$111+ Cheap flights from Chicago (CHI) to Des Moines (DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — DSM
Aug 22 — Aug 291
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Chicago to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Chicago to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Chicago to Des MoinesExplore the most affordable flight options available from Chicago to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
Explore the most affordable flight options available from Chicago to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:00 am
ORD
- DSM
1 stop13h 57m
Multiple Airlines
Thu 9/101:58 pm
DSM
- ORD
1 stop22h 43m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$211
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:26 am
ORD
- DSM
Nonstop1h 30m
American Airlines
Wed 8/267:49 pm
DSM
- ORD
Nonstop1h 48m
American Airlines
Deal found 7/22![American Airlines logo]()
$236
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:54 am
ORD
- DSM
Nonstop1h 31m
American Airlines
Sun 9/66:10 am
DSM
- ORD
Nonstop1h 50m
American Airlines
Deal found 7/19![American Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:30 am
MDW
- DSM
Nonstop1h 20m
Southwest
Thu 8/135:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 7/21![Southwest logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am
ORD
- DSM
1 stop13h 57m
Multiple Airlines
Thu 9/101:58 pm
DSM
- ORD
1 stop22h 43m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am
ORD
- DSM
1 stop13h 54m
Multiple Airlines
Sun 8/301:55 pm
DSM
- ORD
1 stop17h 34m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$252
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:30 am
MDW
- DSM
Nonstop1h 20m
Southwest
Tue 8/257:15 am
DSM
- MDW
2 stops9h 45m
Southwest
Deal found 7/21![Southwest logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:05 am
ORD
- DSM
2 stops16h 14m
Multiple Airlines
Mon 8/1712:37 pm
DSM
- ORD
1 stop27h 22m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Tue 9/86:10 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 7/19![Southwest logo]()
$255
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:28 am
ORD
- DSM
1 stop5h 36m
Delta
Fri 9/116:00 am
DSM
- ORD
1 stop6h 59m
Delta
Deal found 7/19![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:15 am
MDW
- DSM
2 stops10h 30m
Southwest
Sat 9/125:30 am
DSM
- MDW
Nonstop1h 15m
Southwest
Deal found 7/22![Southwest logo]()
$258
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:50 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Thu 9/102:25 pm
DSM
- MDW
1 stop7h 35m
Southwest
Deal found 7/22![Southwest logo]()
$265
Best flights from Chicago to Des MoinesDiscover carefully curated flight deals from Chicago to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
Discover carefully curated flight deals from Chicago to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:50 pm
ORD
- DSM
Nonstop1h 25m
United Airlines
Sat 10/2411:27 am
DSM
- ORD
Nonstop1h 39m
United Airlines
Deal found 7/22![United Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:30 am
MDW
- DSM
Nonstop1h 20m
Southwest
Thu 8/132:25 pm
DSM
- MDW
1 stop7h 35m
Southwest
Deal found 7/21![Southwest logo]()
$247
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:55 pm
ORD
- DSM
1 stop6h 51m
Delta
Sat 9/196:00 am
DSM
- ORD
1 stop6h 58m
Delta
Deal found 7/22![Delta logo]()
$313
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:00 am
ORD
- DSM
Nonstop1h 26m
United Airlines
Sat 9/1211:32 am
DSM
- ORD
Nonstop1h 43m
United Airlines
Deal found 7/22![United Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:05 pm
MDW
- DSM
2 stops7h 30m
Southwest
Sat 10/247:00 am
DSM
- MDW
1 stop7h 20m
Southwest
Deal found 7/22![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:25 pm
MDW
- DSM
1 stop3h 46m
Delta
Sun 8/306:55 am
DSM
- MDW
1 stop6h 15m
Delta
Deal found 7/20![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/222:05 pm
MDW
- DSM
1 stop6h 40m
Southwest
Sun 8/235:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 7/21![Southwest logo]()
$293
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:55 pm
ORD
- DSM
Nonstop1h 28m
United Airlines
Sun 8/303:20 pm
DSM
- ORD
Nonstop1h 43m
United Airlines
Deal found 7/20![United Airlines logo]()
$301
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:59 am
MDW
- DSM
1 stop4h 05m
Delta
Wed 9/97:00 am
DSM
- MDW
1 stop6h 20m
Delta
Deal found 7/19![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:05 pm
MDW
- DSM
1 stop7h 10m
Southwest
Sun 8/305:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 7/21![Southwest logo]()
$293
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:50 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Thu 8/203:50 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 7/22![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:39 pm
ORD
- DSM
1 stop5h 28m
Delta
Sun 10/1810:59 am
DSM
- ORD
1 stop3h 45m
Delta
Deal found 7/22![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:30 pm
ORD
- DSM
Nonstop1h 32m
United Airlines
Mon 11/161:35 pm
DSM
- ORD
2 stops21h 36m
United Airlines
Deal found 7/21![United Airlines logo]()
$376
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:35 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Fri 8/145:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 7/19![Southwest logo]()
$315
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:15 am
MDW
- DSM
Nonstop1h 20m
Southwest
Sun 9/205:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 7/22![Southwest logo]()
$339
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:59 pm
ORD
- DSM
1 stop6h 40m
Delta
Sat 8/1510:59 am
DSM
- ORD
2 stops9h 31m
Delta
Deal found 7/20![Delta logo]()
$420
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:50 pm
ORD
- DSM
Nonstop1h 25m
United Airlines
Tue 10/66:00 am
DSM
- ORD
1 stop18h 23m
United Airlines
Deal found 7/18![United Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:55 pm
ORD
- DSM
1 stop6h 51m
Delta
Tue 9/1510:59 am
DSM
- ORD
2 stops9h 31m
Delta
Deal found 7/21![Delta logo]()
$430
Last-minute flights from Chicago to Des MoinesDiscover last-minute flight deals from Chicago to Des Moines. Data last updated July 23, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Des Moines. Data last updated July 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:45 pm
ORD
- DSM
Nonstop1h 35m
American Airlines
Mon 8/247:49 pm
DSM
- ORD
Nonstop1h 48m
American Airlines
Deal found 7/18![American Airlines logo]()
$272
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:05 am
MDW
- DSM
Nonstop1h 20m
Southwest
Mon 8/243:50 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 7/18![Southwest logo]()
$273
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:30 am
MDW
- DSM
Nonstop1h 20m
Southwest
Thu 8/135:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 7/21![Southwest logo]()
$237
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:26 am
ORD
- DSM
Nonstop1h 30m
American Airlines
Sat 8/151:55 pm
DSM
- ORD
Nonstop1h 46m
American Airlines
Deal found 7/20![American Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:26 am
ORD
- DSM
Nonstop1h 30m
American Airlines
Mon 8/177:49 pm
DSM
- ORD
Nonstop1h 48m
American Airlines
Deal found 7/22![American Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:05 am
ORD
- DSM
2 stops16h 14m
Multiple Airlines
Mon 8/1712:37 pm
DSM
- ORD
1 stop27h 22m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Tue 8/187:15 am
DSM
- MDW
2 stops9h 45m
Southwest
Deal found 7/19![Southwest logo]()
$288
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:30 am
MDW
- DSM
Nonstop1h 20m
Southwest
Tue 8/257:15 am
DSM
- MDW
2 stops9h 45m
Southwest
Deal found 7/21![Southwest logo]()
$252
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:26 am
ORD
- DSM
Nonstop1h 30m
American Airlines
Wed 8/267:49 pm
DSM
- ORD
Nonstop1h 48m
American Airlines
Deal found 7/22![American Airlines logo]()
$236
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
ORD
- DSM
1 stop4h 18m
Delta
Wed 8/2610:23 am
DSM
- ORD
1 stop5h 54m
Delta
Deal found 7/22![Delta logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
ORD
- DSM
1 stop13h 54m
Multiple Airlines
Sun 8/231:55 pm
DSM
- ORD
1 stop17h 34m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am
ORD
- DSM
1 stop13h 54m
Multiple Airlines
Sun 8/301:55 pm
DSM
- ORD
1 stop17h 34m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$252
One-way flights from Chicago to Des MoinesSearch for one-way flight options from Chicago to Des Moines. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
Search for one-way flight options from Chicago to Des Moines. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:50 am
ORD
- DSM
1 stop13h 07m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:33 pm
ORD
- DSM
2 stops17h 09m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:50 am
ORD
- DSM
1 stop7h 52m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$116
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:30 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 7/22![Southwest logo]()
$119
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/191:35 pm
ORD
- DSM
1 stop7h 17m
Delta
Deal found 7/22![Delta logo]()
$129
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:28 am
ORD
- DSM
1 stop5h 36m
Delta
Deal found 7/22![Delta logo]()
$134
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:25 pm
MDW
- DSM
1 stop3h 53m
Delta
Deal found 7/22![Delta logo]()
$134
This Trip.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2010:40 pm
ORD
- DSM
1 stop15h 16m
Frontier
Deal found 7/21![Frontier logo]()
$136
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:45 pm
ORD
- DSM
Nonstop1h 35m
American Airlines
Deal found 7/19![American Airlines logo]()
$137
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:30 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 7/19![Southwest logo]()
$137
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:15 am
ORD
- DSM
Nonstop1h 39m
American Airlines
Deal found 7/19![American Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:03 pm
ORD
- DSM
2 stops22h 36m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$141
Find flight deals from Chicago to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $211 (Kiwi.com) |
One-way from | $111 (Kiwi.com) |
Popular in | August |
Cheapest in | October |
Average price | $459 |
Good round-trip deal | $379 or less |
Good one-way deal | $143 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from Chicago to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Tue 10/20
12:50 pm-2:15 pm
Nonstop1h 25m
Des Moines
Sat 10/24
11:27 am-1:06 pm
Nonstop1h 39m
$237
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Tue 9/1
9:00 am-10:26 am
Nonstop1h 26m
Des Moines
Sat 9/12
11:32 am-1:15 pm
Nonstop1h 43m
$237
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Tue 8/11
10:30 am-11:50 am
Nonstop1h 20m
Des Moines
Thu 8/13
2:25 pm-10:00 pm
1 stop7h 35m
$247
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Tue 10/20
1:05 pm-8:35 pm
2 stops7h 30m
Des Moines
Sat 10/24
7:00 am-2:20 pm
1 stop7h 20m
$262
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Sat 8/22
2:05 pm-8:45 pm
1 stop6h 40m
Des Moines
Sun 8/23
5:40 am-7:00 am
Nonstop1h 20m
$293
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Thu 8/27
2:05 pm-9:15 pm
1 stop7h 10m
Des Moines
Sun 8/30
5:40 am-7:00 am
Nonstop1h 20m
$293
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Thu 8/27
7:55 pm-9:23 pm
Nonstop1h 28m
Des Moines
Sun 8/30
3:20 pm-5:03 pm
Nonstop1h 43m
$301
Quickest round-trip
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Mon 8/17
8:50 pm-10:10 pm
Nonstop1h 20m
Des Moines
Thu 8/20
3:50 pm-5:10 pm
Nonstop1h 20m
$307
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Fri 9/18
1:55 pm-8:46 pm
1 stop6h 51m
Des Moines
Sat 9/19
6:00 am-12:58 pm
1 stop6h 58m
$313
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Wed 8/12
8:35 pm-9:55 pm
Nonstop1h 20m
Des Moines
Fri 8/14
5:40 am-7:00 am
Nonstop1h 20m
$315
Showing 1-10 of 40 resultsSorted by cheapest first
Compare providers for flights from Chicago to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Des Moines in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Chicago with our price prediction graph.
CHI-DSM
ORD-DSM
MDW-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Des Moines
CHI-DSM
ORD-DSM
MDW-DSM
What is the cheapest month to book a flight from Chicago to Des Moines?
Currently, October is the cheapest month in which you can book a flight from Chicago to Des Moines (average of $242). Flying from Chicago to Des Moines in June is currently the most expensive (average of $499). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to DSM?
Find hourly flight availability from Chicago to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 23, 2026.
It’s optimal to fly from Chicago to Des Moines at noon. By choosing this option you can save up to 51% on the cost of your flight, compared to a flight in the afternoon.
Weekly flight availability from Chicago to Des Moines
Explore weekly flight availability from Chicago to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 23, 2026.
The most flights from CHI to DSM are scheduled on a Monday (49 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (11 on average).
How much does it cost to fly round-trip from Chicago to Des Moines?
What is the cheapest day to fly from Chicago to Des Moines?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Des Moines. Price data was last updated on July 18, 2026.
Travelers seeking maximum savings on their Chicago to Des Moines flight should consider departing on Thursday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated July 23, 2026.
See what other customers who have flown with United Airlines and American Airlines from Chicago to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Overall
7.4
Crew
8.1
Boarding
7.7
Comfort
7.3
Food
6.6
Reviews
1 / 20
10.0
ExcellentTim,May 2023
ORD - DLH
Entertainment
7.1
Overall
7.4
Crew
8.1
Boarding
7.7
Comfort
7.3
Food
6.6
Reviews
1 / 20
10.0
ExcellentTim,May 2023
ORD - DLH
Entertainment
7.1
Overall
7.4
Crew
8.1
Boarding
7.7
Comfort
7.3
Food
6.6
Reviews
1 / 20
10.0
ExcellentTim,May 2023
ORD - DLH
Related info for your journey
Find useful and relevant information for your journey from Chicago to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Other flights from Chicago
Popular flights
Alternative routes for Chicago to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 23, 2026.
Search flights from Chicago to Des Moines by cabin class
Find flights from Chicago to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Des Moines flights
Browse other Chicago and Des Moines flight options. Last updated on July 23, 2026.
Other flights from Chicago
Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on July 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Chicago to Des Moines
Discover the top 3 airlines that operate flights from Chicago to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$189 | Average$334 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$425 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$209 | Average$419 | FlexibilityNo cancel fee | On-time63% |