HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$119+ Cheap flights from Sioux Falls (FSD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — CHS
3月 6 — 3月 131
金 3/6
金 3/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Sioux Falls to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Sioux Falls to South Carolina

Cheapest flights from Sioux Falls to South Carolina
Explore the most affordable flight options available from Sioux Falls to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 2月 4, 2026.

This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
水 3/45:00 am
FSD
-
CLT
1 stop6h 26m
Delta
水 3/116:18 am
CLT
-
FSD
1 stop7h 35m
Delta
Deal found 2/4$265
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
火 3/35:00 am
FSD
-
CLT
2 stops10h 05m
Delta
火 3/106:18 am
CLT
-
FSD
1 stop5h 03m
Delta
Deal found 2/1$270
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
火 3/312:14 pm
FSD
-
MYR
2 stops7h 31m
American Airlines
火 3/106:01 am
MYR
-
FSD
2 stops8h 35m
American Airlines
Deal found 2/3$275
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
土 4/181:41 pm
FSD
-
SAV
1 stop7h 50m
American Airlines
水 4/225:40 am
SAV
-
FSD
1 stop7h 19m
American Airlines
Deal found 2/3$279
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
土 9/265:15 am
FSD
-
CLT
1 stop4h 47m
Delta
月 9/286:50 pm
CLT
-
FSD
1 stop4h 56m
Delta
Deal found 2/3$279
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
金 2/271:26 pm
FSD
-
CHS
1 stop8h 03m
American Airlines
火 3/312:23 pm
CHS
-
FSD
1 stop7h 47m
American Airlines
Deal found 2/2$279
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
水 8/55:25 am
FSD
-
CHS
1 stop4h 59m
Delta
土 8/85:55 pm
CHS
-
FSD
1 stop5h 16m
Delta
Deal found 2/4$283
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
土 5/239:15 am
FSD
-
CLT
1 stop6h 13m
Delta
土 5/3011:26 am
CLT
-
FSD
1 stop5h 13m
Delta
Deal found 2/1$291
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
土 2/214:19 pm
FSD
-
CLT
1 stop6h 02m
Delta
月 2/236:59 pm
CLT
-
FSD
1 stop5h 31m
Delta
Deal found 2/1$294
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
土 4/41:26 pm
FSD
-
SAV
1 stop7h 49m
American Airlines
土 4/115:40 am
SAV
-
FSD
1 stop7h 19m
American Airlines
Deal found 2/2$307
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
金 11/135:15 am
FSD
-
CLT
1 stop4h 52m
Delta
月 11/166:50 pm
CLT
-
FSD
1 stop5h 01m
Delta
Deal found 2/2$309
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
水 2/181:26 pm
FSD
-
CHS
1 stop8h 03m
American Airlines
土 2/217:10 am
CHS
-
FSD
1 stop5h 32m
American Airlines
Deal found 2/4$309

Find flight deals from Sioux Falls to South Carolina

Keep the following information in mind while searching for Sioux Falls to South Carolina flight deals. Data was last updated 2月 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$265
(Delta)

One-way from

$119
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$339
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Myrtle Beach Intl flights.
Search Deals
From Sioux Falls Joe Foss Field to South Carolina
Search Deals
One-way flight from Sioux Falls Joe Foss Field to South Carolina
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($11 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 2月 4, 2026.
Use the filters below to find and compare flights from Sioux Falls to South Carolina that are best for you.

Fly from

Sioux Falls

Fly to

South Carolina

Route

Depart

Return

Price

Sioux FallsCharlotte

FSD - CLT

FSDCLT

Sioux Falls Joe Foss Field

水 3/4

5:00 am-12:26 pm

1 stop6h 26m

Charlotte Douglas

水 3/11

6:18 am-12:53 pm

1 stop7h 35m

$265

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

火 3/3

12:14 pm-8:45 pm

2 stops7h 31m

Myrtle Beach Intl

火 3/10

6:01 am-1:36 pm

2 stops8h 35m

$275

Sioux FallsCharleston

FSD - CHS

FSDCHS

Sioux Falls Joe Foss Field

水 4/22

7:39 am-1:55 pm

1 stop5h 16m

Charleston

火 4/28

4:00 pm-11:44 pm

1 stop8h 44m

$279

Sioux FallsSavannah

FSD - SAV

FSDSAV

Sioux Falls Joe Foss Field

土 4/18

1:41 pm-10:31 pm

1 stop7h 50m

Savannah/Hilton Head

水 4/22

5:40 am-11:59 am

1 stop7h 19m

$279

Sioux FallsSavannah

FSD - SAV

FSDSAV

Sioux Falls Joe Foss Field

土 4/4

2:07 pm-10:48 pm

1 stop7h 41m

Savannah/Hilton Head

土 4/11

7:00 am-12:56 pm

1 stop6h 56m

$307

Sioux FallsSavannah

FSD - SAV

FSDSAV

Sioux Falls Joe Foss Field

水 2/18

11:21 am-5:47 pm

1 stop5h 26m

Savannah/Hilton Head

土 2/21

9:40 am-2:40 pm

1 stop6h 00m

$309

Sioux FallsCharleston

FSD - CHS

FSDCHS

Sioux Falls Joe Foss Field

木 2/19

7:40 am-1:52 pm

1 stop5h 12m

Charleston

月 2/23

5:05 pm-9:57 pm

1 stop5h 52m

$309

Sioux FallsSavannah

FSD - SAV

FSDSAV

Sioux Falls Joe Foss Field

火 2/17

1:22 pm-10:16 pm

1 stop7h 54m

Savannah/Hilton Head

土 2/21

7:00 am-12:42 pm

1 stop6h 42m

$309

Sioux FallsCharleston

FSD - CHS

FSDCHS

Sioux Falls Joe Foss Field

水 2/18

1:26 pm-10:29 pm

1 stop8h 03m

Charleston

土 2/21

7:10 am-11:42 am

1 stop5h 32m

$309

Sioux FallsCharleston

FSD - CHS

FSDCHS

Sioux Falls Joe Foss Field

水 2/18

7:40 am-1:52 pm

1 stop5h 12m

Charleston

土 2/21

6:00 am-10:46 am

1 stop5h 46m

$310

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 37 results
1
2
3
4

Best time to book a flight from Sioux Falls to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to South Carolina

What is the cheapest month to book a flight from Sioux Falls to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Sioux Falls to South Carolina (average of $174). Flying from Sioux Falls to South Carolina in January is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from FSD to SC?

Find hourly flight availability from Sioux Falls to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 2月 4, 2026.

One of the essential ways to save on airfare from Sioux Falls to South Carolina is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 54% on airfare.

What is the cheapest day to fly from Sioux Falls to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Sioux Falls to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their Sioux Falls to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Sioux Falls to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 2月 4, 2026.
Read through reviews of airlines operating flights from Sioux Falls to South Carolina, such as Delta, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,144 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,144 reviews
Delta
7.9
Good
8,144 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,236 reviews
Delta
7.9
Good
8,144 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,222 reviews
Delta
7.9
Good
8,144 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to South Carolina?

    Sioux Falls Joe Foss Field (FSD) is the airport you will fly out of if you book a flight from Sioux Falls to South Carolina. It is only a 2.6 mi journey to Joe Foss Field (FSD) from Sioux Falls’s city center.

  • How long is the flight from Sioux Falls to South Carolina?

    Delta, American Airlines, and United Airlines can get you from Sioux Falls to South Carolina in just under 5h 12m. Your travel time can differ by up to 2h 19m. There are 1164 mi between Sioux Falls and South Carolina. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Sioux Falls to South Carolina?

    The most popular flight routes from Sioux Falls to South Carolina are Sioux Falls Joe Foss Field - Charlotte Douglas, Sioux Falls Joe Foss Field - Savannah/Hilton Head and Sioux Falls Joe Foss Field - Charleston.

  • Can I find deals for flights from Sioux Falls to South Carolina that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to South Carolina.

  • Can I find deals for business class flights from Sioux Falls to South Carolina?

    Yes. Cheapflights offers flight deals from Sioux Falls to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Sioux Falls to South Carolina (average of $174). Flying from Sioux Falls to South Carolina in January is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Sioux Falls to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Sioux Falls to Denver flights
Sioux Falls to Sky Harbor Intl flights
Sioux Falls to Phoenix-Mesa Gateway flights
Sioux Falls to Orlando flights
Sioux Falls to Las Vegas flights
Sioux Falls to Dallas/Fort Worth flights
Sioux Falls to Fort Myers flights
Sioux Falls to O'Hare Intl flights
Sioux Falls to Tampa flights
Sioux Falls to Charlotte flights
Sioux Falls to Pensacola flights
Sioux Falls to Salt Lake City flights
Sioux Falls to Midway flights
Sioux Falls to San Diego flights
Sioux Falls to Hobby flights
Rapid City to Dallas/Fort Worth flights
Sioux Falls to Sarasota flights
Sioux Falls to Grand Rapids flights
Rapid City to Sky Harbor Intl flights
Sioux Falls to Boston flights
Sioux Falls to John F Kennedy Intl flights
Sioux Falls to Miami flights
Sioux Falls to Atlanta flights
Sioux Falls to Los Angeles flights
Sioux Falls to Nashville flights
Sioux Falls to Portland flights
Sioux Falls to Mobile flights
Rapid City to Las Vegas flights
Sioux Falls to Raleigh flights
Rapid City to Orlando flights
Rapid City to Anchorage flights
Sioux Falls to Austin flights
Sioux Falls to George Bush Intcntl flights
Sioux Falls to Seattle flights
Rapid City to Fort Lauderdale flights
Sioux Falls to Newark flights
Rapid City to Fort Myers flights
Sioux Falls to Boise flights
Sioux Falls to Detroit flights
Sioux Falls to Savannah flights
Sioux Falls to Palm Springs flights
Sioux Falls to New Orleans flights
Rapid City to Seattle flights
Rapid City to O'Hare Intl flights
Sioux Falls to Valparaiso flights
Sioux Falls to Reno flights
Rapid City to Miami flights
Sioux Falls to Key West flights
Sioux Falls to Honolulu flights
Rapid City to Los Angeles flights

Top 3 airlines flying from Sioux Falls to South Carolina

Discover the top 3 airlines that operate flights from Sioux Falls to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 2月 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$160Average$374FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$249Average$395FlexibilityNo cancel feeOn-time71%
DeltaCheapest$250Average$377FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.