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$78+ Cheap flights from Chicago (CHI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — CHS
Jun 4 — Jun 111
Thu 6/4
Thu 6/11
1 adult, Economy
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Cheap flight deals from Chicago to South Carolina

Cheapest flights from Chicago to South Carolina
Explore the most affordable flight options available from Chicago to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.

This Expedia deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:05 pm
ORD
-
CLT
1 stop22h 55m
Frontier
Wed 5/275:50 pm
CLT
-
ORD
1 stop19h 47m
Frontier
Deal found 4/30$160
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:05 am
ORD
-
CLT
1 stop8h 06m
Multiple Airlines
Sat 6/65:50 pm
CLT
-
ORD
1 stop19h 34m
Multiple Airlines
Deal found 5/1$166
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:05 am
ORD
-
CLT
1 stop10h 57m
Multiple Airlines
Mon 6/19:07 pm
CLT
-
ORD
1 stop16h 17m
Multiple Airlines
Deal found 4/30$167
This Trip.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/204:05 pm
ORD
-
CLT
1 stop22h 55m
Frontier
Tue 5/265:50 pm
CLT
-
ORD
1 stop19h 47m
Frontier
Deal found 5/2$174
This Expedia deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:05 pm
ORD
-
CLT
1 stop22h 55m
Frontier
Sat 5/301:00 pm
CLT
-
ORD
1 stop11h 13m
Frontier
Deal found 4/30$180
This Expedia deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:11 pm
ORD
-
CLT
1 stop18h 01m
Frontier
Mon 5/255:58 pm
CLT
-
ORD
1 stop30h 03m
Frontier
Deal found 4/30$185
This Super.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:30 am
ORD
-
CLT
1 stop7h 56m
Frontier
Sun 5/171:46 pm
CLT
-
ORD
1 stop24h 08m
Frontier
Deal found 4/30$186
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:05 am
ORD
-
CLT
1 stop8h 06m
Multiple Airlines
Tue 6/96:10 am
CLT
-
ORD
1 stop6h 33m
Multiple Airlines
Deal found 4/30$187
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:05 am
ORD
-
CLT
1 stop8h 06m
Multiple Airlines
Sat 5/301:00 pm
CLT
-
ORD
1 stop6h 44m
Multiple Airlines
Deal found 4/30$188
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:30 am
ORD
-
CLT
1 stop9h 18m
Multiple Airlines
Tue 5/193:16 pm
CLT
-
ORD
1 stop8h 59m
Multiple Airlines
Deal found 4/30$189
This Expedia deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/169:48 pm
ORD
-
CLT
1 stop22h 37m
Frontier
Wed 6/246:33 pm
CLT
-
ORD
1 stop18h 51m
Frontier
Deal found 5/1$190
This CheapOair deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:11 pm
ORD
-
CLT
1 stop17h 54m
Frontier
Sat 6/65:50 pm
CLT
-
ORD
1 stop19h 34m
Frontier
Deal found 5/1$191

Find flight deals from Chicago to South Carolina

Keep the following information in mind while searching for Chicago to South Carolina flight deals. Data was last updated May 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$160
(Expedia)

One-way from

$78
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$346

Good round-trip deal

$325 or less

Good one-way deal

$172 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
Search Deals
From Chicago (CHI) to South Carolina
Search Deals
One-way flight from Chicago (CHI) to South Carolina
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals
Price to beat on a round-trip flight from Chicago (CHI) to South Carolina.
Search Deals
Price to beat on a one-way flight from Chicago (CHI) to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Chicago to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 6/13

5:50 pm-8:45 pm

Nonstop1h 55m

Charlotte Douglas

Wed 6/17

8:20 am-9:15 am

Nonstop1h 55m

$259

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 10/3

9:30 pm-12:50 am

Nonstop2h 20m

Charlotte Douglas

Tue 10/6

7:50 pm-11:15 pm

1 stop4h 25m

$269

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 8/1

6:15 pm-9:29 pm

Nonstop2h 14m

Charlotte Douglas

Sat 8/8

6:00 am-11:53 am

1 stop6h 53m

$269

ChicagoCharleston

ORD - CHS

ORDCHS

Chicago O'Hare Intl

Mon 5/25

7:07 am-12:10 pm

1 stop4h 03m

Charleston

Tue 6/2

1:17 pm-4:56 pm

1 stop4h 39m

$271

ChicagoCharleston

ORD - CHS

ORDCHS

Chicago O'Hare Intl

Sat 5/30

1:55 pm-7:10 pm

1 stop4h 15m

Charleston

Tue 6/2

6:40 am-12:50 pm

1 stop7h 10m

$271

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

Sat 5/30

10:42 am-2:16 pm

Nonstop2h 34m

Savannah/Hilton Head

Mon 6/1

6:10 pm-7:53 pm

Nonstop2h 43m

$271

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 5/30

7:00 am-11:55 am

1 stop3h 55m

Greenville

Tue 6/2

3:00 pm-6:41 pm

1 stop4h 41m

$275

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 8/29

5:55 pm-11:38 pm

1 stop4h 43m

Greenville

Sat 9/5

7:15 am-10:24 am

1 stop4h 09m

$275

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Tue 6/23

6:22 pm-11:59 pm

1 stop4h 37m

Myrtle Beach Intl

Fri 7/3

11:00 am-6:00 pm

1 stop8h 00m

$276

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 10/31

8:55 am-2:10 pm

1 stop4h 15m

Greenville

Tue 11/3

1:10 pm-2:12 pm

Nonstop2h 02m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Chicago to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to South Carolina

How far ahead should I book a flight from Chicago to South Carolina?

The price you pay for your flight from Chicago to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 42 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Chicago to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $50). Flying from Chicago to South Carolina in October is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to SC?

Find hourly flight availability from Chicago to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 5, 2026.

It’s typically best to fly out from Chicago to South Carolina in the evening. Doing so could potentially save you 18% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Chicago to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Chicago to South Carolina. Price data was last updated on May 2, 2026.

Travelers seeking maximum savings on their Chicago to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago to South Carolina

Explore weekly flight availability from Chicago to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 5, 2026.

The most flights from CHI to USSC are scheduled on a Monday (26 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (10 on average).

How much does it cost to fly round-trip from Chicago to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 5, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Chicago to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,305 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
7.9
Good
4,305 reviews
Southwest
7.9
Good
4,305 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,460 reviews
Southwest
7.9
Good
4,305 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,683 reviews
Southwest
7.9
Good
4,305 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,667 reviews
Southwest
7.9
Good
4,305 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Spirit Airlines
6.3
Okay
8,634 reviews
Southwest
7.9
Good
4,305 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Chicago to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago to South Carolina?

    Southwest, United Airlines, and Delta can get you from Chicago to South Carolina in just under 1h 55m. Your travel time can differ by up to 2h 08m. There are 583 mi between Chicago and South Carolina. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Chicago to South Carolina one-way?

    For one-way options, check prices for Volaris. According to our data, you can fly for as low as $48. Users have also found prices from $64 and $87 on Spirit Airlines and Viva, respectively.

  • What are the most popular routes from Chicago to South Carolina?

    When deciding which route to take from Chicago to South Carolina consider Chicago O'Hare Intl - Charleston, Chicago O'Hare Intl - Charlotte Douglas or Chicago O'Hare Intl - Savannah/Hilton Head as they are the most popular.

  • What are the most reliable airlines from Chicago to South Carolina?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Chicago to South Carolina on time: Republic Airways (81%), Envoy Air (78%), United Airlines (75%).

  • What are the cheapest flights from Chicago to South Carolina?

    On average you can expect to pay $485 for a flight from Chicago to South Carolina. The cheapest flight overall is $118 while the most popular route, (Chicago O'Hare Intl - Charleston) is currently priced at $237.

  • Can I find deals for flights from Chicago to South Carolina that include hotel bookings?

    Yes. In addition to deals on Chicago to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to South Carolina.

  • Can I find deals for business class flights from Chicago to South Carolina?

    Yes. Cheapflights offers flight deals from Chicago to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $50). Flying from Chicago to South Carolina in October is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Chicago to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Chicago to South Carolina

Discover the top 5 airlines that operate flights from Chicago to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$52Average$170FlexibilityNo cancel feeOn-time65%
DeltaCheapest$146Average$274FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$153Average$385FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$197Average$380FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$202Average$363FlexibilityNo cancel feeOn-time71%

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