$279+ Cheap flights from Medford to Des Moines (MFR - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — DSM
Aug 8 — Aug 151
Round-trip
1 adult, Economy
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Find cheap flights from Medford to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to Des Moines
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Cheapest flights from Medford to Des MoinesExplore the most affordable flight options available from Medford to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.
Explore the most affordable flight options available from Medford to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
1 stop20h 53m
Allegiant Air
Thu 8/139:44 pm
DSM
- MFR
1 stop19h 04m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
1 stop20h 53m
Multiple Airlines
Wed 8/122:19 pm
DSM
- MFR
2 stops32h 29m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
1 stop20h 53m
Allegiant Air
Sun 8/169:44 pm
DSM
- MFR
1 stop19h 04m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:38 pm
MFR
- DSM
2 stops13h 56m
Multiple Airlines
Sun 8/239:50 pm
DSM
- MFR
1 stop13h 43m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
1 stop20h 53m
Allegiant Air
Sat 8/151:18 pm
DSM
- MFR
2 stops33h 30m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:38 pm
MFR
- DSM
2 stops13h 56m
Multiple Airlines
Thu 8/209:50 pm
DSM
- MFR
1 stop14h 28m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/29:33 pm
MFR
- DSM
1 stop21h 38m
Allegiant Air
Thu 8/139:44 pm
DSM
- MFR
1 stop19h 04m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
2 stops13h 56m
Multiple Airlines
Thu 8/139:44 pm
DSM
- MFR
1 stop19h 04m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
1 stop20h 53m
Multiple Airlines
Sun 8/169:44 pm
DSM
- MFR
2 stops24h 43m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/29:33 pm
MFR
- DSM
1 stop21h 38m
Multiple Airlines
Wed 8/122:19 pm
DSM
- MFR
2 stops32h 29m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$364
Best flights from Medford to Des MoinesDiscover carefully curated flight deals from Medford to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 9, 2026.
Discover carefully curated flight deals from Medford to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 9, 2026.
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
MFR
- DSM
2 stops12h 30m
United Airlines
Sat 7/255:17 pm
DSM
- MFR
1 stop5h 52m
United Airlines
Deal found 7/6![United Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:10 am
MFR
- DSM
1 stop5h 20m
United Airlines
Wed 11/45:11 pm
DSM
- MFR
1 stop6h 11m
United Airlines
Deal found 7/7![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am
MFR
- DSM
2 stops8h 20m
United Airlines
Wed 9/305:45 am
DSM
- MFR
2 stops8h 17m
United Airlines
Deal found 7/4![United Airlines logo]()
$429
Last-minute flights from Medford to Des MoinesDiscover last-minute flight deals from Medford to Des Moines. Data last updated July 9, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to Des Moines. Data last updated July 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/29:33 pm
MFR
- DSM
1 stop21h 38m
Allegiant Air
Thu 8/139:44 pm
DSM
- MFR
1 stop19h 04m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/29:33 pm
MFR
- DSM
1 stop21h 38m
Multiple Airlines
Wed 8/122:19 pm
DSM
- MFR
2 stops32h 29m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
1 stop20h 53m
Allegiant Air
Thu 8/139:44 pm
DSM
- MFR
1 stop19h 04m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
1 stop20h 53m
Multiple Airlines
Wed 8/122:19 pm
DSM
- MFR
2 stops32h 29m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
1 stop20h 53m
Allegiant Air
Sun 8/169:44 pm
DSM
- MFR
1 stop19h 04m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
1 stop20h 53m
Allegiant Air
Sat 8/151:18 pm
DSM
- MFR
2 stops33h 30m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
2 stops13h 56m
Multiple Airlines
Thu 8/139:44 pm
DSM
- MFR
1 stop19h 04m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:38 pm
MFR
- DSM
1 stop20h 53m
Multiple Airlines
Sun 8/169:44 pm
DSM
- MFR
2 stops24h 43m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:38 pm
MFR
- DSM
2 stops13h 56m
Multiple Airlines
Sun 8/239:50 pm
DSM
- MFR
1 stop13h 43m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:38 pm
MFR
- DSM
2 stops13h 56m
Multiple Airlines
Thu 8/209:50 pm
DSM
- MFR
1 stop14h 28m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$343
One-way flights from Medford to Des MoinesSearch for one-way flight options from Medford to Des Moines. Find affordable one-way fares based on user searches. Data last updated July 9, 2026.
Search for one-way flight options from Medford to Des Moines. Find affordable one-way fares based on user searches. Data last updated July 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/209:11 pm
MFR
- DSM
3 stops58h 56m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:15 am
MFR
- DSM
1 stop6h 30m
American Airlines
Deal found 7/6![American Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:35 pm
MFR
- DSM
2 stops13h 42m
United Airlines
Deal found 7/6![United Airlines logo]()
$429
Find flight deals from Medford to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $279 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
Use the filters below to find and compare flights from Medford to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedfordDes Moines
MFR - DSM
MFRDSM
Medford
Tue 7/21
6:00 am-8:30 pm
2 stops12h 30m
Des Moines
Sat 7/25
5:17 pm-9:09 pm
1 stop5h 52m
$404
Quickest round-trip
MedfordDes Moines
MFR - DSM
MFRDSM
Medford
Sat 10/31
5:10 am-12:30 pm
1 stop5h 20m
Des Moines
Wed 11/4
5:11 pm-9:22 pm
1 stop6h 11m
$419
MedfordDes Moines
MFR - DSM
MFRDSM
Medford
Sat 9/26
6:00 am-4:20 pm
2 stops8h 20m
Des Moines
Wed 9/30
5:45 am-12:02 pm
2 stops8h 17m
$429
Cheapest one-way
Quickest one-way
MedfordDes Moines
MFR - DSM
MFRDSM
Medford
Mon 7/20
5:15 am-1:45 pm
1 stop6h 30m
$424
MedfordDes Moines
MFR - DSM
MFRDSM
Medford
Mon 7/20
6:35 pm-10:17 am
2 stops13h 42m
$429
Sorted by cheapest first
Compare providers for flights from Medford to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Des Moines in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Medford with our price prediction graph.
MFR-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated July 9, 2026.
Peruse reviews from past customers who have flown with United Airlines from Medford to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Comfort
7.3
Overall
7.4
Entertainment
7.1
Food
6.7
Crew
8.1
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Boarding
7.7
Comfort
7.3
Overall
7.4
Entertainment
7.1
Food
6.7
Crew
8.1
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Related info for your journey
Find useful and relevant information for your journey from Medford to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 9, 2026.
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Medford and Des Moines flights
Browse other Medford and Des Moines flight options. Last updated on July 9, 2026.
Other flights from Medford
Browse through other flights departing from Medford. Flights are based on user searches made on Cheapflights and were last updated on July 9, 2026.
Popular flight searches
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Top airline flying from Medford to Des Moines
Discover the top airline that operate flights from Medford to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$368 | Average$467 | FlexibilityNo cancel fee | On-time69% |