How long is the flight from Maine to St. Louis?

United Airlines, American Airlines, and Southwest can get you from Maine to St. Louis in just under 3h 15m. Your travel time can differ by up to 2h 53m. The distance from Maine to St. Louis is about 1043 mi. This flight may include one or multiple stops.

What are the cheapest airlines to fly from Maine to St. Louis one-way?

One-way options have recently been found by users for as low as $95 on Spirit Airlines. Other airlines that offer cheap prices include Frontier from $146 and American Airlines from $149 one-way.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular routes from Maine to St. Louis?

Most travelers choose Boston Logan Intl - Lambert-St Louis, Portland - Lambert-St Louis or Bangor - Lambert-St Louis when deciding on the best route from Maine to St. Louis.

What are the most popular airlines that fly from Maine to St. Louis?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Maine to St. Louis.

What airport do you fly into for flights to St. Louis from Maine?

If you book a flight to St. Louis from Maine, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.

Can I find deals for flights from Maine to St. Louis that include hotel bookings?

Yes. In addition to deals on Maine to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Maine to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to St. Louis.

Can I find deals for business class flights from Maine to St. Louis?

Yes. Cheapflights offers flight deals from Maine to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$87+ Flights from Maine to St. Louis

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Maine to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Maine to St. Louis

Round-trip from	$273 (Kiwi.com)
One-way from	$87 (Kiwi.com)
Popular in	December
Cheapest in	February
Average price	$340

From Maine to Lambert-St Louis

Search Deals

One-way flight from Maine to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($48 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

Search Deals

Find flight deals from Maine to St. Louis

Cheapest flights from Maine to St. Louis
Explore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Fri 10/178:24 pmBOS - STL

1 stop22h 46mMultiple Airlines

Mon 10/208:21 pmSTL - BOS

2 stops15h 59mMultiple Airlines

Deal found 9/15

$273

Thu 10/99:50 amBOS - STL

1 stop25h 47mMultiple Airlines

Sat 10/117:15 pmSTL - BOS

1 stop15h 11mMultiple Airlines

Deal found 9/14

$274

Fri 10/248:24 pmBOS - STL

1 stop22h 46mSpirit Airlines

Sun 10/2610:57 amSTL - BOS

1 stop12h 02mSpirit Airlines

Deal found 9/14

$275

Sat 10/188:00 amBOS - STL

1 stop9h 04mAmerican Airlines

Mon 10/209:35 amSTL - BOS

Nonstop2h 37mAmerican Airlines

Deal found 9/14

$276

Sat 11/112:31 pmBOS - STL

1 stop23h 31mMultiple Airlines

Tue 11/47:45 pmSTL - BOS

2 stops25h 23mMultiple Airlines

Deal found 9/15

$278

Fri 10/312:59 pmBOS - STL

2 stops21h 07mMultiple Airlines

Sun 10/510:57 amSTL - BOS

1 stop23h 29mMultiple Airlines

Deal found 9/14

$279

Tue 12/26:00 amBOS - STL

1 stop5h 18mAmerican Airlines

Sat 12/61:59 pmSTL - BOS

1 stop9h 00mAmerican Airlines

Deal found 9/14

$280

Sat 10/43:00 pmBOS - STL

1 stop20h 02mMultiple Airlines

Mon 10/67:55 pmSTL - BOS

2 stops16h 25mMultiple Airlines

Deal found 9/14

$284

Tue 10/282:15 pmBOS - STL

2 stops19h 52mMultiple Airlines

Thu 10/3010:57 amSTL - BOS

1 stop12h 02mMultiple Airlines

Deal found 9/15

$285

Tue 11/186:48 amBOS - STL

1 stop9h 14mAmerican Airlines

Sat 11/224:32 pmSTL - BOS

1 stop5h 12mAmerican Airlines

Deal found 9/14

$286

Sat 10/186:45 amBGR - STL

1 stop6h 02mUnited Airlines

Sat 10/2512:25 pmSTL - BGR

1 stop8h 15mUnited Airlines

Deal found 9/16

$286

Sun 12/79:00 amBOS - STL

1 stop8h 59mAmerican Airlines

Wed 12/102:48 pmSTL - BOS

Nonstop2h 38mAmerican Airlines

Deal found 9/14

$287

Best flights from Maine to St. Louis
Discover carefully curated flight deals from Maine to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2025.

Sat 10/186:45 amBGR - STL

1 stop6h 02mUnited Airlines

Sat 10/2512:25 pmSTL - BGR

1 stop8h 15mUnited Airlines

Deal found 9/16

$286

Fri 11/73:52 pmBGR - STL

1 stop6h 08mAmerican Airlines

Mon 11/105:06 pmSTL - BGR

1 stop5h 07mAmerican Airlines

Deal found 9/16

$301

Sat 12/67:25 amBOS - STL

Nonstop3h 15mSouthwest

Wed 12/106:10 pmSTL - BOS

Nonstop2h 30mSouthwest

Deal found 9/14

$333

Wed 10/294:48 pmPWM - STL

2 stops7h 18mDelta

Sun 11/25:00 amSTL - PWM

1 stop5h 32mDelta

Deal found 9/14

$357

Tue 10/79:53 amBOS - STL

1 stop5h 34mUnited Airlines

Wed 10/85:00 amSTL - BOS

1 stop5h 02mUnited Airlines

Deal found 9/15

$297

Fri 11/73:52 pmBGR - STL

1 stop6h 08mAmerican Airlines

Tue 11/116:14 pmSTL - BGR

1 stop4h 44mAmerican Airlines

Deal found 9/16

$301

Sat 11/15:35 amBOS - STL

Nonstop3h 00mSouthwest

Tue 11/46:10 pmSTL - BOS

Nonstop2h 30mSouthwest

Deal found 9/15

$333

Tue 10/216:14 amPWM - STL

1 stop5h 35mUnited Airlines

Fri 10/246:30 amSTL - PWM

1 stop7h 03mUnited Airlines

Deal found 9/14

$322

Sat 11/86:00 amBGR - STL

1 stop6h 38mDelta

Tue 11/115:14 pmSTL - BGR

1 stop5h 14mDelta

Deal found 9/15

$359

Sat 11/83:52 pmBGR - STL

1 stop6h 08mAmerican Airlines

Tue 11/116:14 pmSTL - BGR

1 stop4h 44mAmerican Airlines

Deal found 9/13

$339

Tue 12/25:15 pmBOS - STL

Nonstop3h 15mSouthwest

Mon 12/812:45 pmSTL - BOS

2 stops7h 20mSouthwest

Deal found 9/14

$348

Tue 10/2112:10 pmBOS - STL

1 stop4h 57mUnited Airlines

Fri 10/2412:25 pmSTL - BOS

1 stop6h 06mUnited Airlines

Deal found 9/14

$329

Tue 10/215:42 amPWM - STL

2 stops11h 13mDelta

Fri 10/244:10 pmSTL - PWM

1 stop6h 55mDelta

Deal found 9/14

$368

Fri 11/73:52 pmBGR - STL

1 stop6h 08mAmerican Airlines

Sun 11/96:00 amSTL - BGR

1 stop5h 11mAmerican Airlines

Deal found 9/16

$343

Sat 12/612:50 pmBOS - STL

2 stops9h 00mSouthwest

Tue 12/91:15 pmSTL - BOS

2 stops8h 00mSouthwest

Deal found 9/14

$363

Thu 2/266:00 amPWM - STL

1 stop6h 55mDelta

Sun 3/16:45 amSTL - PWM

1 stop4h 12mDelta

Deal found 9/14

$397

Thu 10/911:02 amBOS - STL

1 stop9h 40mUnited Airlines

Mon 10/139:20 amSTL - BOS

1 stop11h 25mUnited Airlines

Deal found 9/14

$363

Tue 12/29:05 amBOS - STL

2 stops8h 15mSouthwest

Sat 12/66:25 amSTL - BOS

2 stops7h 20mSouthwest

Deal found 9/14

$363

Thu 10/166:00 amPWM - STL

1 stop4h 56mAmerican Airlines

Sun 10/196:00 amSTL - PWM

1 stop6h 18mAmerican Airlines

Deal found 9/14

$367

Wed 12/35:45 amBOS - STL

2 stops7h 50mSouthwest

Sat 12/66:25 amSTL - BOS

2 stops7h 20mSouthwest

Deal found 9/14

$363

Tue 9/306:40 amBGR - STL

1 stop5h 08mUnited Airlines

Sat 10/43:23 pmSTL - BGR

1 stop5h 17mUnited Airlines

Deal found 9/15

$369

Wed 10/85:42 amPWM - STL

2 stops10h 01mDelta

Sun 10/126:40 amSTL - PWM

1 stop4h 20mDelta

Deal found 9/14

$412

Sat 10/116:00 amPWM - STL

1 stop4h 41mAmerican Airlines

Sat 10/114:25 pmSTL - PWM

1 stop5h 37mAmerican Airlines

Deal found 9/14

$379

Tue 10/215:30 amBOS - STL

1 stop7h 15mSouthwest

Fri 10/248:10 pmSTL - BOS

Nonstop2h 30mSouthwest

Deal found 9/14

$370

Tue 10/79:53 amBOS - STL

1 stop5h 34mUnited Airlines

Fri 10/1012:25 pmSTL - BOS

1 stop6h 06mUnited Airlines

Deal found 9/14

$379

Sun 12/71:30 pmBOS - STL

Nonstop3h 05mSouthwest

Tue 12/96:10 pmSTL - BOS

Nonstop2h 30mSouthwest

Deal found 9/14

$379

Thu 10/166:14 amPWM - STL

1 stop5h 35mUnited Airlines

Sat 10/183:23 pmSTL - PWM

2 stops7h 36mUnited Airlines

Deal found 9/16

$412

Fri 10/176:14 amPWM - STL

1 stop5h 35mUnited Airlines

Mon 10/203:23 pmSTL - PWM

1 stop5h 21mUnited Airlines

Deal found 9/15

$417

Last-minute flights from Maine to St. Louis
Discover last-minute flight deals from Maine to St. Louis. Data last updated September 16, 2025 and is based on user searches.

Wed 10/13:00 pmBOS - STL

1 stop19h 40mMultiple Airlines

Fri 10/39:32 pmSTL - BOS

1 stop15h 16mMultiple Airlines

Deal found 9/15

$290

Fri 10/312:59 pmBOS - STL

2 stops21h 07mMultiple Airlines

Sun 10/510:57 amSTL - BOS

1 stop23h 29mMultiple Airlines

Deal found 9/14

$279

Sat 10/43:00 pmBOS - STL

1 stop20h 02mMultiple Airlines

Mon 10/67:55 pmSTL - BOS

2 stops16h 25mMultiple Airlines

Deal found 9/14

$284

Thu 10/99:50 amBOS - STL

1 stop25h 47mMultiple Airlines

Sat 10/117:15 pmSTL - BOS

1 stop15h 11mMultiple Airlines

Deal found 9/14

$274

Thu 10/166:00 amPWM - STL

1 stop4h 56mAmerican Airlines

Sat 10/188:42 amSTL - PWM

1 stop5h 14mAmerican Airlines

Deal found 9/16

$327

Fri 10/178:24 pmBOS - STL

1 stop22h 46mMultiple Airlines

Mon 10/208:21 pmSTL - BOS

2 stops15h 59mMultiple Airlines

Deal found 9/15

$273

Sat 10/188:00 amBOS - STL

1 stop9h 04mAmerican Airlines

Mon 10/209:35 amSTL - BOS

Nonstop2h 37mAmerican Airlines

Deal found 9/14

$276

Sat 10/186:45 amBGR - STL

1 stop6h 02mUnited Airlines

Sat 10/2512:25 pmSTL - BGR

1 stop8h 15mUnited Airlines

Deal found 9/16

$286

Tue 10/216:14 amPWM - STL

1 stop5h 35mUnited Airlines

Fri 10/246:30 amSTL - PWM

1 stop7h 03mUnited Airlines

Deal found 9/14

$322

Fri 10/248:24 pmBOS - STL

1 stop22h 46mSpirit Airlines

Sun 10/2610:57 amSTL - BOS

1 stop12h 02mSpirit Airlines

Deal found 9/14

$275

Fri 10/248:24 pmBOS - STL

1 stop22h 46mMultiple Airlines

Mon 10/276:05 pmSTL - BOS

1 stop18h 15mMultiple Airlines

Deal found 9/15

$287

Tue 10/282:15 pmBOS - STL

2 stops19h 52mMultiple Airlines

Thu 10/3010:57 amSTL - BOS

1 stop12h 02mMultiple Airlines

Deal found 9/15

$285

One-way flights from Maine to St. Louis
Search for one-way flight options from Maine to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 16, 2025.

Wed 10/156:16 amBOS - STL

1 stop28h 46mSpirit Airlines

Deal found 9/15

$87

Sat 1/245:45 amBOS - STL

1 stop9h 08mSpirit Airlines

Deal found 9/15

$95

Wed 10/156:16 amBOS - STL

2 stops28h 06mMultiple Airlines

Deal found 9/15

$99

Wed 1/215:45 amBOS - STL

1 stop30h 16mSpirit Airlines

Deal found 9/14

$101

Wed 10/226:16 amBOS - STL

1 stop28h 46mSpirit Airlines

Deal found 9/13

$102

Tue 11/46:48 amBOS - STL

1 stop9h 14mAmerican Airlines

Deal found 9/14

$107

Tue 10/73:00 pmBOS - STL

2 stops43h 22mMultiple Airlines

Deal found 9/15

$109

Fri 10/178:24 pmBOS - STL

1 stop22h 46mSpirit Airlines

Deal found 9/13

$113

Tue 10/76:00 amPWM - STL

1 stop5h 24mAmerican Airlines

Deal found 9/14

$149

Tue 12/25:30 amPWM - STL

2 stops9h 20mSouthwest

Deal found 9/14

$154

Thu 10/163:28 pmPWM - STL

1 stop5h 58mAmerican Airlines

Deal found 9/14

$164

Tue 12/25:37 pmPWM - STL

1 stop7h 19mAmerican Airlines

Deal found 9/14

$169

Fly from

Fly to

Route

Depart

Return

Price

BangorSt. Louis

BGR - STL

BGRSTL

Bangor

Sat 10/18

6:45 am-11:47 am

1 stop6h 02m

Lambert-St Louis

Sat 10/25

12:25 pm-9:40 pm

1 stop8h 15m

$286

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Tue 10/7

9:53 am-2:27 pm

1 stop5h 34m

Lambert-St Louis

Wed 10/8

5:00 am-11:02 am

1 stop5h 02m

$297

BangorSt. Louis

BGR - STL

BGRSTL

Bangor

Fri 11/7

3:52 pm-9:00 pm

1 stop6h 08m

Lambert-St Louis

Mon 11/10

5:06 pm-11:13 pm

1 stop5h 07m

$301

BangorSt. Louis

BGR - STL

BGRSTL

Bangor

Fri 11/7

3:52 pm-9:00 pm

1 stop6h 08m

Lambert-St Louis

Tue 11/11

6:14 pm-11:58 pm

1 stop4h 44m

$301

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Tue 10/21

6:14 am-10:49 am

1 stop5h 35m

Lambert-St Louis

Fri 10/24

6:30 am-2:33 pm

1 stop7h 03m

$322

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Tue 10/21

12:10 pm-4:07 pm

1 stop4h 57m

Lambert-St Louis

Fri 10/24

12:25 pm-7:31 pm

1 stop6h 06m

$329

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Sat 12/6

7:25 am-9:40 am

Nonstop3h 15m

Lambert-St Louis

Wed 12/10

6:10 pm-9:40 pm

Nonstop2h 30m

$333

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Sat 11/1

5:35 am-7:35 am

Nonstop3h 00m

Lambert-St Louis

Tue 11/4

6:10 pm-9:40 pm

Nonstop2h 30m

$333

BangorSt. Louis

BGR - STL

BGRSTL

Bangor

Sat 11/8

3:52 pm-9:00 pm

1 stop6h 08m

Lambert-St Louis

Tue 11/11

6:14 pm-11:58 pm

1 stop4h 44m

$339

BangorSt. Louis

BGR - STL

BGRSTL

Bangor

Fri 11/7

3:52 pm-9:00 pm

1 stop6h 08m

Lambert-St Louis

Sun 11/9

6:00 am-12:11 pm

1 stop5h 11m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 51 results

...

Best time to book a flight from Maine to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Maine with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to St. Louis

What is the cheapest month to book a flight from Maine to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Maine to St. Louis (average of $311). Flying from Maine to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ME to STL?

When flying from Maine to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

What airport do you fly into for flights to St. Louis from Maine?
If you book a flight to St. Louis from Maine, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.
How long is the flight from Maine to St. Louis?
United Airlines, American Airlines, and Southwest can get you from Maine to St. Louis in just under 3h 15m. Your travel time can differ by up to 2h 53m. The distance from Maine to St. Louis is about 1043 mi. This flight may include one or multiple stops.
What are the cheapest airlines to fly from Maine to St. Louis one-way?
One-way options have recently been found by users for as low as $95 on Spirit Airlines. Other airlines that offer cheap prices include Frontier from $146 and American Airlines from $149 one-way.
What are the most popular routes from Maine to St. Louis?
Most travelers choose Boston Logan Intl - Lambert-St Louis, Portland - Lambert-St Louis or Bangor - Lambert-St Louis when deciding on the best route from Maine to St. Louis.
Can I find deals for flights from Maine to St. Louis that include hotel bookings?
Yes. In addition to deals on Maine to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Maine to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to St. Louis.
Can I find deals for business class flights from Maine to St. Louis?
Yes. Cheapflights offers flight deals from Maine to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Maine to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Maine to St. Louis (average of $311). Flying from Maine to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Edwardsville

O'Fallon

Fairview Heights

Maryland Heights

Collinsville

Eureka

Glencoe

St. Peters

Chesterfield

Alton

Farmington

Festus

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Maine to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$236	Average$370	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$241	Average$423	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$341	Average$466	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$371	Average$417	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$87+ Cheap flights from Maine to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Maine to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Maine to St. Louis

Keep the following information in mind while searching for Maine to St. Louis flight deals. Data was last updated September 16, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Maine to St. Louis

Cheapest flights from Maine to St. LouisExplore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Explore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Maine to St. Louis that are best for you.

Best time to book a flight from Maine to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Maine with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Maine to St. Louis

What is the cheapest month to book a flight from Maine to St. Louis?

What is the cheapest time of day to fly from ME to STL?

Find hourly flight availability from Maine to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Related info for your journey

Find useful and relevant information for your journey from Maine to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Maine?

How long is the flight from Maine to St. Louis?

What are the cheapest airlines to fly from Maine to St. Louis one-way?

What are the most popular routes from Maine to St. Louis?

Can I find deals for flights from Maine to St. Louis that include hotel bookings?

How can I find direct flights from Maine to St. Louis?

Can I find deals for business class flights from Maine to St. Louis?

What is the cheapest month to book a flight from Maine to St. Louis?

Traveling to a place near St. Louis?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Maine to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Maine to St. Louis

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Maine to St. Louis
Explore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.