$119+ Cheap flights from Chicago (CHI) to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — DSM
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to Des MoinesExplore the most affordable flight options available from Chicago to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Chicago to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:50 pm -
Nonstop1h 25m
Tue 10/279:50 am -
Nonstop1h 39m
Deal found 9/9![United Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:40 am -
Nonstop1h 20m
Mon 10/55:10 am -
Nonstop1h 20m
Deal found 9/7![Southwest logo]()
$237
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:17 am -
Nonstop1h 39m
Mon 10/127:31 pm -
Nonstop1h 38m
Deal found 9/8![American Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:25 pm -
Nonstop1h 25m
Mon 10/194:30 pm -
Nonstop1h 20m
Deal found 9/7![Southwest logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:04 am -
1 stop8h 48m
Thu 10/298:43 am -
1 stop14h 00m
Deal found 9/9![Multiple Airlines logo]()
$252
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:05 pm -
2 stops7h 35m
Wed 10/283:00 pm -
Nonstop1h 20m
Deal found 9/8![Southwest logo]()
$252
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:10 am -
1 stop4h 07m
Tue 10/63:46 pm -
1 stop5h 41m
Deal found 9/9![Delta logo]()
$257
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:59 am -
1 stop4h 07m
Tue 10/610:57 am -
1 stop5h 50m
Deal found 9/8![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:50 pm -
Nonstop1h 25m
Tue 10/137:05 am -
2 stops9h 00m
Deal found 9/8![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:20 am -
1 stop4h 01m
Mon 12/74:53 pm -
1 stop4h 42m
Deal found 9/7![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:45 am -
Nonstop1h 25m
Mon 10/54:30 pm -
Nonstop1h 20m
Deal found 9/9![Southwest logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:25 am -
1 stop6h 45m
Mon 10/58:30 pm -
1 stop27h 53m
Deal found 9/9![Multiple Airlines logo]()
$279
Best flights from Chicago to Des MoinesDiscover carefully curated flight deals from Chicago to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Chicago to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:00 am -
Nonstop1h 31m
Mon 10/196:55 pm -
Nonstop1h 38m
Deal found 9/8![United Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:50 pm -
Nonstop1h 25m
Mon 10/197:10 pm -
1 stop5h 10m
Deal found 9/8![Southwest logo]()
$257
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:17 am -
Nonstop1h 39m
Sun 10/117:31 pm -
Nonstop1h 38m
Deal found 9/4![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:42 pm -
1 stop3h 31m
Fri 11/132:48 pm -
1 stop4h 51m
Deal found 9/6![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:00 pm -
Nonstop1h 35m
Thu 10/151:24 pm -
Nonstop1h 36m
Deal found 9/7![United Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:35 pm -
1 stop7h 25m
Fri 11/135:25 am -
Nonstop1h 30m
Deal found 9/6![Southwest logo]()
$319
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:29 pm -
1 stop3h 44m
Wed 11/116:45 am -
1 stop5h 05m
Deal found 9/6![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:50 pm -
1 stop5h 20m
Tue 10/135:35 am -
Nonstop1h 20m
Deal found 9/8![Southwest logo]()
$322
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:05 am -
Nonstop1h 25m
Tue 10/277:05 am -
2 stops9h 00m
Deal found 9/5![Southwest logo]()
$324
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:10 am -
1 stop4h 07m
Sun 9/272:46 pm -
1 stop4h 47m
Deal found 9/5![Delta logo]()
$388
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:50 pm -
Nonstop1h 20m
Sun 10/45:30 am -
Nonstop1h 20m
Deal found 9/6![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:50 pm -
1 stop5h 20m
Mon 10/127:10 pm -
1 stop5h 10m
Deal found 9/5![Southwest logo]()
$354
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:20 am -
1 stop3h 51m
Wed 10/1410:57 am -
1 stop3h 39m
Deal found 9/8![Delta logo]()
$430
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:54 pm -
Nonstop1h 26m
Fri 9/253:11 pm -
Nonstop1h 43m
Deal found 9/6![United Airlines logo]()
$537
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:05 am -
1 stop7h 15m
Mon 10/57:10 pm -
1 stop5h 10m
Deal found 9/6![Southwest logo]()
$368
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/304:20 pm -
Nonstop1h 28m
Tue 10/65:45 am -
1 stop13h 45m
Deal found 9/4![United Airlines logo]()
$549
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:55 am -
2 stops7h 53m
Tue 10/63:46 pm -
1 stop5h 41m
Deal found 9/4![Delta logo]()
$524
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:20 pm -
Nonstop1h 28m
Mon 10/121:27 pm -
1 stop9h 19m
Deal found 9/5![United Airlines logo]()
$560
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:25 pm -
Nonstop1h 30m
Thu 11/129:00 am -
1 stop12h 30m
Deal found 9/6![United Airlines logo]()
$560
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:00 pm -
1 stop18h 21m
Sun 10/46:55 pm -
Nonstop1h 38m
Deal found 9/8![United Airlines logo]()
$566
Last-minute flights from Chicago to Des MoinesDiscover last-minute flight deals from Chicago to Des Moines. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Des Moines. Data last updated September 9, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:10 am -
1 stop4h 07m
Tue 10/63:46 pm -
1 stop5h 41m
Deal found 9/9![Delta logo]()
$257
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:59 am -
1 stop4h 07m
Tue 10/610:57 am -
1 stop5h 50m
Deal found 9/8![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:45 am -
Nonstop1h 25m
Mon 10/54:30 pm -
Nonstop1h 20m
Deal found 9/9![Southwest logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:25 am -
1 stop6h 45m
Mon 10/58:30 pm -
1 stop27h 53m
Deal found 9/9![Multiple Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:40 am -
Nonstop1h 20m
Mon 10/55:10 am -
Nonstop1h 20m
Deal found 9/7![Southwest logo]()
$237
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:55 am -
2 stops6h 25m
Wed 10/143:00 pm -
Nonstop1h 20m
Deal found 9/8![Southwest logo]()
$288
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:17 am -
Nonstop1h 39m
Mon 10/127:31 pm -
Nonstop1h 38m
Deal found 9/8![American Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:50 pm -
Nonstop1h 25m
Tue 10/137:05 am -
2 stops9h 00m
Deal found 9/8![Southwest logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:04 am -
1 stop8h 48m
Thu 10/298:43 am -
1 stop14h 00m
Deal found 9/9![Multiple Airlines logo]()
$252
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:50 pm -
Nonstop1h 25m
Tue 10/279:50 am -
Nonstop1h 39m
Deal found 9/9![United Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:25 pm -
Nonstop1h 25m
Mon 10/194:30 pm -
Nonstop1h 20m
Deal found 9/7![Southwest logo]()
$247
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:05 pm -
2 stops7h 35m
Wed 10/283:00 pm -
Nonstop1h 20m
Deal found 9/8![Southwest logo]()
$252
One-way flights from Chicago to Des MoinesSearch for one-way flight options from Chicago to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Chicago to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:00 am -
Nonstop1h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$119
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:35 pm -
Nonstop1h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Southwest logo]()
$119
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/147:30 am -
Nonstop1h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$120
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:10 am -
1 stop4h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$129
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:12 am -
1 stop4h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:11 am -
1 stop25h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$134
This CheapOair deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:30 am -
1 stop13h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Frontier logo]()
$136
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop4h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$139
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:31 pm -
1 stop3h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$139
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:15 am -
2 stops10h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Southwest logo]()
$140
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/139:00 am -
Nonstop1h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![United Airlines logo]()
$148
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:15 am -
2 stops10h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Southwest logo]()
$150
Find flight deals from Chicago to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $236 (American Airlines) |
One-way from | $119 (United Airlines) |
Popular in | August |
Cheapest in | October |
Average price | $299 |
Good round-trip deal | $291 or less |
Good one-way deal | $108 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Chicago to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Wed 10/14
9:00 am-10:31 am
Nonstop1h 31m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$119
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Thu 1/14
12:15 pm-3:57 pm
1 stop3h 42m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Sat 10/10
6:20 am-10:11 am
1 stop3h 51m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Mon 12/7
10:24 am-4:11 pm
1 stop5h 47m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Sat 10/10
10:12 am-2:25 pm
1 stop4h 13m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Wed 10/7
10:12 am-2:25 pm
1 stop4h 13m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Tue 10/6
5:31 pm-9:00 pm
1 stop3h 29m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Tue 12/8
5:30 pm-9:31 pm
1 stop4h 01m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Fri 10/9
5:31 pm-9:00 pm
1 stop3h 29m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$139
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Tue 12/8
10:15 am-8:45 pm
2 stops10h 30m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
Showing 1-10 of 42 resultsSorted by cheapest first
Compare providers for flights from Chicago to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Chicago with our price prediction graph.
CHI-DSM
ORD-DSM
MDW-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Des Moines
CHI-DSM
ORD-DSM
MDW-DSM
What is the cheapest month to book a flight from Chicago to Des Moines?
Currently, October is the cheapest month in which you can book a flight from Chicago to Des Moines (average of $269). Flying from Chicago to Des Moines in August is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to DSM?
Find hourly flight availability from Chicago to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 9, 2026.
It’s optimal to fly from Chicago to Des Moines at noon. By choosing this option you can save up to 52% on the cost of your flight, compared to a flight in the afternoon.
Weekly flight availability from Chicago to Des Moines
Explore weekly flight availability from Chicago to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 9, 2026.
The most flights from CHI to DSM are scheduled on a Tuesday (39 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (7 on average).
How much does it cost to fly round-trip from Chicago to Des Moines?
Airfare is below average for this route at the moment.
Chicago to Des Moines flights typically cost between $273 and $395 in October.The cheapest round-trip price found within the last 5 days was $236 on American Airlines (Oct 24-Oct 31).
What is the cheapest day to fly from Chicago to Des Moines?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Des Moines. Price data was last updated on September 5, 2026.
Travelers seeking maximum savings on their Chicago to Des Moines flight should consider departing on Wednesday evenings when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 9, 2026.
See what other customers who have flown with Southwest,United Airlines, andAmerican Airlines from Chicago to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Chicago to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Other flights to Des Moines
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Chicago and Des Moines flights
Browse other Chicago and Des Moines flight options. Last updated on September 9, 2026.
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Top 3 airlines flying from Chicago to Des Moines
Discover the top 3 airlines that operate flights from Chicago to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$189 | Average$359 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$433 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$209 | Average$419 | FlexibilityNo cancel fee | On-time63% |