What are the cheapest airlines flying from Santa Ana to St. Louis round-trip?

Frontier, at $138, was found to be the cheapest airline from Santa Ana to St. Louis.Alternate airlines to your destination round-trip include Delta and Southwest. Frontier is priced at 70% lower than the current average price of a flight leaving 3 months from now.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular airlines that fly from Santa Ana to St. Louis?

Consider American Airlines, Delta or Frontier when booking your flight. These represent the most popular airlines when flying from Santa Ana to St. Louis.

What is the cheapest day to fly round-trip from Santa Ana to St. Louis?

Leaving on a Monday is a viable option for saving on travel. Heavily demanded days of the week can typically drive up the prices you see. Booking your travel for a less competitive day can save up to 31% on the overall cost on flights from Santa Ana to St. Louis.

How far in advance should I book a flight from Santa Ana to St. Louis?

Find a great deal and save up to 310% by booking at least 61 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Santa Ana to St. Louis within the next two weeks, with the cheapest ticket starting at $406.

What is the cheapest month to fly from Santa Ana to St. Louis?

August can be a great time to fly to St. Louis from Santa Ana with a flight ticket averaging about $400. Cheapflights users have found deals in the month of August for as cheap as $214. The most expensive prices can be found in the month of December.

Can I find deals for flights from Santa Ana to St. Louis that include hotel bookings?

Yes. In addition to deals on Santa Ana to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santa Ana to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to St. Louis.

Can I find deals for business class flights from Santa Ana to St. Louis?

Yes. Cheapflights offers flight deals from Santa Ana to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$110+ Flights from Santa Ana to St. Louis

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Cheap flight deals from Santa Ana to St. Louis

Round-trip from	$169 (FlightHub)
One-way from	$110 (Frontier)
Popular in	January
Cheapest in	October
Average price	$441

From Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis

Search Deals

One-way flight from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 8% potential increase in price ($42 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Santa Ana to St. Louis

Cheapest flights from Santa Ana to St. Louis
Explore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Fri 10/241:06 pmSNA - STL

1 stop24h 50mFrontier

Sun 10/267:52 pmSTL - SNA

1 stop17h 24mFrontier

Deal found 8/15

$169

Wed 9/1012:58 pmSNA - STL

1 stop18h 08mFrontier

Mon 9/157:55 pmSTL - SNA

1 stop18h 18mFrontier

Deal found 8/16

$175

Fri 10/242:35 pmSNA - STL

2 stops16h 32mFrontier

Mon 10/2712:38 pmSTL - SNA

1 stop8h 30mFrontier

Deal found 8/15

$193

Wed 10/112:58 pmSNA - STL

1 stop18h 08mFrontier

Sun 10/510:39 amSTL - SNA

2 stops27h 36mFrontier

Deal found 8/13

$202

Wed 9/2412:58 pmSNA - STL

1 stop18h 08mFrontier

Sun 9/287:55 pmSTL - SNA

1 stop17h 12mFrontier

Deal found 8/15

$209

Mon 9/811:52 amSNA - STL

1 stop19h 14mFrontier

Mon 9/157:55 pmSTL - SNA

1 stop18h 18mFrontier

Deal found 8/16

$212

Thu 8/2111:49 amSNA - STL

1 stop19h 22mFrontier

Sun 8/246:47 pmSTL - SNA

1 stop25h 32mFrontier

Deal found 8/15

$223

Tue 9/92:15 pmSNA - STL

2 stops16h 51mMultiple Airlines

Mon 9/157:55 pmSTL - SNA

1 stop18h 18mMultiple Airlines

Deal found 8/16

$227

Thu 9/113:29 pmSNA - STL

2 stops15h 37mFrontier

Mon 9/159:29 pmSTL - SNA

2 stops16h 44mFrontier

Deal found 8/16

$228

Mon 9/81:00 pmSNA - STL

2 stops18h 06mMultiple Airlines

Mon 9/157:55 pmSTL - SNA

1 stop18h 18mMultiple Airlines

Deal found 8/16

$232

Best flights from Santa Ana to St. Louis
Discover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 16, 2025.

Fri 10/241:06 pmSNA - STL

1 stop24h 50mFrontier

Sun 10/267:52 pmSTL - SNA

1 stop17h 24mFrontier

Deal found 8/15

$169

Fri 11/1412:01 pmSNA - STL

1 stop19h 06mFrontier

Mon 11/172:42 pmSTL - SNA

1 stop6h 06mFrontier

Deal found 8/14

$169

Fri 10/2412:01 pmSNA - STL

1 stop19h 06mFrontier

Mon 10/2712:38 pmSTL - SNA

1 stop8h 30mFrontier

Deal found 8/14

$169

Thu 11/138:16 pmSNA - STL

1 stop15h 41mFrontier

Mon 11/177:45 pmSTL - SNA

1 stop19h 50mFrontier

Deal found 8/14

$169

Fri 9/128:38 pmSNA - STL

1 stop17h 25mFrontier

Mon 9/157:55 pmSTL - SNA

1 stop18h 18mFrontier

Deal found 8/14

$169

Thu 9/117:16 pmSNA - STL

1 stop16h 37mFrontier

Mon 9/157:55 pmSTL - SNA

1 stop18h 18mFrontier

Deal found 8/14

$169

Wed 9/1012:58 pmSNA - STL

1 stop18h 08mFrontier

Mon 9/157:55 pmSTL - SNA

1 stop18h 18mFrontier

Deal found 8/14

$175

Sat 9/1312:58 pmSNA - STL

1 stop18h 08mFrontier

Mon 9/157:55 pmSTL - SNA

1 stop18h 18mFrontier

Deal found 8/14

$175

Mon 10/2712:01 pmSNA - STL

1 stop19h 06mFrontier

Sun 11/27:45 pmSTL - SNA

1 stop17h 31mFrontier

Deal found 8/14

$175

Last-minute flights from Santa Ana to St. Louis
Discover last-minute flight deals from Santa Ana to St. Louis. Data last updated August 16, 2025 and is based on user searches.

Thu 8/2111:49 amSNA - STL

1 stop19h 22mFrontier

Sun 8/246:47 pmSTL - SNA

1 stop25h 32mFrontier

Deal found 8/15

$223

Thu 8/216:45 amSNA - STL

2 stops24h 26mMultiple Airlines

Sun 8/246:47 pmSTL - SNA

1 stop25h 32mMultiple Airlines

Deal found 8/15

$369

Fri 8/226:45 amSNA - STL

1 stop8h 49mAlaska Airlines

Tue 8/263:35 pmSTL - SNA

1 stop8h 07mAlaska Airlines

Deal found 8/15

$800

Fri 8/2212:45 pmSNA - STL

1 stop9h 14mAlaska Airlines

Mon 8/253:35 pmSTL - SNA

1 stop8h 55mAlaska Airlines

Deal found 8/15

$840

Sat 8/2312:04 pmSNA - STL

1 stop19h 07mMultiple Airlines

Sun 8/312:30 pmSTL - SNA

1 stop22h 59mMultiple Airlines

Deal found 8/14

$291

Sat 8/236:53 amSNA - STL

1 stop15h 00mUnited Airlines

Sun 8/318:20 amSTL - SNA

2 stops14h 08mUnited Airlines

Deal found 8/14

$657

Sat 8/236:45 amSNA - STL

1 stop8h 49mAlaska Airlines

Tue 8/263:35 pmSTL - SNA

1 stop8h 07mAlaska Airlines

Deal found 8/15

$760

Sat 8/231:10 pmSNA - STL

2 stops8h 14mDelta

Sun 8/316:00 amSTL - SNA

2 stops7h 53mDelta

Deal found 8/14

$1,527

Tue 8/267:00 amSNA - STL

1 stop7h 00mSouthwest

Tue 8/265:25 pmSTL - SNA

1 stop5h 35mSouthwest

Deal found 8/16

$761

Mon 9/811:52 amSNA - STL

1 stop19h 14mFrontier

Mon 9/157:55 pmSTL - SNA

1 stop18h 18mFrontier

Deal found 8/16

$212

Mon 9/81:00 pmSNA - STL

2 stops18h 06mMultiple Airlines

Mon 9/157:55 pmSTL - SNA

1 stop18h 18mMultiple Airlines

Deal found 8/16

$232

Tue 9/92:15 pmSNA - STL

2 stops16h 51mMultiple Airlines

Mon 9/157:55 pmSTL - SNA

1 stop18h 18mMultiple Airlines

Deal found 8/16

$227

One-way flights from Santa Ana to St. Louis
Search for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 16, 2025.

Fri 9/58:38 pmSNA - STL

2 stops10h 28mFrontier

Deal found 8/15

$110

Sun 8/241:03 pmSNA - STL

1 stop18h 08mFrontier

Deal found 8/15

$112

Sun 9/73:29 pmSNA - STL

2 stops15h 37mFrontier

Deal found 8/14

$115

Fri 10/171:06 pmSNA - STL

1 stop5h 58mFrontier

Deal found 8/15

$117

Mon 10/131:06 pmSNA - STL

1 stop5h 58mFrontier

Deal found 8/15

$122

Tue 1/612:37 pmSNA - STL

1 stop9h 22mAlaska Airlines

Deal found 8/16

$145

Thu 8/214:37 pmSNA - STL

2 stops14h 34mFrontier

Deal found 8/15

$155

Mon 10/201:06 pmSNA - STL

1 stop5h 58mFrontier

Deal found 8/16

$157

Fri 8/2210:52 amSNA - STL

2 stops20h 19mFrontier

Deal found 8/14

$160

Thu 8/2812:24 pmSNA - STL

1 stop23h 08mSpirit Airlines

Deal found 8/14

$162

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 10/24

1:06 pm-3:56 pm

1 stop24h 50m

Lambert-St Louis

Sun 10/26

7:52 pm-11:16 am

1 stop17h 24m

$169

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 11/14

12:01 pm-9:07 am

1 stop19h 06m

Lambert-St Louis

Mon 11/17

2:42 pm-6:48 pm

1 stop6h 06m

$169

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 10/24

12:01 pm-9:07 am

1 stop19h 06m

Lambert-St Louis

Mon 10/27

12:38 pm-7:08 pm

1 stop8h 30m

$169

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 11/13

8:16 pm-1:57 pm

1 stop15h 41m

Lambert-St Louis

Mon 11/17

7:45 pm-1:35 pm

1 stop19h 50m

$169

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 9/12

8:38 pm-4:03 pm

1 stop17h 25m

Lambert-St Louis

Mon 9/15

7:55 pm-12:13 pm

1 stop18h 18m

$169

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 9/11

7:16 pm-1:53 pm

1 stop16h 37m

Lambert-St Louis

Mon 9/15

7:55 pm-12:13 pm

1 stop18h 18m

$169

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 9/10

12:58 pm-9:06 am

1 stop18h 08m

Lambert-St Louis

Mon 9/15

7:55 pm-12:13 pm

1 stop18h 18m

$175

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Sat 9/13

12:58 pm-9:06 am

1 stop18h 08m

Lambert-St Louis

Mon 9/15

7:55 pm-12:13 pm

1 stop18h 18m

$175

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 10/27

12:01 pm-9:07 am

1 stop19h 06m

Lambert-St Louis

Sun 11/2

7:45 pm-11:16 am

1 stop17h 31m

$175

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 9/5

8:38 pm-9:06 am

2 stops10h 28m

$110

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 15 results

Best time to book a flight from Santa Ana to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Ana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to St. Louis

What is the cheapest month to book a flight from Santa Ana to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Santa Ana to St. Louis (average of $311). Flying from Santa Ana to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to STL?

It’s optimal to fly from Santa Ana to St. Louis in the evening. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Santa Ana to St. Louis?

Travelers seeking maximum savings on their Santa Ana to St. Louis flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Santa Ana to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,246 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

8.0

Very good

7,985 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

8,916 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Frontier

5.8

Fair

3,211 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

What are the cheapest airlines flying from Santa Ana to St. Louis round-trip?
Frontier, at $138, was found to be the cheapest airline from Santa Ana to St. Louis.Alternate airlines to your destination round-trip include Delta and Southwest. Frontier is priced at 70% lower than the current average price of a flight leaving 3 months from now.
Can I find deals for flights from Santa Ana to St. Louis that include hotel bookings?
Yes. In addition to deals on Santa Ana to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santa Ana to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to St. Louis.
Can I find deals for business class flights from Santa Ana to St. Louis?
Yes. Cheapflights offers flight deals from Santa Ana to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Santa Ana to St. Louis (average of $311). Flying from Santa Ana to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

O'Fallon

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Maryland Heights

Collinsville

Eureka

St. Peters

Glencoe

Alton

Chesterfield

Farmington

Festus

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Santa Ana to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$138	Average$302	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$248	Average$490	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$326	Average$480	FlexibilityNo cancel fee	On-time63%
American Airlines	Cheapest$342	Average$466	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$352	Average$467	FlexibilityNo cancel fee	On-time69%

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$110+ Cheap flights from Santa Ana to St. Louis (SNA - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santa Ana to St. Louis with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Santa Ana to St. Louis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santa Ana to St. Louis

Cheapest flights from Santa Ana to St. LouisExplore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Explore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to St. Louis that are best for you.

Best time to book a flight from Santa Ana to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Ana with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to St. Louis

What is the cheapest month to book a flight from Santa Ana to St. Louis?

What is the cheapest time of day to fly from SNA to STL?

Find hourly flight availability from Santa Ana to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 16, 2025.

What is the cheapest day to fly from Santa Ana to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Santa Ana to St. Louis. Price data was last updated on December 16, 2024.

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Santa Ana to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Santa Ana to St. Louis round-trip?

Can I find deals for flights from Santa Ana to St. Louis that include hotel bookings?

How can I find direct flights from Santa Ana to St. Louis?

Can I find deals for business class flights from Santa Ana to St. Louis?

What is the cheapest month to book a flight from Santa Ana to St. Louis?

Traveling to a place near St. Louis?

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Alternative routes for Santa Ana to St. Louis

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Top 5 airlines flying from Santa Ana to St. Louis

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Cheapest flights from Santa Ana to St. Louis
Explore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.