$274+ Cheap flights from Sioux Falls to Myrtle Beach (FSD - MYR)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/18. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — MYR
Nov 19 — Nov 261
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Myrtle Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to Myrtle Beach
Cheapest
Best
Last-minute
One-way
Cheapest flights from Sioux Falls to Myrtle BeachExplore the most affordable flight options available from Sioux Falls to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
Explore the most affordable flight options available from Sioux Falls to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:53 pm -
1 stop8h 59m
Sat 10/316:30 am -
2 stops8h 48m
Deal found 10/19![American Airlines logo]()
$494
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:16 am -
1 stop7h 17m
Mon 12/287:03 pm -
1 stop5h 38m
Deal found 10/15![Delta logo]()
$628
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/152:18 pm -
2 stops18h 27m
Sun 11/228:15 pm -
1 stop22h 33m
Deal found 10/16![Multiple Airlines logo]()
$629
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:34 pm -
2 stops15h 46m
Mon 12/2812:45 pm -
2 stops13h 01m
Deal found 10/15![American Airlines logo]()
$697
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:48 am -
2 stops8h 23m
Thu 11/511:27 am -
2 stops11h 10m
Deal found 10/17![United Airlines logo]()
$798
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:08 pm -
1 stop8h 26m
Fri 11/611:03 am -
2 stops8h 45m
Deal found 10/18![American Airlines logo]()
$821
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:18 pm -
2 stops15h 14m
Sun 11/225:10 am -
2 stops8h 23m
Deal found 10/16![American Airlines logo]()
$860
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:08 pm -
1 stop8h 26m
Thu 11/55:10 am -
2 stops10h 46m
Deal found 10/17![American Airlines logo]()
$899
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:25 am -
1 stop7h 08m
Sun 11/222:18 pm -
1 stop6h 38m
Deal found 10/16![Delta logo]()
$919
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:48 am -
2 stops8h 23m
Sat 10/3111:27 am -
3 stops11h 10m
Deal found 10/19![United Airlines logo]()
$942
Best flights from Sioux Falls to Myrtle BeachDiscover carefully curated flight deals from Sioux Falls to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
Discover carefully curated flight deals from Sioux Falls to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/11:00 pm -
2 stops9h 35m
Tue 3/92:15 pm -
2 stops7h 58m
Deal found 10/19![Delta logo]()
$443
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:30 am -
2 stops9h 18m
Tue 1/1211:27 am -
2 stops8h 11m
Deal found 10/19![United Airlines logo]()
$520
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:16 am -
1 stop7h 17m
Mon 12/287:03 pm -
1 stop5h 38m
Deal found 10/15![Delta logo]()
$628
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/156:45 am -
1 stop5h 50m
Fri 3/192:15 pm -
1 stop6h 26m
Deal found 10/17![Delta logo]()
$717
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:48 am -
2 stops8h 23m
Thu 11/511:27 am -
2 stops11h 10m
Deal found 10/17![United Airlines logo]()
$798
Last-minute flights from Sioux Falls to Myrtle BeachDiscover last-minute flight deals from Sioux Falls to Myrtle Beach. Data last updated October 20, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Myrtle Beach. Data last updated October 20, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:53 pm -
1 stop8h 59m
Sat 10/316:30 am -
2 stops8h 48m
Deal found 10/19![American Airlines logo]()
$494
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:48 am -
2 stops8h 23m
Sat 10/3111:27 am -
3 stops11h 10m
Deal found 10/19![United Airlines logo]()
$942
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:48 am -
2 stops8h 23m
Thu 11/511:27 am -
2 stops11h 10m
Deal found 10/17![United Airlines logo]()
$798
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:08 pm -
1 stop8h 26m
Thu 11/55:10 am -
2 stops10h 46m
Deal found 10/17![American Airlines logo]()
$899
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:08 pm -
1 stop8h 26m
Fri 11/611:03 am -
2 stops8h 45m
Deal found 10/18![American Airlines logo]()
$821
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/152:18 pm -
2 stops18h 27m
Sun 11/228:15 pm -
1 stop22h 33m
Deal found 10/16![Multiple Airlines logo]()
$629
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:18 pm -
2 stops15h 14m
Sun 11/225:10 am -
2 stops8h 23m
Deal found 10/16![American Airlines logo]()
$860
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:25 am -
1 stop7h 08m
Sun 11/222:18 pm -
1 stop6h 38m
Deal found 10/16![Delta logo]()
$919
One-way flights from Sioux Falls to Myrtle BeachSearch for one-way flight options from Sioux Falls to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
Search for one-way flight options from Sioux Falls to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:37 pm -
1 stop14h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:39 pm -
2 stops35h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:34 pm -
1 stop12h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2511:25 am -
1 stop21h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:16 am -
1 stop7h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:00 am -
2 stops7h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:08 pm -
1 stop8h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![American Airlines logo]()
$423
Find flight deals from Sioux Falls to Myrtle Beach
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $354 (American Airlines) |
One-way from | $274 (Kiwi.com) |
Popular in | November |
Cheapest in | August |
Average price | $749 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
Use the filters below to find and compare flights from Sioux Falls to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Fri 12/18
5:37 pm-9:28 am
1 stop14h 51m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$274
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Mon 11/2
8:39 pm-8:50 am
2 stops35h 11m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$279
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Sun 11/1
7:34 pm-8:45 am
1 stop12h 11m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$294
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Fri 12/25
11:25 am-9:28 am
1 stop21h 03m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$314
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Thu 12/17
5:16 am-1:33 pm
1 stop7h 17m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$329
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Fri 12/25
5:00 am-1:39 pm
2 stops7h 39m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$375
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Mon 3/1
1:00 pm-11:35 pm
2 stops9h 35m
Myrtle Beach Intl
Tue 3/9
2:15 pm-9:13 pm
2 stops7h 58m
$443
Quickest round-trip
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Sun 12/20
5:00 am-1:14 pm
2 stops7h 14m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$449
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Sat 1/9
7:30 am-5:48 pm
2 stops9h 18m
Myrtle Beach Intl
Tue 1/12
11:27 am-6:38 pm
2 stops8h 11m
$520
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Sun 12/20
10:33 am-4:48 pm
3 stops29h 15m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$556
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to Myrtle Beach
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Myrtle Beach in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-Myrtle Beach flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Myrtle Beach flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Myrtle Beach flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-Myrtle Beach flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Sioux Falls with our price prediction graph.
FSD-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Myrtle Beach
Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated October 20, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Sioux Falls to Myrtle Beach. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Pawleys Island
Sunset Beach
Surfside Beach
Garden City Beach
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Other flights to Myrtle Beach
Explore flights to Myrtle Beach departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.
Sioux Falls and Myrtle Beach flights
Browse other Sioux Falls and Myrtle Beach flight options. Last updated on October 20, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Sioux Falls to Myrtle Beach
Discover the top 2 airlines that operate flights from Sioux Falls to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$308 | Average$509 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$324 | Average$500 | FlexibilityNo cancel fee | On-time71% |