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Durham

$57+ Cheap flights from St. Louis (STL) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RDU
Jan 9 — Jan 161
Fri 1/9
Fri 1/16
1 adult, Economy
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Cheapflights Tip: The best prices from Lambert-St Louis to Durham are usually found in October or September, booked 58 days in advance, depart on a Monday or Wednesday and return on a Wednesday

Cheap flight deals from St. Louis to Durham

Cheapest flights from St. Louis to Durham
Explore the most affordable flight options available from St. Louis to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 10, 2025.

This Frontier deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/199:07 amSTL - RDU
1 stop5h 29mFrontier
Sun 1/49:05 pmRDU - STL
1 stop12h 07mFrontier
Deal found 12/9$188
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/143:30 pmSTL - RDU
1 stop16h 37mMultiple Airlines
Wed 12/178:15 amRDU - STL
1 stop26h 25mMultiple Airlines
Deal found 12/7$209
This Booking.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:43 pmSTL - RDU
1 stop21h 58mFrontier
Sun 12/286:00 amRDU - STL
1 stop4h 40mFrontier
Deal found 12/7$219
This Mytrip deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:27 pmSTL - RDU
1 stop25h 01mFrontier
Tue 12/306:00 amRDU - STL
1 stop4h 40mFrontier
Deal found 12/9$222
This Booking.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:30 pmSTL - RDU
1 stop24h 14mFrontier
Tue 12/168:14 pmRDU - STL
1 stop27h 19mFrontier
Deal found 12/8$225
This Booking.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:27 pmSTL - RDU
1 stop15h 01mFrontier
Sun 1/49:05 pmRDU - STL
1 stop12h 07mFrontier
Deal found 12/8$226
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2310:48 amSTL - RDU
1 stop12h 25mFrontier
Fri 1/236:10 amRDU - STL
1 stop25h 41mFrontier
Deal found 12/8$229
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:42 amSTL - RDU
1 stop12h 31mMultiple Airlines
Tue 12/236:14 pmRDU - STL
2 stops40h 26mMultiple Airlines
Deal found 12/8$245
This Booking.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/184:27 pmSTL - RDU
1 stop17h 25mFrontier
Tue 12/238:14 pmRDU - STL
1 stop27h 19mFrontier
Deal found 12/8$251
This Frontier deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/159:54 amSTL - RDU
1 stop5h 50mFrontier
Thu 12/186:00 amRDU - STL
1 stop4h 40mFrontier
Deal found 12/8$267

Find flight deals from St. Louis to Durham

Keep the following information in mind while searching for St. Louis to Durham flight deals. Data was last updated December 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$171
(Kiwi.com)

One-way from

$57
(Kiwi.com)

Popular in

August

Cheapest in

October

Average price

$375
Provider with most accurate pricing for Lambert-St Louis-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Raleigh-Durham flights.
Search Deals
From Lambert-St Louis to Durham
Search Deals
One-way flight from Lambert-St Louis to Durham
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
Use the filters below to find and compare flights from St. Louis to Durham that are best for you.

Fly from

St. Louis

Fly to

Durham

Route

Depart

Return

Price

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Fri 1/9

3:43 pm-12:12 am

1 stop7h 29m

Raleigh-Durham

Mon 1/12

8:14 pm-6:51 am

2 stops35h 37m

$173

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 2/19

10:42 am-12:12 am

1 stop12h 30m

Raleigh-Durham

Mon 2/23

7:50 pm-10:02 am

2 stops39h 12m

$202

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 12/31

4:27 pm-8:28 am

1 stop15h 01m

Raleigh-Durham

Mon 1/5

8:14 pm-10:33 pm

1 stop27h 19m

$219

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 12/24

4:27 pm-6:28 pm

1 stop25h 01m

Raleigh-Durham

Tue 12/30

6:00 am-9:40 am

1 stop4h 40m

$222

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 3/5

5:11 pm-4:44 pm

1 stop22h 33m

Raleigh-Durham

Fri 3/6

8:46 pm-7:13 am

1 stop11h 27m

$230

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Fri 2/20

7:43 pm-9:51 am

2 stops13h 08m

Raleigh-Durham

Mon 2/23

8:48 am-10:33 pm

1 stop14h 45m

$232

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 2/19

3:49 pm-8:12 am

1 stop15h 23m

Raleigh-Durham

Sun 2/22

10:59 pm-11:59 pm

1 stop26h 00m

$250

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Tue 12/23

10:48 am-12:13 am

1 stop12h 25m

Raleigh-Durham

Fri 1/23

4:07 pm-6:51 am

2 stops15h 44m

$261

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 3/12

10:42 am-7:53 am

2 stops20h 11m

Raleigh-Durham

Sun 3/15

8:46 pm-7:13 am

1 stop11h 27m

$339

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 1/8

8:15 am-11:05 am

Nonstop1h 50m

Raleigh-Durham

Mon 1/19

6:40 pm-8:00 pm

Nonstop2h 20m

$341

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/8

Showing 1-10 of 18 results
1
2

Best time to book a flight from St. Louis to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Durham

How far ahead should I book a flight from St. Louis to Durham?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Durham. Price data was last updated on December 5, 2025.

The best time to book flights from St. Louis to Durham is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from St. Louis to Durham?

Currently, October is the cheapest month in which you can book a flight from St. Louis to Durham (average of $144). Flying from St. Louis to Durham in February is currently the most expensive (average of $250). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to DU8?

Find hourly flight availability from St. Louis to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 10, 2025.

It’s optimal to fly from St. Louis to Durham in the evening. By choosing this option you can save up to 39% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from St. Louis to Durham?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Durham. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their St. Louis to Durham flight should consider departing on Monday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated December 10, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from St. Louis to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,252 reviews

Food

7.0

Boarding

8.1

Overall

7.9

Comfort

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,252 reviews
Southwest
7.9
Good
4,252 reviews

Food

7.0

Boarding

8.1

Overall

7.9

Comfort

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,007 reviews
Southwest
7.9
Good
4,252 reviews

Food

7.0

Boarding

8.1

Overall

7.9

Comfort

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,047 reviews
Southwest
7.9
Good
4,252 reviews

Food

7.0

Boarding

8.1

Overall

7.9

Comfort

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.8
Fair
3,085 reviews
Southwest
7.9
Good
4,252 reviews

Food

7.0

Boarding

8.1

Overall

7.9

Comfort

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Durham?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly out of when you book flights from St. Louis to Durham. 4 airlines have flights from Lambert-St Louis to Durham on a regular basis. Booking flights from Lambert-St Louis to Durham should not be difficult; the airport handles an average of 1 outbound flight to Durham per day.

  • How popular is this St. Louis to Durham flight route?

    Within the past month, 4 users have taken a look at flights from Lambert-St Louis to Durham.

  • How long is the flight from St. Louis to Durham?

    There are many flights that can get you from St. Louis to Durham in 7h 29m. Fly via Frontier to get the fastest option. The distance from St. Louis to Durham is about 666 mi.

  • What are the cheapest airlines to fly from St. Louis to Durham one-way?

    $72 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and Southwest, with prices starting from $113 and $127, respectively.

  • What are the cheapest flights from St. Louis to Durham?

    Looking for the cheapest flight from St. Louis to Durham? While on average our users pay $454, our data indicates the cheapest price to be $213. The most popular route (Lambert-St Louis - Raleigh-Durham), is priced around $240.

  • Can I find deals for flights from St. Louis to Durham that include hotel bookings?

    Yes. In addition to deals on St. Louis to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Durham.

  • Can I find deals for business class flights from St. Louis to Durham?

    Yes. Cheapflights offers flight deals from St. Louis to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Durham?

    Currently, October is the cheapest month in which you can book a flight from St. Louis to Durham (average of $144). Flying from St. Louis to Durham in February is currently the most expensive (average of $250). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from St. Louis to Durham

Discover the top 4 airlines that operate flights from St. Louis to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$128Average$189FlexibilityNo cancel feeOn-time62%
DeltaCheapest$158Average$381FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$375FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$257Average$390FlexibilityNo cancel feeOn-time63%

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