$323+ Cheap flights from Santiago (SCL) to Chicago (CHI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — CHI
Aug 1 — Aug 81
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to Chicago with Cheapflights
1. Tell us where you want to go
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Cheapest flights from Santiago to ChicagoExplore the most affordable flight options available from Santiago to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2026.
Explore the most affordable flight options available from Santiago to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2026.
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:40 am
SCL
- ORD
1 stop15h 40m
Avianca
Wed 8/1911:20 pm
ORD
- SCL
1 stop13h 55m
Avianca
Deal found 7/2![Avianca logo]()
$617
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1011:00 pm
SCL
- ORD
2 stops20h 49m
Delta
Mon 8/311:59 pm
ORD
- SCL
2 stops16h 16m
Delta
Deal found 7/2![Delta logo]()
$618
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:55 pm
SCL
- MDW
2 stops20h 38m
Delta
Wed 8/1912:46 pm
MDW
- SCL
1 stop17h 29m
Delta
Deal found 7/2![Delta logo]()
$618
This Copa Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:22 pm
SCL
- ORD
1 stop27h 37m
Copa Airlines
Tue 10/208:01 am
ORD
- SCL
1 stop20h 09m
Copa Airlines
Deal found 7/1![Copa Airlines logo]()
$619
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:55 pm
SCL
- ORD
1 stop23h 57m
Delta
Mon 8/241:50 pm
ORD
- SCL
1 stop16h 25m
Delta
Deal found 7/1![Delta logo]()
$622
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:55 pm
SCL
- MDW
2 stops20h 38m
Delta
Tue 8/185:10 pm
MDW
- SCL
1 stop13h 05m
Delta
Deal found 7/1![Delta logo]()
$622
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:55 pm
SCL
- ORD
2 stops20h 34m
Delta
Tue 7/2811:30 am
ORD
- SCL
2 stops17h 55m
Delta
Deal found 6/29![Delta logo]()
$624
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:30 am
SCL
- MDW
2 stops30h 10m
Delta
Sun 7/126:00 am
MDW
- SCL
1 stop24h 15m
Delta
Deal found 6/28![Delta logo]()
$624
This LATAM Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:40 pm
SCL
- ORD
2 stops18h 27m
LATAM Airlines
Mon 11/165:55 pm
ORD
- SCL
2 stops17h 10m
LATAM Airlines
Deal found 7/1![LATAM Airlines logo]()
$627
This LATAM Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:15 am
SCL
- MDW
2 stops28h 37m
LATAM Airlines
Thu 10/2210:58 am
MDW
- SCL
1 stop19h 17m
LATAM Airlines
Deal found 7/2![LATAM Airlines logo]()
$627
This LATAM Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:55 pm
SCL
- ORD
2 stops29h 55m
LATAM Airlines
Sun 1/245:55 pm
ORD
- SCL
2 stops17h 10m
LATAM Airlines
Deal found 7/1![LATAM Airlines logo]()
$628
This Avianca deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:40 am
SCL
- ORD
1 stop15h 40m
Avianca
Wed 8/1211:20 pm
ORD
- SCL
1 stop13h 55m
Avianca
Deal found 7/1![Avianca logo]()
$630
Best flights from Santiago to ChicagoDiscover carefully curated flight deals from Santiago to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2026.
Discover carefully curated flight deals from Santiago to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2026.
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:55 pm
SCL
- ORD
1 stop19h 06m
Delta
Wed 9/211:22 am
ORD
- SCL
2 stops18h 33m
Delta
Deal found 7/1![Delta logo]()
$618
This Copa Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/283:56 am
SCL
- ORD
1 stop23h 06m
Copa Airlines
Wed 10/218:01 am
ORD
- SCL
1 stop16h 45m
Copa Airlines
Deal found 7/1![Copa Airlines logo]()
$619
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:00 pm
SCL
- ORD
2 stops18h 51m
Delta
Wed 8/193:25 pm
ORD
- SCL
1 stop14h 50m
Delta
Deal found 7/2![Delta logo]()
$618
This Copa Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:06 am
SCL
- ORD
1 stop28h 54m
Copa Airlines
Wed 10/78:01 am
ORD
- SCL
1 stop14h 21m
Copa Airlines
Deal found 6/27![Copa Airlines logo]()
$623
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1011:00 pm
SCL
- ORD
2 stops20h 49m
Delta
Mon 8/311:59 pm
ORD
- SCL
2 stops16h 16m
Delta
Deal found 7/2![Delta logo]()
$618
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:40 pm
SCL
- ORD
2 stops15h 57m
Delta
Sat 10/38:05 am
ORD
- SCL
2 stops20h 50m
Delta
Deal found 7/1![Delta logo]()
$618
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:40 am
SCL
- ORD
2 stops17h 32m
Delta
Tue 10/610:34 am
ORD
- SCL
2 stops18h 21m
Delta
Deal found 7/2![Delta logo]()
$618
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:10 pm
SCL
- MDW
2 stops16h 23m
Delta
Mon 12/710:35 am
MDW
- SCL
2 stops16h 00m
Delta
Deal found 7/2![Delta logo]()
$618
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:00 pm
SCL
- MDW
2 stops17h 44m
Delta
Tue 9/89:29 am
MDW
- SCL
2 stops20h 46m
Delta
Deal found 7/2![Delta logo]()
$618
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:00 pm
SCL
- MDW
2 stops19h 20m
Delta
Sun 10/1110:58 am
MDW
- SCL
1 stop19h 17m
Delta
Deal found 7/2![Delta logo]()
$618
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:40 pm
SCL
- ORD
1 stop28h 13m
Delta
Wed 8/193:25 pm
ORD
- SCL
2 stops14h 30m
Delta
Deal found 7/1![Delta logo]()
$622
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:40 pm
SCL
- MDW
2 stops18h 08m
Delta
Mon 10/129:29 am
MDW
- SCL
2 stops18h 06m
Delta
Deal found 7/1![Delta logo]()
$622
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:40 pm
SCL
- MDW
2 stops18h 08m
Delta
Sun 10/181:28 pm
MDW
- SCL
2 stops16h 47m
Delta
Deal found 7/1![Delta logo]()
$622
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/211:00 pm
SCL
- MDW
2 stops20h 33m
Delta
Thu 9/31:25 pm
MDW
- SCL
2 stops16h 50m
Delta
Deal found 6/29![Delta logo]()
$626
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:40 pm
SCL
- MDW
1 stop17h 15m
Delta
Wed 9/3010:48 am
MDW
- SCL
2 stops18h 07m
Delta
Deal found 6/28![Delta logo]()
$626
Last-minute flights from Santiago to ChicagoDiscover last-minute flight deals from Santiago to Chicago. Data last updated July 2, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to Chicago. Data last updated July 2, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:30 am
SCL
- MDW
2 stops30h 10m
Delta
Fri 7/105:10 pm
MDW
- SCL
2 stops25h 50m
Delta
Deal found 6/28![Delta logo]()
$624
This LATAM Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:30 am
SCL
- MDW
2 stops24h 39m
Multiple Airlines
Sun 7/126:00 am
MDW
- SCL
2 stops22h 35m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$638
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:40 am
SCL
- ORD
2 stops19h 05m
Delta
Tue 10/61:50 pm
ORD
- SCL
1 stop14h 35m
Delta
Deal found 7/2![Delta logo]()
$618
This Copa Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:21 am
SCL
- ORD
1 stop24h 39m
Copa Airlines
Thu 11/57:35 am
ORD
- SCL
1 stop16h 13m
Copa Airlines
Deal found 6/27![Copa Airlines logo]()
$623
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:00 pm
SCL
- ORD
2 stops20h 03m
Delta
Tue 7/2811:30 am
ORD
- SCL
2 stops17h 55m
Delta
Deal found 6/29![Delta logo]()
$624
This Avianca deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:40 am
SCL
- ORD
1 stop15h 40m
Avianca
Tue 10/611:20 pm
ORD
- SCL
1 stop13h 55m
Avianca
Deal found 6/29![Avianca logo]()
$625
This LATAM Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:40 am
SCL
- ORD
2 stops19h 13m
LATAM Airlines
Tue 10/61:15 pm
ORD
- SCL
2 stops15h 40m
LATAM Airlines
Deal found 6/27![LATAM Airlines logo]()
$638
This LATAM Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:00 pm
SCL
- ORD
2 stops27h 33m
LATAM Airlines
Fri 11/65:30 am
ORD
- SCL
2 stops21h 30m
LATAM Airlines
Deal found 6/27![LATAM Airlines logo]()
$633
This LATAM Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:45 pm
SCL
- MDW
2 stops28h 30m
LATAM Airlines
Tue 10/66:00 am
MDW
- SCL
2 stops22h 00m
LATAM Airlines
Deal found 6/27![LATAM Airlines logo]()
$633
This LATAM Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:30 am
SCL
- MDW
3 stops28h 21m
LATAM Airlines
Tue 8/1110:54 am
MDW
- SCL
2 stops25h 26m
LATAM Airlines
Deal found 7/1![LATAM Airlines logo]()
$632
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:55 pm
SCL
- MDW
2 stops20h 38m
Delta
Wed 8/1912:46 pm
MDW
- SCL
1 stop17h 29m
Delta
Deal found 7/2![Delta logo]()
$618
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:55 pm
SCL
- MDW
2 stops20h 38m
Delta
Tue 8/185:10 pm
MDW
- SCL
1 stop13h 05m
Delta
Deal found 7/1![Delta logo]()
$622
One-way flights from Santiago to ChicagoSearch for one-way flight options from Santiago to Chicago. Find affordable one-way fares based on user searches. Data last updated July 2, 2026.
Search for one-way flight options from Santiago to Chicago. Find affordable one-way fares based on user searches. Data last updated July 2, 2026.
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:30 am
SCL
- ORD
1 stop21h 50m
Avianca
Deal found 7/2![Avianca logo]()
$323
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:40 am
SCL
- ORD
1 stop15h 40m
Avianca
Deal found 7/2![Avianca logo]()
$325
This Avianca deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:40 am
SCL
- ORD
1 stop15h 40m
Avianca
Deal found 6/30![Avianca logo]()
$327
This Avianca deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:40 am
SCL
- ORD
1 stop15h 40m
Avianca
Deal found 6/29![Avianca logo]()
$328
This Avianca deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:40 am
SCL
- ORD
1 stop15h 40m
Avianca
Deal found 6/28![Avianca logo]()
$329
This Avianca deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:30 am
SCL
- ORD
1 stop21h 50m
Avianca
Deal found 6/30![Avianca logo]()
$330
This SmartFares deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/74:20 pm
SCL
- ORD
1 stop31h 00m
Avianca
Deal found 7/2![Avianca logo]()
$334
This oojo deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:25 pm
SCL
- ORD
1 stop30h 55m
Avianca
Deal found 7/1![Avianca logo]()
$336
This Copa Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:22 am
SCL
- ORD
1 stop27h 35m
Copa Airlines
Deal found 7/1![Copa Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:20 pm
SCL
- ORD
2 stops22h 12m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:41 am
SCL
- ORD
2 stops44h 06m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:35 am
SCL
- MDW
3 stops43h 23m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$395
Find flight deals from Santiago to Chicago
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $617 (Avianca) |
One-way from | $327 (Avianca) |
Popular in | January |
Cheapest in | March |
Average price | $673 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2026.
Use the filters below to find and compare flights from Santiago to Chicago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Thu 8/20
10:55 pm-5:01 pm
1 stop19h 06m
Chicago O'Hare Intl
Wed 9/2
11:22 am-6:55 am
2 stops18h 33m
$618
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Tue 8/11
11:00 pm-4:51 pm
2 stops18h 51m
Chicago O'Hare Intl
Wed 8/19
3:25 pm-7:15 am
1 stop14h 50m
$618
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Mon 8/10
11:00 pm-6:49 pm
2 stops20h 49m
Chicago O'Hare Intl
Mon 8/31
1:59 pm-7:15 am
2 stops16h 16m
$618
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Fri 9/18
8:40 pm-10:37 am
2 stops15h 57m
Chicago O'Hare Intl
Sat 10/3
8:05 am-6:55 am
2 stops20h 50m
$618
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Tue 7/7
12:40 am-5:12 pm
2 stops17h 32m
Chicago O'Hare Intl
Tue 10/6
10:34 am-6:55 am
2 stops18h 21m
$618
Quickest round-trip
SantiagoChicago
SCL - MDW
SCLMDW
Santiago Arturo Merino Benitez
Tue 12/1
11:10 pm-12:33 pm
2 stops16h 23m
Chicago Midway
Mon 12/7
10:35 am-5:35 am
2 stops16h 00m
$618
SantiagoChicago
SCL - MDW
SCLMDW
Santiago Arturo Merino Benitez
Mon 8/31
11:00 pm-3:44 pm
2 stops17h 44m
Chicago Midway
Tue 9/8
9:29 am-8:15 am
2 stops20h 46m
$618
SantiagoChicago
SCL - MDW
SCLMDW
Santiago Arturo Merino Benitez
Mon 10/5
11:00 pm-4:20 pm
2 stops19h 20m
Chicago Midway
Sun 10/11
10:58 am-8:15 am
1 stop19h 17m
$618
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Mon 9/28
3:56 am-1:02 am
1 stop23h 06m
Chicago O'Hare Intl
Wed 10/21
8:01 am-2:46 am
1 stop16h 45m
$619
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Sun 7/19
8:40 pm-11:53 pm
1 stop28h 13m
Chicago O'Hare Intl
Wed 8/19
3:25 pm-6:55 am
2 stops14h 30m
$622
Showing 1-10 of 32 resultsSorted by cheapest first
Compare providers for flights from Santiago to Chicago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Chicago in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santiago-Chicago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Chicago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Chicago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-Chicago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Santiago with our price prediction graph.
SCL-CHI
SCL-ORD
SCL-MDW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Chicago
SCL-CHI
SCL-ORD
SCL-MDW
What is the cheapest month to book a flight from Santiago to Chicago?
Currently, April is the cheapest month in which you can book a flight from Santiago to Chicago (average of $253). Flying from Santiago to Chicago in August is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to Chicago?
How often are flights from Santiago to Chicago delayed?
About 0% of weekly flights between Santiago and Chicago have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for Santiago to Chicago flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Monday tends to have the lowest number of delays on this route, whereas Tuesday has historically faced a higher average of delays compared to other days of the week.
How far ahead should I book a flight from Santiago to Chicago?
To ensure you get the cheapest price possible for a flight from Santiago to Chicago, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated July 2, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Santiago to Chicago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentRakshith,May 2026
TPE - SEA
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentRakshith,May 2026
TPE - SEA
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentRakshith,May 2026
TPE - SEA
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentRakshith,May 2026
TPE - SEA
Related info for your journey
Find useful and relevant information for your journey from Santiago to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsBenton Harbor
Hammond
Lansing
Merrillville
Valparaiso
Porter
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Alternative routes for Santiago to Chicago
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Other flights to Chicago
Explore flights to Chicago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 2, 2026.
Complete your trip
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Santiago and Chicago flights
Browse other Santiago and Chicago flight options. Last updated on July 2, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on July 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Santiago to Chicago
Discover the top 4 airlines that operate flights from Santiago to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$347 | Average$645 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$583 | Average$814 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$587 | Average$817 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$588 | Average$663 | FlexibilityNo cancel fee | On-time81% |