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$43+ Cheap flights from South Carolina to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CHI
dic. 4 — dic. 111
jue. 12/4
jue. 12/11
1 adult, Economy
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Find flight deals from South Carolina to Chicago

Cheapest flights from South Carolina to Chicago
Explore the most affordable flight options available from South Carolina to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 4, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/206:00 amCLT - ORD
1 stop9h 31mMultiple Airlines
lun. 12/158:50 amORD - CLT
Nonstop2h 07mMultiple Airlines
Deal found 11/2$93
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/244:17 pmCLT - ORD
Nonstop2h 22mFrontier
vie. 11/2812:29 pmORD - CLT
Nonstop2h 03mFrontier
Deal found 11/3$94
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/185:45 amCLT - ORD
1 stop6h 35mMultiple Airlines
dom. 12/148:55 amORD - CLT
Nonstop2h 07mMultiple Airlines
Deal found 11/2$96
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/224:17 pmCLT - ORD
Nonstop2h 22mFrontier
dom. 11/2312:29 pmORD - CLT
Nonstop2h 03mFrontier
Deal found 11/4$97
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/812:52 pmCLT - ORD
Nonstop2h 13mFrontier
vie. 12/1212:15 pmORD - CLT
1 stop6h 45mFrontier
Deal found 11/4$98
This Booking.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/244:17 pmCLT - ORD
Nonstop2h 22mFrontier
mié. 11/266:30 amORD - CLT
1 stop13h 57mFrontier
Deal found 11/4$99
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/174:27 pmCLT - ORD
1 stop9h 32mFrontier
vie. 12/128:50 amORD - CLT
Nonstop2h 07mFrontier
Deal found 11/2$101
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/1610:51 pmCLT - ORD
1 stop9h 35mFrontier
lun. 12/158:50 amORD - CLT
Nonstop2h 07mFrontier
Deal found 11/2$102
This Priceline deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/119:17 amCLT - ORD
Nonstop2h 13mFrontier
dom. 12/148:55 amORD - CLT
Nonstop2h 07mFrontier
Deal found 11/3$103
This Priceline deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1212:52 pmCLT - ORD
Nonstop2h 13mFrontier
dom. 12/148:55 amORD - CLT
Nonstop2h 07mFrontier
Deal found 11/1$105
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/153:51 pmCLT - ORD
Nonstop2h 22mFrontier
jue. 11/203:37 pmORD - CLT
1 stop14h 41mFrontier
Deal found 11/3$106
This Priceline deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/43:42 pmCLT - MDW
1 stop7h 11mFrontier
dom. 12/78:05 amMDW - CLT
1 stop8h 42mFrontier
Deal found 11/4$124

Cheap flight deals from South Carolina to Chicago

Keep the following information in mind while searching for South Carolina to Chicago flight deals. Data was last updated noviembre 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$91
(Frontier)

One-way from

$43
(Booking.com)

Popular in

December

Cheapest in

August

Average price

$397

Good round-trip deal

$294 or less

Good one-way deal

$184 or less
Provider with most accurate pricing for Myrtle Beach Intl-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Chicago (CHI) flights.
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From South Carolina to Chicago (CHI)
Search Deals
One-way flight from South Carolina to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($78 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from South Carolina to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from South Carolina to Chicago (CHI).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 4, 2025.
Use the filters below to find and compare flights from South Carolina to Chicago that are best for you.

Fly from

South Carolina

Fly to

Chicago

Route

Depart

Return

Price

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

jue. 11/20

10:47 am-4:30 pm

1 stop6h 43m

Chicago Midway

vie. 11/21

8:41 pm-7:54 am

1 stop10h 13m

$127

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

mié. 12/24

6:20 pm-7:25 pm

Nonstop2h 05m

Chicago Midway

mié. 12/31

6:00 pm-8:50 pm

Nonstop1h 50m

$139

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

vie. 11/21

3:24 pm-7:31 pm

1 stop5h 07m

Chicago Midway

sáb. 11/22

12:25 pm-7:35 pm

1 stop6h 10m

$144

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

lun. 11/24

7:45 pm-8:45 pm

Nonstop2h 00m

Chicago Midway

jue. 11/27

5:35 am-12:05 pm

1 stop5h 30m

$149

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

jue. 12/4

5:28 pm-6:54 pm

Nonstop2h 26m

Chicago O'Hare Intl

sáb. 12/6

7:15 am-10:32 am

Nonstop2h 17m

$151

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

vie. 11/21

3:24 pm-7:31 pm

1 stop5h 07m

Chicago Midway

dom. 11/23

12:25 pm-11:01 am

1 stop21h 36m

$152

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

jue. 1/8

5:50 pm-6:55 pm

Nonstop2h 05m

Chicago Midway

mar. 1/13

1:30 pm-4:20 pm

Nonstop1h 50m

$158

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

lun. 12/8

6:10 am-7:15 am

Nonstop2h 05m

Chicago Midway

vie. 12/12

8:20 pm-11:10 pm

Nonstop1h 50m

$163

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

jue. 12/11

6:10 am-7:15 am

Nonstop2h 05m

Chicago Midway

dom. 12/14

9:30 am-12:25 pm

Nonstop1h 55m

$163

SavannahChicago

SAV - ORD

SAVORD

Savannah/Hilton Head

lun. 12/8

7:30 am-11:08 am

1 stop28h 38m

Chicago O'Hare Intl

jue. 12/11

6:15 am-11:18 pm

1 stop16h 03m

$166

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Chicago

What is the cheapest month to book a flight from South Carolina to Chicago?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $98). Flying from South Carolina to Chicago in February is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to CHI?

Find hourly flight availability from South Carolina to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 4, 2025.

When flying from South Carolina to Chicago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 16% versus a flight in the afternoon.

What is the cheapest day to fly from South Carolina to Chicago?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Chicago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Chicago flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from South Carolina to Chicago

Explore weekly flight availability from South Carolina to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated noviembre 4, 2025.

The most flights from USSC to CHI are scheduled on a Monday (22 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (12 on average).

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Chicago?

    Frontier, Southwest, and United Airlines can get you from South Carolina to Chicago in just under 2h 05m. Your travel time can differ by up to 6h 06m. Airlines will cover a distance of 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Chicago one-way?

    $61 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Southwest and United Airlines, with prices starting from $70 and $70, respectively.

  • What are the most popular routes from South Carolina to Chicago?

    While some choose either Charleston - Chicago O'Hare Intl or Charlotte Douglas - Chicago Midway, Charlotte Douglas - Chicago O'Hare Intl is the most popular route from South Carolina to Chicago.

  • What are the most reliable airlines from South Carolina to Chicago?

    Consider Qatar Airways (94%), ANA (89%) or Air Canada (85%) when booking your flight. These represent the most reliable airlines when flying from South Carolina to Chicago.

  • What are the cheapest flights from South Carolina to Chicago?

    The cheapest flight price from South Carolina to Chicago is $136. On average you can expect to pay $1,772. The most popular route, (Charlotte Douglas - Chicago O'Hare Intl), can usually be booked for $103.

  • Can I find deals for flights from South Carolina to Chicago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Chicago.

  • Can I find deals for business class flights from South Carolina to Chicago?

    Yes. Cheapflights offers flight deals from South Carolina to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Chicago?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $98). Flying from South Carolina to Chicago in February is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
Lansing
Hammond
Porter
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Alternative routes for South Carolina to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Chicago

Discover the top 5 airlines that operate flights from South Carolina to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$93Average$195FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$135Average$342FlexibilityNo cancel feeOn-time71%
DeltaCheapest$180Average$381FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$190Average$375FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$193Average$381FlexibilityNo cancel feeOn-time69%

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