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Durham

Cheap flights from St. Louis (STL) to Durham, NC

STL — RDU
Oct 22 — Oct 291
Thu 10/22
Thu 10/29
1 adult, Economy
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Cheapflights Tip: The best prices from Lambert-St Louis to Durham are usually found in February or January, booked 16 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Find flight deals from St. Louis to Durham

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Popular in

May

Cheapest in

February

Average price

$467
Provider with most accurate pricing for Lambert-St Louis-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Raleigh-Durham flights.
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Highest demand for flights based on searches. 8% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in September 2026
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Cheapflights Insights

Everything you need to know about your flight from St. Louis to Durham

What is the cheapest time of day to fly from STL to DU8?

It’s optimal to fly from St. Louis to Durham at noon. By choosing this option you can save up to 16% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Durham

See what other customers who have flown with Southwest,American Airlines, andFrontier from St. Louis to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,195 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.
Southwest
8.0
Very good
4,195 reviews
Southwest
8.0
Very good
4,195 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.
American Airlines
7.0
Good
12,082 reviews
Southwest
8.0
Very good
4,195 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.
Frontier
5.6
Fair
2,583 reviews
Southwest
8.0
Very good
4,195 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

  • What airport do you fly from for flights from St. Louis to Durham?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly out of when you book flights from St. Louis to Durham. 4 airlines have flights from Lambert-St Louis to Durham on a regular basis. Booking flights from Lambert-St Louis to Durham should not be difficult; the airport handles an average of 0 outbound flights to Durham per day.

  • How popular is this St. Louis to Durham flight route?

    Within the past month, 8 users have taken a look at flights from Lambert-St Louis to Durham.

  • What are the cheapest airlines to fly from St. Louis to Durham one-way?

    $62 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $64 and $125, respectively.

  • What are the cheapest flights from St. Louis to Durham?

    Looking for the cheapest flight from St. Louis to Durham? While on average our users pay $429, our data indicates the cheapest price to be $148. The most popular route (Lambert-St Louis - Raleigh-Durham), is priced around $274.

  • Can I find deals for flights from St. Louis to Durham that include hotel bookings?

    Yes. In addition to deals on St. Louis to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Durham.

  • Can I find deals for business class flights from St. Louis to Durham?

    Yes. Cheapflights offers flight deals from St. Louis to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from St. Louis to Durham

AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$126Average$219FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$158Average$420FlexibilityNo cancel feeOn-time71%
DeltaCheapest$242Average$401FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$297Average$465FlexibilityNo cancel feeOn-time63%

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