How long is the flight from Santiago to Chicago O'Hare Intl Airport?

Delta can get you from Santiago to Chicago O'Hare Intl Airport in just under 17h 04m. Your travel time can differ by up to . There are 5316 mi between Santiago and Chicago O'Hare Intl Airport.

What are the cheapest airlines flying from Santiago to Chicago O'Hare Intl Airport round-trip?

Flying on Copa Airlines is currently your cheapest option to Chicago O'Hare Intl Airport, with prices starting at $501. Additional round-trip tickets that might be worth considering are offered by Delta and LATAM Airlines, with the lowest prices starting at $504 and $506, respectively. Copa Airlines is priced at 32% lower than the current average price of a flight leaving 3 months from now.

What is the cheapest day to fly from Santiago to Chicago O'Hare Intl Airport?

Travelers seeking maximum savings on their Santiago to Chicago O'Hare Intl Airport flight should consider departing on Wednesday mornings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Chicago O'Hare Intl Airport ranges from 1.7 - 4.9 inches per month. August is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Chicago O'Hare Intl Airport when rainfall is around 1.7 in.

If weather is an important factor for your trip to Chicago O'Hare Intl Airport, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What are the most popular airlines that fly from Santiago to Chicago O'Hare Intl Airport?

When booking a flight from Santiago to Chicago O'Hare Intl Airport, you may want to consider flying on American Airlines, Avianca or Copa Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from Santiago to Chicago O'Hare Intl Airport?

Leaving on a Tuesday is a viable option for saving on travel. Heavily demanded days of the week can typically drive up the prices you see. Booking your travel for a less competitive day can save up to 21% on the overall cost on flights from Santiago to Chicago O'Hare Intl Airport.

What is the cheapest month to fly from Santiago to Chicago O'Hare Intl Airport?

April is one of the best times of the year to fly to Chicago O'Hare Intl Airport from Santiago. Prices for April average $702 per person but you can even find prices for as low as $499. The most expensive prices can be found in the month of July. Opting for a April flight can save you 14% on your journey compared to booking in July

What is the cheapest time of day to fly from SCL to ORD?

When flying from Santiago to Chicago O'Hare Intl Airport, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 34% versus a flight in the afternoon.

What airport do you fly from for flights from Santiago to Chicago O'Hare Intl?

Most people fly from Santiago Arturo Merino Benitez (SCL) if they book a flight from Santiago to Chicago O'Hare Intl. On average, Arturo Merino Benitez has 0 outbound flights to Chicago O'Hare Intl per day from 5 airlines. Santiago Arturo Merino Benitez is conveniently located just 8.4 mi from Santiago’s city center.

Can I find deals for flights from Santiago to O'Hare Intl that include hotel bookings?

Yes. In addition to deals on Santiago to O'Hare Intl flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santiago to O'Hare Intl?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to O'Hare Intl.

Can I find deals for business class flights from Santiago to O'Hare Intl?

Yes. Cheapflights offers flight deals from Santiago to O'Hare Intl by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$254+ Flights from Santiago to Chicago O'Hare Intl Airport

Q: How far in advance should I book a flight from Santiago to Chicago O'Hare Intl Airport?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 61 days in advance, which can save you up to 48% on flights from Santiago to Chicago O'Hare Intl Airport compared to booking the week you need them. Waiting 61 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $487. For sooner than that we have options available in the next 3 days from $503.

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Chicago O'Hare Intl are usually found in March or April, booked 60 days in advance, depart on a Wednesday or Thursday and return on a Tuesday

Cheap flight deals from Santiago to O'Hare Intl

Round-trip from	$599 (Kiwi.com)
One-way from	$254 (Kiwi.com)
Popular in	September
Cheapest in	March
Average price	$913

From Santiago Arturo Merino Benitez to Chicago O'Hare Intl

Search Deals

One-way flight from Santiago Arturo Merino Benitez to Chicago O'Hare Intl

Search Deals

Highest demand for flights based on searches. 5% potential increase in price ($47 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

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Find flight deals from Santiago to O'Hare Intl

Cheapest flights from Santiago to O'Hare Intl
Explore the most affordable flight options available from Santiago to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Tue 9/3011:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Tue 10/76:18 pmORD - SCL

2 stops32h 57mMultiple Airlines

Deal found 9/9

$553

Wed 10/111:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Tue 10/76:18 pmORD - SCL

2 stops32h 57mMultiple Airlines

Deal found 9/9

$562

Fri 9/2611:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Wed 10/110:27 amORD - SCL

2 stops33h 48mMultiple Airlines

Deal found 9/9

$588

Wed 9/2411:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Wed 10/110:27 amORD - SCL

2 stops33h 48mMultiple Airlines

Deal found 9/9

$595

Mon 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Tue 9/3010:27 amORD - SCL

2 stops33h 43mMultiple Airlines

Deal found 9/9

$598

Wed 9/2411:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Tue 9/3010:27 amORD - SCL

2 stops33h 43mMultiple Airlines

Deal found 9/10

$599

Fri 9/2611:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Mon 9/2910:27 amORD - SCL

2 stops26h 18mMultiple Airlines

Deal found 9/9

$602

Tue 9/3011:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Mon 10/69:06 pmORD - SCL

2 stops28h 29mMultiple Airlines

Deal found 9/9

$604

Mon 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Mon 10/69:06 pmORD - SCL

2 stops28h 29mMultiple Airlines

Deal found 9/9

$607

Tue 9/3011:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Fri 10/1010:27 amORD - SCL

3 stops23h 53mMultiple Airlines

Deal found 9/9

$608

Tue 9/2311:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Tue 9/3010:27 amORD - SCL

2 stops33h 48mMultiple Airlines

Deal found 9/10

$611

Wed 10/111:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Mon 10/69:06 pmORD - SCL

2 stops28h 29mMultiple Airlines

Deal found 9/9

$612

Best flights from Santiago to O'Hare Intl
Discover carefully curated flight deals from Santiago to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2025.

Fri 10/38:50 amSCL - ORD

2 stops17h 04mDelta

Thu 10/166:45 amORD - SCL

1 stop22h 15mDelta

Deal found 9/9

$644

Sat 10/410:55 pmSCL - ORD

2 stops23h 25mDelta

Mon 10/137:59 pmORD - SCL

1 stop33h 01mDelta

Deal found 9/9

$644

Wed 10/110:55 pmSCL - ORD

1 stop15h 21mDelta

Fri 10/1711:23 amORD - SCL

2 stops17h 22mDelta

Deal found 9/9

$644

Thu 10/28:15 amSCL - ORD

2 stops17h 39mDelta

Tue 10/141:26 pmORD - SCL

1 stop15h 34mDelta

Deal found 9/9

$644

Fri 10/38:15 amSCL - ORD

2 stops17h 39mDelta

Tue 10/141:26 pmORD - SCL

1 stop15h 34mDelta

Deal found 9/9

$644

Thu 10/29:40 pmSCL - ORD

1 stop16h 44mDelta

Fri 10/1711:23 amORD - SCL

2 stops17h 22mDelta

Deal found 9/9

$644

Wed 10/19:40 pmSCL - ORD

1 stop16h 44mDelta

Mon 10/136:45 amORD - SCL

2 stops21h 00mDelta

Deal found 9/9

$644

Mon 9/299:40 pmSCL - ORD

1 stop17h 21mDelta

Sat 10/181:25 pmORD - SCL

2 stops15h 35mDelta

Deal found 9/9

$644

Thu 10/29:40 pmSCL - ORD

1 stop16h 44mDelta

Sun 10/1211:23 amORD - SCL

1 stop17h 37mDelta

Deal found 9/9

$644

Tue 9/309:40 pmSCL - ORD

1 stop14h 30mDelta

Sat 10/186:45 amORD - SCL

1 stop22h 15mDelta

Deal found 9/9

$644

Thu 10/29:40 pmSCL - ORD

1 stop14h 30mDelta

Thu 10/166:45 amORD - SCL

1 stop22h 15mDelta

Deal found 9/9

$644

Mon 9/299:40 pmSCL - ORD

1 stop14h 30mDelta

Sun 10/129:42 amORD - SCL

1 stop19h 18mDelta

Deal found 9/9

$644

Last-minute flights from Santiago to O'Hare Intl
Discover last-minute flight deals from Santiago to O'Hare Intl. Data last updated September 11, 2025 and is based on user searches.

Mon 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Tue 9/3010:27 amORD - SCL

2 stops33h 43mMultiple Airlines

Deal found 9/9

$598

Mon 9/2211:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Mon 10/69:06 pmORD - SCL

2 stops28h 29mMultiple Airlines

Deal found 9/9

$607

Tue 9/2311:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Tue 9/3010:27 amORD - SCL

2 stops33h 48mMultiple Airlines

Deal found 9/10

$611

Wed 9/2411:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Wed 10/110:27 amORD - SCL

2 stops33h 48mMultiple Airlines

Deal found 9/9

$595

Wed 9/2411:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Tue 9/3010:27 amORD - SCL

2 stops33h 43mMultiple Airlines

Deal found 9/10

$599

Fri 9/2611:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Wed 10/110:27 amORD - SCL

2 stops33h 48mMultiple Airlines

Deal found 9/9

$588

Fri 9/2611:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Mon 9/2910:27 amORD - SCL

2 stops26h 18mMultiple Airlines

Deal found 9/9

$602

Tue 9/3011:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Tue 10/76:18 pmORD - SCL

2 stops32h 57mMultiple Airlines

Deal found 9/9

$553

Tue 9/3011:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Mon 10/69:06 pmORD - SCL

2 stops28h 29mMultiple Airlines

Deal found 9/9

$604

Tue 9/3011:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Fri 10/1010:27 amORD - SCL

3 stops23h 53mMultiple Airlines

Deal found 9/9

$608

Wed 10/111:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Tue 10/76:18 pmORD - SCL

2 stops32h 57mMultiple Airlines

Deal found 9/9

$562

Wed 10/111:00 amSCL - ORD

1 stop24h 18mMultiple Airlines

Mon 10/69:06 pmORD - SCL

2 stops28h 29mMultiple Airlines

Deal found 9/9

$612

One-way flights from Santiago to O'Hare Intl
Search for one-way flight options from Santiago to O'Hare Intl. Find affordable one-way fares based on user searches. Data last updated September 11, 2025.

Tue 10/143:30 pmSCL - ORD

2 stops47h 45mMultiple Airlines

Deal found 9/10

$254

Thu 9/2512:55 amSCL - ORD

2 stops35h 22mMultiple Airlines

Deal found 9/9

$263

Wed 11/121:35 amSCL - ORD

2 stops39h 03mMultiple Airlines

Deal found 9/11

$271

Sat 9/273:30 pmSCL - ORD

2 stops44h 48mMultiple Airlines

Deal found 9/9

$274

Thu 10/163:30 pmSCL - ORD

3 stops36h 01mMultiple Airlines

Deal found 9/10

$294

Sat 10/253:30 pmSCL - ORD

3 stops50h 19mMultiple Airlines

Deal found 9/11

$295

Mon 9/223:30 pmSCL - ORD

2 stops19h 48mMultiple Airlines

Deal found 9/9

$296

Mon 10/138:45 pmSCL - ORD

3 stops53h 00mMultiple Airlines

Deal found 9/11

$300

Wed 9/243:30 pmSCL - ORD

2 stops19h 48mMultiple Airlines

Deal found 9/9

$303

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Fri 10/3

8:50 am-11:54 pm

2 stops17h 04m

Chicago O'Hare Intl

Thu 10/16

6:45 am-7:00 am

1 stop22h 15m

$644

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Sat 10/4

10:55 pm-8:20 pm

2 stops23h 25m

Chicago O'Hare Intl

Mon 10/13

7:59 pm-7:00 am

1 stop33h 01m

$644

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Wed 10/1

10:55 pm-12:16 pm

1 stop15h 21m

Chicago O'Hare Intl

Fri 10/17

11:23 am-6:45 am

2 stops17h 22m

$644

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Thu 10/2

8:15 am-11:54 pm

2 stops17h 39m

Chicago O'Hare Intl

Tue 10/14

1:26 pm-7:00 am

1 stop15h 34m

$644

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Fri 10/3

8:15 am-11:54 pm

2 stops17h 39m

Chicago O'Hare Intl

Tue 10/14

1:26 pm-7:00 am

1 stop15h 34m

$644

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Thu 10/2

9:40 pm-12:24 pm

1 stop16h 44m

Chicago O'Hare Intl

Fri 10/17

11:23 am-6:45 am

2 stops17h 22m

$644

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Wed 10/1

9:40 pm-12:24 pm

1 stop16h 44m

Chicago O'Hare Intl

Mon 10/13

6:45 am-5:45 am

2 stops21h 00m

$644

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Mon 9/29

9:40 pm-1:01 pm

1 stop17h 21m

Chicago O'Hare Intl

Sat 10/18

1:25 pm-7:00 am

2 stops15h 35m

$644

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Thu 10/2

9:40 pm-12:24 pm

1 stop16h 44m

Chicago O'Hare Intl

Sun 10/12

11:23 am-7:00 am

1 stop17h 37m

$644

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Tue 9/30

9:40 pm-10:10 am

1 stop14h 30m

Chicago O'Hare Intl

Sat 10/18

6:45 am-7:00 am

1 stop22h 15m

$644

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 21 results

Best time to book a flight from Santiago to O'Hare Intl

Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Santiago with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Chicago O'Hare Intl Airport

How far ahead should I book a flight from Santiago to Chicago O'Hare Intl Airport?

The best time to book flights from Santiago to Chicago O'Hare Intl Airport is 60 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Chicago O'Hare Intl Airport?

Currently, August is the cheapest month in which you can book a flight from Santiago to Chicago O'Hare Intl Airport (average of $245). Flying from Santiago to Chicago O'Hare Intl Airport in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing O'Hare Intl

Read reviews from past customers who have flown Delta, Copa Airlines, and LATAM Airlines from Santiago to Chicago O'Hare Intl Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

6.0

Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Delta

8.0

Very good

7,960 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

6.0

Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Copa Airlines

7.6

Good

1,531 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

6.0

Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

LATAM Airlines

7.5

Good

1,847 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

6.0

Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

6.0

Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Avianca

6.7

Okay

2,436 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

6.0

Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

What airport do you fly from for flights from Santiago to Chicago O'Hare Intl?
Most people fly from Santiago Arturo Merino Benitez (SCL) if they book a flight from Santiago to Chicago O'Hare Intl. On average, Arturo Merino Benitez has 0 outbound flights to Chicago O'Hare Intl per day from 5 airlines. Santiago Arturo Merino Benitez is conveniently located just 8.4 mi from Santiago’s city center.
How long is the flight from Santiago to Chicago O'Hare Intl Airport?
Delta can get you from Santiago to Chicago O'Hare Intl Airport in just under 17h 04m. Your travel time can differ by up to . There are 5316 mi between Santiago and Chicago O'Hare Intl Airport.
What are the cheapest airlines flying from Santiago to Chicago O'Hare Intl Airport round-trip?
Flying on Copa Airlines is currently your cheapest option to Chicago O'Hare Intl Airport, with prices starting at $501. Additional round-trip tickets that might be worth considering are offered by Delta and LATAM Airlines, with the lowest prices starting at $504 and $506, respectively. Copa Airlines is priced at 32% lower than the current average price of a flight leaving 3 months from now.
Can I find deals for flights from Santiago to O'Hare Intl that include hotel bookings?
Yes. In addition to deals on Santiago to O'Hare Intl flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santiago to O'Hare Intl?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to O'Hare Intl.
Can I find deals for business class flights from Santiago to O'Hare Intl?
Yes. Cheapflights offers flight deals from Santiago to O'Hare Intl by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santiago to Chicago O'Hare Intl Airport?
Currently, August is the cheapest month in which you can book a flight from Santiago to Chicago O'Hare Intl Airport (average of $245). Flying from Santiago to Chicago O'Hare Intl Airport in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 5 airlines flying from Santiago to O'Hare Intl

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$501	Average$731	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$504	Average$784	FlexibilityNo cancel fee	On-timeN/A
LATAM Airlines	Cheapest$506	Average$770	FlexibilityNo cancel fee	On-time81%
Avianca	Cheapest$519	Average$675	FlexibilityNo cancel fee	On-time71%
American Airlines	Cheapest$753	Average$945	FlexibilityNo cancel fee	On-time71%

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$254+ Cheap flights from Santiago (SCL) to O'Hare Intl (ORD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santiago to O'Hare Intl with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Chicago O'Hare Intl are usually found in March or April, booked 60 days in advance, depart on a Wednesday or Thursday and return on a Tuesday

Cheap flight deals from Santiago to O'Hare Intl

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santiago to O'Hare Intl

Cheapest flights from Santiago to O'Hare IntlExplore the most affordable flight options available from Santiago to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Explore the most affordable flight options available from Santiago to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to Chicago O'Hare Intl Airport that are best for you.

Best time to book a flight from Santiago to O'Hare Intl

Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Santiago with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Chicago O'Hare Intl Airport

How far ahead should I book a flight from Santiago to Chicago O'Hare Intl Airport?

What is the cheapest month to book a flight from Santiago to Chicago O'Hare Intl Airport?

Reviews of airlines servicing O'Hare Intl

Read reviews from past customers who have flown Delta, Copa Airlines, and LATAM Airlines from Santiago to Chicago O'Hare Intl Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santiago to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

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Cheapest flights from Santiago to O'Hare Intl
Explore the most affordable flight options available from Santiago to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.