HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Spartanburg

$67+ Cheap flights from Indianapolis (IND) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CLT
Mar 20 — Mar 271
Fri 3/20
Fri 3/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indianapolis to Spartanburg with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Indianapolis to Spartanburg are usually found in September or August, booked 81 days in advance, depart on a Wednesday or Thursday and return on a Thursday

Cheap flight deals from Indianapolis to Spartanburg

Cheapest flights from Indianapolis to Spartanburg
Explore the most affordable flight options available from Indianapolis to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.

This Expedia deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:07 am
IND
-
CLT
1 stop7h 28m
Frontier
Mon 4/208:56 am
CLT
-
IND
1 stop5h 59m
Frontier
Deal found 2/14$99
This Mytrip deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:00 am
IND
-
CLT
1 stop7h 52m
Spirit Airlines
Wed 3/259:18 am
CLT
-
IND
1 stop13h 57m
Spirit Airlines
Deal found 2/16$137
This Mytrip deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:00 am
IND
-
CLT
1 stop7h 52m
Spirit Airlines
Tue 3/243:12 pm
CLT
-
IND
1 stop8h 03m
Spirit Airlines
Deal found 2/16$138
This CheapOair deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:00 am
IND
-
CLT
1 stop7h 43m
Spirit Airlines
Tue 3/179:18 am
CLT
-
IND
1 stop13h 57m
Spirit Airlines
Deal found 2/17$144
This Mytrip deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
IND
-
CLT
1 stop7h 52m
Spirit Airlines
Fri 4/1711:15 am
CLT
-
IND
1 stop12h 53m
Spirit Airlines
Deal found 2/16$145
This CheapOair deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
IND
-
CLT
1 stop17h 53m
Spirit Airlines
Tue 4/149:18 am
CLT
-
IND
1 stop13h 57m
Spirit Airlines
Deal found 2/17$149
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:00 am
IND
-
CLT
1 stop7h 52m
Spirit Airlines
Wed 3/189:18 am
CLT
-
IND
1 stop13h 57m
Spirit Airlines
Deal found 2/16$150
This Expedia deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
IND
-
CLT
1 stop7h 52m
Multiple Airlines
Mon 4/137:45 pm
CLT
-
IND
1 stop15h 26m
Multiple Airlines
Deal found 2/16$152
This Priceline deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:00 am
IND
-
CLT
1 stop7h 52m
Multiple Airlines
Wed 3/258:56 am
CLT
-
IND
1 stop7h 49m
Multiple Airlines
Deal found 2/14$158

Find flight deals from Indianapolis to Spartanburg

Keep the following information in mind while searching for Indianapolis to Spartanburg flight deals. Data was last updated February 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$99
(Expedia)

One-way from

$67
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$386
Provider with most accurate pricing for Indianapolis-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Charlotte Douglas flights.
Search Deals
From Indianapolis to Spartanburg
Search Deals
One-way flight from Indianapolis to Spartanburg
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($90 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from Indianapolis to Spartanburg that are best for you.

Fly from

Indianapolis

Fly to

Spartanburg

Route

Depart

Return

Price

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Sat 4/11

6:00 am-11:53 pm

1 stop17h 53m

Charlotte Douglas

Mon 4/13

9:17 pm-11:15 pm

1 stop25h 58m

$178

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Thu 4/23

8:33 pm-6:54 pm

1 stop22h 21m

Charlotte Douglas

Sun 4/26

5:41 pm-8:08 am

1 stop14h 27m

$192

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Mon 3/16

5:08 pm-10:11 am

1 stop17h 03m

Charlotte Douglas

Mon 3/23

9:17 pm-11:15 pm

1 stop25h 58m

$193

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Mon 3/16

6:41 pm-2:17 pm

1 stop19h 36m

Charlotte Douglas

Mon 3/23

9:17 pm-11:15 pm

1 stop25h 58m

$200

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Mon 3/2

6:10 pm-1:51 pm

1 stop19h 41m

Charlotte Douglas

Fri 3/6

10:46 pm-10:16 am

2 stops35h 30m

$235

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Thu 3/26

7:20 pm-10:50 pm

1 stop3h 30m

Charlotte Douglas

Tue 3/31

6:10 am-5:15 pm

2 stops11h 05m

$255

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Thu 6/11

6:30 am-2:13 pm

1 stop7h 43m

Charlotte Douglas

Sun 6/14

6:30 am-2:09 pm

1 stop7h 39m

$275

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Fri 3/13

7:23 pm-9:00 am

1 stop13h 37m

Charlotte Douglas

Mon 3/16

9:28 pm-8:39 am

1 stop11h 11m

$275

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Thu 3/12

6:00 am-1:52 pm

1 stop7h 52m

Charlotte Douglas

Sun 3/15

9:17 pm-11:15 pm

1 stop25h 58m

$276

IndianapolisCharlotte

IND - CLT

INDCLT

Indianapolis

Thu 3/12

6:00 am-1:52 pm

1 stop7h 52m

Charlotte Douglas

Tue 3/17

9:18 am-11:15 pm

1 stop13h 57m

$277

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/17

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from Indianapolis to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Spartanburg

How far ahead should I book a flight from Indianapolis to Spartanburg?

Use this chart to determine the optimal time to book a round-trip flight from Indianapolis to Spartanburg. Price data was last updated on February 13, 2026.

Booking 81 days in advance of your planned departure date is, on average, the best time to get cheap flights from Indianapolis to Spartanburg. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Indianapolis to Spartanburg?

Currently, December is the cheapest month in which you can book a flight from Indianapolis to Spartanburg (average of $130). Flying from Indianapolis to Spartanburg in January is currently the most expensive (average of $213). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to SB1?

Find hourly flight availability from Indianapolis to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 18, 2026.

Unlike in the evening, when flights are generally more expensive, you can save up to 77% on flights from Indianapolis to Spartanburg by exploring options for tickets at noon.

What is the cheapest day to fly from Indianapolis to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Indianapolis to Spartanburg. Price data was last updated on February 17, 2026.

Travelers seeking maximum savings on their Indianapolis to Spartanburg flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated February 18, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Indianapolis to Spartanburg to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,294 reviews
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,207 reviews
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,304 reviews
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Spirit Airlines
6.3
Okay
8,470 reviews
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.7
Fair
3,048 reviews
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Spartanburg?

    Most people fly from Indianapolis (IND) if they book a flight from Indianapolis to Spartanburg. On average, Indianapolis has 3 outbound flights to Spartanburg per day from 6 airlines. Indianapolis is conveniently located just 8.3 mi from Indianapolis’s city center.

  • How popular is this Indianapolis to Spartanburg flight route?

    The Indianapolis to Spartanburg flight path was viewed by 29 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Indianapolis to Spartanburg?

    Airlines like Spirit Airlines and Frontier fly from Indianapolis to Spartanburg in about 17h 53m. The time it takes to get you to your destination can typically vary by up to 4h 28m. The distance from Indianapolis to Spartanburg is about 427 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Indianapolis to Spartanburg one-way?

    The cheapest airlines for a one-way flight from Indianapolis to Spartanburg are Spirit Airlines ($65), Delta ($93), and Southwest ($94).

  • What are the cheapest flights from Indianapolis to Spartanburg?

    The cheapest flight price from Indianapolis to Spartanburg is $148. On average you can expect to pay $370. The most popular route, (Indianapolis - Charlotte Douglas), can usually be booked for $137.

  • Can I find deals for flights from Indianapolis to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Spartanburg.

  • Can I find deals for business class flights from Indianapolis to Spartanburg?

    Yes. Cheapflights offers flight deals from Indianapolis to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Spartanburg?

    Currently, December is the cheapest month in which you can book a flight from Indianapolis to Spartanburg (average of $130). Flying from Indianapolis to Spartanburg in January is currently the most expensive (average of $213). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indianapolis to Spartanburg

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Charleston flights
O'Hare Intl to Charlotte flights
O'Hare Intl to Savannah flights
O'Hare Intl to Myrtle Beach flights
Midway to Charleston flights
O'Hare Intl to Greenville flights
Midway to Savannah flights
Midway to Charlotte flights
O'Hare Intl to Columbia flights
Cincinnati to Charlotte flights
O'Hare Intl to Hilton Head Island flights
Indianapolis to Charlotte flights
Cincinnati to Savannah flights
Indianapolis to Charleston flights
Midway to Myrtle Beach flights
Louisville to Charleston flights
Cincinnati to Charleston flights
Dayton to Charleston flights
Cincinnati to Myrtle Beach flights
South Bend to Savannah flights
Indianapolis to Myrtle Beach flights
Dayton to Charlotte flights
Louisville to Savannah flights
Midway to Greenville flights
Dayton to Myrtle Beach flights
Fort Wayne to Charlotte flights
Midway to Columbia flights
Louisville to Charlotte flights
Cincinnati to Hilton Head Island flights
South Bend to Charlotte flights
Indianapolis to Savannah flights
Dayton to Savannah flights
Fort Wayne to Myrtle Beach flights
Cincinnati to Greenville flights
Indianapolis to Hilton Head Island flights
South Bend to Charleston flights
O'Hare Intl to Augusta flights
Fort Wayne to Savannah flights
Dayton to Greenville flights
Louisville to Myrtle Beach flights
Louisville to Columbia flights
South Bend to Myrtle Beach flights
Fort Wayne to Charleston flights
Cincinnati to Columbia flights
Indianapolis to Greenville flights
Dayton to Columbia flights
Louisville to Hilton Head Island flights
Kalamazoo to Myrtle Beach flights
Indianapolis to Columbia flights
Kalamazoo to Savannah flights

Top 6 airlines flying from Indianapolis to Spartanburg

Discover the top 6 airlines that operate flights from Indianapolis to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$108Average$173FlexibilityNo cancel feeOn-time65%
FrontierCheapest$110Average$198FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$139Average$373FlexibilityNo cancel feeOn-time71%
DeltaCheapest$189Average$326FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$200Average$414FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$228Average$396FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.