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Central America

$193+ Cheap flights from Greenville (GSP) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SJO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Greenville to Central America

Keep the following information in mind while searching for Greenville to Central America flight deals. Data was last updated September 11, 2025.

Round-trip from

$359
(Kiwi.com)

One-way from

$193
(American Airlines)

Popular in

November

Cheapest in

August

Average price

$578
From Greenville to Central America
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One-way flight from Greenville to Central America
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Highest demand for flights based on searches. 7% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Greenville to Central America

Cheapest flights from Greenville to Central America
Explore the most affordable flight options available from Greenville to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/38:03 pmGSP - SAP
2 stops18h 33mMultiple Airlines
Mon 11/1011:48 amSAP - GSP
1 stop6h 35mMultiple Airlines
Deal found 9/9$359
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/258:37 pmGSP - PTY
2 stops18h 54mAmerican Airlines
Wed 10/83:15 pmPTY - GSP
2 stops20h 15mAmerican Airlines
Deal found 9/11$408
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/227:44 pmGSP - SAL
2 stops17h 51mAmerican Airlines
Thu 10/212:35 pmSAL - GSP
1 stop9h 21mAmerican Airlines
Deal found 9/11$410
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/35:30 amGSP - SAP
1 stop7h 24mDelta
Mon 11/101:14 pmSAP - GSP
1 stop9h 41mDelta
Deal found 9/9$411
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:05 amGSP - PTY
1 stop8h 45mUnited Airlines
Wed 10/83:30 pmPTY - GSP
1 stop30h 09mUnited Airlines
Deal found 9/11$412
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/38:14 pmGSP - SAP
2 stops18h 56mAmerican Airlines
Tue 11/1112:48 pmSAP - GSP
1 stop10h 11mAmerican Airlines
Deal found 9/10$416
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:33 pmGSP - PTY
2 stops20h 58mAmerican Airlines
Wed 10/83:15 pmPTY - GSP
2 stops20h 15mAmerican Airlines
Deal found 9/11$428
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/38:14 pmGSP - SAP
2 stops18h 56mAmerican Airlines
Mon 11/103:15 pmSAP - GSP
1 stop7h 44mAmerican Airlines
Deal found 9/10$434
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/77:11 pmGSP - SAP
2 stops24h 59mAmerican Airlines
Fri 10/171:15 pmSAP - GSP
2 stops17h 09mAmerican Airlines
Deal found 9/10$464
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1910:35 amGSP - SJO
2 stops10h 55mSouthwest
Wed 12/39:00 amSJO - GSP
2 stops9h 50mSouthwest
Deal found 9/10$469
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/107:44 pmGSP - SAL
2 stops17h 51mAmerican Airlines
Mon 9/1512:35 pmSAL - GSP
2 stops20h 20mAmerican Airlines
Deal found 9/9$479
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/287:11 pmGSP - SAL
2 stops18h 29mAmerican Airlines
Fri 10/3112:41 pmSAL - GSP
2 stops22h 22mAmerican Airlines
Deal found 9/10$503

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Greenville to Central America that are best for you.

Fly from

Greenville

Fly to

Central America

Route

Depart

Return

Price

GreenvilleSan Pedro Sula

GSP - SAP

GSPSAP

Greenville

Mon 11/3

8:03 pm-1:36 pm

2 stops18h 33m

San Pedro Sula Ramon Villeda

Mon 11/10

11:48 am-7:23 pm

1 stop6h 35m

$359

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 1/21

6:45 am-2:02 pm

1 stop7h 17m

Panama City Tocumen Intl

Wed 2/4

3:27 pm-11:36 pm

1 stop8h 09m

$391

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 1/21

5:38 am-3:35 pm

1 stop9h 57m

Panama City Tocumen Intl

Wed 2/4

4:40 pm-12:15 am

1 stop7h 35m

$391

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 1/20

5:21 am-3:35 pm

2 stops10h 14m

Panama City Tocumen Intl

Tue 1/27

2:45 pm-12:15 am

1 stop9h 30m

$396

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Thu 9/25

8:37 pm-2:31 pm

2 stops18h 54m

Panama City Tocumen Intl

Wed 10/8

3:15 pm-12:30 pm

2 stops20h 15m

$408

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Thu 2/12

7:00 am-5:07 pm

1 stop10h 07m

Panama City Tocumen Intl

Fri 2/20

11:35 am-9:46 pm

1 stop10h 11m

$409

GreenvilleSan Salvador

GSP - SAL

GSPSAL

Greenville

Mon 9/22

7:44 pm-11:35 am

2 stops17h 51m

San Salvador El Salvador Intl

Thu 10/2

12:35 pm-11:56 pm

1 stop9h 21m

$410

GreenvilleSan Pedro Sula

GSP - SAP

GSPSAP

Greenville

Tue 11/4

5:30 am-11:54 am

1 stop7h 24m

San Pedro Sula Ramon Villeda

Tue 11/11

1:14 pm-11:55 pm

1 stop9h 41m

$411

GreenvilleSan Pedro Sula

GSP - SAP

GSPSAP

Greenville

Mon 11/3

5:30 am-11:54 am

1 stop7h 24m

San Pedro Sula Ramon Villeda

Mon 11/10

1:14 pm-11:55 pm

1 stop9h 41m

$411

GreenvilleSan Salvador

GSP - SAL

GSPSAL

Greenville

Thu 10/2

4:14 pm-11:35 am

2 stops21h 21m

San Salvador El Salvador Intl

Wed 10/15

12:41 pm-8:24 am

2 stops17h 43m

$411

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 54 results
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Best time to book a flight from Greenville to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Central America

What is the cheapest month to book a flight from Greenville to Central America?

Currently, September is the cheapest month in which you can book a flight from Greenville to Central America (average of $398). Flying from Greenville to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to CA?

Find hourly flight availability from Greenville to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Greenville to Central America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Greenville to Central America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Greenville to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Central America?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly out of when you book flights from Greenville to Central America.

  • How long is the flight from Greenville to Central America?

    For as low as $391, Delta can have you in Central America from Greenville in 7h 17m. The distance from Greenville to Central America is about 1792 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Greenville to Central America one-way?

    The cheapest airlines for a one-way flight from Greenville to Central America are American Airlines ($193), United Airlines ($211), and Delta ($216).

  • What are the most popular routes from Greenville to Central America?

    The most popular route from Greenville to Central America is Greenville - San José Juan Santamaria Intl. You may also consider Greenville - Belize City Philip S.W.Goldson or Greenville - Panama City Tocumen Intl.

  • Can I find deals for flights from Greenville to Central America that include hotel bookings?

    Yes. In addition to deals on Greenville to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Central America.

  • Can I find deals for business class flights from Greenville to Central America?

    Yes. Cheapflights offers flight deals from Greenville to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Central America?

    Currently, September is the cheapest month in which you can book a flight from Greenville to Central America (average of $398). Flying from Greenville to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Central America

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Top 3 airlines flying from Greenville to Central America

Discover the top 3 airlines that operate flights from Greenville to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$580FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$352Average$710FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$367Average$609FlexibilityNo cancel feeOn-time71%

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