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Des Moines

$159+ Cheap flights from Pensacola to Des Moines (PNS - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
PNS — DSM
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheap flight deals from Pensacola to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Pensacola (PNS) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$322
(Mytrip)

One-way from

$159
(Delta)

Popular in

May

Cheapest in

October

Average price

$466
Provider with most accurate pricing for Pensacola-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Pensacola-Des Moines flights.
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From Pensacola to Des Moines
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One-way flight from Pensacola to Des Moines
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Highest demand for flights based on searches. 37% potential increase in price ($313 potential increase over avg. RT price).
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Cheapest flight prices on average. 18% potential price decrease ($82 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Pensacola to Des Moines

Cheapest flights from Pensacola to Des Moines
Explore the most affordable flight options available from Pensacola to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/103:12 pmPNS - DSM
1 stop7h 17mUnited Airlines
Tue 12/168:15 amDSM - PNS
1 stop5h 43mUnited Airlines
Deal found 11/13$387
This Mytrip deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:16 pmPNS - DSM
2 stops20h 22mMultiple Airlines
Mon 11/248:00 amDSM - PNS
3 stops35h 11mMultiple Airlines
Deal found 11/12$482
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/213:44 pmPNS - DSM
1 stop6h 49mDelta
Mon 11/242:17 pmDSM - PNS
1 stop5h 53mDelta
Deal found 11/12$492
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:24 amPNS - DSM
2 stops7h 58mAmerican Airlines
Mon 11/243:18 pmDSM - PNS
1 stop5h 11mAmerican Airlines
Deal found 11/12$497
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/287:00 amPNS - DSM
1 stop5h 14mUnited Airlines
Tue 12/28:00 amDSM - PNS
1 stop5h 17mUnited Airlines
Deal found 11/13$537
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:29 amPNS - DSM
1 stop5h 32mAmerican Airlines
Sun 12/285:07 amDSM - PNS
1 stop5h 32mAmerican Airlines
Deal found 11/13$543
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:32 amPNS - DSM
1 stop5h 09mAmerican Airlines
Sun 11/305:00 amDSM - PNS
1 stop5h 43mAmerican Airlines
Deal found 11/11$603

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pensacola to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Pensacola to Des Moines that are best for you.

Fly from

Pensacola

Fly to

Des Moines

Route

Depart

Return

Price

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Thu 1/15

4:03 pm-10:46 pm

1 stop6h 43m

Des Moines

Thu 1/29

4:30 pm-3:08 pm

2 stops22h 38m

$322

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Thu 1/15

7:00 am-3:15 pm

1 stop8h 15m

Des Moines

Thu 1/29

1:16 pm-9:43 pm

1 stop8h 27m

$341

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Wed 12/10

4:55 pm-10:29 pm

1 stop5h 34m

Des Moines

Tue 12/16

8:00 am-1:16 pm

1 stop5h 16m

$387

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Tue 3/10

5:34 am-12:31 pm

1 stop6h 57m

Des Moines

Wed 3/11

6:56 am-3:17 pm

1 stop8h 21m

$389

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Tue 1/6

6:00 am-10:41 am

1 stop4h 41m

$159

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Tue 1/6

6:42 am-4:24 pm

2 stops9h 42m

$164

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Thu 12/18

11:46 am-5:47 pm

1 stop6h 01m

$171

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Fri 11/28

5:54 pm-8:09 am

1 stop14h 15m

$179

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Tue 5/12

6:00 am-10:16 am

1 stop4h 16m

$194

PensacolaDes Moines

PNS - DSM

PNSDSM

Pensacola

Tue 1/6

1:58 pm-3:40 pm

3 stops49h 42m

$214

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 12 results
1
2

Compare providers for flights from Pensacola to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Pensacola to Des Moines in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Pensacola-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Pensacola-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Pensacola-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Pensacola-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Pensacola-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Pensacola to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Pensacola with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pensacola to Des Moines

What is the cheapest month to book a flight from Pensacola to Des Moines?

Currently, March is the cheapest month in which you can book a flight from Pensacola to Des Moines (average of $236). Flying from Pensacola to Des Moines in December is currently the most expensive (average of $717). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated November 13, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Pensacola to Des Moines to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Food

7.3

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Pensacola to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Pensacola to Des Moines?

    Departing from Pensacola to Des Moines will take you 5h 34m. Pensacola and Des Moines are separated by a distance of 845 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Pensacola to Des Moines round-trip?

    Currently priced at $236, American Airlines will fly you from Pensacola to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $246. American Airlines is priced at 54% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Pensacola to Des Moines that include hotel bookings?

    Yes. In addition to deals on Pensacola to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pensacola to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pensacola to Des Moines.

  • Can I find deals for business class flights from Pensacola to Des Moines?

    Yes. Cheapflights offers flight deals from Pensacola to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Pensacola to Des Moines?

    Currently, March is the cheapest month in which you can book a flight from Pensacola to Des Moines (average of $236). Flying from Pensacola to Des Moines in December is currently the most expensive (average of $717). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top 2 airlines flying from Pensacola to Des Moines

Discover the top 2 airlines that operate flights from Pensacola to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$407FlexibilityNo cancel feeOn-time71%
DeltaCheapest$246Average$318FlexibilityNo cancel feeOn-timeN/A

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