How long is the flight from Spartanburg to Des Moines?

A quick flight from Spartanburg to Des Moines can take about 2h 46m. American Airlines provides one of the quickest options available for as low as $373. The distance between Spartanburg and Des Moines is about 813 mi. All flights are typically nonstop.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What are the cheapest flights from Spartanburg to Des Moines?

The cheapest flight price from Spartanburg to Des Moines is $439. On average you can expect to pay $483. The most popular route, (Charlotte Douglas - Des Moines), can usually be booked for $232.

What airport do you fly into for flights to Des Moines from Spartanburg?

Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Des Moines from Spartanburg. Booking flights from Spartanburg to Des Moines (DSM) should be relatively easy as there are 0 daily inbound flights from Spartanburg from 3 different airlines.

Can I find deals for flights from Spartanburg to Des Moines that include hotel bookings?

Yes. In addition to deals on Spartanburg to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Spartanburg to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Des Moines.

Can I find deals for business class flights from Spartanburg to Des Moines?

Yes. Cheapflights offers flight deals from Spartanburg to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$114+ Flights from Spartanburg to Des Moines

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Cheapflights Tip: The best prices from Spartanburg to Des Moines are usually found in March or September, booked 65 days in advance, depart on a Tuesday or Thursday and return on a Wednesday

Cheap flight deals from Spartanburg to Des Moines

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$204 (Kiwi.com)
One-way from	$114 (Kiwi.com)
Popular in	December
Cheapest in	March
Average price	$421

Provider with most accurate pricing for Charlotte Douglas-Des Moines flight deals.

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From Spartanburg to Des Moines

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One-way flight from Spartanburg to Des Moines

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Highest demand for flights based on searches. 7% potential increase in price ($34 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

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Average for round-trip flights in October 2025

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Find flight deals from Spartanburg to Des Moines

Cheapest flights from Spartanburg to Des Moines
Explore the most affordable flight options available from Spartanburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Tue 11/253:11 pmCLT - DSM

1 stop9h 13mMultiple Airlines

Mon 12/16:53 pmDSM - CLT

1 stop18h 13mMultiple Airlines

Deal found 10/28

$232

Wed 11/2611:56 amCLT - DSM

1 stop27h 10mMultiple Airlines

Mon 12/16:53 pmDSM - CLT

1 stop18h 13mMultiple Airlines

Deal found 10/27

$264

Mon 11/247:15 amCLT - DSM

2 stops31h 16mMultiple Airlines

Mon 12/16:53 pmDSM - CLT

1 stop18h 13mMultiple Airlines

Deal found 10/27

$267

Fri 11/216:00 amCLT - DSM

1 stop7h 55mMultiple Airlines

Mon 11/246:40 amDSM - CLT

1 stop7h 16mMultiple Airlines

Deal found 10/28

$289

Fri 11/75:45 amCLT - DSM

1 stop10h 10mMultiple Airlines

Mon 11/108:40 amDSM - CLT

2 stops33h 14mMultiple Airlines

Deal found 10/28

$294

Sat 11/86:44 pmCLT - DSM

1 stop16h 16mMultiple Airlines

Mon 11/108:40 amDSM - CLT

2 stops33h 14mMultiple Airlines

Deal found 10/28

$297

Best flights from Spartanburg to Des Moines
Discover carefully curated flight deals from Spartanburg to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2025.

Fri 11/216:00 amCLT - DSM

1 stop7h 55mMultiple Airlines

Mon 11/249:34 amDSM - CLT

3 stops27h 32mMultiple Airlines

Deal found 10/28

$368

Tue 11/2510:35 pmCLT - DSM

Nonstop2h 46mAmerican Airlines

Tue 12/25:04 pmDSM - CLT

Nonstop2h 31mAmerican Airlines

Deal found 10/26

$373

Tue 11/257:57 amCLT - DSM

1 stop6h 35mDelta

Tue 12/26:33 pmDSM - CLT

1 stop4h 09mDelta

Deal found 10/26

$393

Mon 12/11:20 pmCLT - DSM

2 stops11h 45mSouthwest

Mon 12/86:15 amDSM - CLT

2 stops9h 05mSouthwest

Deal found 10/26

$421

Sat 12/2710:46 pmCLT - DSM

Nonstop2h 51mAmerican Airlines

Sat 1/31:59 pmDSM - CLT

Nonstop2h 23mAmerican Airlines

Deal found 10/29

$373

Tue 11/256:00 amCLT - DSM

3 stops18h 24mMultiple Airlines

Mon 12/16:53 pmDSM - CLT

3 stops27h 15mMultiple Airlines

Deal found 10/28

$391

Mon 12/17:30 amCLT - DSM

1 stop11h 33mMultiple Airlines

Mon 12/86:35 amDSM - CLT

1 stop28h 29mMultiple Airlines

Deal found 10/26

$395

Mon 11/246:01 pmCLT - DSM

1 stop6h 43mAmerican Airlines

Sat 11/296:39 amDSM - CLT

Nonstop2h 41mAmerican Airlines

Deal found 10/27

$428

Mon 11/247:15 amCLT - DSM

2 stops31h 16mMultiple Airlines

Sat 11/298:59 amDSM - CLT

1 stop22h 00mMultiple Airlines

Deal found 10/27

$421

Tue 11/253:11 pmCLT - DSM

1 stop9h 13mMultiple Airlines

Sat 11/296:14 pmDSM - CLT

2 stops45h 59mMultiple Airlines

Deal found 10/28

$427

Last-minute flights from Spartanburg to Des Moines
Discover last-minute flight deals from Spartanburg to Des Moines. Data last updated October 29, 2025 and is based on user searches.

Fri 11/75:45 amCLT - DSM

1 stop10h 10mMultiple Airlines

Mon 11/108:40 amDSM - CLT

2 stops33h 14mMultiple Airlines

Deal found 10/28

$294

Sat 11/86:44 pmCLT - DSM

1 stop16h 16mMultiple Airlines

Mon 11/108:40 amDSM - CLT

2 stops33h 14mMultiple Airlines

Deal found 10/28

$297

Fri 11/216:00 amCLT - DSM

1 stop7h 55mMultiple Airlines

Mon 11/246:40 amDSM - CLT

1 stop7h 16mMultiple Airlines

Deal found 10/28

$289

Mon 11/247:15 amCLT - DSM

2 stops31h 16mMultiple Airlines

Mon 12/16:53 pmDSM - CLT

1 stop18h 13mMultiple Airlines

Deal found 10/27

$267

Tue 11/253:11 pmCLT - DSM

1 stop9h 13mMultiple Airlines

Mon 12/16:53 pmDSM - CLT

1 stop18h 13mMultiple Airlines

Deal found 10/28

$232

Wed 11/2611:56 amCLT - DSM

1 stop27h 10mMultiple Airlines

Mon 12/16:53 pmDSM - CLT

1 stop18h 13mMultiple Airlines

Deal found 10/27

$264

One-way flights from Spartanburg to Des Moines
Search for one-way flight options from Spartanburg to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 29, 2025.

Tue 11/2510:13 amCLT - DSM

1 stop14h 11mMultiple Airlines

Deal found 10/28

$114

Mon 11/245:59 pmCLT - DSM

1 stop30h 25mMultiple Airlines

Deal found 10/28

$116

Thu 1/229:49 amCLT - DSM

1 stop13h 57mMultiple Airlines

Deal found 10/27

$124

Sun 11/166:02 pmCLT - DSM

1 stop20h 45mFrontier

Deal found 10/28

$126

Sat 1/2410:32 amCLT - DSM

2 stops36h 37mMultiple Airlines

Deal found 10/27

$141

Tue 12/307:00 amCLT - DSM

1 stop17h 10mMultiple Airlines

Deal found 10/28

$156

Wed 12/319:04 pmCLT - DSM

3 stops42h 54mMultiple Airlines

Deal found 10/28

$158

Cheapflights Fare Finder

Use the filters below to find and compare flights from Spartanburg to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 11/21

6:00 am-12:55 pm

1 stop7h 55m

Des Moines

Mon 11/24

9:34 am-2:06 pm

3 stops27h 32m

$368

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 11/25

10:35 pm-12:21 am

Nonstop2h 46m

Des Moines

Tue 12/2

5:04 pm-8:35 pm

Nonstop2h 31m

$373

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sat 12/27

10:46 pm-12:37 am

Nonstop2h 51m

Des Moines

Sat 1/3

1:59 pm-5:22 pm

Nonstop2h 23m

$373

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 11/25

6:00 am-11:24 pm

3 stops18h 24m

Des Moines

Mon 12/1

6:53 pm-11:08 pm

3 stops27h 15m

$391

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 11/25

7:57 am-1:32 pm

1 stop6h 35m

Des Moines

Tue 12/2

6:33 pm-11:42 pm

1 stop4h 09m

$393

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 12/1

7:30 am-6:03 pm

1 stop11h 33m

Des Moines

Mon 12/8

6:35 am-12:04 pm

1 stop28h 29m

$395

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 12/1

1:20 pm-12:05 am

2 stops11h 45m

Des Moines

Mon 12/8

6:15 am-4:20 pm

2 stops9h 05m

$421

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 11/24

7:15 am-1:31 pm

2 stops31h 16m

Des Moines

Sat 11/29

8:59 am-7:59 am

1 stop22h 00m

$421

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 11/25

3:11 pm-11:24 pm

1 stop9h 13m

Des Moines

Sat 11/29

6:14 pm-5:13 pm

2 stops45h 59m

$427

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 11/24

6:01 pm-11:44 pm

1 stop6h 43m

Des Moines

Sat 11/29

6:39 am-10:20 am

Nonstop2h 41m

$428

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 19 results

Best time to book a flight from Spartanburg to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Spartanburg with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Des Moines

How far ahead should I book a flight from Spartanburg to Des Moines?

To ensure you get the cheapest price possible for a flight from Spartanburg to Des Moines, you should look to book at least 63 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Spartanburg to Des Moines?

Currently, November is the cheapest month in which you can book a flight from Spartanburg to Des Moines (average of $157). Flying from Spartanburg to Des Moines in December is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to DSM?

When flying from Spartanburg to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 8% versus a flight in the evening.

What is the cheapest day to fly from Spartanburg to Des Moines?

Travelers seeking maximum savings on their Spartanburg to Des Moines flight should consider departing on Saturday afternoons when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Des Moines

Get a feel of what it's like to fly with Delta and American Airlines from Spartanburg to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

7,992 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Delta

7.9

Good

7,992 reviews

Delta

7.9

Good

7,992 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

American Airlines

7.2

Good

11,032 reviews

Delta

7.9

Good

7,992 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

Related info for your journey

What airport do you fly into for flights to Des Moines from Spartanburg?
Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Des Moines from Spartanburg. Booking flights from Spartanburg to Des Moines (DSM) should be relatively easy as there are 0 daily inbound flights from Spartanburg from 3 different airlines.
How long is the flight from Spartanburg to Des Moines?
A quick flight from Spartanburg to Des Moines can take about 2h 46m. American Airlines provides one of the quickest options available for as low as $373. The distance between Spartanburg and Des Moines is about 813 mi. All flights are typically nonstop.
What are the cheapest flights from Spartanburg to Des Moines?
The cheapest flight price from Spartanburg to Des Moines is $439. On average you can expect to pay $483. The most popular route, (Charlotte Douglas - Des Moines), can usually be booked for $232.
Can I find deals for flights from Spartanburg to Des Moines that include hotel bookings?
Yes. In addition to deals on Spartanburg to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Spartanburg to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Des Moines.
Can I find deals for business class flights from Spartanburg to Des Moines?
Yes. Cheapflights offers flight deals from Spartanburg to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Spartanburg to Des Moines?
Currently, November is the cheapest month in which you can book a flight from Spartanburg to Des Moines (average of $157). Flying from Spartanburg to Des Moines in December is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Johnston

Altoona

Boone

Ames

West Des Moines

Ankeny

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Other flights to Des Moines

Top 3 airlines flying from Spartanburg to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$216	Average$374	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$248	Average$490	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$248	Average$382	FlexibilityNo cancel fee	On-time71%

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$114+ Cheap flights from Spartanburg, SC to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Spartanburg to Des Moines with Cheapflights

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3. Compare prices and book

Cheapflights Tip: The best prices from Spartanburg to Des Moines are usually found in March or September, booked 65 days in advance, depart on a Tuesday or Thursday and return on a Wednesday

Cheap flight deals from Spartanburg to Des Moines

Keep the following information in mind while searching for Spartanburg to Des Moines flight deals. Data was last updated October 29, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Spartanburg to Des Moines

Cheapest flights from Spartanburg to Des MoinesExplore the most affordable flight options available from Spartanburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Explore the most affordable flight options available from Spartanburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Spartanburg to Des Moines that are best for you.

Best time to book a flight from Spartanburg to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Spartanburg with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Des Moines

How far ahead should I book a flight from Spartanburg to Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to Des Moines. Price data was last updated on October 24, 2025.

What is the cheapest month to book a flight from Spartanburg to Des Moines?

What is the cheapest time of day to fly from SB1 to DSM?

Find hourly flight availability from Spartanburg to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

What is the cheapest day to fly from Spartanburg to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to Des Moines. Price data was last updated on December 16, 2024.

Reviews of airlines servicing Des Moines

Get a feel of what it's like to fly with Delta and American Airlines from Spartanburg to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Des Moines from Spartanburg?

How long is the flight from Spartanburg to Des Moines?

What are the cheapest flights from Spartanburg to Des Moines?

Can I find deals for flights from Spartanburg to Des Moines that include hotel bookings?

How can I find direct flights from Spartanburg to Des Moines?

Can I find deals for business class flights from Spartanburg to Des Moines?

What is the cheapest month to book a flight from Spartanburg to Des Moines?

Traveling to a place near Des Moines?

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Alternative routes for Spartanburg to Des Moines

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Top 3 airlines flying from Spartanburg to Des Moines

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Cheapest flights from Spartanburg to Des Moines
Explore the most affordable flight options available from Spartanburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.