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Central America

$189+ Cheap flights from Greenville (GSP) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SJO
nov. 28 — dic. 51
vie. 11/28
vie. 12/5
1 adult, Economy
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Find flight deals from Greenville to Central America

Cheapest flights from Greenville to Central America
Explore the most affordable flight options available from Greenville to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/275:17 pmGSP - SJO
2 stops19h 58mMultiple Airlines
jue. 12/412:39 pmSJO - GSP
1 stop29h 44mMultiple Airlines
Deal found 10/28$385
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/58:03 pmGSP - GUA
1 stop16h 20mMultiple Airlines
jue. 1/812:11 pmGUA - GSP
1 stop26h 48mMultiple Airlines
Deal found 10/28$391
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/105:10 amGSP - PTY
1 stop8h 37mAmerican Airlines
mar. 12/162:50 pmPTY - GSP
1 stop9h 09mAmerican Airlines
Deal found 10/27$392
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/108:03 pmGSP - GUA
1 stop16h 18mMultiple Airlines
mar. 11/182:55 pmGUA - GSP
2 stops23h 31mMultiple Airlines
Deal found 10/27$394
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/105:10 amGSP - PTY
1 stop8h 37mAmerican Airlines
mar. 1/132:27 pmPTY - GSP
2 stops21h 40mAmerican Airlines
Deal found 10/28$396
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/195:00 amGSP - PTY
1 stop8h 49mAmerican Airlines
mié. 11/262:43 pmPTY - GSP
1 stop9h 16mAmerican Airlines
Deal found 10/29$398
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/45:00 amGSP - PTY
1 stop8h 49mAmerican Airlines
mié. 11/52:49 pmPTY - GSP
1 stop9h 10mAmerican Airlines
Deal found 10/29$404
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/126:45 amGSP - PTY
1 stop12h 53mUnited Airlines
mié. 11/264:41 pmPTY - GSP
1 stop22h 58mUnited Airlines
Deal found 10/29$406
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/206:22 pmGSP - SAL
2 stops18h 58mAmerican Airlines
jue. 11/271:20 pmSAL - GSP
1 stop20h 44mAmerican Airlines
Deal found 10/27$411
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/104:56 pmGSP - PTY
1 stop21h 49mUnited Airlines
mié. 11/198:55 amPTY - GSP
1 stop13h 04mUnited Airlines
Deal found 10/28$412
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/104:56 pmGSP - PTY
1 stop26h 42mUnited Airlines
jue. 11/274:41 pmPTY - GSP
1 stop22h 58mUnited Airlines
Deal found 10/28$414
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/104:56 pmGSP - PTY
1 stop26h 42mUnited Airlines
mar. 11/254:41 pmPTY - GSP
1 stop29h 18mUnited Airlines
Deal found 10/29$420

Cheap flight deals from Greenville to Central America

Keep the following information in mind while searching for Greenville to Central America flight deals. Data was last updated octubre 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$340
(Kiwi.com)

One-way from

$189
(Delta)

Popular in

November

Cheapest in

August

Average price

$512
Provider with most accurate pricing for Greenville-San Salvador El Salvador Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-San Salvador El Salvador Intl flights.
Search Deals
From Greenville to Central America
Search Deals
One-way flight from Greenville to Central America
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($71 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
Use the filters below to find and compare flights from Greenville to Central America that are best for you.

Fly from

Greenville

Fly to

Central America

Route

Depart

Return

Price

GreenvilleSan Pedro Sula

GSP - SAP

GSPSAP

Greenville

vie. 1/23

4:39 pm-12:48 am

2 stops33h 09m

San Pedro Sula Ramon Villeda

jue. 1/29

1:53 am-8:58 am

1 stop6h 05m

$340

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

mié. 12/10

5:10 am-1:47 pm

1 stop8h 37m

Panama City Tocumen Intl

mar. 12/16

2:50 pm-11:59 pm

1 stop9h 09m

$392

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

mié. 1/21

7:00 am-1:27 pm

1 stop6h 27m

Panama City Tocumen Intl

mié. 2/4

2:27 pm-11:57 pm

1 stop9h 30m

$392

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

mié. 11/19

5:00 am-1:49 pm

1 stop8h 49m

Panama City Tocumen Intl

mié. 11/26

2:43 pm-11:59 pm

1 stop9h 16m

$398

GreenvilleSan Salvador

GSP - SAL

GSPSAL

Greenville

jue. 2/19

6:01 am-1:49 pm

1 stop8h 48m

San Salvador El Salvador Intl

mar. 2/24

1:39 pm-10:42 am

2 stops20h 03m

$402

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

mié. 11/12

6:45 am-7:38 pm

1 stop12h 53m

Panama City Tocumen Intl

mar. 11/25

4:41 pm-3:39 pm

1 stop22h 58m

$406

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

mié. 11/12

6:45 am-2:45 pm

1 stop8h 00m

Panama City Tocumen Intl

jue. 11/27

4:41 pm-3:39 pm

1 stop22h 58m

$406

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

mié. 11/12

6:45 am-7:38 pm

1 stop12h 53m

Panama City Tocumen Intl

mié. 11/26

4:41 pm-3:39 pm

1 stop22h 58m

$406

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

jue. 2/12

6:50 am-7:38 pm

1 stop12h 48m

Panama City Tocumen Intl

vie. 2/20

11:35 am-9:59 pm

1 stop10h 24m

$410

GreenvilleSan Salvador

GSP - SAL

GSPSAL

Greenville

jue. 11/20

6:22 pm-12:20 pm

2 stops18h 58m

San Salvador El Salvador Intl

jue. 11/27

1:20 pm-11:04 am

1 stop20h 44m

$411

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 55 results
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Best time to book a flight from Greenville to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Central America

What is the cheapest month to book a flight from Greenville to Central America?

Currently, April is the cheapest month in which you can book a flight from Greenville to Central America (average of $99). Flying from Greenville to Central America in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to CA?

Find hourly flight availability from Greenville to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 29, 2025.

When flying from Greenville to Central America, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 22% versus a flight at noon.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated octubre 29, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Greenville to Central America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Central America?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly out of when you book flights from Greenville to Central America.

  • How long is the flight from Greenville to Central America?

    For as low as $477, American Airlines can have you in Central America from Greenville in 7h. The distance from Greenville to Central America is about 1495 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Greenville to Central America one-way?

    The cheapest airlines for a one-way flight from Greenville to Central America are Delta ($189), American Airlines ($190), and United Airlines ($216).

  • What are the most popular routes from Greenville to Central America?

    The most popular route from Greenville to Central America is Greenville - Guatemala City La Aurora. You may also consider Greenville - San José Juan Santamaria Intl or Greenville - Panama City Tocumen Intl.

  • Can I find deals for flights from Greenville to Central America that include hotel bookings?

    Yes. In addition to deals on Greenville to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Central America.

  • Can I find deals for business class flights from Greenville to Central America?

    Yes. Cheapflights offers flight deals from Greenville to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Central America?

    Currently, April is the cheapest month in which you can book a flight from Greenville to Central America (average of $99). Flying from Greenville to Central America in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Central America

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Top 3 airlines flying from Greenville to Central America

Discover the top 3 airlines that operate flights from Greenville to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$575FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$352Average$611FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$367Average$588FlexibilityNo cancel feeOn-time71%

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