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Des Moines

$275+ Cheap flights from Medford to Des Moines (MFR - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — DSM
Jul 15 — Jul 221
Wed 7/15
Wed 7/22
1 adult, Economy
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Cheap flight deals from Medford to Des Moines

Cheapest flights from Medford to Des Moines
Explore the most affordable flight options available from Medford to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
-
DSM
1 stop20h 53m
Allegiant Air
Thu 8/139:44 pm
DSM
-
MFR
1 stop19h 04m
Allegiant Air
Deal found 6/14$275
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
-
DSM
1 stop20h 53m
Multiple Airlines
Wed 8/122:19 pm
DSM
-
MFR
2 stops32h 29m
Multiple Airlines
Deal found 6/14$337
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
-
DSM
1 stop20h 53m
Multiple Airlines
Thu 8/139:44 pm
DSM
-
MFR
2 stops24h 43m
Multiple Airlines
Deal found 6/14$353
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:27 pm
MFR
-
DSM
1 stop8h 32m
American Airlines
Tue 9/222:17 pm
DSM
-
MFR
1 stop6h 54m
American Airlines
Deal found 6/12$429
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:23 pm
MFR
-
DSM
1 stop8h 25m
American Airlines
Wed 8/122:39 pm
DSM
-
MFR
1 stop6h 41m
American Airlines
Deal found 6/14$469
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:00 am
MFR
-
DSM
1 stop5h 31m
United Airlines
Mon 10/125:22 pm
DSM
-
MFR
1 stop5h 52m
United Airlines
Deal found 6/14$486
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:28 pm
MFR
-
DSM
2 stops14h 50m
Delta
Wed 8/125:56 pm
DSM
-
MFR
2 stops7h 59m
Delta
Deal found 6/14$497
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:35 pm
MFR
-
DSM
2 stops13h 52m
United Airlines
Tue 6/3011:23 am
DSM
-
MFR
2 stops13h 36m
United Airlines
Deal found 6/11$499
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:23 pm
MFR
-
DSM
1 stop8h 25m
American Airlines
Tue 8/112:39 pm
DSM
-
MFR
1 stop6h 41m
American Airlines
Deal found 6/14$519
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:28 pm
MFR
-
DSM
2 stops14h 50m
Delta
Thu 8/132:45 pm
DSM
-
MFR
2 stops10h 38m
Delta
Deal found 6/14$532
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:20 am
MFR
-
DSM
1 stop6h 34m
American Airlines
Wed 8/122:39 pm
DSM
-
MFR
1 stop6h 41m
American Airlines
Deal found 6/14$541

Find flight deals from Medford to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$275
(Kiwi.com)
Provider with most accurate pricing for Medford-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Medford-Des Moines flights.
Search Deals
From Medford to Des Moines
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
Use the filters below to find and compare flights from Medford to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Thu 10/8

5:00 am-12:31 pm

1 stop5h 31m

Des Moines

Mon 10/12

5:22 pm-9:14 pm

1 stop5h 52m

$486

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Thu 8/6

5:28 pm-10:18 am

2 stops14h 50m

Des Moines

Wed 8/12

5:56 pm-11:55 pm

2 stops7h 59m

$497

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Tue 8/4

2:11 pm-4:15 pm

2 stops24h 04m

Des Moines

Tue 8/11

5:21 pm-9:08 pm

1 stop5h 47m

$557

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Sat 7/11

6:00 am-4:15 pm

2 stops8h 15m

Des Moines

Fri 7/17

5:17 pm-9:16 pm

1 stop5h 59m

$564

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Wed 8/5

6:00 am-4:15 pm

2 stops8h 15m

Des Moines

Wed 8/12

5:45 am-11:54 am

2 stops8h 09m

$572

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Tue 7/7

5:00 am-12:47 pm

1 stop5h 47m

Des Moines

Thu 7/16

5:50 am-12:04 pm

2 stops8h 14m

$584
Quickest round-trip

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Mon 7/27

1:10 pm-8:30 pm

1 stop5h 20m

Des Moines

Tue 8/4

5:17 pm-9:16 pm

1 stop5h 59m

$646

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Sat 7/11

1:23 pm-11:48 pm

1 stop8h 25m

Des Moines

Fri 7/17

5:45 am-12:50 pm

1 stop9h 05m

$651

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/14

Sorted by cheapest first

Compare providers for flights from Medford to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Des Moines in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medford-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medford-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Medford to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 15, 2026.
Peruse reviews from past customers who have flown with United Airlines from Medford to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,831 reviews

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
United Airlines
7.4
Good
9,831 reviews
United Airlines
7.4
Good
9,831 reviews

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

Find useful and relevant information for your journey from Medford to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Medford to Des Moines?

    Departing from Medford to Des Moines will take you 5h 31m. There are 1494 mi between Medford and Des Moines. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Medford to Des Moines round-trip?

    Cheapflights users have booked flights from Medford to Des Moines round-trip from $368.

  • Can I find deals for flights from Medford to Des Moines that include hotel bookings?

    Yes. In addition to deals on Medford to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Des Moines.

  • Can I find deals for business class flights from Medford to Des Moines?

    Yes. Cheapflights offers flight deals from Medford to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Johnston
Clive
Boone
West Des Moines
Ankeny

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