$129+ Cheap flights from Santa Ana, CA to St. Louis (SNA - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — STL
Sep 6 — Sep 131
Round-trip
1 adult, Economy
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Find cheap flights from Santa Ana to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to St. Louis
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Cheapest flights from Santa Ana to St. LouisExplore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
Explore the most affordable flight options available from Santa Ana to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:07 am -
1 stop6h 08m
Sun 10/258:10 pm -
1 stop16h 02m
Deal found 8/3![Frontier logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:39 am -
1 stop7h 34m
Sun 9/67:58 pm -
1 stop14h 26m
Deal found 8/5![Frontier logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:35 pm -
2 stops24h 42m
Wed 9/308:10 pm -
1 stop16h 55m
Deal found 8/7![Frontier logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:30 am -
2 stops9h 45m
Fri 10/238:10 pm -
1 stop16h 02m
Deal found 8/7![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:07 am -
1 stop6h 08m
Thu 11/58:10 pm -
1 stop16h 01m
Deal found 8/6![Frontier logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:30 am -
2 stops9h 45m
Sun 10/188:10 pm -
1 stop16h 02m
Deal found 8/2![Multiple Airlines logo]()
$287
This Frontier deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:53 pm -
1 stop19h 57m
Wed 9/98:10 pm -
1 stop16h 55m
Deal found 8/7![Frontier logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:39 am -
1 stop7h 34m
Mon 8/316:45 pm -
1 stop22h 16m
Deal found 8/3![Multiple Airlines logo]()
$294
This CheapOair deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:35 pm -
1 stop16h 42m
Sat 9/268:10 pm -
1 stop16h 55m
Deal found 8/6![Frontier logo]()
$300
Best flights from Santa Ana to St. LouisDiscover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
Discover carefully curated flight deals from Santa Ana to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:30 am -
1 stop15h 47m
Sun 10/188:10 pm -
1 stop16h 02m
Deal found 8/2![Multiple Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:02 pm -
2 stops12h 38m
Wed 9/3011:21 am -
2 stops13h 09m
Deal found 8/2![Delta logo]()
$404
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:00 pm -
1 stop7h 40m
Tue 9/158:35 am -
1 stop8h 05m
Deal found 8/2![Southwest logo]()
$407
This Alaska Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:59 pm -
1 stop9h 00m
Mon 10/197:02 am -
1 stop10h 54m
Deal found 8/2![Alaska Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:30 am -
1 stop25h 47m
Wed 9/308:10 pm -
1 stop16h 55m
Deal found 8/2![Multiple Airlines logo]()
$352
This Alaska Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:59 pm -
1 stop9h 00m
Mon 11/27:00 am -
1 stop10h 41m
Deal found 8/5![Alaska Airlines logo]()
$429
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:00 pm -
2 stops7h 50m
Thu 10/16:00 am -
2 stops7h 55m
Deal found 8/7![Southwest logo]()
$439
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:20 am -
2 stops7h 25m
Fri 10/236:00 am -
2 stops7h 55m
Deal found 8/7![Southwest logo]()
$461
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:45 am -
2 stops7h 30m
Fri 9/42:20 pm -
2 stops8h 50m
Deal found 8/7![Southwest logo]()
$461
Last-minute flights from Santa Ana to St. LouisDiscover last-minute flight deals from Santa Ana to St. Louis. Data last updated August 7, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to St. Louis. Data last updated August 7, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:39 am -
1 stop7h 34m
Mon 8/316:45 pm -
1 stop22h 16m
Deal found 8/3![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:39 am -
1 stop7h 34m
Sun 8/305:27 pm -
2 stops22h 15m
Deal found 8/3![Frontier logo]()
$305
This Frontier deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:53 pm -
1 stop19h 57m
Wed 9/98:10 pm -
1 stop16h 55m
Deal found 8/7![Frontier logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:39 am -
1 stop7h 34m
Sun 9/67:58 pm -
1 stop14h 26m
Deal found 8/5![Frontier logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:39 am -
1 stop7h 34m
Thu 9/1010:20 am -
2 stops26h 45m
Deal found 8/5![Frontier logo]()
$309
This Expedia deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:50 am -
1 stop5h 27m
Mon 9/1412:17 pm -
1 stop6h 58m
Deal found 8/5![Frontier logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:35 pm -
2 stops24h 42m
Wed 9/308:10 pm -
1 stop16h 55m
Deal found 8/7![Frontier logo]()
$273
This CheapOair deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:35 pm -
1 stop16h 42m
Sat 9/268:10 pm -
1 stop16h 55m
Deal found 8/6![Frontier logo]()
$300
One-way flights from Santa Ana to St. LouisSearch for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
Search for one-way flight options from Santa Ana to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:39 am -
1 stop7h 34m
Deal found 8/2![Frontier logo]()
$129
This Expedia deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:46 pm -
1 stop27h 53m
Deal found 8/5![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:30 am -
2 stops9h 45m
Deal found 8/3![Multiple Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:30 am -
2 stops31h 47m
Deal found 8/6![Frontier logo]()
$173
This Priceline deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:09 am -
1 stop8h 04m
Deal found 8/7![Frontier logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:30 am -
3 stops48h 10m
Deal found 8/5![Multiple Airlines logo]()
$182
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:24 pm -
1 stop6h 35m
Deal found 8/5![American Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:30 am -
2 stops24h 05m
Deal found 8/3![Multiple Airlines logo]()
$196
Find flight deals from Santa Ana to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $269 (Kiwi.com) |
One-way from | $129 (Kiwi.com) |
Popular in | April |
Cheapest in | October |
Average price | $473 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Santa Ana to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Tue 10/13
7:30 am-1:17 am
1 stop15h 47m
Lambert-St Louis
Sun 10/18
8:10 pm-10:12 am
1 stop16h 02m
$313
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Wed 9/23
7:30 am-11:17 am
1 stop25h 47m
Lambert-St Louis
Wed 9/30
8:10 pm-11:05 am
1 stop16h 55m
$352
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Wed 9/23
6:02 pm-8:40 am
2 stops12h 38m
Lambert-St Louis
Wed 9/30
11:21 am-10:30 pm
2 stops13h 09m
$404
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Wed 9/9
1:00 pm-10:40 pm
1 stop7h 40m
Lambert-St Louis
Tue 9/15
8:35 am-2:40 pm
1 stop8h 05m
$407
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 10/15
12:59 pm-11:59 pm
1 stop9h 00m
Lambert-St Louis
Mon 10/19
7:02 am-3:56 pm
1 stop10h 54m
$429
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Thu 10/29
12:59 pm-11:59 pm
1 stop9h 00m
Lambert-St Louis
Mon 11/2
7:00 am-3:41 pm
1 stop10h 41m
$429
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Tue 9/29
1:00 pm-10:50 pm
2 stops7h 50m
Lambert-St Louis
Thu 10/1
6:00 am-11:55 am
2 stops7h 55m
$439
Quickest round-trip
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Wed 10/21
8:20 am-5:45 pm
2 stops7h 25m
Lambert-St Louis
Fri 10/23
6:00 am-11:55 am
2 stops7h 55m
$461
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Tue 9/1
8:45 am-6:15 pm
2 stops7h 30m
Lambert-St Louis
Fri 9/4
2:20 pm-9:10 pm
2 stops8h 50m
$461
Cheapest one-way
Santa AnaSt. Louis
SNA Santa Ana J. Wayne/Orange Cnty - STL Lambert-St Louis
SNASTL
Santa Ana J. Wayne/Orange Cnty
Fri 8/21
9:09 am-7:13 pm
1 stop8h 04m
$174
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to St. Louis in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Santa Ana with our price prediction graph.
SNA-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to St. Louis
Prices
More
What is the cheapest month to book a flight from Santa Ana, California to St. Louis?
Currently, October is the cheapest month in which you can book a flight from Santa Ana, California to St. Louis (average of $332). Flying from Santa Ana, California to St. Louis in April is currently the most expensive (average of $566). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Ana, California to St. Louis?
Airfare is below average for this route at the moment.
Santa Ana, California to St. Louis flights typically cost between $343 and $523 in October.The cheapest round-trip price found within the last 5 days was $269 on Frontier (Oct 23-Oct 25).
What’s the top layover airport for flights from Santa Ana, California to St. Louis?
Share of 1-stop round-trip flights from Santa Ana, California to St. Louis chosen by Cheapflights users in the past 12 months, using the same layover each way.
Las Vegas (LAS) – chosen by Cheapflights users on 83% of 1-stop itineraries from Santa Ana, California to St. Louis on Cheapflights.
What’s the cheapest layover airport for flights from Santa Ana, California to St. Louis?
Average round-trip fare for 1-stop flights from Santa Ana, California to St. Louis, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Phoenix (PHX) is the most affordable 1-stop option, with an average round-trip price of $541.
What’s the fastest layover option from Santa Ana, California to St. Louis?
Shortest average travel time for 1-stop one-way flights from Santa Ana, California to St. Louis, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Phoenix (PHX) have the shortest average one-way travel time for 1-stop routes: 5h 25m.
Which airport typically offers the quickest layover for flights from Santa Ana, California to St. Louis?
Average layover duration for 1-stop one-way flights from Santa Ana, California to St. Louis, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Phoenix (PHX) offer the fastest connection on this route, with an average layover time of 0h 50m.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated August 7, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Santa Ana to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Farmington
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Alternative routes for Santa Ana to St. Louis
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Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
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Santa Ana and St. Louis flights
Browse other Santa Ana and St. Louis flight options. Last updated on August 7, 2026.
Other flights from Santa Ana
Browse through other flights departing from Santa Ana. Flights are based on user searches made on Cheapflights and were last updated on August 7, 2026.
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 7, 2026.
Top 5 airlines flying from Santa Ana to St. Louis
Discover the top 5 airlines that operate flights from Santa Ana to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$129 | Average$211 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$276 | Average$408 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$311 | Average$436 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$316 | Average$519 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$317 | Average$523 | FlexibilityNo cancel fee | On-time71% |