$309+ Cheap flights from Sioux Falls to Myrtle Beach (FSD - MYR)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — MYR
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Myrtle Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to Myrtle Beach
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Cheapest flights from Sioux Falls to Myrtle BeachExplore the most affordable flight options available from Sioux Falls to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Sioux Falls to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:08 pm -
1 stop8h 26m
Sat 11/148:07 am -
2 stops11h 41m
Deal found 9/2![American Airlines logo]()
$425
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:50 am -
1 stop6h 26m
Sat 10/34:44 pm -
1 stop7h 27m
Deal found 9/3![United Airlines logo]()
$474
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:55 am -
2 stops45h 55m
Sat 10/32:35 pm -
1 stop28h 57m
Deal found 9/3![Multiple Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:08 pm -
1 stop8h 26m
Tue 11/1710:17 am -
2 stops9h 31m
Deal found 9/4![American Airlines logo]()
$485
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:06 pm -
2 stops9h 47m
Sat 10/38:08 am -
2 stops13h 37m
Deal found 9/4![American Airlines logo]()
$490
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:50 am -
1 stop6h 26m
Sat 10/34:00 pm -
1 stop8h 44m
Deal found 9/6![United Airlines logo]()
$494
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:30 am -
1 stop7h 03m
Sat 10/33:56 pm -
1 stop4h 51m
Deal found 9/5![Delta logo]()
$559
Best flights from Sioux Falls to Myrtle BeachDiscover carefully curated flight deals from Sioux Falls to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Sioux Falls to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:40 am -
2 stops8h 09m
Tue 1/1211:28 am -
2 stops11h 55m
Deal found 9/2![United Airlines logo]()
$503
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:30 am -
1 stop7h 03m
Sat 10/33:56 pm -
1 stop4h 51m
Deal found 9/5![Delta logo]()
$559
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:48 am -
3 stops25h 33m
Sat 11/1411:27 am -
2 stops11h 10m
Deal found 9/2![United Airlines logo]()
$676
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:50 am -
1 stop6h 26m
Mon 10/125:00 pm -
1 stop7h 11m
Deal found 9/6![United Airlines logo]()
$690
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:50 pm -
1 stop19h 12m
Fri 10/95:00 pm -
1 stop7h 11m
Deal found 9/4![United Airlines logo]()
$708
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:48 am -
3 stops25h 33m
Tue 11/1711:27 am -
2 stops11h 10m
Deal found 9/6![United Airlines logo]()
$733
Last-minute flights from Sioux Falls to Myrtle BeachDiscover last-minute flight deals from Sioux Falls to Myrtle Beach. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Myrtle Beach. Data last updated September 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:50 am -
1 stop6h 26m
Sat 10/34:44 pm -
1 stop7h 27m
Deal found 9/3![United Airlines logo]()
$474
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:55 am -
2 stops45h 55m
Sat 10/32:35 pm -
1 stop28h 57m
Deal found 9/3![Multiple Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:06 pm -
2 stops9h 47m
Sat 10/38:08 am -
2 stops13h 37m
Deal found 9/4![American Airlines logo]()
$490
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:50 am -
1 stop6h 26m
Sat 10/34:00 pm -
1 stop8h 44m
Deal found 9/6![United Airlines logo]()
$494
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:30 am -
1 stop7h 03m
Sat 10/33:56 pm -
1 stop4h 51m
Deal found 9/5![Delta logo]()
$559
One-way flights from Sioux Falls to Myrtle BeachSearch for one-way flight options from Sioux Falls to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Sioux Falls to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:08 pm -
1 stop8h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/84:37 pm -
3 stops42h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:50 am -
1 stop6h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:16 pm -
3 stops44h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:54 pm -
3 stops37h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:13 pm -
1 stop8h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$512
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:23 am -
2 stops8h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$515
Find flight deals from Sioux Falls to Myrtle Beach
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $334 (American Airlines) |
One-way from | $309 (American Airlines) |
Popular in | November |
Cheapest in | August |
Average price | $500 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Sioux Falls to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Tue 12/8
1:08 pm-10:34 pm
1 stop8h 26m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$309
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Tue 12/8
4:37 pm-12:14 pm
3 stops42h 37m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$314
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Wed 11/25
3:18 pm-11:54 pm
2 stops7h 36m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$314
Quickest round-trip
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Sun 10/4
7:50 am-3:10 pm
1 stop6h 20m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$319
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Sun 10/4
12:16 pm-9:55 am
3 stops44h 39m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$371
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Wed 11/25
5:54 pm-8:45 am
3 stops37h 51m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$433
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Sat 1/9
7:40 am-4:49 pm
2 stops8h 09m
Myrtle Beach Intl
Tue 1/12
11:28 am-10:23 pm
2 stops11h 55m
$503
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Sun 10/4
8:23 am-6:01 pm
2 stops8h 38m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$515
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Mon 9/28
5:30 am-1:33 pm
1 stop7h 03m
Myrtle Beach Intl
Sat 10/3
3:56 pm-7:47 pm
1 stop4h 51m
$559
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Wed 11/11
7:48 am-10:21 am
3 stops25h 33m
Myrtle Beach Intl
Sat 11/14
11:27 am-9:37 pm
2 stops11h 10m
$676
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to Myrtle Beach
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Myrtle Beach in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-Myrtle Beach flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Myrtle Beach flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Myrtle Beach flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-Myrtle Beach flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Sioux Falls with our price prediction graph.
FSD-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Myrtle Beach
Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated September 7, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Sioux Falls to Myrtle Beach. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Pawleys Island
Sunset Beach
Surfside Beach
Garden City Beach
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Complete your trip
Complete your trip to Myrtle Beach by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Myrtle Beach
Explore flights to Myrtle Beach departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Sioux Falls and Myrtle Beach flights
Browse other Sioux Falls and Myrtle Beach flight options. Last updated on September 7, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Sioux Falls to Myrtle Beach
Discover the top 2 airlines that operate flights from Sioux Falls to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$308 | Average$509 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$324 | Average$601 | FlexibilityNo cancel fee | On-time71% |