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Biloxi

$249+ Cheap flights from Des Moines (DSM) to Biloxi, MS

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
jun 17 — jun 241
ter 6/17
ter 6/24
1 adult, Economy
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Cheap flight deals from Des Moines to Biloxi

Keep the following information in mind while searching for Des Moines to Biloxi flight deals. Data was last updated junho 12, 2025.

Round-trip from

$249
(American Airlines)

Popular in

February

Cheapest in

January

Average price

$367
From Des Moines to Biloxi
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($10 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
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Find flight deals from Des Moines to Biloxi

Cheapest flights from Des Moines to Biloxi
Explore the most affordable flight options available from Des Moines to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junho 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 9/165:34 pmDSM - GPT
1 stop5h 36mAmerican Airlines
seg 9/296:29 pmGPT - DSM
1 stop4h 44mAmerican Airlines
Deal found 6/12$249
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 9/1610:15 amDSM - GPT
2 stops11h 51mDelta
ter 9/306:00 pmGPT - DSM
1 stop4h 23mDelta
Deal found 6/12$254
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 7/122:57 pmDSM - GPT
1 stop6h 47mUnited Airlines
sex 7/185:25 pmGPT - DSM
1 stop4h 52mUnited Airlines
Deal found 6/11$306
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 6/257:30 amDSM - GPT
3 stops28h 45mMultiple Airlines
dom 6/2912:55 pmGPT - DSM
2 stops29h 16mMultiple Airlines
Deal found 6/10$609

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junho 12, 2025.
Use the filters below to find and compare flights from Des Moines to Biloxi that are best for you.

Fly from

Des Moines

Fly to

Biloxi

Route

Depart

Return

Price

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

ter 9/16

5:34 pm-11:10 pm

1 stop5h 36m

Gulfport Biloxi Regional

seg 9/29

6:29 pm-11:13 pm

1 stop4h 44m

$249

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

ter 9/16

10:15 am-10:06 pm

2 stops11h 51m

Gulfport Biloxi Regional

sáb 9/27

6:00 am-10:18 am

1 stop4h 18m

$254

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

sáb 7/12

2:57 pm-9:44 pm

1 stop6h 47m

Gulfport Biloxi Regional

sex 7/18

5:25 pm-10:17 pm

1 stop4h 52m

$306

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

qua 6/25

7:30 am-12:15 pm

3 stops28h 45m

Gulfport Biloxi Regional

dom 6/29

12:55 pm-6:11 pm

2 stops29h 16m

$609

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Best time to book a flight from Des Moines to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Biloxi

What is the cheapest month to book a flight from Des Moines to Biloxi?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Biloxi (average of $256). Flying from Des Moines to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to B1L?

Find hourly flight availability from Des Moines to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junho 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Biloxi as you normally would.

Rainfall in Biloxi by month

Plan your trip to Biloxi by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Biloxi ranges from 3.6 - 7.2 inches per month. July is typically the wettest month, when rainfall can reach 7.2 in. October is typically the driest time to visit Biloxi when rainfall is around 3.6 in.

Temperature in Biloxi by month

Plan your trip to Biloxi by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Biloxi, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 50.0 F).

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated junho 12, 2025.
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Biloxi?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Biloxi from Des Moines. Booking flights from Des Moines (DSM) to Biloxi should be relatively easy as there are 0 daily outbound flights to Biloxi from 4 different airlines.

  • Can I find deals for flights from Des Moines to Biloxi that include hotel bookings?

    Yes. In addition to deals on Des Moines to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Biloxi.

  • Can I find deals for business class flights from Des Moines to Biloxi?

    Yes. Cheapflights offers flight deals from Des Moines to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Biloxi?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Biloxi (average of $256). Flying from Des Moines to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 4 airlines flying from Des Moines to Biloxi

Discover the top 4 airlines that operate flights from Des Moines to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junho 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$380FlexibilityNo cancel feeOn-time71%
DeltaCheapest$244Average$371FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$259Average$421FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$312Average$406FlexibilityNo cancel feeOn-time63%

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