$89+ Cheap flights from Indianapolis (IND) to Spartanburg, SC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CLT
Sep 22 — Sep 291
Round-trip
1 adult, Economy
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Find cheap flights from Indianapolis to Spartanburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Indianapolis to Spartanburg are usually found in October or September, booked 38 days in advance, depart on a Wednesday or Thursday and return on a Wednesday
Cheap flight deals from Indianapolis to Spartanburg
Cheapest
Best
Last-minute
One-way
Cheapest flights from Indianapolis to SpartanburgExplore the most affordable flight options available from Indianapolis to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
Explore the most affordable flight options available from Indianapolis to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
This Frontier deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:26 am -
1 stop7h 55m
Mon 9/219:32 am -
1 stop10h 59m
Deal found 8/19![Frontier logo]()
$178
This Super.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:26 am -
1 stop7h 55m
Thu 9/249:40 pm -
1 stop22h 51m
Deal found 8/19![Frontier logo]()
$185
This CheapOair deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:41 pm -
1 stop12h 54m
Mon 9/147:54 pm -
1 stop19h 23m
Deal found 8/18![Frontier logo]()
$188
This Super.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:12 pm -
1 stop26h 47m
Sat 10/104:47 pm -
1 stop19h 14m
Deal found 8/18![Frontier logo]()
$190
This Expedia deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:20 pm -
1 stop11h 15m
Mon 9/219:40 pm -
1 stop12h 45m
Deal found 8/19![Frontier logo]()
$191
This CheapOair deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:42 pm -
1 stop23h 04m
Fri 11/68:11 pm -
1 stop13h 38m
Deal found 8/18![Frontier logo]()
$201
This Expedia deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:41 pm -
1 stop22h 40m
Sun 9/139:40 pm -
1 stop12h 45m
Deal found 8/19![Frontier logo]()
$204
This Expedia deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/134:12 pm -
1 stop26h 47m
Thu 9/179:40 pm -
1 stop12h 45m
Deal found 8/19![Frontier logo]()
$209
This CheapOair deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/712:15 pm -
1 stop19h 46m
Tue 9/89:52 pm -
1 stop12h 33m
Deal found 8/18![Frontier logo]()
$214
This Expedia deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:20 pm -
1 stop17h 56m
Sun 9/209:40 pm -
1 stop12h 45m
Deal found 8/18![Frontier logo]()
$217
This CheapOair deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:21 am -
1 stop21h 14m
Wed 9/239:40 pm -
1 stop11h 51m
Deal found 8/19![Frontier logo]()
$219
This CheapOair deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:27 pm -
1 stop14h 08m
Tue 9/299:32 am -
1 stop24h 53m
Deal found 8/22![Frontier logo]()
$220
Best flights from Indianapolis to SpartanburgDiscover carefully curated flight deals from Indianapolis to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
Discover carefully curated flight deals from Indianapolis to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:45 am -
1 stop4h 30m
Mon 11/911:30 am -
2 stops11h 05m
Deal found 8/20![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:00 pm -
1 stop4h 54m
Sun 11/226:00 am -
1 stop3h 52m
Deal found 8/19![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:55 pm -
1 stop4h 10m
Sat 10/246:30 am -
2 stops5h 55m
Deal found 8/21![Southwest logo]()
$317
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:25 pm -
1 stop3h 20m
Wed 10/146:40 am -
2 stops8h 05m
Deal found 8/18![Southwest logo]()
$321
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:15 am -
2 stops5h 50m
Thu 10/291:35 pm -
2 stops10h 35m
Deal found 8/19![Southwest logo]()
$327
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:40 am -
2 stops11h 25m
Wed 9/236:50 am -
2 stops10h 05m
Deal found 8/19![Southwest logo]()
$332
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:50 am -
2 stops12h 00m
Mon 11/2311:30 am -
2 stops11h 05m
Deal found 8/23![Southwest logo]()
$347
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:45 am -
2 stops7h 40m
Sun 11/227:45 am -
1 stop4h 40m
Deal found 8/22![Southwest logo]()
$365
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:30 am -
1 stop4h 30m
Mon 12/217:55 am -
1 stop5h 10m
Deal found 8/22![Southwest logo]()
$390
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:55 am -
2 stops10h 40m
Mon 9/286:35 am -
2 stops8h 15m
Deal found 8/18![Southwest logo]()
$396
Last-minute flights from Indianapolis to SpartanburgDiscover last-minute flight deals from Indianapolis to Spartanburg. Data last updated August 23, 2026 and is based on user searches.
Discover last-minute flight deals from Indianapolis to Spartanburg. Data last updated August 23, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/712:15 pm -
1 stop19h 46m
Tue 9/89:52 pm -
1 stop12h 33m
Deal found 8/18![Frontier logo]()
$214
This Super.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:33 pm -
1 stop12h 28m
Tue 9/229:40 pm -
1 stop12h 45m
Deal found 8/18![Frontier logo]()
$221
This CheapOair deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:41 pm -
1 stop12h 54m
Mon 9/147:54 pm -
1 stop19h 23m
Deal found 8/18![Frontier logo]()
$188
This Expedia deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:41 pm -
1 stop22h 40m
Sun 9/139:40 pm -
1 stop12h 45m
Deal found 8/19![Frontier logo]()
$204
This CheapOair deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:20 pm -
1 stop11h 15m
Mon 9/149:40 pm -
1 stop12h 45m
Deal found 8/19![Frontier logo]()
$201
This Expedia deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/134:12 pm -
1 stop26h 47m
Thu 9/179:40 pm -
1 stop12h 45m
Deal found 8/19![Frontier logo]()
$209
This CheapOair deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:21 am -
1 stop21h 14m
Wed 9/239:40 pm -
1 stop11h 51m
Deal found 8/19![Frontier logo]()
$219
This Frontier deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:26 am -
1 stop7h 55m
Mon 9/219:32 am -
1 stop10h 59m
Deal found 8/19![Frontier logo]()
$178
This Super.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:26 am -
1 stop7h 55m
Thu 9/249:40 pm -
1 stop22h 51m
Deal found 8/19![Frontier logo]()
$185
This Expedia deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:20 pm -
1 stop11h 15m
Mon 9/219:40 pm -
1 stop12h 45m
Deal found 8/19![Frontier logo]()
$191
This Expedia deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:20 pm -
1 stop17h 56m
Sun 9/209:40 pm -
1 stop12h 45m
Deal found 8/18![Frontier logo]()
$217
This CheapOair deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:27 pm -
1 stop14h 08m
Tue 9/299:32 am -
1 stop24h 53m
Deal found 8/22![Frontier logo]()
$220
One-way flights from Indianapolis to SpartanburgSearch for one-way flight options from Indianapolis to Spartanburg. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
Search for one-way flight options from Indianapolis to Spartanburg. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
This Frontier deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:10 pm -
1 stop6h 45m
Deal found 8/18![Frontier logo]()
$89
This Expedia deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:12 pm -
1 stop26h 47m
Deal found 8/18![Frontier logo]()
$95
This CheapOair deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:21 am -
1 stop21h 14m
Deal found 8/18![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:48 pm -
2 stops36h 47m
Deal found 8/21![Frontier logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:59 pm -
2 stops17h 29m
Deal found 8/21![Frontier logo]()
$98
This Frontier deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:25 am -
1 stop5h 40m
Deal found 8/21![Frontier logo]()
$105
This CheapOair deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:20 pm -
1 stop17h 56m
Deal found 8/19![Frontier logo]()
$107
This CheapOair deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:27 pm -
1 stop14h 08m
Deal found 8/20![Frontier logo]()
$112
Find flight deals from Indianapolis to Spartanburg
Keep the following information in mind while searching for Indianapolis to Spartanburg flight deals. Data was last updated August 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $178 (Frontier) |
One-way from | $89 (Frontier) |
Popular in | August |
Cheapest in | October |
Average price | $523 |
Cheapflights Fare Finder
Customize your flight search to find flights from Indianapolis to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
Use the filters below to find and compare flights from Indianapolis to Spartanburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IndianapolisCharlotte
IND Indianapolis - CLT Charlotte Douglas
INDCLT
Indianapolis
Sat 11/7
5:45 am-10:15 am
1 stop4h 30m
Charlotte Douglas
Mon 11/9
11:30 am-10:35 pm
2 stops11h 05m
$282
IndianapolisCharlotte
IND Indianapolis - CLT Charlotte Douglas
INDCLT
Indianapolis
Wed 10/21
4:55 pm-9:05 pm
1 stop4h 10m
Charlotte Douglas
Sat 10/24
6:30 am-12:25 pm
2 stops5h 55m
$317
IndianapolisCharlotte
IND Indianapolis - CLT Charlotte Douglas
INDCLT
Indianapolis
Mon 10/12
7:25 pm-10:45 pm
1 stop3h 20m
Charlotte Douglas
Wed 10/14
6:40 am-2:45 pm
2 stops8h 05m
$321
IndianapolisCharlotte
IND Indianapolis - CLT Charlotte Douglas
INDCLT
Indianapolis
Sat 10/24
7:15 am-1:05 pm
2 stops5h 50m
Charlotte Douglas
Thu 10/29
1:35 pm-12:10 am
2 stops10h 35m
$327
IndianapolisCharlotte
IND Indianapolis - CLT Charlotte Douglas
INDCLT
Indianapolis
Wed 9/16
7:40 am-7:05 pm
2 stops11h 25m
Charlotte Douglas
Wed 9/23
6:50 am-4:55 pm
2 stops10h 05m
$332
Quickest round-trip
IndianapolisCharlotte
IND Indianapolis - CLT Charlotte Douglas
INDCLT
Indianapolis
Fri 11/20
5:00 pm-9:54 pm
1 stop4h 54m
Charlotte Douglas
Sun 11/22
6:00 am-9:52 am
1 stop3h 52m
$339
IndianapolisCharlotte
IND Indianapolis - CLT Charlotte Douglas
INDCLT
Indianapolis
Fri 11/13
6:50 am-6:50 pm
2 stops12h 00m
Charlotte Douglas
Mon 11/23
11:30 am-10:35 pm
2 stops11h 05m
$347
IndianapolisCharlotte
IND Indianapolis - CLT Charlotte Douglas
INDCLT
Indianapolis
Thu 11/19
6:45 am-2:25 pm
2 stops7h 40m
Charlotte Douglas
Sun 11/22
7:45 am-12:25 pm
1 stop4h 40m
$365
IndianapolisCharlotte
IND Indianapolis - CLT Charlotte Douglas
INDCLT
Indianapolis
Fri 12/18
5:30 am-10:00 am
1 stop4h 30m
Charlotte Douglas
Mon 12/21
7:55 am-1:05 pm
1 stop5h 10m
$390
IndianapolisCharlotte
IND Indianapolis - CLT Charlotte Douglas
INDCLT
Indianapolis
Fri 9/25
6:55 am-5:35 pm
2 stops10h 40m
Charlotte Douglas
Mon 9/28
6:35 am-2:50 pm
2 stops8h 15m
$396
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Indianapolis to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Indianapolis with our price prediction graph.
IND-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indianapolis to Spartanburg
IND-SB1
IND-CLT
What is the cheapest time of day to fly from IND to SB1?
Find hourly flight availability from Indianapolis to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 23, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 20% on flights from Indianapolis to Spartanburg by exploring options for tickets in the morning.
How much does it cost to fly round-trip from Indianapolis to Spartanburg?
Airfare is below average for this route at the moment.
Indianapolis to Spartanburg flights typically cost between $292 and $508 in September.The cheapest round-trip price found within the last 5 days was $178 on Frontier (Sep 17-Sep 21).
What is the cheapest day to fly from Indianapolis to Spartanburg?
Use this chart to determine the cheapest time to fly round-trip from Indianapolis to Spartanburg. Price data was last updated on August 22, 2026.
Travelers seeking maximum savings on their Indianapolis to Spartanburg flight should consider departing on Thursday mornings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated August 23, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Indianapolis to Spartanburg to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Indianapolis to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Indianapolis to Spartanburg
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Complete your trip to Spartanburg by adding a car rental and/or hotel reservation to your travel itinerary.
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Indianapolis and Spartanburg flights
Browse other Indianapolis and Spartanburg flight options. Last updated on August 23, 2026.
Other flights from Indianapolis
Browse through other flights departing from Indianapolis. Flights are based on user searches made on Cheapflights and were last updated on August 23, 2026.
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Indianapolis to Spartanburg flights
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Top 5 airlines flying from Indianapolis to Spartanburg
Discover the top 5 airlines that operate flights from Indianapolis to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$73 | Average$329 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$111 | Average$308 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$190 | Average$347 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$204 | Average$423 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$370 | FlexibilityNo cancel fee | On-time63% |