Durham

$112+ Cheap flights from St. Louis (STL) to Durham, NC

STL — RDU
Dec 13 — Dec 201
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Cheapflights Tip: The best prices from Lambert-St Louis to Durham are usually found in February or January, booked 16 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from St. Louis to Durham

Cheapest flights from St. Louis to Durham

Fri 12/1112:02 pm -
1 stop10h 57m
Mon 12/146:59 am -
1 stop5h 18m
Deal found 11/9$200
Tue 12/86:20 pm -
1 stop22h 30m
Tue 12/1512:00 pm -
1 stop13h 12m
Deal found 11/8$210
Mon 12/712:02 pm -
1 stop22h 24m
Wed 12/96:59 am -
1 stop5h 18m
Deal found 11/9$230
Fri 12/116:20 pm -
1 stop28h 26m
Tue 12/153:46 pm -
1 stop9h 26m
Deal found 11/12$244
Thu 12/36:13 pm -
1 stop22h 34m
Sat 12/512:35 pm -
1 stop12h 37m
Deal found 11/9$259
Thu 12/106:20 pm -
1 stop22h 30m
Sat 12/126:45 pm -
1 stop6h 27m
Deal found 11/9$264
Wed 12/1612:02 pm -
1 stop10h 57m
Wed 1/66:35 am -
2 stops36h 14m
Deal found 11/9$269

Find flight deals from St. Louis to Durham

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$200
(Kiwi.com)

One-way from

$112
(CheapOair)

Popular in

May

Cheapest in

February

Average price

$449
Provider with most accurate pricing for Lambert-St Louis-Raleigh-Durham flight deals.
Provider most trusted by Cheapflights users for Lambert-St Louis-Raleigh-Durham flights.
From Lambert-St Louis to Durham
One-way flight from Lambert-St Louis to Durham
Highest demand for flights based on searches. 8% potential increase in price ($39 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from St. Louis to Durham that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisRaleigh

STL Lambert-St Louis - RDU Raleigh-Durham

STLRDU

Lambert-St Louis

Mon 12/21

6:21 pm-12:06 am

1 stop4h 45m

Raleigh-Durham

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$145

St. LouisRaleigh

STL Lambert-St Louis - RDU Raleigh-Durham

STLRDU

Lambert-St Louis

Thu 12/24

5:58 pm-2:54 pm

1 stop19h 56m

Raleigh-Durham

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$156

St. LouisRaleigh

STL Lambert-St Louis - RDU Raleigh-Durham

STLRDU

Lambert-St Louis

Tue 12/8

6:10 pm-9:00 pm

Nonstop1h 50m

Raleigh-Durham

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$165
Quickest round-trip

St. LouisRaleigh

STL Lambert-St Louis - RDU Raleigh-Durham

STLRDU

Lambert-St Louis

Sat 2/6

8:45 am-11:30 am

Nonstop1h 45m

Raleigh-Durham

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$165

St. LouisRaleigh

STL Lambert-St Louis - RDU Raleigh-Durham

STLRDU

Lambert-St Louis

Mon 12/7

10:15 am-1:05 pm

Nonstop1h 50m

Raleigh-Durham

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$175

St. LouisRaleigh

STL Lambert-St Louis - RDU Raleigh-Durham

STLRDU

Lambert-St Louis

Mon 12/21

7:55 pm-10:50 pm

Nonstop1h 55m

Raleigh-Durham

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$175

St. LouisRaleigh

STL Lambert-St Louis - RDU Raleigh-Durham

STLRDU

Lambert-St Louis

Fri 12/18

7:55 pm-10:50 pm

Nonstop1h 55m

Raleigh-Durham

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$185

St. LouisRaleigh

STL Lambert-St Louis - RDU Raleigh-Durham

STLRDU

Lambert-St Louis

Fri 12/11

8:05 pm-10:55 pm

Nonstop1h 50m

Raleigh-Durham

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$185

St. LouisRaleigh

STL Lambert-St Louis - RDU Raleigh-Durham

STLRDU

Lambert-St Louis

Fri 12/11

5:25 am-2:00 pm

2 stops7h 35m

Raleigh-Durham

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$200

St. LouisRaleigh

STL Lambert-St Louis - RDU Raleigh-Durham

STLRDU

Lambert-St Louis

Thu 12/24

5:05 am-2:27 pm

2 stops8h 22m

Raleigh-Durham

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$240

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/8

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from St. Louis to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from St. Louis with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Durham

What is the cheapest time of day to fly from STL to DU8?

It’s optimal to fly from St. Louis to Durham at noon. By choosing this option you can save up to 16% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from St. Louis to Durham?

Airfare is below average for this route at the moment.
St. Louis to Durham flights typically cost between $311 and $525 in December.
The cheapest round-trip price found within the last 5 days was $200 on Frontier (Dec 11-Dec 14).

Reviews of airlines servicing Durham

See what other customers who have flown with Southwest,American Airlines, andFrontier from St. Louis to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

  • What airport do you fly from for flights from St. Louis to Durham?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly out of when you book flights from St. Louis to Durham. 4 airlines have flights from Lambert-St Louis to Durham on a regular basis. Booking flights from Lambert-St Louis to Durham should not be difficult; the airport handles an average of 1 outbound flight to Durham per day.

  • How popular is this St. Louis to Durham flight route?

  • How long is the flight from St. Louis to Durham?

    There are many flights that can get you from St. Louis to Durham in 1h 50m. Fly via Southwest or Frontier to get the fastest option. The distance from St. Louis to Durham is about 666 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from St. Louis to Durham one-way?

    $62 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $64 and $102, respectively.

  • What are the cheapest flights from St. Louis to Durham?

    Looking for the cheapest flight from St. Louis to Durham? While on average our users pay $407, our data indicates the cheapest price to be $197. The most popular route (Lambert-St Louis - Raleigh-Durham), is priced around $261.

  • Can I find deals for flights from St. Louis to Durham that include hotel bookings?

    Yes. In addition to deals on St. Louis to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Durham.

  • Can I find deals for business class flights from St. Louis to Durham?

    Yes. Cheapflights offers flight deals from St. Louis to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from St. Louis to Durham

AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$126Average$206FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$158Average$433FlexibilityNo cancel feeOn-time71%
DeltaCheapest$246Average$425FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$297Average$467FlexibilityNo cancel feeOn-time63%

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