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Durham

$93+ Cheap flights from Des Moines (DSM) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RDU
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Durham are usually found in May or September, booked 30 days in advance, depart on a Wednesday or Tuesday and return on a Friday

Cheap flight deals from Des Moines to Durham

Keep the following information in mind while searching for Des Moines to Durham flight deals. Data was last updated August 18, 2025.

Round-trip from

$207
(Kiwi.com)

One-way from

$93
(FlightHub)

Popular in

December

Cheapest in

May

Average price

$359
From Des Moines to Durham
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One-way flight from Des Moines to Durham
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Highest demand for flights based on searches. 5% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Des Moines to Durham

Cheapest flights from Des Moines to Durham
Explore the most affordable flight options available from Des Moines to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/158:25 amDSM - RDU
1 stop9h 39mMultiple Airlines
Thu 9/189:49 pmRDU - DSM
1 stop17h 51mMultiple Airlines
Deal found 8/17$207
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1710:14 amDSM - RDU
1 stop22h 39mMultiple Airlines
Thu 9/189:49 pmRDU - DSM
1 stop17h 51mMultiple Airlines
Deal found 8/17$228
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:41 amDSM - RDU
1 stop26h 54mMultiple Airlines
Thu 10/99:39 pmRDU - DSM
1 stop18h 11mMultiple Airlines
Deal found 8/18$237
This Frontier deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/122:25 pmDSM - RDU
2 stops18h 28mFrontier
Sun 9/149:55 pmRDU - DSM
2 stops16h 45mFrontier
Deal found 8/16$238
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/158:25 amDSM - RDU
1 stop9h 39mMultiple Airlines
Tue 9/2311:03 amRDU - DSM
2 stops23h 21mMultiple Airlines
Deal found 8/17$240
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:41 amDSM - RDU
1 stop26h 54mMultiple Airlines
Fri 10/101:59 pmRDU - DSM
1 stop19h 30mMultiple Airlines
Deal found 8/16$248
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:41 amDSM - RDU
1 stop26h 54mMultiple Airlines
Wed 10/86:30 amRDU - DSM
1 stop16h 15mMultiple Airlines
Deal found 8/16$251
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:51 amDSM - RDU
1 stop26h 29mMultiple Airlines
Fri 10/171:59 pmRDU - DSM
1 stop19h 30mMultiple Airlines
Deal found 8/16$255

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Des Moines to Durham that are best for you.

Fly from

Des Moines

Fly to

Durham

Route

Depart

Return

Price

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Mon 9/15

8:25 am-7:04 pm

1 stop9h 39m

Raleigh-Durham

Thu 9/18

9:49 pm-2:40 pm

1 stop17h 51m

$207

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Wed 9/17

10:14 am-9:53 am

1 stop22h 39m

Raleigh-Durham

Thu 9/18

9:49 pm-2:40 pm

1 stop17h 51m

$228

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Thu 10/2

10:41 am-2:35 pm

1 stop26h 54m

Raleigh-Durham

Thu 10/9

9:39 pm-2:50 pm

1 stop18h 11m

$237

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Fri 9/12

2:25 pm-9:53 am

2 stops18h 28m

Raleigh-Durham

Sun 9/14

9:55 pm-1:40 pm

2 stops16h 45m

$238

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Mon 9/15

8:25 am-7:04 pm

1 stop9h 39m

Raleigh-Durham

Tue 9/23

11:03 am-9:24 am

2 stops23h 21m

$240

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Thu 10/2

10:41 am-2:35 pm

1 stop26h 54m

Raleigh-Durham

Fri 10/10

1:59 pm-8:29 am

1 stop19h 30m

$248

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Thu 10/2

10:41 am-2:35 pm

1 stop26h 54m

Raleigh-Durham

Wed 10/8

6:30 am-9:45 pm

1 stop16h 15m

$251

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Sun 11/9

2:32 pm-4:36 pm

1 stop25h 04m

$93

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Thu 9/11

2:25 pm-4:28 pm

1 stop25h 03m

$93

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Thu 10/30

2:32 pm-4:36 pm

1 stop25h 04m

$93

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Showing 1-10 of 15 results
1
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Best time to book a flight from Des Moines to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Durham

How far ahead should I book a flight from Des Moines to Durham?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Durham. Price data was last updated on August 8, 2025.

Booking 30 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Durham. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Des Moines to Durham?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Durham (average of $206). Flying from Des Moines to Durham in March is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to DU8?

Find hourly flight availability from Des Moines to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Durham as you normally would.

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated August 18, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Des Moines to Durham by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,925 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Durham?

    For a flight from Des Moines to Durham, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city. Des Moines is the only Des Moines airport and it handles 0 outbound flights to Durham per day. 4 airlines have flights to Durham from Des Moines on a regular basis.

  • How long is the flight from Des Moines to Durham?

    Departing from Des Moines to Durham will take you 18h 28m. The distance between Des Moines and Durham is about 890 mi.

  • Can I find deals for flights from Des Moines to Durham that include hotel bookings?

    Yes. In addition to deals on Des Moines to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Durham.

  • Can I find deals for business class flights from Des Moines to Durham?

    Yes. Cheapflights offers flight deals from Des Moines to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Durham?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Durham (average of $206). Flying from Des Moines to Durham in March is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Des Moines to Durham

Discover the top 4 airlines that operate flights from Des Moines to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$238Average$329FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$322FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$276Average$391FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$296Average$429FlexibilityNo cancel feeOn-time63%

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