$314+ Cheap flights from Santiago (SCL) to Chicago (CHI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/14. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — CHI
Jun 17 — Jun 241
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Santiago to Chicago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santiago to Chicago
Cheapest
Best
Last-minute
One-way
Cheapest flights from Santiago to ChicagoExplore the most affordable flight options available from Santiago to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
Explore the most affordable flight options available from Santiago to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
This LATAM Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:05 pm
SCL
- ORD
1 stop19h 44m
LATAM Airlines
Thu 6/181:46 pm
ORD
- SCL
2 stops16h 04m
LATAM Airlines
Deal found 5/18![LATAM Airlines logo]()
$606
This eDestinos deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:55 pm
SCL
- ORD
1 stop20h 39m
LATAM Airlines
Tue 11/311:10 am
ORD
- SCL
2 stops15h 25m
LATAM Airlines
Deal found 5/17![LATAM Airlines logo]()
$607
This ViajaNet deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ViajaNet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:00 pm
SCL
- ORD
2 stops17h 19m
LATAM Airlines
Tue 9/291:15 pm
ORD
- SCL
2 stops15h 40m
LATAM Airlines
Deal found 5/18![LATAM Airlines logo]()
$610
This eDestinos deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1511:05 pm
SCL
- ORD
1 stop19h 06m
LATAM Airlines
Wed 7/811:20 am
ORD
- SCL
1 stop18h 55m
LATAM Airlines
Deal found 5/18![LATAM Airlines logo]()
$616
This eDestinos deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:05 pm
SCL
- ORD
1 stop19h 06m
LATAM Airlines
Wed 6/2411:23 am
ORD
- SCL
2 stops17h 12m
LATAM Airlines
Deal found 5/15![LATAM Airlines logo]()
$618
This LATAM Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:00 pm
SCL
- ORD
2 stops20h 46m
LATAM Airlines
Thu 11/121:15 pm
ORD
- SCL
1 stop15h 25m
LATAM Airlines
Deal found 5/18![LATAM Airlines logo]()
$620
This LATAM Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:05 pm
SCL
- ORD
1 stop19h 44m
LATAM Airlines
Wed 6/101:46 pm
ORD
- SCL
1 stop16h 29m
LATAM Airlines
Deal found 5/16![LATAM Airlines logo]()
$621
This eDestinos deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:55 pm
SCL
- ORD
1 stop19h 11m
LATAM Airlines
Mon 8/2410:07 am
ORD
- SCL
2 stops19h 48m
LATAM Airlines
Deal found 5/16![LATAM Airlines logo]()
$622
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/2610:55 pm
SCL
- ORD
1 stop19h 11m
Multiple Airlines
Sat 8/812:44 am
ORD
- SCL
2 stops26h 11m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$624
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:40 pm
SCL
- MDW
1 stop14h 29m
Delta
Wed 7/19:17 am
MDW
- SCL
2 stops20h 58m
Delta
Deal found 5/16![Delta logo]()
$633
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:40 pm
SCL
- MDW
1 stop14h 19m
Delta
Sun 8/1610:54 am
MDW
- SCL
2 stops19h 01m
Delta
Deal found 5/17![Delta logo]()
$634
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:40 pm
SCL
- MDW
2 stops16h 58m
Delta
Wed 9/25:25 pm
MDW
- SCL
1 stop12h 50m
Delta
Deal found 5/16![Delta logo]()
$639
Best flights from Santiago to ChicagoDiscover carefully curated flight deals from Santiago to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
Discover carefully curated flight deals from Santiago to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:05 pm
SCL
- ORD
1 stop19h 06m
Delta
Sun 7/56:35 am
ORD
- SCL
1 stop23h 40m
Delta
Deal found 5/18![Delta logo]()
$634
This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:56 am
SCL
- ORD
1 stop26h 04m
Copa Airlines
Wed 8/198:02 am
ORD
- SCL
1 stop13h 41m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$643
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:00 pm
SCL
- MDW
2 stops20h 33m
Delta
Sun 8/235:10 pm
MDW
- SCL
1 stop13h 05m
Delta
Deal found 5/18![Delta logo]()
$634
This Copa Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:15 am
SCL
- ORD
1 stop21h 42m
Copa Airlines
Mon 10/193:20 pm
ORD
- SCL
1 stop30h 19m
Copa Airlines
Deal found 5/14![Copa Airlines logo]()
$643
This Copa Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:56 am
SCL
- ORD
1 stop22h 05m
Copa Airlines
Fri 8/213:21 pm
ORD
- SCL
1 stop30h 22m
Copa Airlines
Deal found 5/15![Copa Airlines logo]()
$643
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:00 pm
SCL
- ORD
2 stops19h 04m
Delta
Wed 6/241:46 pm
ORD
- SCL
2 stops14h 49m
Delta
Deal found 5/14![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:40 pm
SCL
- ORD
1 stop21h 32m
Delta
Fri 8/211:48 pm
ORD
- SCL
2 stops16h 07m
Delta
Deal found 5/18![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1610:55 pm
SCL
- ORD
1 stop23h 53m
Delta
Sun 6/285:30 am
ORD
- SCL
1 stop24h 45m
Delta
Deal found 5/16![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:40 pm
SCL
- ORD
1 stop17h 26m
Delta
Tue 10/201:15 pm
ORD
- SCL
2 stops15h 40m
Delta
Deal found 5/15![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:40 pm
SCL
- ORD
1 stop17h 26m
Delta
Sun 10/1111:10 am
ORD
- SCL
2 stops17h 45m
Delta
Deal found 5/17![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:40 pm
SCL
- MDW
1 stop14h 19m
Delta
Wed 8/191:27 pm
MDW
- SCL
2 stops16h 48m
Delta
Deal found 5/13![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:40 pm
SCL
- MDW
1 stop20h 35m
Delta
Wed 8/1910:54 am
MDW
- SCL
1 stop19h 21m
Delta
Deal found 5/17![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:40 pm
SCL
- MDW
1 stop15h 12m
Delta
Sat 10/2410:35 am
MDW
- SCL
1 stop19h 05m
Delta
Deal found 5/14![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/711:05 pm
SCL
- MDW
2 stops20h 26m
Delta
Sun 8/3012:46 pm
MDW
- SCL
2 stops15h 49m
Delta
Deal found 5/17![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:05 pm
SCL
- MDW
2 stops19h 51m
Delta
Wed 6/1012:50 pm
MDW
- SCL
2 stops15h 45m
Delta
Deal found 5/16![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:40 pm
SCL
- MDW
2 stops16h 58m
Delta
Fri 8/2112:46 pm
MDW
- SCL
2 stops17h 09m
Delta
Deal found 5/15![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:00 pm
SCL
- MDW
2 stops19h 25m
Delta
Sun 10/1110:35 am
MDW
- SCL
2 stops18h 20m
Delta
Deal found 5/17![Delta logo]()
$646
Last-minute flights from Santiago to ChicagoDiscover last-minute flight deals from Santiago to Chicago. Data last updated May 18, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to Chicago. Data last updated May 18, 2026 and is based on user searches.
This LATAM Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:00 pm
SCL
- ORD
2 stops18h 56m
LATAM Airlines
Wed 12/210:40 am
ORD
- SCL
2 stops15h 55m
LATAM Airlines
Deal found 5/17![LATAM Airlines logo]()
$620
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:40 pm
SCL
- MDW
1 stop14h 20m
Delta
Tue 6/239:17 am
MDW
- SCL
2 stops20h 58m
Delta
Deal found 5/14![Delta logo]()
$646
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:40 pm
SCL
- ORD
1 stop21h 16m
Delta
Sun 6/211:00 pm
ORD
- SCL
1 stop16h 25m
Delta
Deal found 5/16![Delta logo]()
$633
This LATAM Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:05 pm
SCL
- MDW
2 stops23h 04m
LATAM Airlines
Tue 6/165:11 pm
MDW
- SCL
1 stop13h 04m
LATAM Airlines
Deal found 5/17![LATAM Airlines logo]()
$642
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:05 pm
SCL
- ORD
1 stop19h 44m
Multiple Airlines
Wed 6/174:59 pm
ORD
- SCL
2 stops33h 01m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$635
This LATAM Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:05 pm
SCL
- ORD
1 stop19h 44m
LATAM Airlines
Thu 6/181:46 pm
ORD
- SCL
2 stops16h 04m
LATAM Airlines
Deal found 5/18![LATAM Airlines logo]()
$606
This LATAM Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:05 pm
SCL
- ORD
1 stop19h 44m
LATAM Airlines
Wed 6/101:46 pm
ORD
- SCL
1 stop16h 29m
LATAM Airlines
Deal found 5/16![LATAM Airlines logo]()
$621
This eDestinos deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:05 pm
SCL
- ORD
1 stop19h 06m
LATAM Airlines
Wed 6/2411:23 am
ORD
- SCL
2 stops17h 12m
LATAM Airlines
Deal found 5/15![LATAM Airlines logo]()
$618
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:40 pm
SCL
- MDW
1 stop14h 29m
Delta
Wed 7/19:17 am
MDW
- SCL
2 stops20h 58m
Delta
Deal found 5/16![Delta logo]()
$633
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:05 pm
SCL
- ORD
2 stops18h 21m
Delta
Mon 7/61:40 pm
ORD
- SCL
2 stops16h 35m
Delta
Deal found 5/18![Delta logo]()
$634
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:40 pm
SCL
- MDW
1 stop14h 29m
Delta
Sat 7/44:25 pm
MDW
- SCL
1 stop13h 50m
Delta
Deal found 5/18![Delta logo]()
$634
This eDestinos deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1511:05 pm
SCL
- ORD
1 stop19h 06m
LATAM Airlines
Wed 7/811:20 am
ORD
- SCL
1 stop18h 55m
LATAM Airlines
Deal found 5/18![LATAM Airlines logo]()
$616
One-way flights from Santiago to ChicagoSearch for one-way flight options from Santiago to Chicago. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
Search for one-way flight options from Santiago to Chicago. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
This eDestinos deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/1411:05 pm
SCL
- ORD
1 stop19h 06m
LATAM Airlines
Deal found 5/18![LATAM Airlines logo]()
$314
This eDestinos deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/210:30 am
SCL
- ORD
2 stops24h 43m
LATAM Airlines
Deal found 5/18![LATAM Airlines logo]()
$318
This FlightHub deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:05 pm
SCL
- ORD
1 stop19h 49m
LATAM Airlines
Deal found 5/17![LATAM Airlines logo]()
$320
This LATAM Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/710:30 am
SCL
- ORD
2 stops24h 43m
LATAM Airlines
Deal found 5/15![LATAM Airlines logo]()
$325
This eDestinos deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:30 am
SCL
- ORD
2 stops24h 46m
LATAM Airlines
Deal found 5/15![LATAM Airlines logo]()
$328
This eDestinos deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:40 am
SCL
- ORD
2 stops19h 05m
LATAM Airlines
Deal found 5/17![LATAM Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:40 pm
SCL
- ORD
1 stop23h 05m
Delta
Deal found 5/17![Delta logo]()
$336
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:40 pm
SCL
- MDW
2 stops22h 45m
Delta
Deal found 5/17![Delta logo]()
$336
This Copa Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/24:09 am
SCL
- ORD
1 stop24h 51m
Copa Airlines
Deal found 5/15![Copa Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:25 pm
SCL
- ORD
1 stop20h 56m
Delta
Deal found 5/16![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:10 pm
SCL
- MDW
2 stops16h 23m
Delta
Deal found 5/16![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:40 pm
SCL
- MDW
1 stop14h 20m
Delta
Deal found 5/15![Delta logo]()
$343
Find flight deals from Santiago to Chicago
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $606 (LATAM Airlines) |
One-way from | $314 (eDestinos) |
Popular in | January |
Cheapest in | March |
Average price | $808 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Santiago to Chicago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Tue 6/16
11:05 pm-5:11 pm
1 stop19h 06m
Chicago O'Hare Intl
Sun 7/5
6:35 am-7:15 am
1 stop23h 40m
$634
SantiagoChicago
SCL - MDW
SCLMDW
Santiago Arturo Merino Benitez
Wed 8/12
11:00 pm-6:33 pm
2 stops20h 33m
Chicago Midway
Sun 8/23
5:10 pm-7:15 am
1 stop13h 05m
$634
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Wed 7/29
2:56 am-4:00 am
1 stop26h 04m
Chicago O'Hare Intl
Wed 8/19
8:02 am-10:43 pm
1 stop13h 41m
$643
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Mon 10/12
5:15 am-12:57 am
1 stop21h 42m
Chicago O'Hare Intl
Mon 10/19
3:20 pm-11:39 pm
1 stop30h 19m
$643
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Thu 7/30
2:56 am-12:01 am
1 stop22h 05m
Chicago O'Hare Intl
Fri 8/21
3:21 pm-10:43 pm
1 stop30h 22m
$643
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Wed 6/10
11:00 pm-5:04 pm
2 stops19h 04m
Chicago O'Hare Intl
Wed 6/24
1:46 pm-5:35 am
2 stops14h 49m
$646
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Fri 7/31
8:40 pm-5:12 pm
1 stop21h 32m
Chicago O'Hare Intl
Fri 8/21
1:48 pm-6:55 am
2 stops16h 07m
$646
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Tue 6/16
10:55 pm-9:48 pm
1 stop23h 53m
Chicago O'Hare Intl
Sun 6/28
5:30 am-7:15 am
1 stop24h 45m
$646
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Fri 10/16
8:40 pm-12:06 pm
1 stop17h 26m
Chicago O'Hare Intl
Tue 10/20
1:15 pm-6:55 am
2 stops15h 40m
$646
SantiagoChicago
SCL - ORD
SCLORD
Santiago Arturo Merino Benitez
Mon 10/5
8:40 pm-12:06 pm
1 stop17h 26m
Chicago O'Hare Intl
Sun 10/11
11:10 am-6:55 am
2 stops17h 45m
$646
Showing 1-10 of 37 resultsSorted by cheapest first
Compare providers for flights from Santiago to Chicago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Chicago in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santiago-Chicago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Chicago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Chicago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-Chicago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Santiago with our price prediction graph.
SCL-CHI
SCL-ORD
SCL-MDW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Chicago
SCL-CHI
SCL-ORD
SCL-MDW
How far ahead should I book a flight from Santiago to Chicago?
To ensure you get the cheapest price possible for a flight from Santiago to Chicago, you should look to book at least 88 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Santiago to Chicago?
Currently, April is the cheapest month in which you can book a flight from Santiago to Chicago (average of $253). Flying from Santiago to Chicago in August is currently the most expensive (average of $605). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to Chicago?
How often are flights from Santiago to Chicago delayed?
About 0% of weekly flights between Santiago and Chicago have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for Santiago to Chicago flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Monday tends to have the lowest number of delays on this route, whereas Tuesday has historically faced a higher average of delays compared to other days of the week.
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated May 18, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Santiago to Chicago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.9
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentRakshith,May 2026
TPE - SEA
Entertainment
7.8
Overall
7.9
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentRakshith,May 2026
TPE - SEA
Entertainment
7.8
Overall
7.9
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentRakshith,May 2026
TPE - SEA
Entertainment
7.8
Overall
7.9
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentRakshith,May 2026
TPE - SEA
Related info for your journey
Find useful and relevant information for your journey from Santiago to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsBenton Harbor
Lansing
Merrillville
Hammond
Porter
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Chicago flight routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Santiago
Popular flights
Alternative routes for Santiago to Chicago
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Chicago
Explore flights to Chicago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 18, 2026.
Complete your trip
Complete your trip to Chicago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Santiago to Chicago by cabin class
Find flights from Santiago to Chicago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Santiago and Chicago flights
Browse other Santiago and Chicago flight options. Last updated on May 18, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on May 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Santiago to Chicago
Discover the top 4 airlines that operate flights from Santiago to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$347 | Average$684 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$583 | Average$809 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$587 | Average$893 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$588 | Average$673 | FlexibilityNo cancel fee | On-time81% |