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$170+ Cheap flights from Knoxville (TYS) to Anaheim, CA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SNA
Feb 18 — Feb 251
Wed 2/18
Wed 2/25
1 adult, Economy
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Cheap flight deals from Knoxville to Anaheim

Keep the following information in mind while searching for Knoxville to Anaheim flight deals. Data was last updated January 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$294
(American Airlines)

One-way from

$170
(Delta)

Popular in

January

Cheapest in

May

Average price

$722
Provider with most accurate pricing for Knoxville McGhee Tyson-Los Angeles flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Los Angeles flights.
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From Knoxville McGhee Tyson to Anaheim
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One-way flight from Knoxville McGhee Tyson to Anaheim
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Highest demand for flights based on searches. 12% potential increase in price ($64 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Knoxville to Anaheim

Cheapest flights from Knoxville to Anaheim
Explore the most affordable flight options available from Knoxville to Anaheim. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 19, 2026.

This American Airlines deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:21 pm
TYS
-
SNA
1 stop9h 06m
American Airlines
Tue 3/317:48 pm
SNA
-
TYS
2 stops9h 54m
American Airlines
Deal found 1/17$294
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/304:25 pm
TYS
-
SNA
2 stops45h 02m
Frontier
Thu 2/511:53 am
SNA
-
TYS
1 stop24h 37m
Frontier
Deal found 1/18$322
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/27:35 am
TYS
-
SNA
1 stop7h 50m
Multiple Airlines
Fri 2/66:45 am
SNA
-
TYS
1 stop7h 05m
Multiple Airlines
Deal found 1/18$338
This Kiwi.com deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/110:00 am
TYS
-
SNA
1 stop26h 12m
Multiple Airlines
Thu 2/52:39 pm
SNA
-
TYS
2 stops21h 51m
Multiple Airlines
Deal found 1/17$348
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/132:49 pm
TYS
-
SNA
1 stop9h 28m
American Airlines
Tue 3/177:48 pm
SNA
-
TYS
2 stops9h 54m
American Airlines
Deal found 1/18$368
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:40 pm
TYS
-
SNA
1 stop7h 31m
Delta
Mon 4/209:45 pm
SNA
-
TYS
1 stop8h 37m
Delta
Deal found 1/19$369
This United Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/134:18 pm
TYS
-
SNA
1 stop8h 57m
United Airlines
Tue 3/1710:52 am
SNA
-
TYS
1 stop6h 55m
United Airlines
Deal found 1/18$399

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Anaheim that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 19, 2026.
Use the filters below to find and compare flights from Knoxville to Anaheim that are best for you.

Fly from

Knoxville

Fly to

Anaheim

Route

Depart

Return

Price

KnoxvilleSanta Ana

TYS - SNA

TYSSNA

Knoxville McGhee Tyson

Tue 3/24

4:29 pm-8:23 pm

1 stop6h 54m

Santa Ana J. Wayne/Orange Cnty

Tue 3/31

7:48 pm-8:42 am

2 stops9h 54m

$294

KnoxvilleSanta Ana

TYS - SNA

TYSSNA

Knoxville McGhee Tyson

Fri 1/30

4:25 pm-10:27 am

2 stops45h 02m

Santa Ana J. Wayne/Orange Cnty

Thu 2/5

11:53 am-3:30 pm

1 stop24h 37m

$322

KnoxvilleSanta Ana

TYS - SNA

TYSSNA

Knoxville McGhee Tyson

Mon 2/2

7:35 am-12:25 pm

1 stop7h 50m

Santa Ana J. Wayne/Orange Cnty

Fri 2/6

6:45 am-4:50 pm

1 stop7h 05m

$338

KnoxvilleSanta Ana

TYS - SNA

TYSSNA

Knoxville McGhee Tyson

Thu 4/16

5:40 pm-10:11 pm

1 stop7h 31m

Santa Ana J. Wayne/Orange Cnty

Mon 4/20

9:45 pm-9:22 am

1 stop8h 37m

$369

KnoxvilleSanta Ana

TYS - SNA

TYSSNA

Knoxville McGhee Tyson

Fri 3/13

4:18 pm-10:15 pm

1 stop8h 57m

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

10:52 am-8:47 pm

1 stop6h 55m

$399

KnoxvilleSanta Ana

TYS - SNA

TYSSNA

Knoxville McGhee Tyson

Wed 3/11

4:29 pm-10:45 pm

1 stop9h 16m

Santa Ana J. Wayne/Orange Cnty

Mon 3/16

3:24 pm-10:48 am

1 stop16h 24m

$412

KnoxvilleSanta Ana

TYS - SNA

TYSSNA

Knoxville McGhee Tyson

Thu 4/16

5:40 pm-10:11 pm

1 stop7h 31m

$170

KnoxvilleSanta Ana

TYS - SNA

TYSSNA

Knoxville McGhee Tyson

Wed 4/15

5:44 am-12:05 pm

1 stop9h 21m

$170

KnoxvilleSanta Ana

TYS - SNA

TYSSNA

Knoxville McGhee Tyson

Sat 4/18

5:30 am-11:47 am

1 stop9h 17m

$170

KnoxvilleSanta Ana

TYS - SNA

TYSSNA

Knoxville McGhee Tyson

Mon 4/13

5:40 pm-10:11 pm

1 stop7h 31m

$170

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/16

Showing 1-10 of 18 results
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Best time to book a flight from Knoxville to Anaheim

Have a flexible travel schedule? Discover the best time to fly to Anaheim from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Anaheim

How far ahead should I book a flight from Knoxville to Anaheim?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Anaheim. Price data was last updated on January 16, 2026.

To ensure you get the cheapest price possible for a flight from Knoxville to Anaheim, you should look to book at least 88 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to Anaheim?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Anaheim (average of $142). Flying from Knoxville to Anaheim in September is currently the most expensive (average of $270). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Anaheim

Get insights into the airlines that provide service to Anaheim. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Anaheim. Reviews last updated January 19, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Anaheim have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,080 reviews

Comfort

7.9

Overall

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
7.9
Good
8,080 reviews
Delta
7.9
Good
8,080 reviews

Comfort

7.9

Overall

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
9,183 reviews
Delta
7.9
Good
8,080 reviews

Comfort

7.9

Overall

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
11,164 reviews
Delta
7.9
Good
8,080 reviews

Comfort

7.9

Overall

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Anaheim. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Anaheim?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to Anaheim. 4 airlines have flights from McGhee Tyson to Anaheim on a regular basis. Booking flights from Knoxville McGhee Tyson to Anaheim should not be difficult; the airport handles an average of 0 outbound flights to Anaheim per day.

  • How long is the flight from Knoxville to Anaheim?

    American Airlines and Frontier can get you from Knoxville to Anaheim in just under 6h 54m. Your travel time can differ by up to 38h 08m. The distance from Knoxville to Anaheim is about 1918 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Knoxville to Anaheim that include hotel bookings?

    Yes. In addition to deals on Knoxville to Anaheim flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Anaheim?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Anaheim.

  • Can I find deals for business class flights from Knoxville to Anaheim?

    Yes. Cheapflights offers flight deals from Knoxville to Anaheim by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Anaheim?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Anaheim (average of $142). Flying from Knoxville to Anaheim in September is currently the most expensive (average of $270). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Anaheim

Discover the top 4 airlines that operate flights from Knoxville to Anaheim. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$142Average$302FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$219Average$469FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$269Average$420FlexibilityNo cancel feeOn-time71%
DeltaCheapest$282Average$405FlexibilityNo cancel feeOn-timeN/A

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