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Des Moines

$149+ Cheap flights from Myrtle Beach to Des Moines (MYR - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/9. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — DSM
juin 17 — juin 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated juin 12, 2025.

Round-trip from

$264
(Mytrip)

One-way from

$149
(Delta)
From Myrtle Beach Intl to Des Moines
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One-way flight from Myrtle Beach Intl to Des Moines
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Find flight deals from Myrtle Beach to Des Moines

Cheapest flights from Myrtle Beach to Des Moines
Explore the most affordable flight options available from Myrtle Beach to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juin 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 7/247:34 pmMYR - DSM
1 stop18h 12mMultiple Airlines
dim. 7/276:32 pmDSM - MYR
2 stops26h 45mMultiple Airlines
Deal found 6/10$264
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 8/17:50 pmMYR - DSM
1 stop4h 11mAmerican Airlines
lun. 8/115:29 pmDSM - MYR
1 stop4h 42mAmerican Airlines
Deal found 6/12$319
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/174:55 pmMYR - DSM
1 stop5h 27mUnited Airlines
mer. 6/258:00 amDSM - MYR
1 stop5h 35mUnited Airlines
Deal found 6/9$566
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/171:25 pmMYR - DSM
2 stops8h 12mDelta
mar. 6/246:07 amDSM - MYR
2 stops8h 07mDelta
Deal found 6/9$576
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 6/153:10 pmMYR - DSM
2 stops9h 55mSouthwest
lun. 6/235:25 amDSM - MYR
2 stops10h 50mSouthwest
Deal found 6/9$715

Cheapflights Fare Finder

Customize your flight search to find flights from Myrtle Beach to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juin 12, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Des Moines that are best for you.

Fly from

Myrtle Beach

Fly to

Des Moines

Route

Depart

Return

Price

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

jeu. 7/24

7:34 pm-12:46 pm

1 stop18h 12m

Des Moines

dim. 7/27

6:32 pm-10:17 pm

2 stops26h 45m

$264

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

ven. 8/1

6:16 pm-11:01 pm

1 stop5h 45m

Des Moines

lun. 8/11

8:17 am-3:23 pm

1 stop6h 06m

$319

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

ven. 6/27

5:12 pm-5:49 pm

2 stops25h 37m

Des Moines

mar. 7/1

8:00 am-2:35 pm

1 stop5h 35m

$647

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

mer. 7/9

6:00 am-10:39 am

1 stop5h 39m

$149

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

mer. 7/9

7:20 am-10:38 pm

2 stops40h 18m

$153

Myrtle BeachDes Moines

MYR - DSM

MYRDSM

Myrtle Beach Intl

mer. 7/9

4:12 pm-11:44 pm

2 stops8h 32m

$154

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from Myrtle Beach to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Des Moines

What is the cheapest month to book a flight from Myrtle Beach to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Des Moines (average of $336). Flying from Myrtle Beach to Des Moines in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to DSM?

Find hourly flight availability from Myrtle Beach to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated juin 12, 2025.

When flying from Myrtle Beach to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 4% versus a flight at noon.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated juin 12, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines and American Airlines from Myrtle Beach to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Myrtle Beach to Des Moines round-trip?

    American Airlines, at $319, was found to be the cheapest airline from Myrtle Beach to Des Moines. An alternate airline flying to your destination would be United Airlines.

  • Can I find deals for flights from Myrtle Beach to Des Moines that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Des Moines.

  • Can I find deals for business class flights from Myrtle Beach to Des Moines?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Des Moines (average of $336). Flying from Myrtle Beach to Des Moines in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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Top airline flying from Myrtle Beach to Des Moines

Discover the top airline that operate flights from Myrtle Beach to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juin 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$287Average$306FlexibilityNo cancel feeOn-time71%

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