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$45+ Cheap flights from South Carolina to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CHI
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from South Carolina to Chicago

Cheapest flights from South Carolina to Chicago
Explore the most affordable flight options available from South Carolina to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This Super.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:39 pmCLT - ORD
1 stop6h 27mFrontier
Thu 1/15:25 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/22$118
This Frontier deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:39 pmCLT - ORD
1 stop6h 27mFrontier
Fri 1/25:45 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/22$121
This Frontier deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:52 amCLT - ORD
Nonstop2h 13mFrontier
Sun 1/45:05 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/21$135
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:09 pmCLT - ORD
Nonstop2h 31mUnited Airlines
Thu 1/12:26 pmORD - CLT
Nonstop2h 12mUnited Airlines
Deal found 12/22$139
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:14 pmCLT - ORD
1 stop27h 52mMultiple Airlines
Thu 1/15:25 amORD - CLT
Nonstop2h 07mMultiple Airlines
Deal found 12/22$160
This Super.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:52 amCLT - ORD
Nonstop2h 13mFrontier
Thu 1/15:25 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/22$162
This Frontier deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:52 amCLT - ORD
Nonstop2h 13mFrontier
Fri 1/25:45 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/22$165
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:39 pmCLT - ORD
1 stop6h 27mFrontier
Wed 1/75:29 pmORD - CLT
1 stop13h 23mFrontier
Deal found 12/22$169
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:39 pmCLT - ORD
1 stop6h 27mFrontier
Sun 1/45:05 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/22$174
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:36 pmGSP - ORD
Nonstop2h 19mUnited Airlines
Wed 1/71:55 pmORD - GSP
Nonstop1h 57mUnited Airlines
Deal found 12/21$222
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:34 amGSP - ORD
Nonstop2h 21mUnited Airlines
Mon 1/57:50 amORD - GSP
Nonstop2h 06mUnited Airlines
Deal found 12/22$247
This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:40 amGSP - ORD
1 stop5h 40mUnited Airlines
Tue 1/271:00 pmORD - GSP
1 stop5h 29mUnited Airlines
Deal found 12/22$249

Find flight deals from South Carolina to Chicago

Keep the following information in mind while searching for South Carolina to Chicago flight deals. Data was last updated December 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$72
(Kiwi.com)

One-way from

$45
(Priceline)

Popular in

December

Cheapest in

August

Average price

$459

Good round-trip deal

$279 or less

Good one-way deal

$182 or less
Provider with most accurate pricing for Myrtle Beach Intl-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Chicago (CHI) flights.
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From South Carolina to Chicago (CHI)
Search Deals
One-way flight from South Carolina to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($75 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from South Carolina to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from South Carolina to Chicago (CHI).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from South Carolina to Chicago that are best for you.

Fly from

South Carolina

Fly to

Chicago

Route

Depart

Return

Price

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 1/21

6:10 am-7:43 am

Nonstop2h 33m

Chicago O'Hare Intl

Wed 1/28

7:17 am-10:33 am

Nonstop2h 16m

$139

ColumbiaChicago

CAE - ORD

CAEORD

Columbia Metropolitan

Thu 2/5

3:08 pm-10:36 pm

1 stop8h 28m

Chicago O'Hare Intl

Sun 2/8

5:15 am-2:18 pm

1 stop8h 03m

$152

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 2/4

5:35 pm-6:55 pm

Nonstop2h 20m

Chicago O'Hare Intl

Fri 2/6

7:17 am-10:33 am

Nonstop2h 16m

$158

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Sat 1/31

10:44 am-12:12 pm

Nonstop2h 28m

Chicago O'Hare Intl

Sun 2/1

2:18 pm-5:24 pm

Nonstop2h 06m

$158

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Sat 1/31

7:00 am-6:16 pm

1 stop12h 16m

Chicago O'Hare Intl

Sun 2/1

4:38 pm-11:59 pm

1 stop6h 21m

$165

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Sat 1/10

6:00 am-10:36 pm

2 stops17h 36m

Chicago O'Hare Intl

Tue 1/13

6:05 am-4:43 pm

1 stop9h 38m

$173

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Wed 1/21

7:59 am-11:59 am

1 stop5h 00m

Chicago Midway

Wed 1/21

6:14 pm-11:54 pm

1 stop4h 40m

$177

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Fri 2/20

8:25 pm-9:30 pm

Nonstop2h 05m

Chicago Midway

Sun 2/22

7:35 pm-10:30 pm

Nonstop1h 55m

$177

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 12/31

4:05 pm-8:36 pm

1 stop5h 31m

Chicago O'Hare Intl

Thu 1/1

7:00 am-12:25 pm

1 stop4h 25m

$177

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 2/27

5:55 am-11:22 am

1 stop6h 27m

Chicago O'Hare Intl

Sun 3/1

5:58 pm-8:12 pm

1 stop25h 14m

$180

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Chicago

What is the cheapest month to book a flight from South Carolina to Chicago?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $96). Flying from South Carolina to Chicago in February is currently the most expensive (average of $205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to CHI?

Find hourly flight availability from South Carolina to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

When flying from South Carolina to Chicago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 19% versus a flight at noon.

What is the cheapest day to fly from South Carolina to Chicago?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Chicago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Chicago flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from South Carolina to Chicago

Explore weekly flight availability from South Carolina to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 23, 2025.

The most flights from USSC to CHI are scheduled on a Tuesday (20 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (5 on average).

How much does it cost to fly round-trip from South Carolina to Chicago?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Chicago?

    United Airlines, Spirit Airlines, and Delta can get you from South Carolina to Chicago in just under 2h 33m. Your travel time can differ by up to 9h 43m. Airlines will cover a distance of 599 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Chicago one-way?

    $107 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Volaris and Spirit Airlines, with prices starting from $108 and $113, respectively.

  • What are the most popular routes from South Carolina to Chicago?

    While some choose either Charlotte Douglas - Chicago Midway or Charleston - Chicago O'Hare Intl, Charlotte Douglas - Chicago O'Hare Intl is the most popular route from South Carolina to Chicago.

  • What are the most reliable airlines from South Carolina to Chicago?

    Consider ANA (84%), Qatar Airways (78%) or Envoy Air (76%) when booking your flight. These represent the most reliable airlines when flying from South Carolina to Chicago.

  • What are the cheapest flights from South Carolina to Chicago?

    The cheapest flight price from South Carolina to Chicago is $132. On average you can expect to pay $898. The most popular route, (Charlotte Douglas - Chicago O'Hare Intl), can usually be booked for $86.

  • Can I find deals for flights from South Carolina to Chicago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Chicago.

  • Can I find deals for business class flights from South Carolina to Chicago?

    Yes. Cheapflights offers flight deals from South Carolina to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Chicago?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $96). Flying from South Carolina to Chicago in February is currently the most expensive (average of $205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lansing
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Hammond
Porter
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Alternative routes for South Carolina to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Chicago

Discover the top 5 airlines that operate flights from South Carolina to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$93Average$196FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$135Average$336FlexibilityNo cancel feeOn-time71%
DeltaCheapest$180Average$385FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$190Average$376FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$193Average$377FlexibilityNo cancel feeOn-time69%

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