To save on the cost of your flight from Myrtle Beach to Florence, book at least 32 days before your planned departure. Booking around this time can save you about 65% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $349 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $383.
Flights from Myrtle Beach to Florence lean towards being more expensive in November. Prices are generally better when you fly from Myrtle Beach to Florence in August, with the cheapest ticket starting at $108.