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Des Moines

$195+ Cheap flights from Spartanburg, SC to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — DSM
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheapflights Tip: The best prices from Spartanburg to Des Moines are usually found in March or September, booked 43 days in advance, depart on a Tuesday or Thursday and return on a Tuesday

Cheap flight deals from Spartanburg to Des Moines

Keep the following information in mind while searching for Spartanburg to Des Moines flight deals. Data was last updated April 30, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$279
(Mytrip)

One-way from

$195
(Southwest)

Popular in

December

Cheapest in

March

Average price

$447
Provider with most accurate pricing for Charlotte Douglas-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Charlotte Douglas-Des Moines flights.
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From Spartanburg to Des Moines
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One-way flight from Spartanburg to Des Moines
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Spartanburg to Des Moines

Cheapest flights from Spartanburg to Des Moines
Explore the most affordable flight options available from Spartanburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2611:28 amCLT - DSM
2 stops31h 43mMultiple Airlines
Sun 6/296:32 pmDSM - CLT
1 stop21h 05mMultiple Airlines
Deal found 4/29$279
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/75:30 amCLT - DSM
1 stop5h 44mDelta
Mon 9/82:14 pmDSM - CLT
1 stop7h 06mDelta
Deal found 4/29$341
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/283:40 pmCLT - DSM
1 stop7h 25mSouthwest
Fri 5/307:00 amDSM - CLT
1 stop9h 25mSouthwest
Deal found 4/30$354
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2812:04 pmCLT - DSM
Nonstop2h 24mAmerican Airlines
Sat 6/75:32 pmDSM - CLT
Nonstop2h 21mAmerican Airlines
Deal found 4/30$373
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2311:15 amCLT - DSM
2 stops10h 00mUnited Airlines
Sat 8/22:57 pmDSM - CLT
1 stop6h 00mUnited Airlines
Deal found 4/29$398

Cheapflights Fare Finder

Customize your flight search to find flights from Spartanburg to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Spartanburg to Des Moines that are best for you.

Fly from

Spartanburg

Fly to

Des Moines

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 6/26

11:28 am-6:11 pm

2 stops31h 43m

Des Moines

Sun 6/29

6:32 pm-4:37 pm

1 stop21h 05m

$279

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sun 9/7

5:30 am-10:14 am

1 stop5h 44m

Des Moines

Mon 9/8

2:14 pm-10:20 pm

1 stop7h 06m

$341

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 5/28

3:40 pm-10:05 pm

1 stop7h 25m

Des Moines

Fri 5/30

7:00 am-5:25 pm

1 stop9h 25m

$354

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 5/28

12:04 pm-1:28 pm

Nonstop2h 24m

Des Moines

Sat 6/7

5:32 pm-8:53 pm

Nonstop2h 21m

$373

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 7/23

11:15 am-8:15 pm

2 stops10h 00m

Des Moines

Sat 8/2

2:57 pm-9:57 pm

1 stop6h 00m

$398

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 5/30

3:40 pm-10:10 pm

1 stop7h 30m

$195

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 5/28

11:35 am-5:06 pm

1 stop6h 31m

$197

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sun 9/28

8:15 pm-11:41 pm

1 stop4h 26m

$210

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 7/23

11:15 am-8:15 pm

2 stops10h 00m

$215

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Best time to book a flight from Spartanburg to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Des Moines

How far ahead should I book a flight from Spartanburg to Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to Des Moines. Price data was last updated on April 25, 2025.

To ensure you get the cheapest price possible for a flight from Spartanburg to Des Moines, you should look to book at least 43 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Spartanburg to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Spartanburg to Des Moines (average of $336). Flying from Spartanburg to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to DSM?

Find hourly flight availability from Spartanburg to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

When flying from Spartanburg to Des Moines, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Spartanburg to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to Des Moines. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Spartanburg to Des Moines flight should consider departing on Tuesday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 30, 2025.
Southwest
8.0
Very good
4,294 reviews

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,294 reviews
Southwest
8.0
Very good
4,294 reviews

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,935 reviews
Southwest
8.0
Very good
4,294 reviews

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,294 reviews

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,294 reviews

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Spartanburg?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Des Moines from Spartanburg. Booking flights from Spartanburg to Des Moines (DSM) should be relatively easy as there are 0 daily inbound flights from Spartanburg from 3 different airlines.

  • What are the cheapest airlines to fly from Spartanburg to Des Moines one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $195. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Spartanburg to Des Moines for a low price.

  • What are the cheapest flights from Spartanburg to Des Moines?

    The cheapest flight price from Spartanburg to Des Moines is $373. On average you can expect to pay $442. The most popular route, (Charlotte Douglas - Des Moines), can usually be booked for $213.

  • Can I find deals for flights from Spartanburg to Des Moines that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Des Moines.

  • Can I find deals for business class flights from Spartanburg to Des Moines?

    Yes. Cheapflights offers flight deals from Spartanburg to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Spartanburg to Des Moines (average of $336). Flying from Spartanburg to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Spartanburg?

Book flights to Spartanburg if you plan to visit one of these locations
Ames
Altoona
Johnston
Boone
West Des Moines
Ankeny

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Top 3 airlines flying from Spartanburg to Des Moines

Discover the top 3 airlines that operate flights from Spartanburg to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$383FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$400FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$323Average$479FlexibilityNo cancel feeOn-time69%

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