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$114+ Cheap flights from Knoxville to Charleston (TYS - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CHS
Apr 17 — Apr 241
Fri 4/17
Fri 4/24
1 adult, Economy
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Cheap flight deals from Knoxville to Charleston

Cheapest flights from Knoxville to Charleston
Explore the most affordable flight options available from Knoxville to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 18, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:03 pm
TYS
-
CHS
1 stop14h 42m
Multiple Airlines
Mon 6/13:23 pm
CHS
-
TYS
1 stop24h 47m
Multiple Airlines
Deal found 3/15$249
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:04 pm
TYS
-
CHS
1 stop20h 00m
Multiple Airlines
Sat 8/223:44 pm
CHS
-
TYS
1 stop20h 21m
Multiple Airlines
Deal found 3/17$287
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/131:15 pm
TYS
-
CHS
1 stop19h 23m
Multiple Airlines
Mon 4/208:28 pm
CHS
-
TYS
2 stops38h 08m
Multiple Airlines
Deal found 3/16$291
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:15 pm
TYS
-
CHS
1 stop20h 18m
Multiple Airlines
Sat 5/96:18 pm
CHS
-
TYS
2 stops42h 58m
Multiple Airlines
Deal found 3/15$298
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:45 am
TYS
-
CHS
1 stop6h 20m
Southwest
Tue 4/286:40 am
CHS
-
TYS
1 stop5h 20m
Southwest
Deal found 3/16$299
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/289:36 pm
TYS
-
CHS
1 stop24h 37m
Multiple Airlines
Wed 4/15:16 pm
CHS
-
TYS
2 stops30h 23m
Multiple Airlines
Deal found 3/13$300
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/49:26 am
TYS
-
CHS
1 stop12h 47m
Multiple Airlines
Wed 4/85:16 pm
CHS
-
TYS
2 stops44h 00m
Multiple Airlines
Deal found 3/14$301
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:30 am
TYS
-
CHS
1 stop24h 08m
Multiple Airlines
Sun 4/53:01 pm
CHS
-
TYS
1 stop27h 20m
Multiple Airlines
Deal found 3/17$304
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:14 pm
TYS
-
CHS
1 stop8h 45m
Multiple Airlines
Sun 4/268:59 pm
CHS
-
TYS
1 stop24h 49m
Multiple Airlines
Deal found 3/16$305
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:30 am
TYS
-
CHS
1 stop24h 08m
Multiple Airlines
Mon 4/68:28 pm
CHS
-
TYS
2 stops17h 38m
Multiple Airlines
Deal found 3/16$306
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:00 am
TYS
-
CHS
1 stop4h 52m
American Airlines
Thu 4/238:21 pm
CHS
-
TYS
1 stop3h 34m
American Airlines
Deal found 3/17$308

Find flight deals from Knoxville to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$249
(Kiwi.com)

One-way from

$114
(Kiwi.com)

Popular in

January

Cheapest in

August

Average price

$473
Provider with most accurate pricing for Knoxville McGhee Tyson-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Charleston flights.
Search Deals
From Knoxville McGhee Tyson to Charleston
Search Deals
One-way flight from Knoxville McGhee Tyson to Charleston
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($88 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Knoxville to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Tue 4/14

8:15 am-5:40 pm

2 stops9h 25m

Charleston

Tue 4/21

6:40 am-12:00 pm

1 stop5h 20m

$304

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Wed 6/10

8:10 am-8:25 pm

2 stops12h 15m

Charleston

Sat 6/13

6:30 am-11:55 am

1 stop5h 25m

$323

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Thu 5/28

8:05 am-6:20 pm

2 stops10h 15m

Charleston

Mon 6/1

1:15 pm-9:15 pm

2 stops8h 00m

$328

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Mon 6/15

12:35 pm-9:55 pm

2 stops9h 20m

Charleston

Thu 6/18

4:10 pm-10:20 pm

1 stop6h 10m

$342

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Sat 6/6

8:00 am-3:25 pm

1 stop7h 25m

Charleston

Sat 6/13

6:30 am-11:55 am

1 stop5h 25m

$342

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Thu 5/28

8:05 am-6:20 pm

2 stops10h 15m

Charleston

Sun 5/31

6:15 am-11:40 am

1 stop5h 25m

$343
Quickest round-trip

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Fri 5/8

7:33 pm-11:59 pm

1 stop4h 26m

Charleston

Wed 5/13

5:15 am-9:34 am

1 stop4h 19m

$357

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Fri 5/8

12:15 pm-9:30 pm

2 stops9h 15m

Charleston

Sun 5/10

6:15 am-11:40 am

1 stop5h 25m

$362

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Thu 5/7

8:05 am-6:20 pm

2 stops10h 15m

Charleston

Sun 5/10

7:40 am-9:05 pm

2 stops13h 25m

$383
Cheapest one-way

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Sat 5/2

1:15 pm-7:29 pm

1 stop6h 14m

$150

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/13

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Charleston in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Charleston

What is the cheapest month to book a flight from Knoxville to Charleston?

Currently, June is the cheapest month in which you can book a flight from Knoxville to Charleston (average of $168). Flying from Knoxville to Charleston in December is currently the most expensive (average of $275). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated March 18, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Knoxville to Charleston to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,286 reviews

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,286 reviews
Delta
7.9
Good
8,286 reviews

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,468 reviews
Delta
7.9
Good
8,286 reviews

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Charleston?

    A quick flight from Knoxville to Charleston can take about 9h 25m. Southwest provides one of the quickest options available for as low as $304. The distance between Knoxville and Charleston is about 302 mi.

  • What are the cheapest airlines flying from Knoxville to Charleston round-trip?

    Currently priced at $286, American Airlines will fly you from Knoxville to Charleston and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $316. You may be able to fly from Knoxville to Charleston for 33% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Charleston that include hotel bookings?

    Yes. In addition to deals on Knoxville to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Charleston.

  • Can I find deals for business class flights from Knoxville to Charleston?

    Yes. Cheapflights offers flight deals from Knoxville to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Charleston?

    Currently, June is the cheapest month in which you can book a flight from Knoxville to Charleston (average of $168). Flying from Knoxville to Charleston in December is currently the most expensive (average of $275). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Walterboro
Summerville
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Knoxville to Charleston

Discover the top 2 airlines that operate flights from Knoxville to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$286Average$426FlexibilityNo cancel feeOn-time71%
DeltaCheapest$316Average$398FlexibilityNo cancel feeOn-timeN/A

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