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South Carolina

$161+ Cheap flights from Sioux Falls (FSD) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — CHS
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Cheap flight deals from Sioux Falls to South Carolina

Cheapest flights from Sioux Falls to South Carolina
Explore the most affordable flight options available from Sioux Falls to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:06 pm
FSD
-
CLT
1 stop19h 50m
Frontier
Thu 4/236:18 pm
CLT
-
FSD
1 stop26h 03m
Frontier
Deal found 3/20$161
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:46 pm
FSD
-
CLT
1 stop13h 35m
Multiple Airlines
Fri 4/109:05 am
CLT
-
FSD
1 stop9h 16m
Multiple Airlines
Deal found 3/21$234
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:06 pm
FSD
-
CLT
1 stop19h 50m
Frontier
Sun 4/196:18 pm
CLT
-
FSD
1 stop26h 03m
Frontier
Deal found 3/21$236
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:11 pm
FSD
-
CLT
1 stop13h 59m
Multiple Airlines
Mon 5/48:56 am
CLT
-
FSD
1 stop9h 25m
Multiple Airlines
Deal found 3/18$252
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:11 pm
FSD
-
CLT
1 stop13h 59m
Multiple Airlines
Mon 4/278:56 am
CLT
-
FSD
1 stop9h 25m
Multiple Airlines
Deal found 3/21$254
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:11 pm
FSD
-
CLT
1 stop13h 59m
Multiple Airlines
Mon 4/278:56 am
CLT
-
FSD
1 stop9h 25m
Multiple Airlines
Deal found 3/19$259
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:11 pm
FSD
-
CLT
1 stop18h 43m
Multiple Airlines
Wed 5/207:58 pm
CLT
-
FSD
1 stop23h 14m
Multiple Airlines
Deal found 3/17$260
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:11 pm
FSD
-
CLT
1 stop16h 54m
Multiple Airlines
Wed 5/207:58 pm
CLT
-
FSD
1 stop23h 14m
Multiple Airlines
Deal found 3/17$266
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:11 pm
FSD
-
CLT
1 stop13h 59m
Multiple Airlines
Sun 5/312:50 pm
CLT
-
FSD
1 stop29h 31m
Multiple Airlines
Deal found 3/20$268
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:11 pm
FSD
-
MYR
1 stop24h 22m
Multiple Airlines
Fri 5/810:00 am
MYR
-
FSD
1 stop8h 21m
Multiple Airlines
Deal found 3/20$279
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:39 am
FSD
-
MYR
1 stop5h 38m
United Airlines
Wed 4/223:15 pm
MYR
-
FSD
1 stop7h 39m
United Airlines
Deal found 3/17$291
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:19 am
FSD
-
CLT
1 stop4h 13m
Delta
Wed 5/206:16 am
CLT
-
FSD
1 stop7h 33m
Delta
Deal found 3/17$291

Find flight deals from Sioux Falls to South Carolina

Keep the following information in mind while searching for Sioux Falls to South Carolina flight deals. Data was last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$161
(Frontier)

Popular in

December

Cheapest in

November

Average price

$354
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Myrtle Beach Intl flights.
Search Deals
From Sioux Falls Joe Foss Field to South Carolina
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($0 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Sioux Falls to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Sat 4/18

7:39 am-2:17 pm

1 stop5h 38m

Myrtle Beach Intl

Wed 4/22

3:15 pm-9:54 pm

1 stop7h 39m

$291

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 4/17

6:11 pm-11:29 pm

1 stop28h 18m

Myrtle Beach Intl

Mon 4/20

9:58 am-5:21 pm

1 stop8h 23m

$323

Sioux FallsCharleston

FSD - CHS

FSDCHS

Sioux Falls Joe Foss Field

Tue 4/21

1:41 pm-10:41 pm

1 stop8h 00m

Charleston

Tue 4/28

7:00 am-12:56 pm

1 stop6h 56m

$323

Sioux FallsHilton Head Island

FSD - HHH

FSDHHH

Sioux Falls Joe Foss Field

Sat 4/18

6:10 am-2:16 pm

1 stop7h 06m

Hilton Head Island

Wed 4/22

3:05 pm-9:54 pm

1 stop7h 49m

$323

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Sat 4/25

7:39 am-5:09 pm

2 stops8h 30m

Myrtle Beach Intl

Sat 5/2

3:14 pm-9:52 pm

1 stop7h 38m

$330

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Sat 5/9

7:30 am-2:18 pm

1 stop5h 48m

Myrtle Beach Intl

Thu 5/14

3:14 pm-9:52 pm

1 stop7h 38m

$335

Sioux FallsCharlotte

FSD - CLT

FSDCLT

Sioux Falls Joe Foss Field

Fri 5/8

8:19 am-1:32 pm

1 stop4h 13m

Charlotte Douglas

Fri 8/21

6:20 am-12:28 pm

1 stop7h 08m

$339

Sioux FallsCharlotte

FSD - CLT

FSDCLT

Sioux Falls Joe Foss Field

Thu 6/18

8:15 am-2:06 pm

1 stop4h 51m

Charlotte Douglas

Sun 6/21

6:20 am-12:28 pm

1 stop7h 08m

$339

Sioux FallsSavannah

FSD - SAV

FSDSAV

Sioux Falls Joe Foss Field

Sat 5/2

3:15 pm-9:13 pm

1 stop4h 58m

Savannah/Hilton Head

Sat 5/9

8:08 am-2:38 pm

1 stop7h 30m

$339

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 9/15

7:40 am-2:15 pm

1 stop5h 35m

Myrtle Beach Intl

Sat 9/19

3:21 pm-9:52 pm

1 stop7h 31m

$339

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/19

Showing 1-10 of 37 resultsSorted by cheapest first
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Best time to book a flight from Sioux Falls to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to South Carolina

What is the cheapest month to book a flight from Sioux Falls to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Sioux Falls to South Carolina (average of $174). Flying from Sioux Falls to South Carolina in February is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from FSD to SC?

Find hourly flight availability from Sioux Falls to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 22, 2026.

One of the essential ways to save on airfare from Sioux Falls to South Carolina is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 54% on airfare.

What is the cheapest day to fly from Sioux Falls to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Sioux Falls to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their Sioux Falls to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 22, 2026.
Read through reviews of airlines operating flights from Sioux Falls to South Carolina, such as Delta,United Airlines, andAmerican Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,314 reviews

Overall

7.9

Food

7.2

Comfort

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,314 reviews
Delta
7.9
Good
8,314 reviews

Overall

7.9

Food

7.2

Comfort

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,455 reviews
Delta
7.9
Good
8,314 reviews

Overall

7.9

Food

7.2

Comfort

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,489 reviews
Delta
7.9
Good
8,314 reviews

Overall

7.9

Food

7.2

Comfort

7.9

Entertainment

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to South Carolina?

    Sioux Falls Joe Foss Field (FSD) is the airport you will fly out of if you book a flight from Sioux Falls to South Carolina. It is only a 2.6 mi journey to Joe Foss Field (FSD) from Sioux Falls’s city center.

  • How long is the flight from Sioux Falls to South Carolina?

    United Airlines, American Airlines, and Delta can get you from Sioux Falls to South Carolina in just under 4h 13m. Your travel time can differ by up to 3h 47m. There are 1019 mi between Sioux Falls and South Carolina. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Sioux Falls to South Carolina?

    The most popular flight routes from Sioux Falls to South Carolina are Sioux Falls Joe Foss Field - Charlotte Douglas, Sioux Falls Joe Foss Field - Charleston and Sioux Falls Joe Foss Field - Myrtle Beach Intl.

  • Can I find deals for flights from Sioux Falls to South Carolina that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to South Carolina.

  • Can I find deals for business class flights from Sioux Falls to South Carolina?

    Yes. Cheapflights offers flight deals from Sioux Falls to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Sioux Falls to South Carolina (average of $174). Flying from Sioux Falls to South Carolina in February is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Sioux Falls to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Sioux Falls to South Carolina

Discover the top 3 airlines that operate flights from Sioux Falls to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$160Average$402FlexibilityNo cancel feeOn-time69%
DeltaCheapest$250Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$382FlexibilityNo cancel feeOn-time71%

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