$361+ Cheap flights from Santiago (SCL) to Chicago (CHI)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/4. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — CHI
Oct 27 — Nov 31
Round-trip
1 adult, Economy
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Cheapest flights from Santiago to ChicagoExplore the most affordable flight options available from Santiago to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 27, 2026.
Explore the most affordable flight options available from Santiago to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 27, 2026.
This FlightHub deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:50 pm -
1 stop15h 56m
Wed 11/410:30 am -
2 stops17h 30m
Deal found 9/25![LATAM Airlines logo]()
$559
This LATAM Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:50 pm -
1 stop20h 30m
Wed 11/118:04 am -
2 stops18h 31m
Deal found 9/24![LATAM Airlines logo]()
$562
This LATAM Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/911:50 pm -
1 stop20h 30m
Mon 11/1610:30 am -
1 stop17h 25m
Deal found 9/25![LATAM Airlines logo]()
$575
This LATAM Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:10 pm -
2 stops18h 39m
Tue 11/178:04 am -
2 stops18h 01m
Deal found 9/26![LATAM Airlines logo]()
$584
This LATAM Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:20 am -
2 stops17h 37m
Tue 10/2710:30 am -
1 stop17h 25m
Deal found 9/25![LATAM Airlines logo]()
$586
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/911:10 pm -
1 stop14h 14m
Mon 11/166:00 am -
2 stops22h 00m
Deal found 9/25![Delta logo]()
$594
This LATAM Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:40 pm -
1 stop15h 23m
Thu 10/226:04 am -
2 stops30h 31m
Deal found 9/25![LATAM Airlines logo]()
$598
This Justfly.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:40 pm -
1 stop15h 23m
Tue 10/135:09 pm -
1 stop13h 06m
Deal found 9/25![LATAM Airlines logo]()
$602
This LATAM Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:55 pm -
2 stops16h 59m
Tue 11/36:04 am -
1 stop22h 36m
Deal found 9/26![LATAM Airlines logo]()
$604
This LATAM Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:10 pm -
1 stop14h 44m
Mon 11/26:04 am -
2 stops22h 26m
Deal found 9/26![LATAM Airlines logo]()
$605
This LATAM Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:05 pm -
2 stops18h 19m
Mon 11/166:00 am -
1 stop22h 40m
Deal found 9/22![LATAM Airlines logo]()
$607
This LATAM Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1511:10 pm -
2 stops21h 51m
Wed 1/2710:35 am -
1 stop18h 05m
Deal found 9/26![Multiple Airlines logo]()
$608
Best flights from Santiago to ChicagoDiscover carefully curated flight deals from Santiago to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 27, 2026.
Discover carefully curated flight deals from Santiago to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 27, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:22 am -
1 stop21h 43m
Mon 11/92:13 pm -
1 stop30h 23m
Deal found 9/24![Copa Airlines logo]()
$591
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:40 pm -
1 stop15h 31m
Tue 10/135:27 am -
1 stop24h 48m
Deal found 9/25![Delta logo]()
$594
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:22 am -
2 stops21h 01m
Sat 10/247:55 pm -
1 stop33h 55m
Deal found 9/22![United Airlines logo]()
$795
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:55 pm -
1 stop19h 25m
Tue 11/310:35 am -
2 stops17h 55m
Deal found 9/25![Delta logo]()
$594
This Copa Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:11 am -
1 stop25h 54m
Mon 11/22:13 pm -
1 stop30h 23m
Deal found 9/26![Copa Airlines logo]()
$638
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:10 pm -
1 stop17h 18m
Wed 11/410:05 am -
2 stops17h 55m
Deal found 9/26![Delta logo]()
$594
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:10 pm -
2 stops17h 49m
Wed 12/911:39 am -
2 stops17h 01m
Deal found 9/26![Delta logo]()
$594
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/111:44 am -
1 stop25h 13m
Mon 10/193:20 pm -
1 stop31h 02m
Deal found 9/24![Copa Airlines logo]()
$713
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2511:00 pm -
2 stops16h 33m
Sun 1/319:30 am -
2 stops19h 10m
Deal found 9/26![Delta logo]()
$594
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:10 pm -
1 stop19h 07m
Wed 11/1111:27 am -
1 stop17h 13m
Deal found 9/24![Delta logo]()
$594
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:40 pm -
2 stops18h 07m
Tue 10/131:27 pm -
2 stops16h 48m
Deal found 9/25![Delta logo]()
$594
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:10 pm -
2 stops15h 37m
Wed 10/2812:49 pm -
2 stops16h 11m
Deal found 9/25![Delta logo]()
$594
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:25 pm -
2 stops17h 29m
Wed 11/2511:27 am -
2 stops15h 08m
Deal found 9/24![Delta logo]()
$644
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:40 pm -
2 stops18h 07m
Thu 10/229:29 am -
2 stops19h 26m
Deal found 9/22![Delta logo]()
$832
Last-minute flights from Santiago to ChicagoDiscover last-minute flight deals from Santiago to Chicago. Data last updated September 27, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to Chicago. Data last updated September 27, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:30 am -
1 stop21h 50m
Thu 10/2211:20 pm -
1 stop13h 55m
Deal found 9/25![Avianca logo]()
$588
This Flightnetwork deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:20 pm -
1 stop31h 00m
Tue 10/611:20 pm -
1 stop13h 55m
Deal found 9/24![Avianca logo]()
$610
This Avianca deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:40 am -
1 stop15h 40m
Mon 10/1911:20 pm -
1 stop13h 55m
Deal found 9/25![Avianca logo]()
$597
This Copa Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:23 pm -
1 stop14h 34m
Mon 10/193:20 pm -
1 stop31h 02m
Deal found 9/26![Copa Airlines logo]()
$638
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:55 pm -
2 stops19h 03m
Mon 10/196:30 am -
1 stop23h 45m
Deal found 9/23![Delta logo]()
$644
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:40 pm -
1 stop17h 14m
Tue 10/131:27 pm -
2 stops16h 48m
Deal found 9/25![Delta logo]()
$594
This LATAM Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:40 pm -
1 stop15h 23m
Thu 10/226:04 am -
2 stops30h 31m
Deal found 9/25![LATAM Airlines logo]()
$598
This Justfly.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:40 pm -
1 stop15h 23m
Tue 10/135:09 pm -
1 stop13h 06m
Deal found 9/25![LATAM Airlines logo]()
$602
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:55 pm -
2 stops18h 19m
Mon 10/265:09 pm -
1 stop12h 31m
Deal found 9/24![Delta logo]()
$641
This LATAM Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:55 pm -
2 stops16h 59m
Tue 11/36:04 am -
1 stop22h 36m
Deal found 9/26![LATAM Airlines logo]()
$604
This LATAM Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:10 pm -
1 stop14h 44m
Mon 11/26:04 am -
2 stops22h 26m
Deal found 9/26![LATAM Airlines logo]()
$605
This Cheapflightsfares deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:10 pm -
1 stop14h 37m
Sat 11/76:04 am -
2 stops22h 26m
Deal found 9/25![LATAM Airlines logo]()
$642
One-way flights from Santiago to ChicagoSearch for one-way flight options from Santiago to Chicago. Find affordable one-way fares based on user searches. Data last updated September 27, 2026.
Search for one-way flight options from Santiago to Chicago. Find affordable one-way fares based on user searches. Data last updated September 27, 2026.
This Avianca deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/47:30 am -
1 stop16h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Avianca logo]()
$361
This Justfly.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:15 pm -
1 stop31h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Avianca logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/410:12 pm -
2 stops27h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$384
This Mytrip deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:15 pm -
1 stop31h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Avianca logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2410:00 am -
1 stop15h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Arajet logo]()
$396
This Air Canada deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/309:55 pm -
1 stop14h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Air Canada logo]()
$400
This Kissandfly.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/242:10 am -
1 stop21h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Avianca logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/139:25 am -
3 stops40h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$516
This Mytrip deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:30 am -
3 stops24h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Multiple Airlines logo]()
$524
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/44:15 pm -
3 stops34h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$528
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2512:20 pm -
3 stops30h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$574
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/238:35 pm -
3 stops29h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Multiple Airlines logo]()
$583
Find flight deals from Santiago to Chicago
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $559 (FlightHub) |
One-way from | $375 (Justfly.com) |
Popular in | January |
Cheapest in | April |
Average price | $794 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 27, 2026.
Use the filters below to find and compare flights from Santiago to Chicago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
SantiagoChicago
SCL Santiago Arturo Merino Benitez - ORD Chicago O'Hare Intl
SCLORD
Santiago Arturo Merino Benitez
Sat 3/13
7:30 am-8:30 pm
1 stop16h 00m
Chicago O'Hare Intl
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$363
SantiagoChicago
SCL Santiago Arturo Merino Benitez - ORD Chicago O'Hare Intl
SCLORD
Santiago Arturo Merino Benitez
Thu 2/4
7:30 am-8:30 pm
1 stop16h 00m
Chicago O'Hare Intl
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$363
SantiagoChicago
SCL Santiago Arturo Merino Benitez - ORD Chicago O'Hare Intl
SCLORD
Santiago Arturo Merino Benitez
Tue 12/1
4:15 pm-8:30 pm
1 stop31h 15m
Chicago O'Hare Intl
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$375
SantiagoChicago
SCL Santiago Arturo Merino Benitez - ORD Chicago O'Hare Intl
SCLORD
Santiago Arturo Merino Benitez
Thu 2/4
10:12 pm-10:13 pm
2 stops27h 01m
Chicago O'Hare Intl
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$384
SantiagoChicago
SCL Santiago Arturo Merino Benitez - ORD Chicago O'Hare Intl
SCLORD
Santiago Arturo Merino Benitez
Sat 12/5
4:15 pm-8:30 pm
1 stop31h 15m
Chicago O'Hare Intl
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$391
SantiagoChicago
SCL Santiago Arturo Merino Benitez - ORD Chicago O'Hare Intl
SCLORD
Santiago Arturo Merino Benitez
Tue 12/1
9:55 pm-2:52 pm
2 stops19h 57m
Chicago O'Hare Intl
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$404
SantiagoChicago
SCL Santiago Arturo Merino Benitez - ORD Chicago O'Hare Intl
SCLORD
Santiago Arturo Merino Benitez
Tue 3/23
8:35 pm-11:06 pm
2 stops28h 31m
Chicago O'Hare Intl
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$404
SantiagoChicago
SCL Santiago Arturo Merino Benitez - ORD Chicago O'Hare Intl
SCLORD
Santiago Arturo Merino Benitez
Mon 11/30
9:55 pm-3:38 pm
1 stop20h 43m
Chicago O'Hare Intl
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$410
SantiagoChicago
SCL Santiago Arturo Merino Benitez - ORD Chicago O'Hare Intl
SCLORD
Santiago Arturo Merino Benitez
Fri 12/25
6:52 pm-10:13 pm
3 stops54h 21m
Chicago O'Hare Intl
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$460
SantiagoChicago
SCL Santiago Arturo Merino Benitez - MDW Chicago Midway
SCLMDW
Santiago Arturo Merino Benitez
Sat 3/13
9:25 am-10:46 pm
3 stops40h 21m
Chicago Midway
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$516
Showing 1-10 of 31 resultsSorted by cheapest first
Compare providers for flights from Santiago to Chicago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Chicago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santiago-Chicago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Chicago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Chicago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-Chicago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Santiago with our price prediction graph.
SCL-CHI
SCL-ORD
SCL-MDW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Chicago
SCL-CHI
SCL-ORD
SCL-MDW
What is the cheapest month to book a flight from Santiago to Chicago?
Currently, April is the cheapest month in which you can book a flight from Santiago to Chicago (average of $648). Flying from Santiago to Chicago in January is currently the most expensive (average of $1,024). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to Chicago?
Airfare is below average for this route at the moment.
Santiago to Chicago flights typically cost between $606 and $776 in October.The cheapest round-trip price found within the last 5 days was $559 on LATAM Airlines (Oct 28-Nov 4).
How far ahead should I book a flight from Santiago to Chicago?
To ensure you get the cheapest price possible for a flight from Santiago to Chicago, you should look to book at least 44 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated September 27, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Santiago to Chicago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Comfort
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Food
7.2
Comfort
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Food
7.2
Comfort
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Food
7.2
Comfort
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Food
7.2
Comfort
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Santiago to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsBenton Harbor
Lansing
Merrillville
Valparaiso
Hammond
Saint Joseph
Porter
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Santiago to Chicago
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Chicago
Explore flights to Chicago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 27, 2026.
Complete your trip
Complete your trip to Chicago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Santiago to Chicago by cabin class
Find flights from Santiago to Chicago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Santiago and Chicago flights
Browse other Santiago and Chicago flight options. Last updated on September 27, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on September 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Santiago to Chicago
Discover the top 5 airlines that operate flights from Santiago to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$316 | Average$625 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$343 | Average$814 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$573 | Average$700 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$587 | Average$817 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$596 | Average$654 | FlexibilityNo cancel fee | On-timeN/A |