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Des Moines

$170+ Cheap flights from Pensacola to Des Moines (PNS - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
PNS — DSM
Mar 28 — Apr 41
Sat 3/28
Sat 4/4
1 adult, Economy
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Cheap flight deals from Pensacola to Des Moines

Cheapest flights from Pensacola to Des Moines
Explore the most affordable flight options available from Pensacola to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 26, 2026.

This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:54 pm
PNS
-
DSM
1 stop5h 49m
United Airlines
Fri 4/33:04 pm
DSM
-
PNS
1 stop6h 53m
United Airlines
Deal found 2/24$352
This Southwest deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:30 am
PNS
-
DSM
2 stops8h 10m
Southwest
Tue 4/75:30 am
DSM
-
PNS
2 stops8h 35m
Southwest
Deal found 2/25$353
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:38 pm
PNS
-
DSM
1 stop6h 04m
American Airlines
Wed 4/81:25 pm
DSM
-
PNS
1 stop7h 59m
American Airlines
Deal found 2/25$356
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:16 am
PNS
-
DSM
1 stop4h 39m
Delta
Mon 5/46:31 pm
DSM
-
PNS
1 stop4h 52m
Delta
Deal found 2/23$364
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:42 pm
PNS
-
DSM
1 stop6h 17m
American Airlines
Mon 5/411:09 am
DSM
-
PNS
2 stops8h 23m
American Airlines
Deal found 2/23$369
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/55:23 am
PNS
-
DSM
1 stop7h 44m
American Airlines
Sat 4/113:20 pm
DSM
-
PNS
1 stop7h 05m
American Airlines
Deal found 2/24$373
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:00 am
PNS
-
DSM
1 stop4h 48m
Delta
Tue 4/75:20 pm
DSM
-
PNS
1 stop5h 53m
Delta
Deal found 2/25$376

Find flight deals from Pensacola to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Pensacola (PNS) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$352
(United Airlines)

One-way from

$170
(Kiwi.com)

Popular in

May

Cheapest in

October

Average price

$424
Provider with most accurate pricing for Pensacola-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Pensacola-Des Moines flights.
Search Deals
From Pensacola to Des Moines
Search Deals
One-way flight from Pensacola to Des Moines
Search Deals
Highest demand for flights based on searches. 36% potential increase in price ($303 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 20% potential price decrease ($89 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pensacola to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 26, 2026.
Use the filters below to find and compare flights from Pensacola to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Wed 4/1

4:00 pm-11:42 pm

1 stop7h 42m

Des Moines

Fri 4/3

3:04 pm-9:57 pm

1 stop6h 53m

$352

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Tue 3/31

4:54 pm-10:43 pm

1 stop5h 49m

Des Moines

Fri 4/3

3:04 pm-9:57 pm

1 stop6h 53m

$352

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Mon 4/6

5:30 am-1:40 pm

2 stops8h 10m

Des Moines

Tue 4/7

5:30 am-2:05 pm

2 stops8h 35m

$353

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Mon 4/6

5:30 am-1:40 pm

2 stops8h 10m

Des Moines

Wed 4/8

5:30 am-2:05 pm

2 stops8h 35m

$353

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Fri 5/1

5:42 pm-11:59 pm

1 stop6h 17m

Des Moines

Mon 5/4

11:09 am-7:32 pm

2 stops8h 23m

$369

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Sun 4/5

6:15 am-4:15 pm

2 stops10h 00m

Des Moines

Sat 4/11

11:25 am-8:00 pm

2 stops8h 35m

$386

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Fri 3/27

7:00 am-2:24 pm

1 stop7h 24m

Des Moines

Fri 4/3

1:32 pm-9:57 pm

2 stops8h 25m

$392

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Sat 8/15

7:00 am-4:14 pm

2 stops9h 14m

Des Moines

Sat 8/22

8:00 am-4:06 pm

2 stops8h 06m

$397

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Fri 3/27

12:00 pm-11:15 pm

2 stops11h 15m

Des Moines

Fri 4/3

6:50 am-5:20 pm

2 stops10h 30m

$417

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Sun 4/5

6:15 am-2:22 pm

1 stop8h 07m

Des Moines

Tue 4/7

3:04 pm-9:57 pm

1 stop6h 53m

$446

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/23

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Compare providers for flights from Pensacola to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Pensacola to Des Moines in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Pensacola-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Pensacola-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Pensacola-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Pensacola-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Pensacola-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Pensacola to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Pensacola with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated February 26, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Pensacola to Des Moines to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,242 reviews

Food

7.2

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,242 reviews
Delta
7.9
Good
8,242 reviews

Food

7.2

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,357 reviews
Delta
7.9
Good
8,242 reviews

Food

7.2

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Pensacola to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Pensacola to Des Moines?

    Departing from Pensacola to Des Moines will take you 7h 42m. Pensacola and Des Moines are separated by a distance of 845 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Pensacola to Des Moines round-trip?

    Currently priced at $236, American Airlines will fly you from Pensacola to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $246. American Airlines is priced at 55% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Pensacola to Des Moines that include hotel bookings?

    Yes. In addition to deals on Pensacola to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pensacola to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pensacola to Des Moines.

  • Can I find deals for business class flights from Pensacola to Des Moines?

    Yes. Cheapflights offers flight deals from Pensacola to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Boone
Ames
Clive
West Des Moines

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Top 2 airlines flying from Pensacola to Des Moines

Discover the top 2 airlines that operate flights from Pensacola to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$424FlexibilityNo cancel feeOn-time71%
DeltaCheapest$246Average$334FlexibilityNo cancel feeOn-timeN/A

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