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Durham

$73+ Cheap flights from St. Louis (STL) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RDU
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheapflights Tip: The best prices from Lambert-St Louis to Durham are usually found in August or October, booked 36 days in advance, depart on a Monday or Wednesday and return on a Wednesday

Cheap flight deals from St. Louis to Durham

Keep the following information in mind while searching for St. Louis to Durham flight deals. Data was last updated August 20, 2025.

Round-trip from

$160
(FlightHub)

One-way from

$73
(Priceline)

Popular in

June

Cheapest in

August

Average price

$334
From Lambert-St Louis to Durham
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One-way flight from Lambert-St Louis to Durham
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from St. Louis to Durham

Cheapest flights from St. Louis to Durham
Explore the most affordable flight options available from St. Louis to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/191:57 pmSTL - RDU
1 stop18h 56mFrontier
Mon 9/226:22 amRDU - STL
1 stop9h 42mFrontier
Deal found 8/18$160
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/410:49 amSTL - RDU
1 stop22h 14mFrontier
Mon 9/86:22 amRDU - STL
1 stop9h 42mFrontier
Deal found 8/18$163
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/114:00 pmSTL - RDU
1 stop5h 50mFrontier
Sun 9/146:22 amRDU - STL
1 stop9h 42mFrontier
Deal found 8/19$165
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:07 amSTL - RDU
1 stop5h 55mFrontier
Sun 11/166:10 amRDU - STL
1 stop5h 02mFrontier
Deal found 8/19$175
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/254:00 pmSTL - RDU
1 stop5h 50mFrontier
Sun 9/286:38 pmRDU - STL
1 stop21h 26mFrontier
Deal found 8/18$176
This Frontier deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/44:00 pmSTL - RDU
1 stop5h 50mFrontier
Sun 9/79:55 pmRDU - STL
2 stops18h 09mFrontier
Deal found 8/17$186
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/191:57 pmSTL - RDU
1 stop18h 56mFrontier
Sat 9/2710:48 amRDU - STL
1 stop27h 19mFrontier
Deal found 8/18$194
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/224:00 pmSTL - RDU
1 stop5h 58mFrontier
Sat 9/277:03 pmRDU - STL
1 stop19h 04mFrontier
Deal found 8/18$198
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:55 pmSTL - RDU
1 stop19h 43mFrontier
Sat 9/277:03 pmRDU - STL
1 stop19h 04mFrontier
Deal found 8/19$205
This Priceline deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/233:02 pmSTL - RDU
1 stop6h 36mFrontier
Mon 8/256:10 amRDU - STL
1 stop7h 46mFrontier
Deal found 8/19$208

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from St. Louis to Durham that are best for you.

Fly from

St. Louis

Fly to

Durham

Route

Depart

Return

Price

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 9/18

4:00 pm-10:50 pm

1 stop5h 50m

Raleigh-Durham

Sun 9/21

9:02 pm-1:02 pm

1 stop17h 00m

$160

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Fri 9/19

1:57 pm-6:08 pm

1 stop27h 11m

Raleigh-Durham

Mon 9/22

6:22 am-3:04 pm

1 stop9h 42m

$160

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 9/4

4:00 pm-5:38 pm

1 stop24h 38m

Raleigh-Durham

Sun 9/7

9:02 pm-1:02 pm

1 stop17h 00m

$160

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sun 9/28

10:39 am-10:03 am

1 stop22h 24m

Raleigh-Durham

Wed 10/15

12:30 pm-10:37 am

1 stop23h 07m

$163

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 9/4

10:49 am-10:03 am

1 stop22h 14m

Raleigh-Durham

Mon 9/8

6:22 am-3:04 pm

1 stop9h 42m

$163

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sun 10/19

11:32 am-10:59 pm

1 stop10h 27m

Raleigh-Durham

Fri 10/24

6:15 am-10:37 am

1 stop5h 22m

$163

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 9/25

10:49 am-10:03 am

1 stop22h 14m

Raleigh-Durham

Sun 9/28

6:38 pm-3:04 pm

1 stop21h 26m

$163

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sun 9/14

10:39 am-10:03 am

1 stop22h 24m

Raleigh-Durham

Sun 9/21

6:38 pm-3:04 pm

1 stop21h 26m

$163

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 9/11

4:00 pm-10:50 pm

1 stop5h 50m

Raleigh-Durham

Sun 9/14

6:22 am-3:04 pm

1 stop9h 42m

$165

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 11/13

11:07 am-6:02 pm

1 stop5h 55m

Raleigh-Durham

Sun 11/16

6:10 am-10:12 am

1 stop5h 02m

$175

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 19 results
1
2

Best time to book a flight from St. Louis to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Durham

How far ahead should I book a flight from St. Louis to Durham?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Durham. Price data was last updated on August 8, 2025.

The best time to book flights from St. Louis to Durham is 36 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from St. Louis to Durham?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Durham (average of $206). Flying from St. Louis to Durham in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to DU8?

Find hourly flight availability from St. Louis to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from St. Louis to Durham as you normally would.

What is the cheapest day to fly from St. Louis to Durham?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Durham. Price data was last updated on November 3, 2024.

Travelers seeking maximum savings on their St. Louis to Durham flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated August 20, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from St. Louis to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,982 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Frontier
5.8
Fair
3,207 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Durham?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly out of when you book flights from St. Louis to Durham. 4 airlines have flights from Lambert-St Louis to Durham on a regular basis. Booking flights from Lambert-St Louis to Durham should not be difficult; the airport handles an average of 1 outbound flight to Durham per day.

  • How popular is this St. Louis to Durham flight route?

    Within the past month, 4 users have taken a look at flights from Lambert-St Louis to Durham.

  • How long is the flight from St. Louis to Durham?

    There are many flights that can get you from St. Louis to Durham in 5h 50m. Fly via Frontier to get the fastest option. The distance from St. Louis to Durham is about 666 mi.

  • What are the cheapest flights from St. Louis to Durham?

    Looking for the cheapest flight from St. Louis to Durham? While on average our users pay $318, our data indicates the cheapest price to be $108. The most popular route (Lambert-St Louis - Raleigh-Durham), is priced around $186.

  • Can I find deals for flights from St. Louis to Durham that include hotel bookings?

    Yes. In addition to deals on St. Louis to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Durham.

  • Can I find deals for business class flights from St. Louis to Durham?

    Yes. Cheapflights offers flight deals from St. Louis to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Durham?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Durham (average of $206). Flying from St. Louis to Durham in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 4 airlines flying from St. Louis to Durham

Discover the top 4 airlines that operate flights from St. Louis to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$116Average$218FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$223Average$368FlexibilityNo cancel feeOn-time63%
DeltaCheapest$229Average$365FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$246Average$382FlexibilityNo cancel feeOn-time71%

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