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Des Moines

$72+ Cheap flights from Spartanburg, SC to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — DSM
Jun 21 — Jun 281
Sat 6/21
Sat 6/28
1 adult, Economy
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Cheapflights Tip: The best prices from Spartanburg to Des Moines are usually found in March or September, booked 33 days in advance, depart on a Tuesday or Thursday and return on a Tuesday

Cheap flight deals from Spartanburg to Des Moines

Keep the following information in mind while searching for Spartanburg to Des Moines flight deals. Data was last updated June 16, 2025.

Round-trip from

$150
(Southwest)

One-way from

$72
(Southwest)

Popular in

December

Cheapest in

March

Average price

$421
From Spartanburg to Des Moines
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One-way flight from Spartanburg to Des Moines
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Highest demand for flights based on searches. 7% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Spartanburg to Des Moines

Cheapest flights from Spartanburg to Des Moines
Explore the most affordable flight options available from Spartanburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2025.

This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/35:25 pmCLT - DSM
1 stop5h 55mSouthwest
Mon 9/86:00 amDSM - CLT
1 stop10h 35mSouthwest
Deal found 6/16$150
This Mytrip deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/76:20 amCLT - DSM
2 stops17h 18mMultiple Airlines
Sun 8/106:32 pmDSM - CLT
1 stop18h 30mMultiple Airlines
Deal found 6/15$207
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:16 pmCLT - DSM
1 stop7h 56mAmerican Airlines
Tue 11/185:56 amDSM - CLT
1 stop12h 03mAmerican Airlines
Deal found 6/14$283
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:30 amCLT - DSM
1 stop5h 48mDelta
Sun 10/52:14 pmDSM - CLT
1 stop7h 06mDelta
Deal found 6/13$324
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/3011:15 amCLT - DSM
2 stops10h 00mUnited Airlines
Fri 7/46:24 amDSM - CLT
2 stops6h 43mUnited Airlines
Deal found 6/15$371
This FlightHub deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/265:28 pmCLT - DSM
1 stop27h 25mFrontier
Mon 6/308:38 pmDSM - CLT
1 stop18h 55mFrontier
Deal found 6/14$418

Cheapflights Fare Finder

Customize your flight search to find flights from Spartanburg to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
Use the filters below to find and compare flights from Spartanburg to Des Moines that are best for you.

Fly from

Spartanburg

Fly to

Des Moines

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 9/3

5:25 pm-10:20 pm

1 stop5h 55m

Des Moines

Mon 9/8

6:00 am-5:35 pm

1 stop10h 35m

$150

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 8/7

6:20 am-10:38 pm

2 stops17h 18m

Des Moines

Sun 8/10

6:32 pm-2:02 pm

1 stop18h 30m

$207

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 11/13

1:16 pm-8:12 pm

1 stop7h 56m

Des Moines

Tue 11/18

5:56 am-6:59 pm

1 stop12h 03m

$283

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 10/2

5:30 am-10:18 am

1 stop5h 48m

Des Moines

Sun 10/5

2:14 pm-10:20 pm

1 stop7h 06m

$324

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 6/30

11:15 am-8:15 pm

2 stops10h 00m

Des Moines

Fri 7/4

6:24 am-2:07 pm

2 stops6h 43m

$371

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 6/26

5:28 pm-7:53 pm

1 stop27h 25m

Des Moines

Mon 6/30

8:38 pm-4:33 pm

1 stop18h 55m

$418

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 8/25

7:50 pm-10:50 pm

1 stop4h 00m

$72

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 7/14

9:24 am-6:06 pm

1 stop9h 42m

$95

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sat 6/28

9:40 pm-10:59 pm

Nonstop2h 19m

$411

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/13

Best time to book a flight from Spartanburg to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Des Moines

How far ahead should I book a flight from Spartanburg to Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to Des Moines. Price data was last updated on June 13, 2025.

To ensure you get the cheapest price possible for a flight from Spartanburg to Des Moines, you should look to book at least 33 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Spartanburg to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Spartanburg to Des Moines (average of $336). Flying from Spartanburg to Des Moines in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to DSM?

Find hourly flight availability from Spartanburg to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 16, 2025.

When flying from Spartanburg to Des Moines, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Spartanburg to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to Des Moines. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Spartanburg to Des Moines flight should consider departing on Tuesday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Spartanburg to Des Moines

Explore weekly flight availability from Spartanburg to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 16, 2025.

The most flights from SB1 to DSM are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 16, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Spartanburg to Des Moines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,278 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,278 reviews
Southwest
8.0
Very good
4,278 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,963 reviews
Southwest
8.0
Very good
4,278 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,801 reviews
Southwest
8.0
Very good
4,278 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,278 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Frontier
5.9
Fair
3,296 reviews
Southwest
8.0
Very good
4,278 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Spartanburg?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Des Moines from Spartanburg. Booking flights from Spartanburg to Des Moines (DSM) should be relatively easy as there are 2 daily inbound flights from Spartanburg from 3 different airlines.

  • What are the cheapest flights from Spartanburg to Des Moines?

    The cheapest flight price from Spartanburg to Des Moines is $386. On average you can expect to pay $462. The most popular route, (Charlotte Douglas - Des Moines), can usually be booked for $207.

  • Can I find deals for flights from Spartanburg to Des Moines that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Des Moines.

  • Can I find deals for business class flights from Spartanburg to Des Moines?

    Yes. Cheapflights offers flight deals from Spartanburg to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Spartanburg to Des Moines (average of $336). Flying from Spartanburg to Des Moines in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Spartanburg?

Book flights to Spartanburg if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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Top 3 airlines flying from Spartanburg to Des Moines

Discover the top 3 airlines that operate flights from Spartanburg to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$216Average$378FlexibilityNo cancel feeOn-time71%
DeltaCheapest$232Average$384FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$323Average$389FlexibilityNo cancel feeOn-time69%

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