$70+ Cheap flights from Mississippi to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — STL
May 30 — Jun 61
Round-trip
1 adult, Economy
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Find cheap flights from Mississippi to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to St. Louis
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Cheapest flights from Mississippi to St. LouisExplore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.
Explore the most affordable flight options available from Mississippi to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.
This CheapOair deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1011:59 am
MEM
- STL
1 stop4h 55m
Frontier
Thu 5/148:08 pm
STL
- MEM
1 stop23h 01m
Frontier
Deal found 4/25![Frontier logo]()
$212
This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:51 pm
MEM
- STL
1 stop23h 32m
Frontier
Sun 8/28:08 pm
STL
- MEM
1 stop22h 58m
Frontier
Deal found 4/29![Frontier logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:59 am
MEM
- STL
1 stop5h 34m
Multiple Airlines
Wed 6/35:27 pm
STL
- MEM
2 stops14h 18m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:59 am
MEM
- STL
1 stop20h 56m
Frontier
Wed 6/35:27 pm
STL
- MEM
1 stop17h 32m
Frontier
Deal found 4/26![Frontier logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:59 am
MEM
- STL
1 stop20h 56m
Multiple Airlines
Wed 5/205:27 pm
STL
- MEM
2 stops24h 22m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$272
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:15 am
JAN
- STL
1 stop5h 23m
Delta
Wed 8/127:05 pm
STL
- JAN
1 stop4h 14m
Delta
Deal found 4/27![Delta logo]()
$275
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:39 pm
GPT
- STL
1 stop6h 51m
American Airlines
Sat 5/165:20 am
STL
- GPT
1 stop5h 13m
American Airlines
Deal found 4/27![American Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:54 pm
MEM
- STL
2 stops21h 39m
Frontier
Wed 6/35:27 pm
STL
- MEM
1 stop17h 32m
Frontier
Deal found 4/27![Frontier logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:54 pm
MEM
- STL
1 stop23h 29m
Multiple Airlines
Wed 5/205:27 pm
STL
- MEM
2 stops24h 22m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:59 am
MEM
- STL
1 stop20h 56m
Multiple Airlines
Tue 5/196:33 pm
STL
- MEM
2 stops45h 59m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:59 am
MEM
- STL
1 stop20h 56m
Frontier
Wed 5/205:27 pm
STL
- MEM
1 stop23h 12m
Frontier
Deal found 4/26![Frontier logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:59 am
MEM
- STL
1 stop20h 56m
Multiple Airlines
Mon 5/184:19 pm
STL
- MEM
1 stop24h 13m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$311
Best flights from Mississippi to St. LouisDiscover carefully curated flight deals from Mississippi to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 30, 2026.
Discover carefully curated flight deals from Mississippi to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 30, 2026.
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:39 pm
GPT
- STL
1 stop6h 51m
American Airlines
Sat 5/165:20 am
STL
- GPT
1 stop5h 13m
American Airlines
Deal found 4/27![American Airlines logo]()
$285
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:02 pm
GPT
- STL
1 stop5h 57m
Delta
Sun 5/249:13 am
STL
- GPT
1 stop4h 51m
Delta
Deal found 4/26![Delta logo]()
$285
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:00 am
GPT
- STL
1 stop7h 16m
United Airlines
Thu 5/288:35 am
STL
- GPT
1 stop7h 36m
United Airlines
Deal found 4/25![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:20 pm
JAN
- STL
1 stop5h 10m
Southwest
Mon 8/32:25 pm
STL
- JAN
1 stop5h 20m
Southwest
Deal found 4/27![Southwest logo]()
$347
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:59 am
MEM
- STL
1 stop4h 55m
Frontier
Sun 5/178:08 pm
STL
- MEM
1 stop23h 01m
Frontier
Deal found 4/28![Frontier logo]()
$451
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:04 pm
BTR
- STL
1 stop4h 55m
Delta
Sun 6/77:08 am
STL
- BTR
1 stop5h 39m
Delta
Deal found 4/26![Delta logo]()
$317
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/212:19 pm
BTR
- STL
2 stops9h 37m
American Airlines
Wed 7/225:29 am
STL
- BTR
1 stop5h 29m
American Airlines
Deal found 4/25![American Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:57 am
GPT
- STL
1 stop5h 04m
United Airlines
Wed 10/288:50 am
STL
- GPT
1 stop4h 36m
United Airlines
Deal found 4/27![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:08 pm
BTR
- STL
1 stop4h 48m
Delta
Sun 6/217:08 am
STL
- BTR
1 stop5h 39m
Delta
Deal found 4/28![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:25 am
MEM
- STL
1 stop4h 30m
Southwest
Sat 5/232:05 pm
STL
- MEM
1 stop5h 55m
Southwest
Deal found 4/29![Southwest logo]()
$365
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:00 pm
BTR
- STL
1 stop6h 18m
Delta
Mon 7/66:00 am
STL
- BTR
1 stop6h 47m
Delta
Deal found 4/29![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:20 pm
JAN
- STL
1 stop5h 05m
Southwest
Mon 6/225:05 am
STL
- JAN
2 stops5h 40m
Southwest
Deal found 4/28![Southwest logo]()
$369
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:01 pm
BTR
- STL
1 stop7h 29m
American Airlines
Mon 5/186:11 pm
STL
- BTR
1 stop4h 40m
American Airlines
Deal found 4/29![American Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:00 am
JAN
- STL
1 stop5h 08m
United Airlines
Wed 8/126:14 am
STL
- JAN
1 stop4h 59m
United Airlines
Deal found 4/27![United Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:00 pm
BTR
- STL
1 stop4h 37m
Delta
Sun 9/209:00 am
STL
- BTR
1 stop5h 47m
Delta
Deal found 4/25![Delta logo]()
$317
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:06 pm
BTR
- STL
1 stop4h 47m
Delta
Wed 7/227:08 am
STL
- BTR
1 stop5h 39m
Delta
Deal found 4/27![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:30 am
JAN
- STL
1 stop4h 05m
Southwest
Sun 6/73:05 pm
STL
- JAN
2 stops6h 55m
Southwest
Deal found 4/26![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:40 am
PIB
- STL
1 stop7h 02m
United Airlines
Mon 8/38:35 am
STL
- PIB
1 stop5h 45m
United Airlines
Deal found 4/27![United Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
MEM
- STL
1 stop5h 20m
Southwest
Fri 8/1410:55 am
STL
- MEM
1 stop5h 15m
Southwest
Deal found 4/26![Southwest logo]()
$394
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:10 am
MOB
- STL
2 stops8h 53m
American Airlines
Sun 5/175:20 am
STL
- MOB
1 stop4h 46m
American Airlines
Deal found 4/28![American Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/24:07 pm
MEM
- STL
1 stop7h 29m
United Airlines
Wed 6/36:00 am
STL
- MEM
1 stop5h 05m
United Airlines
Deal found 4/28![United Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:08 pm
BTR
- STL
1 stop4h 48m
Delta
Sun 7/56:00 am
STL
- BTR
1 stop6h 47m
Delta
Deal found 4/29![Delta logo]()
$338
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:10 pm
BTR
- STL
2 stops9h 06m
United Airlines
Fri 6/56:30 pm
STL
- BTR
1 stop4h 16m
United Airlines
Deal found 4/27![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:18 am
MOB
- STL
1 stop6h 04m
Delta
Sat 5/166:00 am
STL
- MOB
1 stop6h 05m
Delta
Deal found 4/27![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:20 pm
MEM
- STL
2 stops6h 35m
Southwest
Sun 5/249:00 am
STL
- MEM
2 stops8h 25m
Southwest
Deal found 4/26![Southwest logo]()
$418
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:29 pm
MOB
- STL
2 stops7h 25m
American Airlines
Sun 5/315:25 am
STL
- MOB
1 stop6h 00m
American Airlines
Deal found 4/28![American Airlines logo]()
$466
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:00 pm
GPT
- STL
2 stops10h 30m
United Airlines
Sat 8/223:02 pm
STL
- GPT
1 stop4h 40m
United Airlines
Deal found 4/28![United Airlines logo]()
$411
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:23 pm
JAN
- STL
1 stop4h 36m
Delta
Mon 5/256:00 am
STL
- JAN
1 stop4h 04m
Delta
Deal found 4/27![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:10 am
MEM
- STL
2 stops6h 25m
Southwest
Fri 6/124:00 pm
STL
- MEM
1 stop6h 25m
Southwest
Deal found 4/25![Southwest logo]()
$456
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:23 pm
MEM
- STL
1 stop7h 22m
United Airlines
Wed 6/36:00 am
STL
- MEM
1 stop5h 05m
United Airlines
Deal found 4/26![United Airlines logo]()
$421
Last-minute flights from Mississippi to St. LouisDiscover last-minute flight deals from Mississippi to St. Louis. Data last updated April 30, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to St. Louis. Data last updated April 30, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:37 pm
MEM
- STL
1 stop6h 44m
Multiple Airlines
Wed 5/205:27 pm
STL
- MEM
2 stops24h 22m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$325
This CheapOair deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1011:59 am
MEM
- STL
1 stop4h 55m
Frontier
Thu 5/148:08 pm
STL
- MEM
1 stop23h 01m
Frontier
Deal found 4/25![Frontier logo]()
$212
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:39 pm
GPT
- STL
1 stop6h 51m
American Airlines
Sat 5/165:20 am
STL
- GPT
1 stop5h 13m
American Airlines
Deal found 4/27![American Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:54 pm
MEM
- STL
1 stop23h 29m
Multiple Airlines
Wed 5/205:27 pm
STL
- MEM
2 stops24h 22m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:59 am
MEM
- STL
1 stop20h 56m
Multiple Airlines
Wed 5/205:27 pm
STL
- MEM
2 stops24h 22m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:59 am
MEM
- STL
1 stop20h 56m
Multiple Airlines
Tue 5/196:33 pm
STL
- MEM
2 stops45h 59m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:59 am
MEM
- STL
1 stop20h 56m
Frontier
Wed 5/205:27 pm
STL
- MEM
1 stop23h 12m
Frontier
Deal found 4/26![Frontier logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:59 am
MEM
- STL
1 stop20h 56m
Multiple Airlines
Mon 5/184:19 pm
STL
- MEM
1 stop24h 13m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:02 pm
GPT
- STL
1 stop5h 57m
Delta
Sun 5/245:20 pm
STL
- GPT
1 stop4h 31m
Delta
Deal found 4/27![Delta logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:37 pm
MEM
- STL
2 stops25h 46m
Multiple Airlines
Sat 5/305:27 pm
STL
- MEM
1 stop17h 32m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:36 pm
BTR
- STL
1 stop4h 23m
American Airlines
Sun 5/315:25 am
STL
- BTR
1 stop5h 35m
American Airlines
Deal found 4/26![American Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:54 pm
MEM
- STL
2 stops21h 39m
Frontier
Wed 6/35:27 pm
STL
- MEM
1 stop17h 32m
Frontier
Deal found 4/27![Frontier logo]()
$288
One-way flights from Mississippi to St. LouisSearch for one-way flight options from Mississippi to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 30, 2026.
Search for one-way flight options from Mississippi to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 30, 2026.
This Priceline deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2411:59 am
MEM
- STL
1 stop5h 34m
Frontier
Deal found 4/26![Frontier logo]()
$70
This CheapOair deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:51 pm
MEM
- STL
1 stop24h 32m
Frontier
Deal found 4/26![Frontier logo]()
$102
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:51 am
MEM
- STL
1 stop5h 46m
Frontier
Deal found 4/29![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:50 pm
GPT
- STL
1 stop28h 19m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$125
This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:59 pm
MEM
- STL
1 stop23h 24m
Frontier
Deal found 4/29![Frontier logo]()
$127
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:56 pm
GPT
- STL
1 stop6h 00m
Delta
Deal found 4/27![Delta logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/191:45 pm
MEM
- STL
2 stops28h 49m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$150
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am
BTR
- STL
1 stop6h 53m
Delta
Deal found 4/28![Delta logo]()
$159
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:36 pm
BTR
- STL
1 stop4h 23m
American Airlines
Deal found 4/27![American Airlines logo]()
$163
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:00 pm
JAN
- STL
1 stop4h 56m
Delta
Deal found 4/26![Delta logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:37 pm
MEM
- STL
2 stops15h 18m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:50 pm
GPT
- STL
1 stop28h 31m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$203
Find flight deals from Mississippi to St. Louis
Keep the following information in mind while searching for Mississippi to St. Louis flight deals. Data was last updated April 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $212 (CheapOair) |
One-way from | $70 (Frontier) |
Popular in | May |
Cheapest in | February |
Average price | $326 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Mississippi to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GulfportSt. Louis
GPT - STL
GPTSTL
Gulfport Biloxi Regional
Tue 5/12
12:39 pm-7:30 pm
1 stop6h 51m
Lambert-St Louis
Sat 5/16
5:20 am-10:33 am
1 stop5h 13m
$285
GulfportSt. Louis
GPT - STL
GPTSTL
Gulfport Biloxi Regional
Fri 5/22
6:02 pm-11:59 pm
1 stop5h 57m
Lambert-St Louis
Sun 5/24
9:13 am-2:04 pm
1 stop4h 51m
$285
Baton RougeSt. Louis
BTR - STL
BTRSTL
Baton Rouge Ryan
Fri 6/5
7:04 pm-11:59 pm
1 stop4h 55m
Lambert-St Louis
Sun 6/7
7:08 am-12:47 pm
1 stop5h 39m
$317
Baton RougeSt. Louis
BTR - STL
BTRSTL
Baton Rouge Ryan
Thu 6/18
7:08 pm-11:56 pm
1 stop4h 48m
Lambert-St Louis
Sun 6/21
7:08 am-12:47 pm
1 stop5h 39m
$317
Baton RougeSt. Louis
BTR - STL
BTRSTL
Baton Rouge Ryan
Thu 7/2
4:00 pm-10:18 pm
1 stop6h 18m
Lambert-St Louis
Mon 7/6
6:00 am-12:47 pm
1 stop6h 47m
$317
Baton RougeSt. Louis
BTR - STL
BTRSTL
Baton Rouge Ryan
Thu 9/17
7:00 pm-11:37 pm
1 stop4h 37m
Lambert-St Louis
Sun 9/20
9:00 am-2:47 pm
1 stop5h 47m
$317
Baton RougeSt. Louis
BTR - STL
BTRSTL
Baton Rouge Ryan
Tue 7/21
7:06 pm-11:53 pm
1 stop4h 47m
Lambert-St Louis
Wed 7/22
7:08 am-12:47 pm
1 stop5h 39m
$317
Baton RougeSt. Louis
BTR - STL
BTRSTL
Baton Rouge Ryan
Tue 7/21
2:19 pm-11:56 pm
2 stops9h 37m
Lambert-St Louis
Wed 7/22
5:29 am-10:58 am
1 stop5h 29m
$322
GulfportSt. Louis
GPT - STL
GPTSTL
Gulfport Biloxi Regional
Thu 5/21
7:00 am-2:16 pm
1 stop7h 16m
Lambert-St Louis
Thu 5/28
8:35 am-4:11 pm
1 stop7h 36m
$334
Baton RougeSt. Louis
BTR - STL
BTRSTL
Baton Rouge Ryan
Thu 7/2
7:08 pm-11:56 pm
1 stop4h 48m
Lambert-St Louis
Sun 7/5
6:00 am-12:47 pm
1 stop6h 47m
$338
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Mississippi to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mississippi with our price prediction graph.
MEM-STL
JAN-STL
GPT-STL
BTR-STL
PIB-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to St. Louis
USMS-STL
MEM-STL
JAN-STL
GPT-STL
BTR-STL
What is the cheapest month to book a flight from Mississippi to St. Louis?
Currently, March is the cheapest month in which you can book a flight from Mississippi to St. Louis (average of $224). Flying from Mississippi to St. Louis in December is currently the most expensive (average of $431). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Mississippi to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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St. Louis flight routes
Top destinations
Alternative routes for Mississippi to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mississippi to St. Louis by cabin class
Find flights from Mississippi to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mississippi and St. Louis flights
Browse other Mississippi and St. Louis flight options. Last updated on April 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 30, 2026.
Mississippi to St. Louis flights
Consider these flights traveling from Mississippi to St. Louis.
Top 2 airlines flying from Mississippi to St. Louis
Discover the top 2 airlines that operate flights from Mississippi to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$424 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$468 | FlexibilityNo cancel fee | On-timeN/A |