What are the cheapest airlines to fly from Knoxville to Anaheim one-way?

$167 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $177 and $269, respectively.

In terms of precipitation, rainfall in Anaheim ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Anaheim when rainfall is around 0.0 in.

If weather is an important factor for your trip to Anaheim, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular airlines that fly from Knoxville to Anaheim?

When booking a flight from Knoxville to Anaheim, you may want to consider flying on American Airlines, United Airlines or Southwest as they are the most popular for this route.

What is the cheapest time of day to fly from TYS to AN4?

When flying from Knoxville to Anaheim, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly from for flights from Knoxville to Anaheim?

Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to Anaheim. 5 airlines have flights from McGhee Tyson to Anaheim on a regular basis. Booking flights from Knoxville McGhee Tyson to Anaheim should not be difficult; the airport handles an average of 0 outbound flights to Anaheim per day.

Can I find deals for flights from Knoxville to Anaheim that include hotel bookings?

Yes. In addition to deals on Knoxville to Anaheim flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to Anaheim?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Anaheim.

Can I find deals for business class flights from Knoxville to Anaheim?

Yes. Cheapflights offers flight deals from Knoxville to Anaheim by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Find flight deals from Knoxville to Anaheim

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Popular in	January
Cheapest in	May
Average price	$491

Provider with most accurate pricing for Knoxville McGhee Tyson-Los Angeles flight deals.

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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Los Angeles flights.

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Highest demand for flights based on searches. 6% potential increase in price ($40 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).

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Average for round-trip flights in September 2026

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Reviews of airlines servicing Anaheim

See what other customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to Anaheim have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,198 reviews

Reviews

1 / 20

10.0

Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Southwest

8.0

Very good

4,198 reviews

Southwest

8.0

Very good

4,198 reviews

Reviews

1 / 20

10.0

Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Delta

7.8

Good

8,591 reviews

Southwest

8.0

Very good

4,198 reviews

Reviews

1 / 20

10.0

Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

United Airlines

7.4

Good

10,226 reviews

Southwest

8.0

Very good

4,198 reviews

Reviews

1 / 20

10.0

Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

American Airlines

7.0

Good

12,076 reviews

Southwest

8.0

Very good

4,198 reviews

Reviews

1 / 20

10.0

Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Related info for your journey

What airport do you fly from for flights from Knoxville to Anaheim?
Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to Anaheim. 5 airlines have flights from McGhee Tyson to Anaheim on a regular basis. Booking flights from Knoxville McGhee Tyson to Anaheim should not be difficult; the airport handles an average of 0 outbound flights to Anaheim per day.
What are the cheapest airlines to fly from Knoxville to Anaheim one-way?
$167 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $177 and $269, respectively.
Can I find deals for flights from Knoxville to Anaheim that include hotel bookings?
Yes. In addition to deals on Knoxville to Anaheim flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Anaheim?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Anaheim.
Can I find deals for business class flights from Knoxville to Anaheim?
Yes. Cheapflights offers flight deals from Knoxville to Anaheim by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top 5 airlines flying from Knoxville to Anaheim

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$142	Average$325	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$186	Average$462	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$288	Average$489	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$298	Average$533	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$362	Average$509	FlexibilityNo cancel fee	On-time63%

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Find cheap flights from Knoxville to Anaheim with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Knoxville to Anaheim

Most accurate provider

Most trusted provider

Popular in

Cheapest in

Average price

Reviews of airlines servicing Anaheim

See what other customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to Anaheim have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Knoxville to Anaheim?

What are the cheapest airlines to fly from Knoxville to Anaheim one-way?

Can I find deals for flights from Knoxville to Anaheim that include hotel bookings?

How can I find direct flights from Knoxville to Anaheim?

Can I find deals for business class flights from Knoxville to Anaheim?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Anaheim

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Anaheim by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Knoxville to Anaheim by cabin class

Find flights from Knoxville to Anaheim, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Knoxville and Anaheim flights

Browse other Knoxville and Anaheim flight options. Last updated on September 23, 2026.

Other flights from Knoxville

Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 23, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

Knoxville to Anaheim flights

Consider these flights traveling from Knoxville to Anaheim.

Top 5 airlines flying from Knoxville to Anaheim

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Cheap flights from Knoxville (TYS) to Anaheim, CA

Find cheap flights from Knoxville to Anaheim with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Knoxville to Anaheim

Most accurate provider

Most trusted provider

Popular in

Cheapest in

Average price

Reviews of airlines servicing Anaheim

See what other customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to Anaheim have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Knoxville to Anaheim?

What are the cheapest airlines to fly from Knoxville to Anaheim one-way?

Can I find deals for flights from Knoxville to Anaheim that include hotel bookings?

How can I find direct flights from Knoxville to Anaheim?

Can I find deals for business class flights from Knoxville to Anaheim?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Anaheim

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Anaheim by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Knoxville to Anaheim by cabin class

Find flights from Knoxville to Anaheim, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Knoxville and Anaheim flights

Browse other Knoxville and Anaheim flight options. Last updated on September 23, 2026.

Other flights from Knoxville

Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 23, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

Knoxville to Anaheim flights

Consider these flights traveling from Knoxville to Anaheim.

Top 5 airlines flying from Knoxville to Anaheim

100% Free

Book with Flexibility

Travel Smart