$106+ Cheap flights from Clearwater, FL to Des Moines (DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
MCO — DSM
Aug 4 — Aug 111
Round-trip
1 adult, Economy
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Find cheap flights from Clearwater to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Clearwater to Des Moines
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Best
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Cheapest flights from Clearwater to Des MoinesExplore the most affordable flight options available from Clearwater to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 5, 2026.
Explore the most affordable flight options available from Clearwater to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 5, 2026.
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:15 am
TPA
- DSM
1 stop6h 41m
American Airlines
Wed 7/291:41 pm
DSM
- TPA
1 stop7h 18m
American Airlines
Deal found 7/1![American Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:55 am
TPA
- DSM
1 stop5h 35m
Southwest
Tue 8/42:40 pm
DSM
- TPA
2 stops6h 15m
Southwest
Deal found 6/30![Southwest logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:00 am
TPA
- DSM
2 stops17h 07m
Multiple Airlines
Mon 7/274:40 pm
DSM
- TPA
1 stop14h 28m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/294:51 pm
TPA
- DSM
1 stop8h 18m
American Airlines
Wed 8/55:10 pm
DSM
- TPA
1 stop5h 11m
American Airlines
Deal found 7/1![American Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:30 pm
TPA
- DSM
1 stop23h 57m
Multiple Airlines
Mon 8/34:40 pm
DSM
- TPA
1 stop14h 28m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:36 pm
TPA
- DSM
1 stop6h 33m
Delta
Mon 11/93:30 pm
DSM
- TPA
1 stop6h 04m
Delta
Deal found 7/3![Delta logo]()
$288
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:15 am
TPA
- DSM
1 stop7h 10m
Southwest
Wed 10/75:35 am
DSM
- TPA
2 stops7h 05m
Southwest
Deal found 7/2![Southwest logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:30 pm
TPA
- DSM
1 stop24h 01m
Multiple Airlines
Sun 8/165:12 pm
DSM
- TPA
2 stops13h 11m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:00 am
TPA
- DSM
2 stops17h 07m
Multiple Airlines
Thu 7/303:37 pm
DSM
- TPA
1 stop28h 48m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$303
Best flights from Clearwater to Des MoinesDiscover carefully curated flight deals from Clearwater to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 5, 2026.
Discover carefully curated flight deals from Clearwater to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 5, 2026.
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:55 am
TPA
- DSM
1 stop5h 35m
Southwest
Tue 8/42:40 pm
DSM
- TPA
2 stops6h 15m
Southwest
Deal found 6/30![Southwest logo]()
$242
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:16 pm
TPA
- DSM
1 stop5h 40m
Delta
Mon 11/96:30 pm
DSM
- TPA
1 stop4h 50m
Delta
Deal found 7/2![Delta logo]()
$288
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:00 am
TPA
- DSM
2 stops9h 18m
United Airlines
Wed 8/266:00 am
DSM
- TPA
2 stops8h 28m
United Airlines
Deal found 7/2![United Airlines logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/304:46 pm
TPA
- DSM
2 stops27h 18m
Multiple Airlines
Mon 8/34:40 pm
DSM
- TPA
1 stop14h 28m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:35 am
TPA
- DSM
1 stop5h 15m
Southwest
Mon 8/245:40 am
DSM
- TPA
2 stops8h 40m
Southwest
Deal found 6/30![Southwest logo]()
$293
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:10 pm
TPA
- DSM
2 stops9h 00m
Southwest
Wed 10/75:35 am
DSM
- TPA
2 stops10h 15m
Southwest
Deal found 6/30![Southwest logo]()
$298
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:35 pm
TPA
- DSM
1 stop5h 27m
United Airlines
Mon 11/96:21 am
DSM
- TPA
2 stops12h 50m
United Airlines
Deal found 7/1![United Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:35 am
TPA
- DSM
1 stop5h 15m
Southwest
Fri 8/75:40 am
DSM
- TPA
2 stops10h 30m
Southwest
Deal found 6/30![Southwest logo]()
$343
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:50 am
TPA
- DSM
1 stop7h 15m
Southwest
Wed 8/56:10 am
DSM
- TPA
2 stops7h 45m
Southwest
Deal found 7/1![Southwest logo]()
$347
Last-minute flights from Clearwater to Des MoinesDiscover last-minute flight deals from Clearwater to Des Moines. Data last updated July 5, 2026 and is based on user searches.
Discover last-minute flight deals from Clearwater to Des Moines. Data last updated July 5, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:00 am
TPA
- DSM
2 stops17h 07m
Multiple Airlines
Thu 7/303:37 pm
DSM
- TPA
1 stop28h 48m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:15 am
TPA
- DSM
1 stop6h 41m
American Airlines
Wed 7/291:41 pm
DSM
- TPA
1 stop7h 18m
American Airlines
Deal found 7/1![American Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:00 am
TPA
- DSM
2 stops17h 07m
Multiple Airlines
Mon 7/274:40 pm
DSM
- TPA
1 stop14h 28m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$268
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:55 am
TPA
- DSM
1 stop5h 35m
Southwest
Tue 8/42:40 pm
DSM
- TPA
2 stops6h 15m
Southwest
Deal found 6/30![Southwest logo]()
$242
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/294:51 pm
TPA
- DSM
1 stop8h 18m
American Airlines
Wed 8/55:10 pm
DSM
- TPA
1 stop5h 11m
American Airlines
Deal found 7/1![American Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:30 pm
TPA
- DSM
1 stop23h 57m
Multiple Airlines
Mon 8/34:40 pm
DSM
- TPA
1 stop14h 28m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
TPA
- DSM
1 stop7h 24m
American Airlines
Wed 8/121:08 pm
DSM
- TPA
1 stop5h 49m
American Airlines
Deal found 7/1![American Airlines logo]()
$288
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:15 am
TPA
- DSM
1 stop7h 10m
Southwest
Wed 8/126:10 am
DSM
- TPA
2 stops9h 55m
Southwest
Deal found 7/1![Southwest logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:30 pm
TPA
- DSM
1 stop24h 01m
Multiple Airlines
Sun 8/165:12 pm
DSM
- TPA
2 stops13h 11m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$302
One-way flights from Clearwater to Des MoinesSearch for one-way flight options from Clearwater to Des Moines. Find affordable one-way fares based on user searches. Data last updated July 5, 2026.
Search for one-way flight options from Clearwater to Des Moines. Find affordable one-way fares based on user searches. Data last updated July 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:30 pm
TPA
- DSM
1 stop23h 57m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:00 am
TPA
- DSM
2 stops17h 19m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:00 am
TPA
- DSM
2 stops17h 19m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$128
This Booking.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:40 pm
TPA
- DSM
1 stop25h 54m
Frontier
Deal found 7/3![Frontier logo]()
$131
This Super.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:20 pm
TPA
- DSM
1 stop18h 14m
Frontier
Deal found 7/3![Frontier logo]()
$137
This Gotogate deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:40 pm
TPA
- DSM
1 stop25h 54m
Frontier
Deal found 7/3![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:55 pm
TPA
- DSM
2 stops26h 52m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$156
This Super.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:20 pm
TPA
- DSM
1 stop18h 14m
Frontier
Deal found 7/3![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:25 pm
TPA
- DSM
2 stops32h 02m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$168
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:15 am
TPA
- DSM
1 stop7h 10m
Southwest
Deal found 7/2![Southwest logo]()
$170
Find flight deals from Clearwater to Des Moines
Keep the following information in mind while searching for Clearwater to Des Moines flight deals. Data was last updated July 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $237 (American Airlines) |
One-way from | $106 (Kiwi.com) |
Popular in | April |
Cheapest in | September |
Average price | $369 |
Cheapflights Fare Finder
Customize your flight search to find flights from Clearwater to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 5, 2026.
Use the filters below to find and compare flights from Clearwater to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
TampaDes Moines
TPA - DSM
TPADSM
Tampa
Tue 7/28
6:55 am-11:30 am
1 stop5h 35m
Des Moines
Tue 8/4
2:40 pm-9:55 pm
2 stops6h 15m
$242
Quickest round-trip
TampaDes Moines
TPA - DSM
TPADSM
Tampa
Wed 11/4
12:16 pm-4:56 pm
1 stop5h 40m
Des Moines
Mon 11/9
6:30 pm-12:20 am
1 stop4h 50m
$288
TampaDes Moines
TPA - DSM
TPADSM
Tampa
Wed 8/19
7:35 am-11:50 am
1 stop5h 15m
Des Moines
Mon 8/24
5:40 am-3:20 pm
2 stops8h 40m
$293
TampaDes Moines
TPA - DSM
TPADSM
Tampa
Thu 9/24
2:10 pm-10:10 pm
2 stops9h 00m
Des Moines
Wed 10/7
5:35 am-4:50 pm
2 stops10h 15m
$298
TampaDes Moines
TPA - DSM
TPADSM
Tampa
Tue 8/25
9:00 am-5:18 pm
2 stops9h 18m
Des Moines
Wed 8/26
6:00 am-3:28 pm
2 stops8h 28m
$337
TampaDes Moines
TPA - DSM
TPADSM
Tampa
Wed 8/5
7:35 am-11:50 am
1 stop5h 15m
Des Moines
Fri 8/7
5:40 am-5:10 pm
2 stops10h 30m
$343
TampaDes Moines
TPA - DSM
TPADSM
Tampa
Thu 7/30
4:46 pm-7:04 pm
2 stops27h 18m
Des Moines
Mon 8/3
4:40 pm-8:08 am
1 stop14h 28m
$347
TampaDes Moines
TPA - DSM
TPADSM
Tampa
Wed 7/29
8:50 am-3:05 pm
1 stop7h 15m
Des Moines
Wed 8/5
6:10 am-2:55 pm
2 stops7h 45m
$347
TampaDes Moines
TPA - DSM
TPADSM
Tampa
Wed 11/4
6:35 pm-11:02 pm
1 stop5h 27m
Des Moines
Mon 11/9
6:21 am-8:11 pm
2 stops12h 50m
$383
Cheapest one-way
TampaDes Moines
TPA - DSM
TPADSM
Tampa
Thu 8/6
7:00 am-11:19 pm
2 stops17h 19m
$127
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Clearwater to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Clearwater with our price prediction graph.
TPA-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Clearwater to Des Moines
CL9-DSM
TPA-DSM
What is the cheapest time of day to fly from CL9 to DSM?
Find hourly flight availability from Clearwater to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 5, 2026.
One of the essential ways to save on airfare from Clearwater to Des Moines is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 35% on airfare.
How much does it cost to fly round-trip from Clearwater to Des Moines?
What is the cheapest day to fly from Clearwater to Des Moines?
Use this chart to determine the cheapest time to fly round-trip from Clearwater to Des Moines. Price data was last updated on August 31, 2025.
Travelers seeking maximum savings on their Clearwater to Des Moines flight should consider departing on Tuesday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated July 5, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Clearwater to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Clearwater to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 5, 2026.
Search flights from Clearwater to Des Moines by cabin class
Find flights from Clearwater to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Clearwater and Des Moines flights
Browse other Clearwater and Des Moines flight options. Last updated on July 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Clearwater to Des Moines flights
Consider these flights traveling from Clearwater to Des Moines.
Top 5 airlines flying from Clearwater to Des Moines
Discover the top 5 airlines that operate flights from Clearwater to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$90 | Average$130 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$136 | Average$242 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$222 | Average$455 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$250 | Average$421 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$497 | Average$530 | FlexibilityNo cancel fee | On-time69% |