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Myrtle Beach

$339+ Cheap flights from Sioux Falls to Myrtle Beach (FSD - MYR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — MYR
May 22 — May 291
Fri 5/22
Fri 5/29
1 adult, Economy
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Cheap flight deals from Sioux Falls to Myrtle Beach

Cheapest flights from Sioux Falls to Myrtle Beach
Explore the most affordable flight options available from Sioux Falls to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.

This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:30 am
FSD
-
MYR
1 stop7h 07m
American Airlines
Sun 9/65:07 pm
MYR
-
FSD
1 stop8h 20m
American Airlines
Deal found 4/21$339
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:40 am
FSD
-
MYR
1 stop5h 26m
United Airlines
Wed 8/1210:28 am
MYR
-
FSD
2 stops12h 24m
United Airlines
Deal found 4/20$344
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:04 am
FSD
-
MYR
2 stops6h 56m
Delta
Wed 8/1211:10 am
MYR
-
FSD
2 stops11h 59m
Delta
Deal found 4/20$349
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
FSD
-
MYR
1 stop8h 38m
American Airlines
Tue 8/115:15 pm
MYR
-
FSD
2 stops8h 12m
American Airlines
Deal found 4/18$359
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:04 am
FSD
-
MYR
2 stops6h 56m
Delta
Thu 8/136:00 am
MYR
-
FSD
2 stops7h 28m
Delta
Deal found 4/20$364
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:30 am
FSD
-
MYR
1 stop7h 07m
American Airlines
Wed 8/125:07 pm
MYR
-
FSD
1 stop8h 20m
American Airlines
Deal found 4/20$371
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:29 pm
FSD
-
MYR
2 stops8h 27m
American Airlines
Sat 5/912:36 pm
MYR
-
FSD
1 stop7h 33m
American Airlines
Deal found 4/20$374

Find flight deals from Sioux Falls to Myrtle Beach

Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$339
(American Airlines)

Popular in

April

Cheapest in

November

Average price

$616
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Myrtle Beach Intl flights.
Search Deals
From Sioux Falls Joe Foss Field to Myrtle Beach Intl
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($67 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from Sioux Falls to Myrtle Beach that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 8/5

7:40 am-2:06 pm

1 stop5h 26m

Myrtle Beach Intl

Wed 8/12

10:28 am-9:52 pm

2 stops12h 24m

$344

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 5/6

7:30 am-2:18 pm

1 stop5h 48m

Myrtle Beach Intl

Sun 5/10

3:14 pm-9:52 pm

1 stop7h 38m

$394

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 5/5

5:25 am-12:57 pm

1 stop6h 32m

Myrtle Beach Intl

Sat 5/9

1:30 pm-7:49 pm

1 stop7h 19m

$414

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Mon 8/3

5:00 am-2:12 pm

1 stop8h 12m

Myrtle Beach Intl

Wed 8/12

3:21 pm-9:52 pm

1 stop7h 31m

$420
Quickest round-trip

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 8/5

7:40 am-2:06 pm

1 stop5h 26m

Myrtle Beach Intl

Fri 8/14

3:21 pm-9:52 pm

1 stop7h 31m

$420

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Thu 8/27

6:00 am-2:15 pm

1 stop7h 15m

Myrtle Beach Intl

Mon 8/31

3:21 pm-9:52 pm

1 stop7h 31m

$420

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 9/2

6:00 am-2:15 pm

1 stop7h 15m

Myrtle Beach Intl

Sat 9/5

3:21 pm-9:52 pm

1 stop7h 31m

$420

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Thu 8/27

7:30 am-9:51 pm

2 stops13h 21m

Myrtle Beach Intl

Mon 8/31

5:07 pm-12:27 am

1 stop8h 20m

$425

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Sun 5/31

7:02 pm-9:05 am

1 stop13h 03m

Myrtle Beach Intl

Wed 6/3

2:42 pm-6:01 pm

1 stop28h 19m

$462

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Mon 8/31

7:40 am-2:15 pm

1 stop5h 35m

Myrtle Beach Intl

Wed 9/9

10:00 am-9:52 pm

2 stops12h 52m

$462

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/20

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Compare providers for flights from Sioux Falls to Myrtle Beach

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Myrtle Beach in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Sioux Falls-Myrtle Beach flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Myrtle Beach flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Myrtle Beach flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Sioux Falls-Myrtle Beach flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Sioux Falls to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Myrtle Beach

How much does it cost to fly round-trip from Sioux Falls to Myrtle Beach?

Reviews of airlines servicing Myrtle Beach

Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated April 22, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Sioux Falls to Myrtle Beach. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,430 reviews

Crew

8.5

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,430 reviews
Delta
7.9
Good
8,430 reviews

Crew

8.5

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,647 reviews
Delta
7.9
Good
8,430 reviews

Crew

8.5

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Sioux Falls to Myrtle Beach?

    Departing from Sioux Falls to Myrtle Beach will take you 5h 26m. The distance between Sioux Falls and Myrtle Beach is about 1175 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Sioux Falls to Myrtle Beach round-trip?

    Flying on American Airlines is currently your cheapest option to Myrtle Beach, with prices starting at $256. Another option worth looking into is Delta, starting at $272 round trip. American Airlines is currently priced 40% below the average price you’ll pay for this route.

  • Can I find deals for flights from Sioux Falls to Myrtle Beach that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Myrtle Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Myrtle Beach.

  • Can I find deals for business class flights from Sioux Falls to Myrtle Beach?

    Yes. Cheapflights offers flight deals from Sioux Falls to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Conway
Surfside Beach
Pawleys Island
Little River
Garden City Beach

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Top 2 airlines flying from Sioux Falls to Myrtle Beach

Discover the top 2 airlines that operate flights from Sioux Falls to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$256Average$354FlexibilityNo cancel feeOn-time71%
DeltaCheapest$272Average$498FlexibilityNo cancel feeOn-timeN/A

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