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St. Louis

$68+ Cheap flights from Maine to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Maine to St. Louis

Cheapest flights from Maine to St. Louis
Explore the most affordable flight options available from Maine to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:36 amBOS - STL
1 stop10h 47mAmerican Airlines
Sat 1/310:01 amSTL - BOS
Nonstop2h 42mAmerican Airlines
Deal found 10/30$329
This Priceline deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:00 amBOS - STL
1 stop9h 29mFrontier
Tue 11/253:14 pmSTL - BOS
1 stop8h 30mFrontier
Deal found 10/30$330
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:11 pmBOS - STL
1 stop13h 48mMultiple Airlines
Fri 12/1210:42 amSTL - BOS
2 stops12h 14mMultiple Airlines
Deal found 10/28$332
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:08 amBOS - STL
1 stop12h 25mMultiple Airlines
Sat 12/137:43 pmSTL - BOS
2 stops13h 39mMultiple Airlines
Deal found 10/28$333
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:16 amBOS - STL
1 stop12h 41mSpirit Airlines
Thu 11/2010:53 amSTL - BOS
3 stops28h 57mSpirit Airlines
Deal found 10/30$334
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/511:08 amBOS - STL
1 stop12h 25mMultiple Airlines
Sat 12/137:43 pmSTL - BOS
2 stops13h 39mMultiple Airlines
Deal found 10/28$335
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:55 amBOS - STL
2 stops24h 12mFrontier
Thu 11/132:12 pmSTL - BOS
1 stop17h 16mFrontier
Deal found 10/29$337
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:00 amBOS - STL
1 stop28h 40mFrontier
Sat 1/37:43 pmSTL - BOS
2 stops34h 40mFrontier
Deal found 10/29$338
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:16 amBOS - STL
2 stops28h 56mMultiple Airlines
Sat 11/154:33 pmSTL - BOS
1 stop18h 31mMultiple Airlines
Deal found 10/29$340
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:26 pmBOS - STL
3 stops25h 10mMultiple Airlines
Sat 11/229:52 amSTL - BOS
1 stop13h 01mMultiple Airlines
Deal found 10/28$342
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/269:54 pmBOS - STL
1 stop17h 35mMultiple Airlines
Wed 12/37:43 pmSTL - BOS
2 stops13h 39mMultiple Airlines
Deal found 10/27$343
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:16 amBGR - STL
1 stop8h 24mDelta
Sun 11/162:36 pmSTL - BGR
2 stops7h 52mDelta
Deal found 10/28$359

Cheap flight deals from Maine to St. Louis

Keep the following information in mind while searching for Maine to St. Louis flight deals. Data was last updated October 30, 2025.

Most accurate provider

Gotogate
3 stars

Most trusted provider

Gotogate
3 stars

Round-trip from

$299
(Delta)

One-way from

$68
(Trip.com)

Popular in

December

Cheapest in

February

Average price

$364
Provider with most accurate pricing for Portland-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Lambert-St Louis flights.
Search Deals
From Maine to Lambert-St Louis
Search Deals
One-way flight from Maine to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($55 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maine to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Maine to St. Louis that are best for you.

Fly from

Maine

Fly to

St. Louis

Route

Depart

Return

Price

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 1/8

6:00 am-12:25 pm

1 stop7h 25m

Lambert-St Louis

Tue 1/13

5:29 pm-11:22 pm

1 stop4h 53m

$299

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 1/8

6:00 am-2:30 pm

2 stops9h 30m

Lambert-St Louis

Tue 1/13

8:05 am-2:39 pm

1 stop5h 34m

$304

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Wed 12/17

7:20 am-9:30 am

Nonstop3h 10m

Lambert-St Louis

Wed 1/7

5:55 pm-9:25 pm

Nonstop2h 30m

$349

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Thu 12/4

7:20 am-9:30 am

Nonstop3h 10m

Lambert-St Louis

Mon 12/8

8:15 am-11:45 am

Nonstop2h 30m

$349

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 2/26

6:00 am-11:55 am

1 stop6h 55m

Lambert-St Louis

Sun 3/1

6:45 am-11:57 am

1 stop4h 12m

$353

BangorSt. Louis

BGR - STL

BGRSTL

Bangor

Wed 11/12

5:16 am-12:40 pm

1 stop8h 24m

Lambert-St Louis

Sun 11/16

2:36 pm-11:28 pm

2 stops7h 52m

$359

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Thu 11/27

12:15 pm-6:35 pm

1 stop7h 20m

Lambert-St Louis

Mon 12/1

7:02 pm-1:26 am

1 stop5h 24m

$384

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Fri 12/19

5:29 am-9:50 am

1 stop5h 21m

Lambert-St Louis

Thu 12/25

10:04 am-5:56 pm

1 stop6h 52m

$384

BangorSt. Louis

BGR - STL

BGRSTL

Bangor

Fri 11/7

6:00 am-10:28 am

1 stop5h 28m

Lambert-St Louis

Mon 11/10

9:50 am-4:33 pm

1 stop5h 43m

$399

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Tue 4/28

7:06 am-8:47 pm

1 stop14h 41m

Lambert-St Louis

Mon 5/4

6:38 am-12:00 pm

1 stop4h 22m

$402

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 49 results
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Best time to book a flight from Maine to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to St. Louis

What is the cheapest month to book a flight from Maine to St. Louis?

Currently, October is the cheapest month in which you can book a flight from Maine to St. Louis (average of $180). Flying from Maine to St. Louis in January is currently the most expensive (average of $371). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ME to STL?

Find hourly flight availability from Maine to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

When flying from Maine to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 48% versus a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Maine to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Maine?

    If you book a flight to St. Louis from Maine, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.

  • How long is the flight from Maine to St. Louis?

    Delta, United Airlines, and Southwest can get you from Maine to St. Louis in just under 3h 10m. Your travel time can differ by up to 6h 20m. The distance from Maine to St. Louis is about 1043 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Maine to St. Louis one-way?

    One-way options have recently been found by users for as low as $154 on Delta. Other airlines that offer cheap prices include Southwest from $154 and American Airlines from $216 one-way.

  • What are the most popular routes from Maine to St. Louis?

    Most travelers choose Boston Logan Intl - Lambert-St Louis, Portland - Lambert-St Louis or Bangor - Lambert-St Louis when deciding on the best route from Maine to St. Louis.

  • Can I find deals for flights from Maine to St. Louis that include hotel bookings?

    Yes. In addition to deals on Maine to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to St. Louis.

  • Can I find deals for business class flights from Maine to St. Louis?

    Yes. Cheapflights offers flight deals from Maine to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to St. Louis?

    Currently, October is the cheapest month in which you can book a flight from Maine to St. Louis (average of $180). Flying from Maine to St. Louis in January is currently the most expensive (average of $371). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Maine to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Maine to St. Louis

Discover the top 3 airlines that operate flights from Maine to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$362FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$258Average$455FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$371Average$417FlexibilityNo cancel feeOn-time63%

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