Durham

$81+ Cheap flights from St. Louis (STL) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RDU
Jul 16 — Jul 231
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Durham with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Lambert-St Louis to Durham are usually found in October or January, booked 58 days in advance, depart on a Saturday or Wednesday and return on a Wednesday

Cheap flight deals from St. Louis to Durham

Cheapest flights from St. Louis to Durham
Explore the most affordable flight options available from St. Louis to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:34 pm
STL
-
RDU
1 stop12h 37m
Frontier
Fri 8/712:04 pm
RDU
-
STL
1 stop21h 53m
Frontier
Deal found 6/12$159
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:57 pm
STL
-
RDU
1 stop6h 07m
Frontier
Sun 8/96:14 pm
RDU
-
STL
1 stop15h 43m
Frontier
Deal found 6/11$164
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:57 pm
STL
-
RDU
1 stop6h 07m
Frontier
Sun 7/126:14 pm
RDU
-
STL
1 stop15h 43m
Frontier
Deal found 6/15$167
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:35 am
STL
-
RDU
1 stop12h 42m
Frontier
Sun 9/204:20 pm
RDU
-
STL
1 stop18h 20m
Frontier
Deal found 6/11$186
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:34 pm
STL
-
RDU
1 stop12h 37m
Frontier
Sun 7/196:15 am
RDU
-
STL
1 stop27h 42m
Frontier
Deal found 6/14$190
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:06 pm
STL
-
RDU
1 stop13h 57m
Frontier
Sun 7/56:14 pm
RDU
-
STL
1 stop15h 43m
Frontier
Deal found 6/13$201
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:33 pm
STL
-
RDU
1 stop12h 30m
Frontier
Mon 8/248:06 pm
RDU
-
STL
2 stops22h 24m
Frontier
Deal found 6/14$204
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:33 pm
STL
-
RDU
2 stops21h 36m
Frontier
Tue 9/156:35 am
RDU
-
STL
1 stop28h 05m
Frontier
Deal found 6/15$210
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/134:57 pm
STL
-
RDU
1 stop6h 07m
Frontier
Mon 7/207:32 pm
RDU
-
STL
2 stops23h 05m
Frontier
Deal found 6/15$211
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:57 pm
STL
-
RDU
1 stop6h 07m
Frontier
Mon 8/106:15 am
RDU
-
STL
2 stops33h 41m
Frontier
Deal found 6/11$212
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:34 pm
STL
-
RDU
2 stops19h 35m
Multiple Airlines
Fri 8/712:04 pm
RDU
-
STL
1 stop21h 53m
Multiple Airlines
Deal found 6/12$213
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/14:57 pm
STL
-
RDU
1 stop6h 06m
Multiple Airlines
Mon 8/38:29 pm
RDU
-
STL
1 stop28h 30m
Multiple Airlines
Deal found 6/12$214

Find flight deals from St. Louis to Durham

Keep the following information in mind while searching for St. Louis to Durham flight deals. Data was last updated June 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$159
(Kiwi.com)

One-way from

$81
(Trip.com)

Popular in

May

Cheapest in

October

Average price

$403
Provider with most accurate pricing for Lambert-St Louis-Raleigh-Durham flight deals.
Provider most trusted by Cheapflights users for Lambert-St Louis-Raleigh-Durham flights.
From Lambert-St Louis to Durham
One-way flight from Lambert-St Louis to Durham
Highest demand for flights based on searches. 10% potential increase in price ($48 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Average for round-trip flights in June 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
Use the filters below to find and compare flights from St. Louis to Durham that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Tue 7/21

7:10 pm-10:05 pm

Nonstop1h 55m

Raleigh-Durham

Tue 7/28

6:35 am-7:40 am

Nonstop2h 05m

$297

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 7/8

9:40 am-2:15 pm

1 stop3h 35m

Raleigh-Durham

Sat 7/11

6:15 pm-7:20 pm

Nonstop2h 05m

$313
Quickest round-trip

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sat 9/19

9:00 am-11:50 am

Nonstop1h 50m

Raleigh-Durham

Tue 9/22

6:15 am-7:20 am

Nonstop2h 05m

$316

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Tue 8/18

7:25 am-6:40 pm

2 stops10h 15m

Raleigh-Durham

Wed 8/19

6:00 am-3:38 pm

2 stops10h 38m

$369

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Tue 8/25

8:00 am-2:07 pm

1 stop5h 07m

Raleigh-Durham

Wed 8/26

6:55 am-3:38 pm

2 stops9h 43m

$374

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sat 10/24

6:00 am-11:15 am

1 stop4h 15m

Raleigh-Durham

Sat 10/31

6:25 am-7:30 am

Nonstop2h 05m

$377

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 8/27

6:00 am-2:07 pm

2 stops7h 07m

Raleigh-Durham

Tue 9/15

6:25 am-3:38 pm

2 stops10h 13m

$402

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Fri 7/3

7:55 pm-10:45 pm

Nonstop1h 50m

Raleigh-Durham

Sun 7/5

7:50 pm-8:55 pm

Nonstop2h 05m

$403

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sat 8/15

9:00 am-11:50 am

Nonstop1h 50m

Raleigh-Durham

Sun 8/23

5:20 am-10:40 am

1 stop6h 20m

$412
Cheapest one-way

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Tue 12/8

7:20 am-2:07 pm

1 stop5h 47m

$135

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from St. Louis to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Durham

What is the cheapest time of day to fly from STL to DU8?

Find hourly flight availability from St. Louis to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 16, 2026.

It’s optimal to fly from St. Louis to Durham in the morning. By choosing this option you can save up to 14% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from St. Louis to Durham?

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated June 16, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from St. Louis to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

7.9

Crew

8.6

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

7.9

Crew

8.6

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

7.9

Crew

8.6

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

7.9

Crew

8.6

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

7.9

Crew

8.6

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from St. Louis to Durham?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly out of when you book flights from St. Louis to Durham. 4 airlines have flights from Lambert-St Louis to Durham on a regular basis. Booking flights from Lambert-St Louis to Durham should not be difficult; the airport handles an average of 2 outbound flights to Durham per day.

  • How popular is this St. Louis to Durham flight route?

  • How long is the flight from St. Louis to Durham?

    There are many flights that can get you from St. Louis to Durham in 1h 55m. Fly via Southwest to get the fastest option. The distance from St. Louis to Durham is about 666 mi. Generally, flights for this route are nonstop.

  • What are the cheapest airlines to fly from St. Louis to Durham one-way?

    $62 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $102 and $113, respectively.

  • What are the cheapest flights from St. Louis to Durham?

    Looking for the cheapest flight from St. Louis to Durham? While on average our users pay $356, our data indicates the cheapest price to be $153. The most popular route (Lambert-St Louis - Raleigh-Durham), is priced around $205.

  • Can I find deals for flights from St. Louis to Durham that include hotel bookings?

    Yes. In addition to deals on St. Louis to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Durham.

  • Can I find deals for business class flights from St. Louis to Durham?

    Yes. Cheapflights offers flight deals from St. Louis to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from St. Louis to Durham

Discover the top 4 airlines that operate flights from St. Louis to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$126Average$180FlexibilityNo cancel feeOn-time62%
DeltaCheapest$127Average$373FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$412FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$231Average$444FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.