in mind while searching for Colorado to Florence flight deals. Data was last updated August 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $339 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 19, 2026.
Use the filters below to find and compare flights from Colorado to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverFlorence
DEN Denver Intl - FLO Florence
DENFLO
Denver Intl
Sat 9/12
3:38 pm-10:58 pm
1 stop5h 20m
Florence
Thu 9/17
6:24 am-12:21 pm
1 stop7h 57m
$578
Quickest round-trip
DenverFlorence
DEN Denver Intl - FLO Florence
DENFLO
Denver Intl
Fri 10/9
4:07 pm-11:57 pm
1 stop5h 50m
Florence
Sun 10/18
5:09 am-9:16 am
1 stop6h 07m
$609
DenverFlorence
DEN Denver Intl - FLO Florence
DENFLO
Denver Intl
Mon 9/14
7:16 am-10:58 pm
2 stops13h 42m
Florence
Fri 9/18
1:43 pm-12:17 am
2 stops12h 34m
$616
DenverFlorence
DEN Denver Intl - FLO Florence
DENFLO
Denver Intl
Sat 9/12
8:18 am-10:58 pm
2 stops12h 40m
Florence
Wed 9/16
1:43 pm-12:17 am
2 stops12h 34m
$752
Grand JunctionFlorence
GJT Grand Junction Regnl - FLO Florence
GJTFLO
Grand Junction Regnl
Wed 11/25
11:58 am-11:54 pm
2 stops9h 56m
Florence
Sat 11/28
5:09 am-12:54 pm
2 stops9h 45m
$1,018
Sorted by cheapest first
Best time to book a flight from Colorado to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Colorado with our price prediction graph.
DEN-FLO
GJT-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to Florence
USCO-FLO
DEN-FLO
GJT-FLO
No data available for this route at this time. Please check back soon.
Related info for your journey
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