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Durham

$95+ Cheap flights from St. Louis (STL) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/2. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RDU
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheapflights Tip: The best prices from Lambert-St Louis to Durham are usually found in June or April, booked 41 days in advance, depart on a Saturday or Monday and return on a Wednesday

Cheap flight deals from St. Louis to Durham

Keep the following information in mind while searching for St. Louis to Durham flight deals. Data was last updated April 30, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$188
(CheapOair)

One-way from

$100
(American Airlines)

Popular in

March

Cheapest in

June

Average price

$312
Provider with most accurate pricing for Lambert-St Louis-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Raleigh-Durham flights.
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From Lambert-St Louis to Durham
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One-way flight from Lambert-St Louis to Durham
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Highest demand for flights based on searches. 6% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from St. Louis to Durham

Cheapest flights from St. Louis to Durham
Explore the most affordable flight options available from St. Louis to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/95:55 pmSTL - RDU
1 stop19h 04mFrontier
Thu 5/154:25 pmRDU - STL
1 stop8h 41mFrontier
Deal found 4/29$188
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/291:59 pmSTL - RDU
1 stop3h 35mAmerican Airlines
Thu 6/511:12 amRDU - STL
1 stop6h 55mAmerican Airlines
Deal found 4/29$199
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/245:17 pmSTL - RDU
1 stop4h 44mDelta
Sat 5/315:20 pmRDU - STL
1 stop4h 19mDelta
Deal found 4/28$219
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/245:25 pmSTL - RDU
Nonstop1h 50mSouthwest
Tue 5/278:00 amRDU - STL
Nonstop2h 10mSouthwest
Deal found 4/28$293
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/136:12 pmSTL - RDU
1 stop14h 29mSpirit Airlines
Sun 6/154:37 pmRDU - STL
1 stop26h 41mSpirit Airlines
Deal found 4/28$300
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/46:30 amSTL - RDU
2 stops6h 38mUnited Airlines
Sun 6/156:15 amRDU - STL
1 stop5h 30mUnited Airlines
Deal found 4/29$349
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2410:10 amSTL - RDU
2 stops20h 45mMultiple Airlines
Mon 5/2610:17 amRDU - STL
3 stops31h 28mMultiple Airlines
Deal found 4/28$383

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from St. Louis to Durham that are best for you.

Fly from

St. Louis

Fly to

Durham

Route

Depart

Return

Price

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Fri 5/9

5:55 pm-1:59 pm

1 stop19h 04m

Raleigh-Durham

Thu 5/15

4:25 pm-12:06 am

1 stop8h 41m

$188

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 5/29

1:59 pm-6:34 pm

1 stop3h 35m

Raleigh-Durham

Thu 6/5

11:12 am-5:07 pm

1 stop6h 55m

$199

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sat 5/24

5:17 pm-11:01 pm

1 stop4h 44m

Raleigh-Durham

Sat 5/31

5:20 pm-8:39 pm

1 stop4h 19m

$219

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sat 5/24

5:25 pm-8:15 pm

Nonstop1h 50m

Raleigh-Durham

Tue 5/27

8:00 am-9:10 am

Nonstop2h 10m

$293

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Fri 6/13

6:12 pm-9:41 am

1 stop14h 29m

Raleigh-Durham

Sun 6/15

4:37 pm-6:18 pm

1 stop26h 41m

$300

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 6/4

6:30 am-2:08 pm

2 stops6h 38m

Raleigh-Durham

Sun 6/15

6:15 am-10:45 am

1 stop5h 30m

$349

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sat 5/24

10:10 am-7:55 am

2 stops20h 45m

Raleigh-Durham

Mon 5/26

10:17 am-4:45 pm

3 stops31h 28m

$383

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 7/2

4:23 pm-11:58 pm

1 stop6h 35m

$95

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 5/14

5:45 pm-3:35 pm

1 stop20h 50m

$102

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Mon 7/28

1:29 pm-7:10 pm

1 stop4h 41m

$105

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 15 results
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Best time to book a flight from St. Louis to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Durham

How far ahead should I book a flight from St. Louis to Durham?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Durham. Price data was last updated on April 25, 2025.

The best time to book flights from St. Louis to Durham is 41 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from St. Louis to Durham?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Durham (average of $206). Flying from St. Louis to Durham in March is currently the most expensive (average of $294). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to DU8?

Find hourly flight availability from St. Louis to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from St. Louis to Durham as you normally would.

What is the cheapest day to fly from St. Louis to Durham?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Durham. Price data was last updated on November 3, 2024.

Travelers seeking maximum savings on their St. Louis to Durham flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Durham by month

Plan your trip to Durham by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Durham ranges from 2.9 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. April is typically the driest time to visit Durham when rainfall is around 2.9 in.

Temperature in Durham by month

Plan your trip to Durham by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Durham, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated April 30, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from St. Louis to Durham by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Boarding

8.2

Crew

8.6

Entertainment

7.6

Overall

8.0

Food

7.1

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Boarding

8.2

Crew

8.6

Entertainment

7.6

Overall

8.0

Food

7.1

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,929 reviews
Southwest
8.0
Very good
4,295 reviews

Boarding

8.2

Crew

8.6

Entertainment

7.6

Overall

8.0

Food

7.1

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Boarding

8.2

Crew

8.6

Entertainment

7.6

Overall

8.0

Food

7.1

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Boarding

8.2

Crew

8.6

Entertainment

7.6

Overall

8.0

Food

7.1

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Sun Country Air
6.9
Okay
346 reviews
Southwest
8.0
Very good
4,295 reviews

Boarding

8.2

Crew

8.6

Entertainment

7.6

Overall

8.0

Food

7.1

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Durham?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly out of when you book flights from St. Louis to Durham. 5 airlines have flights from Lambert-St Louis to Durham on a regular basis. Booking flights from Lambert-St Louis to Durham should not be difficult; the airport handles an average of 1 outbound flight to Durham per day.

  • How popular is this St. Louis to Durham flight route?

    Within the past month, 3 users have taken a look at flights from Lambert-St Louis to Durham.

  • What are the cheapest airlines to fly from St. Louis to Durham one-way?

    $100 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Frontier and Delta, with prices starting from $102 and $105, respectively.

  • What are the cheapest flights from St. Louis to Durham?

    Looking for the cheapest flight from St. Louis to Durham? While on average our users pay $336, our data indicates the cheapest price to be $146. The most popular route (Lambert-St Louis - Raleigh-Durham), is priced around $255.

  • Can I find deals for flights from St. Louis to Durham that include hotel bookings?

    Yes. In addition to deals on St. Louis to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Durham.

  • Can I find deals for business class flights from St. Louis to Durham?

    Yes. Cheapflights offers flight deals from St. Louis to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Durham?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Durham (average of $206). Flying from St. Louis to Durham in March is currently the most expensive (average of $294). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from St. Louis to Durham

Discover the top 5 airlines that operate flights from St. Louis to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$164FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$218Average$370FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$366FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$249Average$366FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$325Average$427FlexibilityNo cancel feeOn-time69%

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