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$69+ Cheap flights from South Carolina to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CHI
abr. 29 — may. 61
mié. 4/29
mié. 5/6
1 adult, Economy
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Cheap flight deals from South Carolina to Chicago

Cheapest flights from South Carolina to Chicago
Explore the most affordable flight options available from South Carolina to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 30, 2026.

This Frontier deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/234:19 pm
CLT
-
ORD
Nonstop2h 34m
Frontier
jue. 4/3012:16 pm
ORD
-
CLT
Nonstop2h 08m
Frontier
Deal found 3/29$119
This Flightnetwork deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/273:12 pm
CLT
-
ORD
1 stop25h 05m
Frontier
lun. 5/412:37 pm
ORD
-
CLT
Nonstop2h 08m
Frontier
Deal found 3/28$120
This Trip.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/249:54 pm
CLT
-
ORD
1 stop12h 42m
Multiple Airlines
lun. 4/2712:37 pm
ORD
-
CLT
Nonstop2h 08m
Multiple Airlines
Deal found 3/27$121
This Trip.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/1610:24 pm
CLT
-
ORD
Nonstop2h 20m
Frontier
dom. 4/192:00 pm
ORD
-
CLT
Nonstop2h 16m
Frontier
Deal found 3/26$122
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 4/189:32 pm
CLT
-
ORD
1 stop12h 33m
Multiple Airlines
vie. 4/2412:37 pm
ORD
-
CLT
Nonstop2h 08m
Multiple Airlines
Deal found 3/29$123
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/179:26 pm
CLT
-
ORD
Nonstop2h 27m
Frontier
dom. 4/192:00 pm
ORD
-
CLT
Nonstop2h 16m
Frontier
Deal found 3/27$124
This CheapOair deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/34:41 pm
CLT
-
ORD
Nonstop2h 34m
Frontier
mar. 5/53:55 pm
ORD
-
CLT
1 stop23h 48m
Frontier
Deal found 3/28$125
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/234:19 pm
CLT
-
ORD
Nonstop2h 34m
Frontier
dom. 4/268:00 am
ORD
-
CLT
1 stop10h 21m
Frontier
Deal found 3/26$126
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/244:40 pm
CLT
-
ORD
Nonstop2h 34m
Multiple Airlines
mié. 4/292:09 pm
ORD
-
CLT
1 stop6h 52m
Multiple Airlines
Deal found 3/26$127
This Frontier deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/244:40 pm
CLT
-
ORD
Nonstop2h 34m
Frontier
lun. 4/2712:37 pm
ORD
-
CLT
Nonstop2h 08m
Frontier
Deal found 3/29$128
This CheapOair deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/2912:50 pm
CLT
-
ORD
1 stop12h 34m
Multiple Airlines
lun. 5/412:37 pm
ORD
-
CLT
Nonstop2h 08m
Multiple Airlines
Deal found 3/28$129
This Frontier deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/298:09 pm
CLT
-
MDW
1 stop12h 12m
Frontier
sáb. 5/29:14 am
MDW
-
CLT
1 stop6h 21m
Frontier
Deal found 3/29$140

Find flight deals from South Carolina to Chicago

Keep the following information in mind while searching for South Carolina to Chicago flight deals. Data was last updated marzo 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$119
(Frontier)

One-way from

$69
(Super.com)

Popular in

March

Cheapest in

August

Average price

$479

Good round-trip deal

$293 or less

Good one-way deal

$148 or less
Provider with most accurate pricing for Myrtle Beach Intl-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Chicago (CHI) flights.
Search Deals
From South Carolina to Chicago (CHI)
Search Deals
One-way flight from South Carolina to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from South Carolina to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from South Carolina to Chicago (CHI).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 30, 2026.
Use the filters below to find and compare flights from South Carolina to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

mar. 4/21

6:15 am-7:33 am

Nonstop2h 18m

Chicago O'Hare Intl

mar. 4/28

8:45 am-2:05 pm

1 stop4h 20m

$177
Quickest round-trip

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

sáb. 4/25

8:10 am-9:10 am

Nonstop2h 00m

Chicago Midway

sáb. 5/2

3:40 pm-6:35 pm

Nonstop1h 55m

$201

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

mar. 5/26

5:35 am-8:39 am

1 stop4h 04m

Chicago O'Hare Intl

jue. 6/4

2:59 pm-9:59 pm

1 stop6h 00m

$204

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

mié. 4/15

5:30 am-8:40 am

1 stop4h 10m

Chicago O'Hare Intl

jue. 4/23

5:15 am-11:11 am

1 stop4h 56m

$222

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

mar. 5/26

6:45 am-12:50 pm

1 stop7h 05m

Chicago O'Hare Intl

vie. 5/29

2:40 pm-10:15 pm

1 stop6h 35m

$225

GreenvilleChicago

GSP - MDW

GSPMDW

Greenville

vie. 4/17

6:25 pm-9:00 pm

1 stop3h 35m

Chicago Midway

mié. 4/22

4:50 pm-9:40 pm

1 stop3h 50m

$229

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

vie. 5/15

8:30 pm-11:30 pm

1 stop4h 00m

Chicago Midway

lun. 5/18

7:05 pm-10:00 pm

Nonstop1h 55m

$247

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

jue. 4/23

12:36 pm-2:26 pm

Nonstop2h 50m

Chicago O'Hare Intl

lun. 4/27

4:17 pm-10:24 pm

1 stop5h 07m

$253

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

mar. 4/14

6:45 am-12:50 pm

1 stop7h 05m

Chicago O'Hare Intl

vie. 4/17

2:40 pm-10:15 pm

1 stop6h 35m

$256

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

sáb. 6/6

7:50 am-8:45 am

Nonstop1h 55m

Chicago Midway

mar. 6/9

8:00 am-11:10 am

Nonstop2h 10m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Chicago

What is the cheapest month to book a flight from South Carolina to Chicago?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $98). Flying from South Carolina to Chicago in March is currently the most expensive (average of $209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to CHI?

Find hourly flight availability from South Carolina to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated marzo 30, 2026.

When flying from South Carolina to Chicago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 21% versus a flight at noon.

What is the cheapest day to fly from South Carolina to Chicago?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Chicago. Price data was last updated on March 28, 2026.

Travelers seeking maximum savings on their South Carolina to Chicago flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from South Carolina to Chicago

Explore weekly flight availability from South Carolina to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated marzo 30, 2026.

The most flights from USSC to CHI are scheduled on a Monday (26 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (11 on average).

How much does it cost to fly round-trip from South Carolina to Chicago?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Chicago?

    United Airlines, Southwest, and Delta can get you from South Carolina to Chicago in just under 2h. Your travel time can differ by up to 2h 04m. Airlines will cover a distance of 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Chicago one-way?

    $112 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Spirit Airlines and Volaris, with prices starting from $113 and $119, respectively.

  • What are the most popular routes from South Carolina to Chicago?

    While some choose either Greenville - Chicago O'Hare Intl or Charleston - Chicago O'Hare Intl, Charlotte Douglas - Chicago O'Hare Intl is the most popular route from South Carolina to Chicago.

  • What are the most reliable airlines from South Carolina to Chicago?

    Consider Alaska Airlines (79%), Envoy Air (79%) or Qatar Airways (77%) when booking your flight. These represent the most reliable airlines when flying from South Carolina to Chicago.

  • What are the cheapest flights from South Carolina to Chicago?

    The cheapest flight price from South Carolina to Chicago is $145. On average you can expect to pay $1,070. The most popular route, (Charlotte Douglas - Chicago O'Hare Intl), can usually be booked for $115.

  • Can I find deals for flights from South Carolina to Chicago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Chicago.

  • Can I find deals for business class flights from South Carolina to Chicago?

    Yes. Cheapflights offers flight deals from South Carolina to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Chicago?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Chicago (average of $98). Flying from South Carolina to Chicago in March is currently the most expensive (average of $209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lansing
Merrillville
Hammond
Porter
Benton Harbor

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Alternative routes for South Carolina to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Chicago

Discover the top 5 airlines that operate flights from South Carolina to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$60Average$182FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$135Average$341FlexibilityNo cancel feeOn-time71%
DeltaCheapest$156Average$326FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$178Average$361FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$190Average$369FlexibilityNo cancel feeOn-time63%

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