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Central America

$134+ Cheap flights from Greenville (GSP) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SJO
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Greenville to Central America

Cheapest flights from Greenville to Central America
Explore the most affordable flight options available from Greenville to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:43 pm
GSP
-
GUA
1 stop8h 16m
Multiple Airlines
Sun 4/2612:29 pm
GUA
-
GSP
1 stop26h 24m
Multiple Airlines
Deal found 1/26$325
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:43 pm
GSP
-
SJO
1 stop18h 39m
Multiple Airlines
Sun 3/1512:24 pm
SJO
-
GSP
1 stop26h 51m
Multiple Airlines
Deal found 1/26$355
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:43 pm
GSP
-
GUA
1 stop19h 41m
Multiple Airlines
Mon 5/45:25 am
GUA
-
GSP
2 stops12h 13m
Multiple Airlines
Deal found 1/26$370
This Avianca deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:00 am
GSP
-
SAL
1 stop11h 00m
Multiple Airlines
Tue 7/2112:05 pm
SAL
-
GSP
1 stop7h 41m
Multiple Airlines
Deal found 1/26$370
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:17 pm
GSP
-
SJO
1 stop20h 05m
Multiple Airlines
Sun 3/112:35 pm
SJO
-
GSP
1 stop30h 03m
Multiple Airlines
Deal found 1/25$379
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:33 pm
GSP
-
GUA
1 stop7h 26m
Multiple Airlines
Sat 4/1111:28 am
GUA
-
GSP
1 stop24h 25m
Multiple Airlines
Deal found 1/27$385
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/84:41 pm
GSP
-
SJO
1 stop20h 41m
Multiple Airlines
Sun 3/1512:24 pm
SJO
-
GSP
1 stop26h 51m
Multiple Airlines
Deal found 1/26$392
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/68:18 pm
GSP
-
GUA
1 stop16h 02m
Multiple Airlines
Sat 2/141:28 pm
GUA
-
GSP
1 stop25h 59m
Multiple Airlines
Deal found 1/26$399
This Avianca deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:10 pm
GSP
-
GUA
1 stop7h 50m
Multiple Airlines
Mon 8/178:20 am
GUA
-
GSP
1 stop10h 51m
Multiple Airlines
Deal found 1/26$411
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:53 pm
GSP
-
PTY
2 stops18h 47m
American Airlines
Wed 3/181:40 pm
PTY
-
GSP
2 stops19h 35m
American Airlines
Deal found 1/24$417
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:43 pm
GSP
-
SJO
1 stop19h 39m
Multiple Airlines
Wed 5/135:05 am
SJO
-
GSP
2 stops25h 38m
Multiple Airlines
Deal found 1/25$417
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:45 pm
GSP
-
SAL
1 stop17h 44m
United Airlines
Tue 7/216:00 am
SAL
-
GSP
1 stop13h 46m
United Airlines
Deal found 1/27$419

Find flight deals from Greenville to Central America

Keep the following information in mind while searching for Greenville to Central America flight deals. Data was last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$325
(Kiwi.com)

One-way from

$134
(Kiwi.com)

Popular in

November

Cheapest in

August

Average price

$547
Provider with most accurate pricing for Greenville-San Salvador El Salvador Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-San Salvador El Salvador Intl flights.
Search Deals
From Greenville to Central America
Search Deals
One-way flight from Greenville to Central America
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($81 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Greenville to Central America that are best for you.

Fly from

Greenville

Fly to

Central America

Route

Depart

Return

Price

GreenvilleGuatemala City

GSP - GUA

GSPGUA

Greenville

Mon 4/13

5:43 pm-11:59 pm

1 stop8h 16m

Guatemala City La Aurora

Sun 4/26

12:29 pm-4:53 pm

1 stop26h 24m

$325

GreenvilleSan José

GSP - SJO

GSPSJO

Greenville

Mon 3/9

6:43 pm-11:22 am

1 stop18h 39m

San José Juan Santamaria Intl

Sun 3/15

12:24 pm-5:15 pm

1 stop26h 51m

$355

GreenvilleGuatemala City

GSP - GUA

GSPGUA

Greenville

Mon 4/20

5:43 pm-11:24 am

1 stop19h 41m

Guatemala City La Aurora

Mon 5/4

5:25 am-7:38 pm

2 stops12h 13m

$370

GreenvilleSan Salvador

GSP - SAL

GSPSAL

Greenville

Tue 6/9

7:00 am-4:00 pm

1 stop11h 00m

San Salvador El Salvador Intl

Tue 7/21

12:05 pm-9:46 pm

1 stop7h 41m

$370

GreenvilleGuatemala City

GSP - GUA

GSPGUA

Greenville

Mon 4/6

6:33 pm-11:59 pm

1 stop7h 26m

Guatemala City La Aurora

Sat 4/11

11:28 am-1:53 pm

1 stop24h 25m

$385

GreenvilleGuatemala City

GSP - GUA

GSPGUA

Greenville

Fri 2/6

8:18 pm-11:20 am

1 stop16h 02m

Guatemala City La Aurora

Sat 2/14

1:28 pm-4:27 pm

1 stop25h 59m

$399

GreenvilleSan José

GSP - SJO

GSPSJO

Greenville

Sun 2/22

5:17 pm-11:40 am

2 stops19h 23m

San José Juan Santamaria Intl

Sun 3/1

12:35 pm-7:38 pm

1 stop30h 03m

$401

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 3/11

6:53 pm-12:40 pm

2 stops18h 47m

Panama City Tocumen Intl

Wed 3/18

1:40 pm-10:15 am

2 stops19h 35m

$417

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 3/11

7:37 pm-2:20 pm

2 stops19h 43m

Panama City Tocumen Intl

Wed 3/25

1:40 pm-10:15 am

2 stops19h 35m

$417

GreenvilleSan Salvador

GSP - SAL

GSPSAL

Greenville

Tue 6/2

7:45 pm-11:29 am

1 stop17h 44m

San Salvador El Salvador Intl

Tue 7/21

6:00 am-9:46 pm

1 stop13h 46m

$419

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 48 results
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Best time to book a flight from Greenville to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Central America

What is the cheapest month to book a flight from Greenville to Central America?

Currently, April is the cheapest month in which you can book a flight from Greenville to Central America (average of $93). Flying from Greenville to Central America in January is currently the most expensive (average of $263). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated January 27, 2026.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Greenville to Central America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,119 reviews

Food

7.2

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,119 reviews
Delta
7.9
Good
8,119 reviews

Food

7.2

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,205 reviews
Delta
7.9
Good
8,119 reviews

Food

7.2

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,197 reviews
Delta
7.9
Good
8,119 reviews

Food

7.2

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Central America?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly out of when you book flights from Greenville to Central America.

  • How long is the flight from Greenville to Central America?

    For as low as $419, American Airlines can have you in Central America from Greenville in 17h 44m. The distance from Greenville to Central America is about 1541 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Greenville to Central America one-way?

    The cheapest airlines for a one-way flight from Greenville to Central America are American Airlines ($158), Delta ($163), and United Airlines ($216).

  • What are the most popular routes from Greenville to Central America?

    The most popular route from Greenville to Central America is Greenville - Panama City Tocumen Intl. You may also consider Greenville - San José Juan Santamaria Intl or Greenville - Liberia.

  • Can I find deals for flights from Greenville to Central America that include hotel bookings?

    Yes. In addition to deals on Greenville to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Central America.

  • Can I find deals for business class flights from Greenville to Central America?

    Yes. Cheapflights offers flight deals from Greenville to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Central America?

    Currently, April is the cheapest month in which you can book a flight from Greenville to Central America (average of $93). Flying from Greenville to Central America in January is currently the most expensive (average of $263). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Greenville to Central America

Discover the top 3 airlines that operate flights from Greenville to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$578FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$353Average$615FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$383Average$552FlexibilityNo cancel feeOn-time69%

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