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$47+ Cheap flights from South Carolina to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CHI
ago. 5 — ago. 121
mar. 8/5
mar. 8/12
1 adult, Economy
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Cheap flight deals from South Carolina to Chicago

Keep the following information in mind while searching for South Carolina to Chicago flight deals. Data was last updated julio 31, 2025.

Round-trip from

$94
(Mytrip)

One-way from

$47
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$286

Good round-trip deal

$191 or less

Good one-way deal

$150 or less
From South Carolina to Chicago (CHI)
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One-way flight from South Carolina to Chicago (CHI)
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Highest demand for flights based on searches. 18% potential increase in price ($69 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from South Carolina to Chicago (CHI).
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Price to beat on a one-way flight from South Carolina to Chicago (CHI).
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Find flight deals from South Carolina to Chicago

Cheapest flights from South Carolina to Chicago
Explore the most affordable flight options available from South Carolina to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 31, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/212:18 pmMYR - ORD
Nonstop2h 25mSpirit Airlines
dom. 8/2410:12 amORD - MYR
Nonstop2h 01mSpirit Airlines
Deal found 7/29$89
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/305:20 pmCLT - MDW
Nonstop2h 00mSouthwest
dom. 8/314:45 pmMDW - CLT
Nonstop1h 55mSouthwest
Deal found 7/30$141
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/35:50 pmCLT - ORD
Nonstop2h 15mAmerican Airlines
dom. 9/75:00 amORD - CLT
Nonstop2h 05mAmerican Airlines
Deal found 7/30$141
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/56:40 amCLT - ORD
Nonstop2h 20mUnited Airlines
dom. 9/77:10 amORD - CLT
Nonstop2h 14mUnited Airlines
Deal found 7/30$143
This Frontier deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/18:44 pmCLT - ORD
Nonstop2h 30mFrontier
jue. 9/47:40 amORD - CLT
Nonstop2h 20mFrontier
Deal found 7/31$144
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/73:25 pmCLT - ORD
Nonstop2h 22mMultiple Airlines
dom. 11/99:18 amORD - CLT
1 stop8h 29mMultiple Airlines
Deal found 7/31$145
This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/154:48 pmCLT - ORD
1 stop8h 11mSpirit Airlines
lun. 8/188:12 pmORD - CLT
1 stop12h 04mSpirit Airlines
Deal found 7/29$160
This Booking.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/144:20 pmCAE - ORD
1 stop7h 02mSpirit Airlines
dom. 8/176:56 amORD - CAE
1 stop7h 22mSpirit Airlines
Deal found 7/30$174
This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/295:32 pmCLT - MDW
1 stop7h 52mFrontier
dom. 8/313:36 pmMDW - CLT
1 stop5h 17mFrontier
Deal found 7/29$176
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/136:16 pmCHS - ORD
Nonstop2h 33mAmerican Airlines
sáb. 9/208:07 amORD - CHS
Nonstop2h 23mAmerican Airlines
Deal found 7/30$180
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/196:35 amCHS - MDW
Nonstop2h 05mSouthwest
mié. 8/276:05 pmMDW - CHS
Nonstop2h 10mSouthwest
Deal found 7/29$181
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/155:50 pmCHS - ORD
1 stop6h 40mUnited Airlines
mié. 10/227:10 amORD - CHS
Nonstop2h 25mUnited Airlines
Deal found 7/31$187

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from South Carolina to Chicago that are best for you.

Fly from

South Carolina

Fly to

Chicago

Route

Depart

Return

Price

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

jue. 8/21

2:18 pm-3:43 pm

Nonstop2h 25m

Chicago O'Hare Intl

dom. 8/24

10:12 am-1:13 pm

Nonstop2h 01m

$89

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

sáb. 8/30

5:20 pm-6:20 pm

Nonstop2h 00m

Chicago Midway

dom. 8/31

4:45 pm-7:40 pm

Nonstop1h 55m

$141

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

mié. 9/3

5:50 pm-7:05 pm

Nonstop2h 15m

Chicago O'Hare Intl

dom. 9/7

5:00 am-8:05 am

Nonstop2h 05m

$141

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

vie. 9/5

6:40 am-8:00 am

Nonstop2h 20m

Chicago O'Hare Intl

dom. 9/7

7:10 am-10:24 am

Nonstop2h 14m

$143

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

lun. 9/1

8:44 pm-10:14 pm

Nonstop2h 30m

Chicago O'Hare Intl

jue. 9/4

7:40 am-11:00 am

Nonstop2h 20m

$144

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

mié. 8/20

4:48 pm-11:59 pm

1 stop8h 11m

Chicago O'Hare Intl

vie. 8/22

1:47 pm-5:03 pm

Nonstop2h 16m

$146

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

vie. 8/15

4:48 pm-11:59 pm

1 stop8h 11m

Chicago O'Hare Intl

lun. 8/18

8:12 pm-9:16 am

1 stop12h 04m

$160

ColumbiaChicago

CAE - ORD

CAEORD

Columbia Metropolitan

jue. 8/14

4:20 pm-10:22 pm

1 stop7h 02m

Chicago O'Hare Intl

dom. 8/17

6:56 am-3:18 pm

1 stop7h 22m

$174

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

vie. 8/29

5:32 pm-12:24 am

1 stop7h 52m

Chicago Midway

dom. 8/31

3:36 pm-9:53 pm

1 stop5h 17m

$176

CharlestonChicago

CHS - ORD

CHSORD

Charleston

sáb. 9/13

6:16 pm-7:49 pm

Nonstop2h 33m

Chicago O'Hare Intl

sáb. 9/20

8:07 am-11:30 am

Nonstop2h 23m

$180

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Chicago

What is the cheapest month to book a flight from South Carolina to Chicago?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $245). Flying from South Carolina to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to CHI?

Find hourly flight availability from South Carolina to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Chicago as you normally would.

Weekly flight availability from South Carolina to Chicago

Explore weekly flight availability from South Carolina to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated julio 31, 2025.

The most flights from USSC to CHI are scheduled on a Thursday (22 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (9 on average).

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated julio 31, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from South Carolina to Chicago. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,900 reviews
Southwest
8.0
Very good
4,246 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
JetBlue
7.3
Good
2,914 reviews
Southwest
8.0
Very good
4,246 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Chicago one-way?

    $47 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Southwest and United Airlines, with prices starting from $72 and $72, respectively.

  • What are the most popular routes from South Carolina to Chicago?

    While some choose either Charleston - Chicago O'Hare Intl or Greenville - Chicago O'Hare Intl, Charlotte Douglas - Chicago O'Hare Intl is the most popular route from South Carolina to Chicago.

  • What are the most reliable airlines from South Carolina to Chicago?

    Consider ANA (91%), Alaska Airlines (87%) or Qatar Airways (84%) when booking your flight. These represent the most reliable airlines when flying from South Carolina to Chicago.

  • What are the cheapest flights from South Carolina to Chicago?

    The cheapest flight price from South Carolina to Chicago is $90. On average you can expect to pay $1,997. The most popular route, (Charlotte Douglas - Chicago O'Hare Intl), can usually be booked for $128.

  • Can I find deals for flights from South Carolina to Chicago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Chicago.

  • Can I find deals for business class flights from South Carolina to Chicago?

    Yes. Cheapflights offers flight deals from South Carolina to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Chicago?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $245). Flying from South Carolina to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
Lansing
Hammond
Benton Harbor
Porter
Valparaiso
Chesterton

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Alternative routes for South Carolina to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Chicago

Discover the top 5 airlines that operate flights from South Carolina to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$46Average$153FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$135Average$345FlexibilityNo cancel feeOn-time71%
DeltaCheapest$176Average$328FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$193Average$384FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$224Average$397FlexibilityNo cancel feeOn-time63%

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