How long is the flight from Santa Ana to St. Louis?

Airlines like Frontier fly from Santa Ana to St. Louis in about 16h 47m. The time it takes to get you to your destination can typically vary by up to . The distance between Santa Ana and St. Louis is about 1565 mi.

What are the cheapest airlines flying from Santa Ana to St. Louis round-trip?

Frontier, at $138, was found to be the cheapest airline from Santa Ana to St. Louis.Alternate airlines to your destination round-trip include Delta and Southwest. Frontier is priced at 69% lower than the current average price of a flight leaving 3 months from now.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular airlines that fly from Santa Ana to St. Louis?

Consider American Airlines, Delta or Frontier when booking your flight. These represent the most popular airlines when flying from Santa Ana to St. Louis.

Can I find deals for flights from Santa Ana to St. Louis that include hotel bookings?

Yes. In addition to deals on Santa Ana to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santa Ana to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to St. Louis.

Can I find deals for business class flights from Santa Ana to St. Louis?

Yes. Cheapflights offers flight deals from Santa Ana to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$72+ Flights from Santa Ana to St. Louis

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Cheap flight deals from Santa Ana to St. Louis

Round-trip from	$144 (Frontier)
One-way from	$72 (Cheapflightsfares)
Popular in	January
Cheapest in	August
Average price	$490

From Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis

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One-way flight from Santa Ana J. Wayne/Orange Cnty to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 5% potential increase in price ($26 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from Santa Ana to St. Louis

Cheapest flights from Santa Ana to St. Louis
Explore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2025.

Fri 10/242:35 pmSNA - STL

1 stop5h 39mFrontier

Mon 10/2712:38 pmSTL - SNA

1 stop8h 30mFrontier

Deal found 9/16

$144

Sat 11/82:20 pmSNA - STL

1 stop16h 47mFrontier

Sun 11/167:45 pmSTL - SNA

1 stop17h 31mFrontier

Deal found 9/18

$154

Sat 9/2712:58 pmSNA - STL

1 stop18h 08mFrontier

Sun 9/282:38 pmSTL - SNA

1 stop23h 37mFrontier

Deal found 9/16

$156

Wed 10/292:20 pmSNA - STL

1 stop16h 47mFrontier

Sat 11/18:40 pmSTL - SNA

1 stop17h 36mFrontier

Deal found 9/18

$165

Tue 9/3012:58 pmSNA - STL

1 stop18h 08mFrontier

Wed 10/17:55 pmSTL - SNA

1 stop17h 12mFrontier

Deal found 9/17

$188

Tue 11/42:20 pmSNA - STL

1 stop16h 47mFrontier

Wed 11/57:45 pmSTL - SNA

1 stop17h 31mFrontier

Deal found 9/16

$192

Tue 11/42:20 pmSNA - STL

1 stop16h 47mFrontier

Fri 11/77:45 pmSTL - SNA

1 stop19h 50mFrontier

Deal found 9/16

$197

Sat 10/182:20 pmSNA - STL

1 stop16h 47mFrontier

Mon 10/2012:38 pmSTL - SNA

1 stop8h 30mFrontier

Deal found 9/18

$198

Sun 9/2811:52 amSNA - STL

1 stop19h 14mFrontier

Sat 10/257:52 pmSTL - SNA

1 stop17h 24mFrontier

Deal found 9/18

$200

Fri 11/147:38 pmSNA - STL

2 stops35h 29mFrontier

Mon 11/177:45 pmSTL - SNA

1 stop19h 50mFrontier

Deal found 9/16

$202

Tue 11/42:20 pmSNA - STL

1 stop16h 47mMultiple Airlines

Thu 11/66:22 pmSTL - SNA

2 stops24h 29mMultiple Airlines

Deal found 9/16

$204

Best flights from Santa Ana to St. Louis
Discover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2025.

Wed 10/292:20 pmSNA - STL

1 stop16h 47mFrontier

Sat 11/18:40 pmSTL - SNA

1 stop17h 36mFrontier

Deal found 9/18

$165

Fri 10/311:52 amSNA - STL

1 stop19h 14mMultiple Airlines

Tue 10/77:52 pmSTL - SNA

2 stops28h 11mMultiple Airlines

Deal found 9/18

$263

Wed 10/2211:48 amSNA - STL

1 stop6h 35mDelta

Mon 10/275:15 pmSTL - SNA

1 stop7h 13mDelta

Deal found 9/16

$333

Wed 10/2912:45 pmSNA - STL

2 stops9h 25mSouthwest

Sat 11/19:00 amSTL - SNA

2 stops11h 25mSouthwest

Deal found 9/18

$364

Sun 9/2811:52 amSNA - STL

1 stop19h 14mFrontier

Sat 10/257:52 pmSTL - SNA

1 stop17h 24mFrontier

Deal found 9/18

$200

Tue 11/42:20 pmSNA - STL

1 stop16h 47mFrontier

Thu 11/67:45 pmSTL - SNA

1 stop17h 31mFrontier

Deal found 9/16

$224

Sat 11/85:46 pmSNA - STL

2 stops13h 21mMultiple Airlines

Sun 11/167:45 pmSTL - SNA

1 stop17h 31mMultiple Airlines

Deal found 9/18

$266

Mon 11/245:20 pmSNA - STL

1 stop5h 26mDelta

Tue 12/25:12 pmSTL - SNA

1 stop7h 08mDelta

Deal found 9/16

$354

Thu 10/309:42 amSNA - STL

1 stop7h 03mDelta

Sun 11/23:59 pmSTL - SNA

1 stop8h 29mDelta

Deal found 9/16

$375

Tue 10/141:44 pmSNA - STL

1 stop8h 40mDelta

Fri 10/173:59 pmSTL - SNA

1 stop8h 29mDelta

Deal found 9/16

$375

Last-minute flights from Santa Ana to St. Louis
Discover last-minute flight deals from Santa Ana to St. Louis. Data last updated September 18, 2025 and is based on user searches.

Fri 9/2611:52 amSNA - STL

1 stop19h 14mFrontier

Sun 9/282:38 pmSTL - SNA

1 stop23h 37mFrontier

Deal found 9/18

$213

Sat 9/2712:58 pmSNA - STL

1 stop18h 08mFrontier

Sun 9/282:38 pmSTL - SNA

1 stop23h 37mFrontier

Deal found 9/16

$156

Sun 9/2811:52 amSNA - STL

1 stop19h 14mFrontier

Sat 10/257:52 pmSTL - SNA

1 stop17h 24mFrontier

Deal found 9/18

$200

Tue 9/3012:58 pmSNA - STL

1 stop18h 08mFrontier

Wed 10/17:55 pmSTL - SNA

1 stop17h 12mFrontier

Deal found 9/17

$188

Tue 9/3012:58 pmSNA - STL

1 stop18h 08mMultiple Airlines

Wed 10/17:55 pmSTL - SNA

2 stops18h 10mMultiple Airlines

Deal found 9/17

$237

Fri 10/311:52 amSNA - STL

1 stop19h 14mMultiple Airlines

Tue 10/77:52 pmSTL - SNA

2 stops28h 11mMultiple Airlines

Deal found 9/18

$263

Mon 10/131:06 pmSNA - STL

1 stop5h 58mFrontier

Sat 10/187:52 pmSTL - SNA

1 stop17h 24mFrontier

Deal found 9/16

$225

Sat 10/182:20 pmSNA - STL

1 stop16h 47mFrontier

Mon 10/2012:38 pmSTL - SNA

1 stop8h 30mFrontier

Deal found 9/18

$198

Fri 10/242:35 pmSNA - STL

1 stop5h 39mFrontier

Mon 10/2712:38 pmSTL - SNA

1 stop8h 30mFrontier

Deal found 9/16

$144

Wed 10/292:20 pmSNA - STL

1 stop16h 47mFrontier

Sat 11/18:40 pmSTL - SNA

1 stop17h 36mFrontier

Deal found 9/18

$165

One-way flights from Santa Ana to St. Louis
Search for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 18, 2025.

Fri 10/242:35 pmSNA - STL

1 stop5h 39mFrontier

Deal found 9/15

$72

Mon 10/131:06 pmSNA - STL

1 stop5h 58mFrontier

Deal found 9/17

$84

Mon 10/201:06 pmSNA - STL

1 stop5h 58mFrontier

Deal found 9/18

$103

Wed 10/88:09 pmSNA - STL

2 stops10h 58mMultiple Airlines

Deal found 9/16

$109

Mon 11/105:46 pmSNA - STL

2 stops13h 21mMultiple Airlines

Deal found 9/18

$111

Fri 10/314:49 pmSNA - STL

2 stops20h 49mFrontier

Deal found 9/16

$116

Sun 9/2811:52 amSNA - STL

1 stop19h 14mFrontier

Deal found 9/18

$128

Fri 10/318:09 pmSNA - STL

2 stops35h 58mMultiple Airlines

Deal found 9/16

$133

Thu 11/1312:35 pmSNA - STL

1 stop9h 24mAlaska Airlines

Deal found 9/17

$152

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 10/29

2:20 pm-9:07 am

1 stop16h 47m

Lambert-St Louis

Sat 11/1

8:40 pm-12:16 pm

1 stop17h 36m

$165

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Sun 9/28

11:52 am-9:06 am

1 stop19h 14m

Lambert-St Louis

Sat 10/25

7:52 pm-11:16 am

1 stop17h 24m

$200

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 11/4

2:20 pm-9:07 am

1 stop16h 47m

Lambert-St Louis

Thu 11/6

7:45 pm-11:16 am

1 stop17h 31m

$224

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Fri 10/3

11:52 am-9:06 am

1 stop19h 14m

Lambert-St Louis

Tue 10/7

7:52 pm-10:03 pm

2 stops28h 11m

$263

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Sat 11/8

5:46 pm-9:07 am

2 stops13h 21m

Lambert-St Louis

Sun 11/16

7:45 pm-11:16 am

1 stop17h 31m

$266

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 10/22

11:48 am-8:23 pm

1 stop6h 35m

Lambert-St Louis

Mon 10/27

5:15 pm-10:28 pm

1 stop7h 13m

$333

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Mon 11/24

5:20 pm-12:46 am

1 stop5h 26m

Lambert-St Louis

Tue 12/2

5:12 pm-10:20 pm

1 stop7h 08m

$354

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Wed 10/29

12:45 pm-12:10 am

2 stops9h 25m

Lambert-St Louis

Sat 11/1

9:00 am-6:25 pm

2 stops11h 25m

$364

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Thu 10/30

9:42 am-6:45 pm

1 stop7h 03m

Lambert-St Louis

Sun 11/2

3:59 pm-10:28 pm

1 stop8h 29m

$375

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 10/14

1:44 pm-12:24 am

1 stop8h 40m

Lambert-St Louis

Fri 10/17

3:59 pm-10:28 pm

1 stop8h 29m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 19 results

Best time to book a flight from Santa Ana to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Ana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to St. Louis

What is the cheapest month to book a flight from Santa Ana to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Santa Ana to St. Louis (average of $311). Flying from Santa Ana to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to STL?

It’s optimal to fly from Santa Ana to St. Louis in the evening. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Santa Ana to St. Louis?

Travelers seeking maximum savings on their Santa Ana to St. Louis flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Santa Ana to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,242 reviews

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

8.0

Very good

7,961 reviews

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

8,926 reviews

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Frontier

5.8

Fair

3,171 reviews

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

How long is the flight from Santa Ana to St. Louis?
Airlines like Frontier fly from Santa Ana to St. Louis in about 16h 47m. The time it takes to get you to your destination can typically vary by up to . The distance between Santa Ana and St. Louis is about 1565 mi.
What are the cheapest airlines flying from Santa Ana to St. Louis round-trip?
Frontier, at $138, was found to be the cheapest airline from Santa Ana to St. Louis.Alternate airlines to your destination round-trip include Delta and Southwest. Frontier is priced at 69% lower than the current average price of a flight leaving 3 months from now.
Can I find deals for flights from Santa Ana to St. Louis that include hotel bookings?
Yes. In addition to deals on Santa Ana to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santa Ana to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to St. Louis.
Can I find deals for business class flights from Santa Ana to St. Louis?
Yes. Cheapflights offers flight deals from Santa Ana to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Santa Ana to St. Louis (average of $311). Flying from Santa Ana to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Edwardsville

O'Fallon

Fairview Heights

Maryland Heights

Collinsville

Eureka

Glencoe

St. Peters

Chesterfield

Alton

Farmington

Festus

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Santa Ana to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$138	Average$300	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$248	Average$490	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$311	Average$471	FlexibilityNo cancel fee	On-time63%
United Airlines	Cheapest$311	Average$451	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$326	Average$424	FlexibilityNo cancel fee	On-time71%

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$72+ Cheap flights from Santa Ana to St. Louis (SNA - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santa Ana to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Santa Ana to St. Louis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santa Ana to St. Louis

Cheapest flights from Santa Ana to St. LouisExplore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2025.

Explore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to St. Louis that are best for you.

Best time to book a flight from Santa Ana to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Ana with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to St. Louis

What is the cheapest month to book a flight from Santa Ana to St. Louis?

What is the cheapest time of day to fly from SNA to STL?

What is the cheapest day to fly from Santa Ana to St. Louis?

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Santa Ana to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Santa Ana to St. Louis?

What are the cheapest airlines flying from Santa Ana to St. Louis round-trip?

Can I find deals for flights from Santa Ana to St. Louis that include hotel bookings?

How can I find direct flights from Santa Ana to St. Louis?

Can I find deals for business class flights from Santa Ana to St. Louis?

What is the cheapest month to book a flight from Santa Ana to St. Louis?

Traveling to a place near St. Louis?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Santa Ana to St. Louis

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Cheapest flights from Santa Ana to St. Louis
Explore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2025.