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$157+ Cheap flights from Knoxville to Charleston (TYS - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CHS
dic. 24 — dic. 311
mié. 12/24
mié. 12/31
1 adult, Economy
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Find flight deals from Knoxville to Charleston

Cheapest flights from Knoxville to Charleston
Explore the most affordable flight options available from Knoxville to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 24, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/85:34 pmTYS - CHS
1 stop15h 03mMultiple Airlines
vie. 12/129:49 pmCHS - TYS
1 stop14h 14mMultiple Airlines
Deal found 11/22$236
This Kiwi.com deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/78:30 amTYS - CHS
2 stops38h 49mMultiple Airlines
jue. 12/1111:55 amCHS - TYS
1 stop24h 00mMultiple Airlines
Deal found 11/22$290
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/151:05 pmTYS - CHS
1 stop19h 32mMultiple Airlines
mié. 12/178:10 pmCHS - TYS
2 stops17h 56mMultiple Airlines
Deal found 11/24$312
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/239:27 pmTYS - CHS
2 stops35h 10mMultiple Airlines
mar. 12/302:15 pmCHS - TYS
1 stop22h 43mMultiple Airlines
Deal found 11/23$347
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/85:39 pmTYS - CHS
1 stop6h 11mDelta
sáb. 12/133:30 pmCHS - TYS
1 stop4h 40mDelta
Deal found 11/23$377
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/96:00 pmTYS - CHS
1 stop3h 48mDelta
sáb. 12/137:00 amCHS - TYS
1 stop5h 24mDelta
Deal found 11/23$407

Cheap flight deals from Knoxville to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated noviembre 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$236
(Kiwi.com)

One-way from

$157
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$485
Provider with most accurate pricing for Knoxville McGhee Tyson-Charleston flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Charleston flights.
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From Knoxville McGhee Tyson to Charleston
Search Deals
One-way flight from Knoxville McGhee Tyson to Charleston
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($127 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 24, 2025.
Use the filters below to find and compare flights from Knoxville to Charleston that are best for you.

Fly from

Knoxville

Fly to

Charleston

Route

Depart

Return

Price

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

vie. 1/23

7:15 am-4:10 pm

1 stop8h 55m

Charleston

sáb. 1/24

6:31 pm-8:39 am

1 stop14h 08m

$211

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

lun. 12/8

5:34 pm-8:37 am

1 stop15h 03m

Charleston

vie. 12/12

9:49 pm-12:03 pm

1 stop14h 14m

$236

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

lun. 12/15

1:05 pm-8:37 am

1 stop19h 32m

Charleston

mié. 12/17

8:10 pm-2:06 pm

2 stops17h 56m

$312

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

jue. 1/8

11:05 am-4:06 pm

1 stop5h 01m

Charleston

lun. 1/12

10:25 am-3:19 pm

1 stop4h 54m

$327

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

vie. 1/9

5:40 am-9:19 am

1 stop3h 39m

Charleston

lun. 1/12

12:53 pm-5:16 pm

1 stop4h 23m

$327

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

vie. 1/16

4:00 pm-9:11 pm

1 stop5h 11m

Charleston

dom. 1/18

6:10 am-11:47 am

1 stop5h 37m

$347

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

vie. 1/16

5:36 pm-11:58 pm

1 stop6h 22m

Charleston

lun. 1/19

7:42 pm-10:54 pm

1 stop3h 12m

$347

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

mar. 12/23

9:27 pm-8:37 am

2 stops35h 10m

Charleston

mar. 12/30

2:15 pm-12:58 pm

1 stop22h 43m

$347

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

mar. 12/23

9:27 pm-8:37 am

2 stops35h 10m

$157

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

dom. 11/30

11:29 am-8:37 am

2 stops45h 08m

$172

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Showing 1-10 of 13 results
1
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Compare providers for flights from Knoxville to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Charleston in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Charleston

What is the cheapest month to book a flight from Knoxville to Charleston?

Currently, June is the cheapest month in which you can book a flight from Knoxville to Charleston (average of $174). Flying from Knoxville to Charleston in March is currently the most expensive (average of $267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to CHS?

Find hourly flight availability from Knoxville to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 24, 2025.

When flying from Knoxville to Charleston, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 18% versus a flight in the afternoon.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated noviembre 24, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Knoxville to Charleston to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,997 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
7,997 reviews
Delta
7.9
Good
7,997 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,046 reviews
Delta
7.9
Good
7,997 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Charleston round-trip?

    Currently priced at $296, American Airlines will fly you from Knoxville to Charleston and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $316. You may be able to fly from Knoxville to Charleston for 35% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Charleston that include hotel bookings?

    Yes. In addition to deals on Knoxville to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Charleston.

  • Can I find deals for business class flights from Knoxville to Charleston?

    Yes. Cheapflights offers flight deals from Knoxville to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Charleston?

    Currently, June is the cheapest month in which you can book a flight from Knoxville to Charleston (average of $174). Flying from Knoxville to Charleston in March is currently the most expensive (average of $267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Santee
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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Top 2 airlines flying from Knoxville to Charleston

Discover the top 2 airlines that operate flights from Knoxville to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$296Average$417FlexibilityNo cancel feeOn-time71%
DeltaCheapest$316Average$458FlexibilityNo cancel feeOn-timeN/A

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