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$94+ Cheap flights from South Carolina to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CHI
Aug 23 — Aug 301
Sun 8/23
Sun 8/30
1 adult, Economy
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Cheap flight deals from South Carolina to Chicago

Cheapest flights from South Carolina to Chicago
Explore the most affordable flight options available from South Carolina to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:19 pm
SAV
-
ORD
1 stop25h 31m
Multiple Airlines
Wed 8/268:05 am
ORD
-
SAV
1 stop8h 50m
Multiple Airlines
Deal found 7/22$184
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:04 pm
MYR
-
ORD
Nonstop2h 33m
American Airlines
Mon 9/78:15 am
ORD
-
MYR
Nonstop2h 19m
American Airlines
Deal found 7/21$197
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:58 pm
MYR
-
ORD
1 stop6h 01m
Delta
Tue 10/63:40 pm
ORD
-
MYR
1 stop6h 08m
Delta
Deal found 7/22$217
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:00 pm
MYR
-
ORD
Nonstop2h 36m
United Airlines
Tue 10/2011:55 am
ORD
-
MYR
Nonstop2h 21m
United Airlines
Deal found 7/22$218
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:33 am
MYR
-
ORD
1 stop5h 44m
Delta
Thu 8/205:30 am
ORD
-
MYR
1 stop4h 17m
Delta
Deal found 7/21$227
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:53 pm
MYR
-
ORD
1 stop21h 57m
Multiple Airlines
Thu 9/247:45 am
ORD
-
MYR
1 stop23h 13m
Multiple Airlines
Deal found 7/24$228
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:59 pm
SAV
-
ORD
Nonstop2h 36m
United Airlines
Sat 9/55:55 pm
ORD
-
SAV
Nonstop2h 24m
United Airlines
Deal found 7/22$237
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:04 pm
MYR
-
ORD
Nonstop2h 33m
American Airlines
Mon 8/178:15 am
ORD
-
MYR
Nonstop2h 19m
American Airlines
Deal found 7/23$238
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:07 pm
SAV
-
ORD
Nonstop2h 36m
American Airlines
Sun 9/68:00 am
ORD
-
SAV
Nonstop2h 22m
American Airlines
Deal found 7/20$238
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:27 am
MYR
-
ORD
1 stop29h 14m
Frontier
Sun 9/136:30 am
ORD
-
MYR
2 stops11h 54m
Frontier
Deal found 7/19$240
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:23 pm
SAV
-
ORD
1 stop7h 52m
United Airlines
Tue 8/257:10 am
ORD
-
SAV
Nonstop2h 30m
United Airlines
Deal found 7/21$243
This Mytrip deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:07 am
SAV
-
ORD
1 stop8h 11m
Avelo Airlines
Wed 9/166:10 pm
ORD
-
SAV
1 stop14h 12m
Avelo Airlines
Deal found 7/22$245

Find flight deals from South Carolina to Chicago

Keep the following information in mind while searching for South Carolina to Chicago flight deals. Data was last updated July 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$184
(Kiwi.com)

One-way from

$94
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$417

Good round-trip deal

$308 or less

Good one-way deal

$212 or less
Provider with most accurate pricing for Myrtle Beach Intl-Chicago (CHI) flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Chicago (CHI) flights.
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From South Carolina to Chicago (CHI)
Search Deals
One-way flight from South Carolina to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($19 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals
Price to beat on a round-trip flight from South Carolina to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from South Carolina to Chicago (CHI).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
Use the filters below to find and compare flights from South Carolina to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SavannahChicago

SAV - ORD

SAVORD

Savannah/Hilton Head

Thu 10/8

12:46 pm-2:21 pm

Nonstop2h 35m

Chicago O'Hare Intl

Mon 10/12

7:30 am-11:00 am

Nonstop2h 30m

$237

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Tue 9/1

8:05 am-9:23 am

Nonstop2h 18m

Chicago O'Hare Intl

Thu 9/10

5:45 pm-9:00 pm

Nonstop2h 15m

$259

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 8/20

1:05 pm-4:15 pm

1 stop4h 10m

Chicago Midway

Mon 8/24

8:00 am-11:10 am

Nonstop2h 10m

$269

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 8/13

9:23 am-12:54 pm

1 stop4h 31m

Chicago O'Hare Intl

Tue 8/18

8:54 am-12:03 pm

Nonstop2h 09m

$269

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Tue 8/18

11:10 am-4:55 pm

1 stop6h 45m

Chicago Midway

Tue 8/25

8:45 am-11:55 am

Nonstop2h 10m

$269

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Tue 9/8

6:35 pm-7:35 pm

Nonstop2h 00m

Chicago Midway

Tue 9/15

9:50 am-5:55 pm

1 stop7h 05m

$269

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Tue 9/22

12:40 pm-2:05 pm

Nonstop2h 25m

Chicago O'Hare Intl

Tue 9/22

6:15 pm-11:59 pm

1 stop4h 44m

$269

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Sat 8/15

10:17 am-11:37 am

Nonstop2h 20m

Chicago O'Hare Intl

Tue 8/18

6:30 am-9:36 am

Nonstop2h 06m

$269

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 10/8

10:40 am-7:15 pm

1 stop9h 35m

Chicago Midway

Mon 10/12

7:45 am-10:35 am

Nonstop1h 50m

$275
Quickest round-trip

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Tue 8/18

8:05 am-9:00 am

Nonstop1h 55m

Chicago Midway

Wed 8/19

8:45 am-11:55 am

Nonstop2h 10m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/22

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from South Carolina to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Chicago

What is the cheapest month to book a flight from South Carolina to Chicago?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $316). Flying from South Carolina to Chicago in June is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to CHI?

Find hourly flight availability from South Carolina to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 24, 2026.

When flying from South Carolina to Chicago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 17% versus a flight at noon.

Weekly flight availability from South Carolina to Chicago

Explore weekly flight availability from South Carolina to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 24, 2026.

The most flights from USSC to CHI are scheduled on a Thursday (24 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (15 on average).

How much does it cost to fly round-trip from South Carolina to Chicago?

Airfare is below average for this route at the moment.
South Carolina to Chicago flights typically cost between $292 and $451 in September.
The cheapest round-trip price found within the last 5 days was $281 on Multiple Airlines (Sep 13-Sep 16).

How far ahead should I book a flight from South Carolina to Chicago?

Booking 76 days in advance of your planned departure date is, on average, the best time to get cheap flights from South Carolina to Chicago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest day to fly from South Carolina to Chicago?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Chicago. Price data was last updated on July 18, 2026.

Travelers seeking maximum savings on their South Carolina to Chicago flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Chicago?

    United Airlines, American Airlines, and Southwest can get you from South Carolina to Chicago in just under 1h 55m. Your travel time will be generally consistent. Airlines will cover a distance of 583 mi. Most flights are nonstop.

  • What are the cheapest airlines to fly from South Carolina to Chicago one-way?

    $107 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Volaris and Viva, with prices starting from $126 and $128, respectively.

  • What are the most popular routes from South Carolina to Chicago?

    While some choose either Charlotte Douglas - Chicago Midway or Columbia Metropolitan - Chicago O'Hare Intl, Charlotte Douglas - Chicago O'Hare Intl is the most popular route from South Carolina to Chicago.

  • What are the most reliable airlines from South Carolina to Chicago?

    Consider Qatar Airways (88%), American Airlines (80%) or Alaska Airlines (76%) when booking your flight. These represent the most reliable airlines when flying from South Carolina to Chicago.

  • What are the cheapest flights from South Carolina to Chicago?

    The cheapest flight price from South Carolina to Chicago is $127. On average you can expect to pay $1,759. The most popular route, (Charlotte Douglas - Chicago O'Hare Intl), can usually be booked for $230.

  • Can I find deals for flights from South Carolina to Chicago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Chicago.

  • Can I find deals for business class flights from South Carolina to Chicago?

    Yes. Cheapflights offers flight deals from South Carolina to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Chicago?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $316). Flying from South Carolina to Chicago in June is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Benton Harbor
Lansing
Merrillville
Valparaiso
Hammond
Saint Joseph
Porter

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Alternative routes for South Carolina to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to Chicago

Discover the top 4 airlines that operate flights from South Carolina to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$107Average$331FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$190Average$363FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$202Average$380FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$203Average$367FlexibilityNo cancel feeOn-time71%

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