$283+ Cheap flights from Medford to Des Moines (MFR - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — DSM
Oct 11 — Oct 181
Round-trip
1 adult, Economy
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Find cheap flights from Medford to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to Des Moines
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Cheapest flights from Medford to Des MoinesExplore the most affordable flight options available from Medford to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from Medford to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:00 am -
1 stop5h 31m
Sun 10/185:45 am -
2 stops8h 05m
Deal found 9/10![United Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:28 pm -
2 stops14h 03m
Fri 10/305:12 pm -
1 stop6h 06m
Deal found 9/7![United Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:05 pm -
1 stop29h 36m
Wed 10/72:42 pm -
1 stop27h 17m
Deal found 9/10![Allegiant Air logo]()
$367
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:15 am -
1 stop5h 47m
Tue 10/63:46 pm -
2 stops9h 32m
Deal found 9/10![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:16 am -
1 stop6h 33m
Sun 10/186:29 pm -
1 stop6h 57m
Deal found 9/10![American Airlines logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:05 pm -
1 stop29h 36m
Sun 10/41:22 pm -
1 stop8h 45m
Deal found 9/10![Allegiant Air logo]()
$397
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:20 pm -
2 stops19h 51m
Sat 10/174:01 pm -
2 stops9h 17m
Deal found 9/10![Delta logo]()
$400
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:00 am -
1 stop5h 31m
Wed 10/75:45 am -
2 stops8h 05m
Deal found 9/10![United Airlines logo]()
$416
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:05 pm -
2 stops28h 28m
Wed 10/72:42 pm -
1 stop27h 17m
Deal found 9/10![Multiple Airlines logo]()
$422
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:49 pm -
1 stop16h 08m
Sun 10/1810:09 pm -
1 stop14h 04m
Deal found 9/10![Allegiant Air logo]()
$423
Best flights from Medford to Des MoinesDiscover carefully curated flight deals from Medford to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from Medford to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:28 pm -
2 stops14h 03m
Fri 10/305:12 pm -
1 stop6h 06m
Deal found 9/7![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:11 am -
2 stops12h 49m
Tue 10/203:46 pm -
2 stops9h 32m
Deal found 9/10![Delta logo]()
$400
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:20 pm -
2 stops20h 22m
Sat 10/174:01 pm -
2 stops9h 17m
Deal found 9/10![Delta logo]()
$400
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:00 am -
1 stop5h 31m
Sat 10/175:22 pm -
1 stop5h 52m
Deal found 9/10![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/236:00 am -
2 stops12h 32m
Wed 1/279:37 am -
2 stops12h 18m
Deal found 9/8![United Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:01 pm -
2 stops8h 34m
Mon 9/285:22 pm -
1 stop5h 52m
Deal found 9/9![United Airlines logo]()
$523
Last-minute flights from Medford to Des MoinesDiscover last-minute flight deals from Medford to Des Moines. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to Des Moines. Data last updated September 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:05 pm -
1 stop29h 36m
Wed 10/72:42 pm -
1 stop27h 17m
Deal found 9/10![Allegiant Air logo]()
$367
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:15 am -
1 stop5h 47m
Tue 10/63:46 pm -
2 stops9h 32m
Deal found 9/10![Delta logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:05 pm -
1 stop29h 36m
Sun 10/41:22 pm -
1 stop8h 45m
Deal found 9/10![Allegiant Air logo]()
$397
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:05 pm -
2 stops28h 28m
Wed 10/72:42 pm -
1 stop27h 17m
Deal found 9/10![Multiple Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:00 am -
1 stop5h 31m
Wed 10/75:45 am -
2 stops8h 05m
Deal found 9/10![United Airlines logo]()
$416
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:20 pm -
2 stops19h 51m
Sat 10/174:01 pm -
2 stops9h 17m
Deal found 9/10![Delta logo]()
$400
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:00 am -
1 stop5h 31m
Sun 10/185:45 am -
2 stops8h 05m
Deal found 9/10![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:16 am -
1 stop6h 33m
Sun 10/186:29 pm -
1 stop6h 57m
Deal found 9/10![American Airlines logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:49 pm -
1 stop16h 08m
Sun 10/1810:09 pm -
1 stop14h 04m
Deal found 9/10![Allegiant Air logo]()
$423
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:28 pm -
2 stops14h 03m
Fri 10/305:12 pm -
1 stop6h 06m
Deal found 9/7![United Airlines logo]()
$364
One-way flights from Medford to Des MoinesSearch for one-way flight options from Medford to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
Search for one-way flight options from Medford to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:41 pm -
3 stops39h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$283
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:04 am -
1 stop7h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/212:48 pm -
1 stop5h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/17:20 pm -
2 stops13h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$344
This Expedia deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/23:08 pm -
2 stops30h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Alaska Airlines logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/26:06 am -
3 stops35h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$1,065
Find flight deals from Medford to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $344 (United Airlines) |
One-way from | $283 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from Medford to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedfordDes Moines
MFR Medford - DSM Des Moines
MFRDSM
Medford
Mon 11/2
8:41 pm-2:38 pm
3 stops39h 57m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$283
MedfordDes Moines
MFR Medford - DSM Des Moines
MFRDSM
Medford
Mon 11/2
5:04 am-2:11 pm
1 stop7h 07m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$329
MedfordDes Moines
MFR Medford - DSM Des Moines
MFRDSM
Medford
Fri 1/1
1:30 pm-11:38 pm
1 stop8h 08m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$329
Quickest round-trip
MedfordDes Moines
MFR Medford - DSM Des Moines
MFRDSM
Medford
Sat 1/2
12:48 pm-8:25 pm
1 stop5h 37m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$339
MedfordDes Moines
MFR Medford - DSM Des Moines
MFRDSM
Medford
Fri 10/23
6:28 pm-10:31 am
2 stops14h 03m
Des Moines
Fri 10/30
5:12 pm-9:18 pm
1 stop6h 06m
$364
MedfordDes Moines
MFR Medford - DSM Des Moines
MFRDSM
Medford
Thu 10/15
6:11 am-9:00 pm
2 stops12h 49m
Des Moines
Tue 10/20
3:46 pm-11:18 pm
2 stops9h 32m
$400
MedfordDes Moines
MFR Medford - DSM Des Moines
MFRDSM
Medford
Mon 10/12
12:20 pm-10:42 am
2 stops20h 22m
Des Moines
Sat 10/17
4:01 pm-11:18 pm
2 stops9h 17m
$400
MedfordDes Moines
MFR Medford - DSM Des Moines
MFRDSM
Medford
Wed 10/14
5:00 am-12:31 pm
1 stop5h 31m
Des Moines
Sat 10/17
5:22 pm-9:14 pm
1 stop5h 52m
$429
MedfordDes Moines
MFR Medford - DSM Des Moines
MFRDSM
Medford
Sat 1/23
6:00 am-8:32 pm
2 stops12h 32m
Des Moines
Wed 1/27
9:37 am-7:55 pm
2 stops12h 18m
$489
MedfordDes Moines
MFR Medford - DSM Des Moines
MFRDSM
Medford
Thu 9/24
1:01 pm-11:35 pm
2 stops8h 34m
Des Moines
Mon 9/28
5:22 pm-9:14 pm
1 stop5h 52m
$523
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Medford to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Medford with our price prediction graph.
MFR-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 11, 2026.
Peruse reviews from past customers who have flown with United Airlines from Medford to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Comfort
7.3
Food
6.7
Overall
7.4
Boarding
7.7
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Entertainment
7.1
Comfort
7.3
Food
6.7
Overall
7.4
Boarding
7.7
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Medford to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Medford and Des Moines flights
Browse other Medford and Des Moines flight options. Last updated on September 11, 2026.
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Top airline flying from Medford to Des Moines
Discover the top airline that operate flights from Medford to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$338 | Average$508 | FlexibilityNo cancel fee | On-time69% |