$146+ Cheap flights from Santa Ana, CA to St. Louis (SNA - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — STL
Nov 8 — Nov 151
Round-trip
1 adult, Economy
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Find cheap flights from Santa Ana to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to St. Louis
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Cheapest flights from Santa Ana to St. LouisExplore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 9, 2026.
Explore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 9, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:51 pm -
1 stop12h 03m
Mon 11/91:28 pm -
1 stop7h 43m
Deal found 10/6![Frontier logo]()
$266
This Frontier deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:38 am -
1 stop5h 36m
Mon 11/161:28 pm -
1 stop7h 43m
Deal found 10/7![Frontier logo]()
$274
This Cheapflightsfares deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:38 am -
1 stop5h 36m
Mon 11/91:28 pm -
1 stop7h 43m
Deal found 10/6![Frontier logo]()
$283
This Expedia deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:48 am -
1 stop15h 11m
Mon 11/91:28 pm -
1 stop7h 43m
Deal found 10/5![Multiple Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:01 pm -
2 stops47h 22m
Mon 11/91:28 pm -
1 stop7h 43m
Deal found 10/5![Frontier logo]()
$319
This Priceline deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:59 pm -
1 stop9h 00m
Fri 10/301:28 pm -
1 stop7h 43m
Deal found 10/5![Multiple Airlines logo]()
$320
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:35 pm -
1 stop5h 40m
Tue 11/105:55 am -
1 stop6h 55m
Deal found 10/6![Southwest logo]()
$329
Best flights from Santa Ana to St. LouisDiscover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 9, 2026.
Discover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 9, 2026.
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:55 pm -
1 stop6h 00m
Fri 11/275:05 am -
2 stops7h 15m
Deal found 10/6![Southwest logo]()
$382
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:00 pm -
2 stops12h 32m
Mon 11/98:00 am -
1 stop8h 14m
Deal found 10/7![United Airlines logo]()
$461
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/211:26 pm -
1 stop8h 02m
Fri 1/86:30 am -
1 stop8h 15m
Deal found 10/4![Delta logo]()
$473
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:00 am -
1 stop8h 20m
Thu 12/176:10 am -
2 stops7h 20m
Deal found 10/9![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:36 pm -
2 stops13h 36m
Thu 10/295:00 am -
2 stops11h 59m
Deal found 10/6![United Airlines logo]()
$486
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:50 am -
2 stops6h 35m
Thu 11/198:25 am -
2 stops8h 20m
Deal found 10/6![Southwest logo]()
$444
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:30 am -
2 stops8h 45m
Mon 11/912:30 pm -
2 stops8h 50m
Deal found 10/6![Southwest logo]()
$460
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:30 am -
2 stops8h 45m
Mon 11/912:30 pm -
2 stops8h 50m
Deal found 10/6![Southwest logo]()
$460
Last-minute flights from Santa Ana to St. LouisDiscover last-minute flight deals from Santa Ana to St. Louis. Data last updated October 9, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to St. Louis. Data last updated October 9, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:59 pm -
1 stop9h 00m
Fri 10/301:28 pm -
1 stop7h 43m
Deal found 10/5![Multiple Airlines logo]()
$320
This Expedia deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:48 am -
1 stop15h 11m
Mon 11/91:28 pm -
1 stop7h 43m
Deal found 10/5![Multiple Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:01 pm -
2 stops47h 22m
Mon 11/91:28 pm -
1 stop7h 43m
Deal found 10/5![Frontier logo]()
$319
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:35 pm -
1 stop5h 40m
Tue 11/105:55 am -
1 stop6h 55m
Deal found 10/6![Southwest logo]()
$329
This Cheapflightsfares deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:51 pm -
1 stop12h 03m
Mon 11/91:28 pm -
1 stop7h 43m
Deal found 10/6![Frontier logo]()
$266
This Cheapflightsfares deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:38 am -
1 stop5h 36m
Mon 11/91:28 pm -
1 stop7h 43m
Deal found 10/6![Frontier logo]()
$283
This Frontier deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:38 am -
1 stop5h 36m
Mon 11/161:28 pm -
1 stop7h 43m
Deal found 10/7![Frontier logo]()
$274
One-way flights from Santa Ana to St. LouisSearch for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 9, 2026.
Search for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 9, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:08 pm -
1 stop18h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Frontier logo]()
$146
This Cheapflightsfares deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:38 am -
1 stop5h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Frontier logo]()
$150
This Cheapflightsfares deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:39 pm -
1 stop17h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Frontier logo]()
$164
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:10 pm -
1 stop4h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Southwest logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:30 am -
2 stops32h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:38 am -
2 stops22h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Frontier logo]()
$178
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:00 pm -
1 stop5h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Southwest logo]()
$200
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/319:35 am -
2 stops9h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Southwest logo]()
$205
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2011:33 am -
1 stop8h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![American Airlines logo]()
$215
This Priceline deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:38 am -
1 stop5h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Frontier logo]()
$216
Find flight deals from Santa Ana to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $266 (Cheapflightsfares) |
One-way from | $146 (Cheapflightsfares) |
Popular in | August |
Cheapest in | October |
Average price | $398 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 9, 2026.
Use the filters below to find and compare flights from Santa Ana to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 10/22
4:08 pm-12:35 pm
1 stop18h 27m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$146
Quickest round-trip
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Tue 11/3
4:10 pm-11:05 pm
1 stop4h 55m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$165
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 11/19
8:00 am-4:31 pm
1 stop6h 31m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$165
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 11/19
11:38 am-12:25 pm
2 stops22h 47m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$178
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Mon 12/21
1:26 pm-11:28 pm
1 stop8h 02m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$215
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Fri 11/6
11:10 am-11:24 pm
2 stops10h 14m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$217
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Wed 10/21
7:30 am-11:13 pm
2 stops37h 43m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$237
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Tue 10/20
7:30 am-5:40 pm
2 stops32h 10m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$237
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Tue 12/29
8:05 am-7:10 pm
2 stops9h 05m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$264
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Tue 10/20
1:35 pm-11:30 pm
1 stop7h 55m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$304
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to St. Louis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Ana with our price prediction graph.
SNA-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to St. Louis
Prices
More
What is the cheapest month to book a flight from Santa Ana, California to St. Louis?
Currently, October is the cheapest month in which you can book a flight from Santa Ana, California to St. Louis (average of $398). Flying from Santa Ana, California to St. Louis in August is currently the most expensive (average of $831). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Ana, California to St. Louis?
Airfare is below average for this route at the moment.
Santa Ana, California to St. Louis flights typically cost between $328 and $456 in November.The cheapest round-trip price found within the last 5 days was $266 on Frontier (Nov 5-Nov 9).
What’s the top layover airport for flights from Santa Ana, California to St. Louis?
Share of 1-stop round-trip flights from Santa Ana, California to St. Louis chosen by Cheapflights users in the past 12 months, using the same layover each way.
Las Vegas (LAS) – chosen by Cheapflights users on 83% of 1-stop itineraries from Santa Ana, California to St. Louis on Cheapflights.
What’s the cheapest layover airport for flights from Santa Ana, California to St. Louis?
Average round-trip fare for 1-stop flights from Santa Ana, California to St. Louis, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Phoenix (PHX) is the most affordable 1-stop option, with an average round-trip price of $541.
What’s the fastest layover option from Santa Ana, California to St. Louis?
Shortest average travel time for 1-stop one-way flights from Santa Ana, California to St. Louis, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Phoenix (PHX) have the shortest average one-way travel time for 1-stop routes: 5h 25m.
Which airport typically offers the quickest layover for flights from Santa Ana, California to St. Louis?
Average layover duration for 1-stop one-way flights from Santa Ana, California to St. Louis, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Phoenix (PHX) offer the fastest connection on this route, with an average layover time of 0h 50m.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 9, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Santa Ana to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
7.9
Entertainment
7.4
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Overall
7.9
Entertainment
7.4
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Overall
7.9
Entertainment
7.4
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Overall
7.9
Entertainment
7.4
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Overall
7.9
Entertainment
7.4
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Chesterfield
Maryland Heights
Collinsville
Edwardsville
Glencoe
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Santa Ana and St. Louis flights
Browse other Santa Ana and St. Louis flight options. Last updated on October 9, 2026.
Other flights from Santa Ana
Browse through other flights departing from Santa Ana. Flights are based on user searches made on Cheapflights and were last updated on October 9, 2026.
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Other flights to St. Louis
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Top 4 airlines flying from Santa Ana to St. Louis
Discover the top 4 airlines that operate flights from Santa Ana to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$463 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$328 | Average$496 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$356 | Average$496 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$361 | Average$547 | FlexibilityNo cancel fee | On-time63% |