HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$244+ Cheap flights from Medford to Des Moines (MFR - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/17. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — DSM
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Medford to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Medford to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$689
(United Airlines)

One-way from

$244
(United Airlines)

Popular in

September

Cheapest in

January

Average price

$533
From Medford to Des Moines
Search Deals
One-way flight from Medford to Des Moines
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($156 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($58 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Medford to Des Moines

Cheapest flights from Medford to Des Moines
Explore the most affordable flight options available from Medford to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/154:11 pmMFR - DSM
1 stop28h 23mMultiple Airlines
Wed 6/187:30 amDSM - MFR
2 stops39h 36mMultiple Airlines
Deal found 6/11$606
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/252:12 pmMFR - DSM
3 stops18h 17mUnited Airlines
Sun 6/295:12 pmDSM - MFR
1 stop6h 14mUnited Airlines
Deal found 6/10$689
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/181:34 pmMFR - DSM
1 stop8h 25mAmerican Airlines
Sun 6/225:10 amDSM - MFR
1 stop9h 50mAmerican Airlines
Deal found 6/10$919

Cheapflights Fare Finder

Customize your flight search to find flights from Medford to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Medford to Des Moines that are best for you.

Fly from

Medford

Fly to

Des Moines

Route

Depart

Return

Price

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Sun 6/15

4:11 pm-10:34 pm

1 stop28h 23m

Des Moines

Wed 6/18

7:30 am-9:06 pm

2 stops39h 36m

$606

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Wed 6/25

2:12 pm-10:29 am

3 stops18h 17m

Des Moines

Sun 6/29

5:12 pm-9:26 pm

1 stop6h 14m

$689

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Wed 6/18

1:34 pm-11:59 pm

1 stop8h 25m

Des Moines

Sun 6/22

5:10 am-1:00 pm

1 stop9h 50m

$919

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Thu 7/17

6:35 pm-10:29 am

2 stops13h 54m

$244

MedfordDes Moines

MFR - DSM

MFRDSM

Medford

Thu 7/17

5:30 am-1:53 pm

1 stop6h 23m

$295

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Medford to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Des Moines

What is the cheapest month to book a flight from Medford to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Medford to Des Moines (average of $336). Flying from Medford to Des Moines in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 12, 2025.
United Airlines
7.4
Good
8,790 reviews

Entertainment

7.0

Overall

7.4

Boarding

7.7

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,790 reviews
United Airlines
7.4
Good
8,790 reviews

Entertainment

7.0

Overall

7.4

Boarding

7.7

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,790 reviews

Entertainment

7.0

Overall

7.4

Boarding

7.7

Food

6.6

Crew

8.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Medford to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Medford to Des Moines round-trip?

    Cheapflights users have booked flights from Medford to Des Moines round-trip from $689.

  • Can I find deals for flights from Medford to Des Moines that include hotel bookings?

    Yes. In addition to deals on Medford to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Des Moines.

  • Can I find deals for business class flights from Medford to Des Moines?

    Yes. Cheapflights offers flight deals from Medford to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Medford to Des Moines (average of $336). Flying from Medford to Des Moines in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Medford to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
Portland to Omaha flights
Boise to Omaha flights
Portland to Des Moines flights
Redmond to Omaha flights
Portland to Cedar Rapids flights
Boise to Des Moines flights
Portland to Moline flights
Eugene to Omaha flights
Medford to Cedar Rapids flights
Boise to Cedar Rapids flights
Medford to Omaha flights
Eugene to Cedar Rapids flights
Eugene to Des Moines flights
Portland to Sioux City flights
Portland to La Crosse flights
Portland to Dubuque flights
Boise to La Crosse flights
Portland to Waterloo flights
Boise to Moline flights
Redmond to Cedar Rapids flights
Redmond to Des Moines flights
Yakima to Sioux City flights
Redmond to La Crosse flights
Eugene to Dubuque flights
Boise to Waterloo flights
Eugene to Moline flights
Boise to Sioux City flights

Top 2 airlines flying from Medford to Des Moines

Discover the top 2 airlines that operate flights from Medford to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$268Average$398FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$275Average$501FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.