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$44+ Cheap flights from South Carolina to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CHI
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from South Carolina to Chicago

Keep the following information in mind while searching for South Carolina to Chicago flight deals. Data was last updated April 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$149
(Cheapflightsfares)

One-way from

$47
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$366

Good round-trip deal

$187 or less

Good one-way deal

$134 or less
Provider with most accurate pricing for Myrtle Beach Intl-Chicago (CHI) flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Chicago (CHI) flights.
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From South Carolina to Chicago (CHI)
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One-way flight from South Carolina to Chicago (CHI)
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Highest demand for flights based on searches. 22% potential increase in price ($82 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from South Carolina to Chicago (CHI).
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Price to beat on a one-way flight from South Carolina to Chicago (CHI).
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Find flight deals from South Carolina to Chicago

Cheapest flights from South Carolina to Chicago
Explore the most affordable flight options available from South Carolina to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1611:36 amMYR - ORD
Nonstop2h 10mSpirit Airlines
Mon 5/192:19 pmORD - MYR
Nonstop1h 58mSpirit Airlines
Deal found 4/29$143
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/69:40 amCLT - ORD
1 stop5h 26mMultiple Airlines
Sun 6/86:05 pmORD - CLT
Nonstop2h 07mMultiple Airlines
Deal found 4/28$157
This Cheapflightsfares deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/299:02 pmCLT - ORD
1 stop12h 48mSpirit Airlines
Sat 5/317:47 amORD - CLT
1 stop7h 04mSpirit Airlines
Deal found 4/28$160
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/312:25 pmCLT - MDW
Nonstop1h 55mSouthwest
Sat 7/59:10 amMDW - CLT
Nonstop1h 50mSouthwest
Deal found 4/27$161
This Cheapflightsfares deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2610:03 pmCLT - ORD
Nonstop2h 25mFrontier
Sun 6/294:04 pmORD - CLT
Nonstop2h 07mFrontier
Deal found 4/28$166
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/111:15 amCLT - ORD
Nonstop2h 15mUnited Airlines
Wed 7/92:02 pmORD - CLT
Nonstop2h 10mUnited Airlines
Deal found 4/28$185
This Priceline deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/103:23 pmCAE - ORD
1 stop5h 40mSpirit Airlines
Sun 6/155:15 amORD - CAE
1 stop6h 08mSpirit Airlines
Deal found 4/29$189
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/97:44 amCLT - MDW
1 stop5h 40mFrontier
Mon 5/1212:15 pmMDW - CLT
1 stop6h 39mFrontier
Deal found 4/28$190
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/36:00 amCLT - MDW
1 stop3h 41mDelta
Sat 7/510:26 amMDW - CLT
1 stop6h 54mDelta
Deal found 4/27$197
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/97:06 pmSAV - ORD
1 stop5h 52mDelta
Fri 6/208:29 amORD - SAV
1 stop5h 01mDelta
Deal found 4/29$197
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/245:55 pmCAE - ORD
1 stop6h 22mDelta
Sun 5/255:30 amORD - CAE
1 stop6h 33mDelta
Deal found 4/28$199
This Booking.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/161:20 pmMYR - ORD
1 stop6h 49mMultiple Airlines
Mon 5/192:19 pmORD - MYR
Nonstop1h 58mMultiple Airlines
Deal found 4/28$204

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from South Carolina to Chicago that are best for you.

Fly from

South Carolina

Fly to

Chicago

Route

Depart

Return

Price

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 5/16

11:36 am-12:46 pm

Nonstop2h 10m

Chicago O'Hare Intl

Mon 5/19

2:19 pm-5:17 pm

Nonstop1h 58m

$143

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 6/6

9:40 am-2:06 pm

1 stop5h 26m

Chicago O'Hare Intl

Sun 6/8

6:05 pm-9:12 pm

Nonstop2h 07m

$157

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 5/29

9:02 pm-8:50 am

1 stop12h 48m

Chicago O'Hare Intl

Sat 5/31

7:47 am-3:51 pm

1 stop7h 04m

$160

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 7/3

12:25 pm-1:20 pm

Nonstop1h 55m

Chicago Midway

Sat 7/5

9:10 am-12:00 pm

Nonstop1h 50m

$161

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 6/26

10:03 pm-11:28 pm

Nonstop2h 25m

Chicago O'Hare Intl

Sun 6/29

4:04 pm-7:11 pm

Nonstop2h 07m

$166

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Tue 7/1

11:15 am-12:30 pm

Nonstop2h 15m

Chicago O'Hare Intl

Wed 7/9

2:02 pm-5:12 pm

Nonstop2h 10m

$185

ColumbiaChicago

CAE - ORD

CAEORD

Columbia Metropolitan

Tue 6/10

3:23 pm-8:03 pm

1 stop5h 40m

Chicago O'Hare Intl

Sun 6/15

5:15 am-12:23 pm

1 stop6h 08m

$189

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Fri 5/9

7:44 am-12:24 pm

1 stop5h 40m

Chicago Midway

Mon 5/12

12:15 pm-7:54 pm

1 stop6h 39m

$190

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Sat 5/24

6:22 pm-7:35 pm

Nonstop2h 13m

Chicago O'Hare Intl

Sun 6/1

7:00 am-10:05 am

Nonstop2h 05m

$194

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 7/3

6:00 am-8:41 am

1 stop3h 41m

Chicago Midway

Sat 7/5

10:26 am-6:20 pm

1 stop6h 54m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Chicago

What is the cheapest month to book a flight from South Carolina to Chicago?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $245). Flying from South Carolina to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to CHI?

Find hourly flight availability from South Carolina to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Chicago as you normally would.

Rainfall in Chicago by month

Plan your trip to Chicago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Chicago ranges from 1.7 - 4.9 inches per month. August is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Chicago when rainfall is around 1.7 in.

Temperature in Chicago by month

Plan your trip to Chicago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Chicago, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated April 30, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Southwest and Delta from South Carolina to Chicago by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,961 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,295 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,936 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Avelo Airlines
7.5
Good
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,696 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Crew

8.5

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Chicago one-way?

    $47 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on United Airlines and Southwest, with prices starting from $79 and $81, respectively.

  • What are the most popular routes from South Carolina to Chicago?

    While some choose either Charleston - Chicago O'Hare Intl or Savannah/Hilton Head - Chicago O'Hare Intl, Charlotte Douglas - Chicago O'Hare Intl is the most popular route from South Carolina to Chicago.

  • What are the most reliable airlines from South Carolina to Chicago?

    Consider ANA (90%), Air Canada (88%) or Air New Zealand (88%) when booking your flight. These represent the most reliable airlines when flying from South Carolina to Chicago.

  • What are the cheapest flights from South Carolina to Chicago?

    The cheapest flight price from South Carolina to Chicago is $139. On average you can expect to pay $887. The most popular route, (Charlotte Douglas - Chicago O'Hare Intl), can usually be booked for $122.

  • Can I find deals for flights from South Carolina to Chicago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Chicago.

  • Can I find deals for business class flights from South Carolina to Chicago?

    Yes. Cheapflights offers flight deals from South Carolina to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Chicago?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $245). Flying from South Carolina to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Merrillville
Hammond
Benton Harbor
Porter
Lansing
Valparaiso
Chesterton

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Alternative routes for South Carolina to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Chicago

Discover the top 5 airlines that operate flights from South Carolina to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$59Average$150FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$167Average$351FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$173Average$381FlexibilityNo cancel feeOn-time69%
DeltaCheapest$176Average$374FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$266Average$405FlexibilityNo cancel feeOn-time63%

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