HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Chicago

$64+ Cheap flights from South Carolina to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CHI
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Chicago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Chicago

Keep the following information in mind while searching for South Carolina to Chicago flight deals. Data was last updated September 11, 2025.

Round-trip from

$122
(Kiwi.com)

One-way from

$64
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$224

Good round-trip deal

$261 or less

Good one-way deal

$119 or less
From South Carolina to Chicago (CHI)
Search Deals
One-way flight from South Carolina to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals
Price to beat on a round-trip flight from South Carolina to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from South Carolina to Chicago (CHI).
Search Deals

Find flight deals from South Carolina to Chicago

Cheapest flights from South Carolina to Chicago
Explore the most affordable flight options available from South Carolina to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/211:50 amCLT - ORD
Nonstop2h 22mMultiple Airlines
Wed 10/86:40 amORD - CLT
1 stop15h 49mMultiple Airlines
Deal found 9/9$123
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2512:00 pmCLT - ORD
1 stop6h 05mMultiple Airlines
Mon 10/275:50 amORD - CLT
Nonstop2h 10mMultiple Airlines
Deal found 9/10$124
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/21:11 pmCLT - ORD
1 stop11h 47mFrontier
Thu 10/96:00 amORD - CLT
Nonstop2h 08mFrontier
Deal found 9/9$125
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:45 amCLT - ORD
2 stops17h 13mMultiple Airlines
Fri 10/105:50 amORD - CLT
Nonstop2h 10mMultiple Airlines
Deal found 9/9$128
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1210:03 amCLT - ORD
Nonstop2h 15mFrontier
Thu 10/166:00 amORD - CLT
Nonstop2h 08mFrontier
Deal found 9/9$129
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/211:50 amCLT - ORD
Nonstop2h 22mMultiple Airlines
Fri 10/1010:27 amORD - CLT
1 stop6h 35mMultiple Airlines
Deal found 9/9$131
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/93:09 pmCLT - ORD
1 stop9h 36mMultiple Airlines
Thu 10/166:00 amORD - CLT
Nonstop2h 08mMultiple Airlines
Deal found 9/9$132
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:10 amCLT - MDW
Nonstop2h 05mSouthwest
Sun 11/168:20 pmMDW - CLT
Nonstop1h 50mSouthwest
Deal found 9/11$133
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:10 pmCLT - ORD
Nonstop2h 25mUnited Airlines
Sun 10/51:55 pmORD - CLT
Nonstop2h 10mUnited Airlines
Deal found 9/10$133
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/142:40 pmCLT - ORD
1 stop7h 53mSpirit Airlines
Sat 10/1811:12 amORD - CLT
1 stop9h 27mSpirit Airlines
Deal found 9/10$134
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1210:03 amCLT - ORD
Nonstop2h 15mFrontier
Sun 10/196:00 amORD - CLT
Nonstop2h 08mFrontier
Deal found 9/9$136
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/254:00 pmCLT - ORD
1 stop16h 14mFrontier
Mon 10/275:50 amORD - CLT
Nonstop2h 10mFrontier
Deal found 9/10$137

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from South Carolina to Chicago that are best for you.

Fly from

South Carolina

Fly to

Chicago

Route

Depart

Return

Price

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Wed 11/12

6:10 am-7:15 am

Nonstop2h 05m

Chicago Midway

Sun 11/16

8:20 pm-11:10 pm

Nonstop1h 50m

$133

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 10/1

10:25 am-11:36 am

Nonstop2h 11m

Chicago O'Hare Intl

Fri 10/3

6:20 pm-9:41 pm

Nonstop2h 21m

$133

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Mon 10/6

6:30 am-7:50 am

Nonstop2h 20m

Chicago O'Hare Intl

Wed 10/8

7:15 am-10:31 am

Nonstop2h 16m

$133

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 10/23

6:30 am-7:50 am

Nonstop2h 20m

Chicago O'Hare Intl

Sat 10/25

1:55 pm-5:05 pm

Nonstop2h 10m

$133

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 10/10

10:25 am-11:36 am

Nonstop2h 11m

Chicago O'Hare Intl

Tue 10/14

1:55 pm-5:05 pm

Nonstop2h 10m

$133

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Tue 12/30

6:20 am-7:41 am

Nonstop2h 21m

Chicago O'Hare Intl

Thu 1/1

6:25 pm-9:40 pm

Nonstop2h 15m

$133

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Sat 10/4

6:30 am-7:50 am

Nonstop2h 20m

Chicago O'Hare Intl

Sun 10/5

7:15 am-10:31 am

Nonstop2h 16m

$133

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 10/1

10:34 am-2:34 pm

1 stop5h 00m

Chicago O'Hare Intl

Wed 10/15

7:15 am-10:31 am

Nonstop2h 16m

$143

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 10/8

7:46 pm-11:15 pm

1 stop4h 29m

Chicago O'Hare Intl

Wed 10/15

1:55 pm-5:05 pm

Nonstop2h 10m

$143

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Wed 10/1

6:30 am-7:25 am

Nonstop1h 55m

Chicago Midway

Wed 10/15

10:35 am-1:25 pm

Nonstop1h 50m

$160

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from South Carolina to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Chicago

What is the cheapest month to book a flight from South Carolina to Chicago?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $245). Flying from South Carolina to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to CHI?

Find hourly flight availability from South Carolina to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Chicago as you normally would.

Weekly flight availability from South Carolina to Chicago

Explore weekly flight availability from South Carolina to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 11, 2025.

The most flights from USSC to CHI are scheduled on a Wednesday (20 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (14 on average).

How much does it cost to fly round-trip from South Carolina to Chicago?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Chicago?

    Southwest, United Airlines, and Spirit Airlines can get you from South Carolina to Chicago in just under 2h 05m. Your travel time can differ by up to 4h 38m. Airlines will cover a distance of 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Chicago one-way?

    $67 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Southwest and American Airlines, with prices starting from $67 and $77, respectively.

  • What are the most popular routes from South Carolina to Chicago?

    While some choose either Charleston - Chicago O'Hare Intl or Charlotte Douglas - Chicago Midway, Charlotte Douglas - Chicago O'Hare Intl is the most popular route from South Carolina to Chicago.

  • What are the most reliable airlines from South Carolina to Chicago?

    Consider ANA (87%), Air Canada (77%) or Air New Zealand (77%) when booking your flight. These represent the most reliable airlines when flying from South Carolina to Chicago.

  • What are the cheapest flights from South Carolina to Chicago?

    The cheapest flight price from South Carolina to Chicago is $104. On average you can expect to pay $1,879. The most popular route, (Charlotte Douglas - Chicago O'Hare Intl), can usually be booked for $114.

  • Can I find deals for flights from South Carolina to Chicago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Chicago.

  • Can I find deals for business class flights from South Carolina to Chicago?

    Yes. Cheapflights offers flight deals from South Carolina to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Chicago?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $245). Flying from South Carolina to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
Lansing
Hammond
Benton Harbor
Porter
Chesterton

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to O'Hare Intl flights
John F Kennedy Intl to O'Hare Intl flights
LaGuardia to O'Hare Intl flights
Newark to O'Hare Intl flights
Los Angeles to O'Hare Intl flights
Reagan-National to O'Hare Intl flights
Boston to O'Hare Intl flights
Dulles Intl to O'Hare Intl flights
San Francisco to O'Hare Intl flights
Baltimore to O'Hare Intl flights
Atlanta to O'Hare Intl flights
Dallas/Fort Worth to Midway flights
John F Kennedy Intl to Midway flights
Seattle to O'Hare Intl flights
Ontario to O'Hare Intl flights
Denver to O'Hare Intl flights
Philadelphia to O'Hare Intl flights
Baltimore to Midway flights
Santa Ana to O'Hare Intl flights
Atlanta to Midway flights
LaGuardia to Midway flights
Los Angeles to Midway flights
Dulles Intl to Midway flights
Sky Harbor Intl to O'Hare Intl flights
Hobby to Midway flights
Hobby to O'Hare Intl flights
San Francisco to Midway flights
Burbank to O'Hare Intl flights
Newark to Midway flights
Austin to O'Hare Intl flights
George Bush Intcntl to O'Hare Intl flights
Minneapolis to O'Hare Intl flights
Charlotte to O'Hare Intl flights
San Jose to O'Hare Intl flights
Portland to O'Hare Intl flights
Philadelphia to Midway flights
Minneapolis to Midway flights
Orlando to O'Hare Intl flights
San Diego to O'Hare Intl flights
Raleigh to O'Hare Intl flights
Fort Lauderdale to O'Hare Intl flights
Boston to Midway flights
Denver to Midway flights
Reagan-National to Midway flights
Tampa to O'Hare Intl flights
Seattle to Midway flights
Love Field to O'Hare Intl flights
Miami to O'Hare Intl flights
Cleveland to O'Hare Intl flights
Oakland to O'Hare Intl flights

Top 5 airlines flying from South Carolina to Chicago

Discover the top 5 airlines that operate flights from South Carolina to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$46Average$173FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$135Average$339FlexibilityNo cancel feeOn-time71%
DeltaCheapest$180Average$369FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$190Average$393FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$193Average$388FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.