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Des Moines

$216+ Cheap flights from Pensacola to Des Moines (PNS - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
PNS — DSM
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Pensacola to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Pensacola (PNS) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$257
(United Airlines)

One-way from

$216
(Kiwi.com)

Popular in

May

Cheapest in

August

Average price

$504
From Pensacola to Des Moines
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One-way flight from Pensacola to Des Moines
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Highest demand for flights based on searches. 38% potential increase in price ($321 potential increase over avg. RT price).
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Cheapest flight prices on average. 19% potential price decrease ($83 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Pensacola to Des Moines

Cheapest flights from Pensacola to Des Moines
Explore the most affordable flight options available from Pensacola to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:00 amPNS - DSM
1 stop7h 13mUnited Airlines
Sat 10/188:00 amDSM - PNS
1 stop5h 15mUnited Airlines
Deal found 9/13$257
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1111:13 amPNS - DSM
2 stops8h 58mAmerican Airlines
Sat 10/181:48 pmDSM - PNS
2 stops8h 44mAmerican Airlines
Deal found 9/13$267
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/164:39 pmPNS - DSM
1 stop7h 20mAmerican Airlines
Mon 10/205:04 amDSM - PNS
1 stop7h 33mAmerican Airlines
Deal found 9/14$279
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/43:00 pmPNS - DSM
1 stop7h 28mUnited Airlines
Sat 10/183:05 pmDSM - PNS
1 stop6h 54mUnited Airlines
Deal found 9/13$287
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/46:00 amPNS - DSM
2 stops11h 42mDelta
Sat 10/185:15 pmDSM - PNS
1 stop4h 32mDelta
Deal found 9/13$292
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/183:57 pmPNS - DSM
1 stop5h 59mAmerican Airlines
Sun 10/195:00 amDSM - PNS
1 stop5h 01mAmerican Airlines
Deal found 9/14$322
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:10 pmPNS - DSM
1 stop13h 19mMultiple Airlines
Sun 10/1210:41 amDSM - PNS
1 stop28h 50mMultiple Airlines
Deal found 9/13$332
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:21 pmPNS - DSM
1 stop20h 19mMultiple Airlines
Sun 10/1210:41 amDSM - PNS
1 stop28h 50mMultiple Airlines
Deal found 9/13$338

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pensacola to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Pensacola to Des Moines that are best for you.

Fly from

Pensacola

Fly to

Des Moines

Route

Depart

Return

Price

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Sat 10/11

7:00 am-2:13 pm

1 stop7h 13m

Des Moines

Sat 10/18

8:00 am-1:15 pm

1 stop5h 15m

$257

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Sat 10/11

11:13 am-8:11 pm

2 stops8h 58m

Des Moines

Sat 10/18

1:48 pm-10:32 pm

2 stops8h 44m

$267

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Thu 10/16

1:27 pm-6:46 pm

1 stop5h 19m

Des Moines

Mon 10/20

5:04 am-10:01 am

1 stop4h 57m

$279

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Sat 10/4

3:00 pm-10:28 pm

1 stop7h 28m

Des Moines

Sat 10/18

3:05 pm-9:59 pm

1 stop6h 54m

$287

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Sat 10/4

6:00 am-5:42 pm

2 stops11h 42m

Des Moines

Sat 10/18

5:15 pm-9:47 pm

1 stop4h 32m

$292

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Fri 10/3

7:10 pm-8:29 am

1 stop13h 19m

Des Moines

Sun 10/12

10:41 am-3:31 pm

1 stop28h 50m

$332

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Sat 10/4

5:21 pm-1:40 pm

1 stop20h 19m

Des Moines

Sun 10/12

10:41 am-3:31 pm

1 stop28h 50m

$338

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Tue 9/30

7:10 pm-9:51 am

2 stops38h 41m

$216

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Tue 9/30

5:00 pm-10:28 pm

1 stop5h 28m

$224

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Tue 9/30

8:00 am-1:20 pm

1 stop5h 20m

$224

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 15 results
1
2

Best time to book a flight from Pensacola to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Pensacola with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pensacola to Des Moines

What is the cheapest month to book a flight from Pensacola to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Pensacola to Des Moines (average of $336). Flying from Pensacola to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PNS to DSM?

Find hourly flight availability from Pensacola to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

It’s typically best to fly out from Pensacola to Des Moines at noon. Doing so could potentially save you 10% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Pensacola to Des Moines to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Pensacola to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Pensacola to Des Moines?

    Departing from Pensacola to Des Moines will take you 7h 13m. Pensacola and Des Moines are separated by a distance of 845 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Pensacola to Des Moines round-trip?

    Currently priced at $236, American Airlines will fly you from Pensacola to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $246. American Airlines is priced at 53% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Pensacola to Des Moines one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $224. Users have also found prices from $224 and $250 on Delta and Frontier, respectively.

  • Can I find deals for flights from Pensacola to Des Moines that include hotel bookings?

    Yes. In addition to deals on Pensacola to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pensacola to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pensacola to Des Moines.

  • Can I find deals for business class flights from Pensacola to Des Moines?

    Yes. Cheapflights offers flight deals from Pensacola to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Pensacola to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Pensacola to Des Moines (average of $336). Flying from Pensacola to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top 2 airlines flying from Pensacola to Des Moines

Discover the top 2 airlines that operate flights from Pensacola to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$361FlexibilityNo cancel feeOn-time71%
DeltaCheapest$246Average$334FlexibilityNo cancel feeOn-timeN/A

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