HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$184+ Cheap flights from Greensboro to Des Moines (GSO - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
GSO — DSM
Apr 12 — Apr 191
Sun 4/12
Sun 4/19
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greensboro to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Greensboro to Des Moines

Cheapest flights from Greensboro to Des Moines
Explore the most affordable flight options available from Greensboro to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.

This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:30 am
GSO
-
DSM
1 stop6h 48m
American Airlines
Sat 5/305:00 am
DSM
-
GSO
1 stop6h 48m
American Airlines
Deal found 3/9$289
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:33 pm
GSO
-
DSM
1 stop6h 37m
American Airlines
Sat 5/305:00 am
DSM
-
GSO
1 stop6h 48m
American Airlines
Deal found 3/9$309
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:30 am
GSO
-
DSM
1 stop4h 57m
United Airlines
Tue 6/911:23 am
DSM
-
GSO
2 stops11h 21m
United Airlines
Deal found 3/8$316
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:00 pm
GSO
-
DSM
1 stop7h 42m
American Airlines
Mon 3/303:26 pm
DSM
-
GSO
1 stop7h 32m
American Airlines
Deal found 3/11$319
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:32 pm
GSO
-
DSM
1 stop5h 26m
American Airlines
Sat 5/301:48 pm
DSM
-
GSO
2 stops7h 23m
American Airlines
Deal found 3/10$334
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:40 am
GSO
-
DSM
1 stop5h 28m
Delta
Mon 5/256:41 pm
DSM
-
GSO
1 stop4h 16m
Delta
Deal found 3/11$339
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:15 am
GSO
-
DSM
1 stop4h 04m
Delta
Mon 7/62:15 pm
DSM
-
GSO
1 stop6h 45m
Delta
Deal found 3/11$344
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:32 pm
GSO
-
DSM
1 stop5h 08m
United Airlines
Fri 5/2911:23 am
DSM
-
GSO
2 stops11h 21m
United Airlines
Deal found 3/9$349

Find flight deals from Greensboro to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Greensboro (GSO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$289
(American Airlines)

One-way from

$184
(American Airlines)

Popular in

January

Cheapest in

August
Provider with most accurate pricing for Greensboro/H. Point-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greensboro/H. Point-Des Moines flights.
Search Deals
From Greensboro/H. Point to Des Moines
Search Deals
One-way flight from Greensboro/H. Point to Des Moines
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($93 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greensboro to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Greensboro to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 5/21

6:40 am-11:08 am

1 stop5h 28m

Des Moines

Sat 5/30

6:41 pm-11:57 pm

1 stop4h 16m

$309

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 4/9

4:48 pm-11:59 pm

1 stop8h 11m

Des Moines

Mon 4/13

5:01 pm-10:31 pm

1 stop4h 30m

$309
Quickest round-trip

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Sun 5/24

6:10 am-9:46 am

1 stop4h 36m

Des Moines

Sat 5/30

6:41 pm-11:57 pm

1 stop4h 16m

$309

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Tue 5/26

6:30 am-10:27 am

1 stop4h 57m

Des Moines

Tue 6/9

11:23 am-11:44 pm

2 stops11h 21m

$316

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 5/21

6:40 am-11:08 am

1 stop5h 28m

Des Moines

Mon 5/25

6:41 pm-11:57 pm

1 stop4h 16m

$339

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Sat 4/11

5:39 pm-11:17 pm

1 stop6h 38m

Des Moines

Tue 4/14

8:20 am-9:02 pm

2 stops11h 42m

$364

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 7/2

7:48 pm-12:29 am

1 stop5h 41m

Des Moines

Mon 7/6

2:41 pm-11:56 pm

2 stops8h 15m

$409
Cheapest one-way

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Wed 4/29

2:00 pm-7:28 pm

1 stop6h 28m

$210

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Tue 4/28

6:35 am-11:05 am

1 stop5h 30m

$219

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Mon 5/18

9:36 pm-12:59 pm

3 stops40h 23m

$232

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/11

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Greensboro to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greensboro to Des Moines in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greensboro-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greensboro-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greensboro-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greensboro-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greensboro-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greensboro to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Greensboro with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greensboro to Des Moines

What is the cheapest month to book a flight from Greensboro to Des Moines?

Currently, May is the cheapest month in which you can book a flight from Greensboro to Des Moines (average of $209). Flying from Greensboro to Des Moines in February is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated March 13, 2026.
See what other customers who have flown with Delta and American Airlines from Greensboro to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,287 reviews

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,287 reviews
Delta
7.9
Good
8,287 reviews

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,448 reviews
Delta
7.9
Good
8,287 reviews

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greensboro to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greensboro to Des Moines?

    For as low as $309, Delta can have you in Des Moines from Greensboro in 5h 28m. The distance between Greensboro and Des Moines is about 827 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Greensboro to Des Moines round-trip?

    American Airlines, at $242, was found to be the cheapest airline from Greensboro to Des Moines. An alternate airline flying to your destination would be Delta. You may be able to fly from Greensboro to Des Moines for 26% less than the average price by searching for these airlines.

  • Can I find deals for flights from Greensboro to Des Moines that include hotel bookings?

    Yes. In addition to deals on Greensboro to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greensboro to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greensboro to Des Moines.

  • Can I find deals for business class flights from Greensboro to Des Moines?

    Yes. Cheapflights offers flight deals from Greensboro to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greensboro to Des Moines?

    Currently, May is the cheapest month in which you can book a flight from Greensboro to Des Moines (average of $209). Flying from Greensboro to Des Moines in February is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Greensboro to Des Moines

Discover the top 2 airlines that operate flights from Greensboro to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$242Average$323FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$289FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
Cookie settings©2026 Cheapflights