$123+ Cheap flights from Sioux Falls (FSD) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — CHS
Sep 5 — Sep 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Sioux Falls to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Sioux Falls to South CarolinaExplore the most affordable flight options available from Sioux Falls to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
Explore the most affordable flight options available from Sioux Falls to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:30 am -
1 stop6h 37m
Sat 9/265:34 pm -
1 stop6h 17m
Deal found 8/3![Delta logo]()
$315
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:00 am -
1 stop4h 55m
Wed 10/215:29 pm -
1 stop6h 53m
Deal found 8/5![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:30 am -
1 stop7h 00m
Sun 9/136:20 am -
1 stop4h 59m
Deal found 8/6![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop7h 24m
Sun 11/87:11 am -
1 stop5h 33m
Deal found 8/3![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:26 pm -
2 stops7h 17m
Thu 9/105:22 pm -
1 stop6h 29m
Deal found 8/6![Delta logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:30 am -
1 stop7h 07m
Sun 9/64:20 pm -
2 stops9h 05m
Deal found 8/5![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:47 am -
2 stops10h 09m
Sat 9/265:31 pm -
1 stop6h 40m
Deal found 8/3![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:57 pm -
1 stop7h 33m
Sun 9/66:24 pm -
1 stop7h 01m
Deal found 8/6![American Airlines logo]()
$336
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:30 am -
2 stops12h 29m
Mon 8/315:15 pm -
2 stops8h 15m
Deal found 8/3![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:30 am -
1 stop6h 57m
Tue 9/155:29 pm -
1 stop6h 22m
Deal found 8/4![Delta logo]()
$340
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:30 am -
1 stop6h 22m
Thu 9/103:11 pm -
1 stop7h 37m
Deal found 8/3![American Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:28 pm -
1 stop6h 09m
Fri 9/115:13 pm -
1 stop6h 38m
Deal found 8/3![Delta logo]()
$343
Best flights from Sioux Falls to South CarolinaDiscover carefully curated flight deals from Sioux Falls to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
Discover carefully curated flight deals from Sioux Falls to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:40 am -
2 stops9h 26m
Sat 1/96:05 am -
1 stop5h 27m
Deal found 8/2![United Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/261:08 pm -
1 stop7h 07m
Wed 12/25:20 am -
1 stop8h 02m
Deal found 8/6![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:15 am -
2 stops6h 56m
Thu 9/105:22 pm -
1 stop6h 29m
Deal found 8/3![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:06 pm -
1 stop5h 13m
Thu 9/104:23 pm -
1 stop7h 49m
Deal found 8/6![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop7h 24m
Sun 11/87:11 am -
1 stop5h 33m
Deal found 8/3![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:30 am -
1 stop6h 57m
Tue 9/155:29 pm -
1 stop6h 22m
Deal found 8/4![Delta logo]()
$340
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/247:40 am -
1 stop5h 53m
Sat 1/303:20 pm -
1 stop7h 23m
Deal found 8/5![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/247:03 am -
2 stops8h 56m
Sat 1/308:00 am -
2 stops12h 05m
Deal found 8/5![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:30 am -
1 stop5h 10m
Wed 9/95:22 pm -
1 stop6h 29m
Deal found 8/5![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:55 am -
1 stop8h 27m
Tue 12/110:40 am -
1 stop4h 55m
Deal found 8/2![United Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:33 pm -
1 stop6h 42m
Sat 9/268:46 am -
1 stop8h 37m
Deal found 8/3![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2112:12 pm -
1 stop6h 52m
Mon 8/245:45 am -
1 stop7h 32m
Deal found 8/6![American Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/188:28 am -
1 stop4h 53m
Mon 12/216:55 pm -
1 stop4h 56m
Deal found 8/1![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:20 pm -
1 stop7h 09m
Sat 10/311:00 pm -
1 stop5h 58m
Deal found 8/1![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:06 pm -
2 stops9h 32m
Sun 9/64:20 pm -
2 stops9h 05m
Deal found 8/1![American Airlines logo]()
$385
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:12 am -
1 stop7h 28m
Tue 9/153:15 pm -
2 stops8h 57m
Deal found 8/4![United Airlines logo]()
$350
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:30 am -
1 stop6h 44m
Sun 10/181:59 pm -
1 stop6h 56m
Deal found 8/3![Delta logo]()
$439
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:30 am -
1 stop6h 58m
Mon 9/75:40 pm -
2 stops7h 50m
Deal found 8/3![American Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/303:16 pm -
1 stop4h 48m
Wed 2/33:19 pm -
1 stop7h 24m
Deal found 8/5![United Airlines logo]()
$391
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/303:16 pm -
1 stop5h 02m
Wed 2/34:59 pm -
1 stop5h 44m
Deal found 8/4![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:54 pm -
2 stops18h 31m
Fri 11/65:54 pm -
2 stops18h 50m
Deal found 8/3![American Airlines logo]()
$537
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:00 am -
1 stop8h 07m
Wed 1/134:15 pm -
1 stop7h 41m
Deal found 8/5![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/303:16 pm -
1 stop5h 00m
Wed 2/35:25 pm -
1 stop5h 18m
Deal found 8/1![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:40 am -
1 stop5h 02m
Wed 11/183:30 pm -
1 stop7h 07m
Deal found 8/2![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:47 am -
1 stop5h 16m
Wed 9/21:50 pm -
2 stops10h 32m
Deal found 8/2![United Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:47 am -
1 stop6h 06m
Sun 9/66:25 pm -
1 stop5h 57m
Deal found 8/1![United Airlines logo]()
$461
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:40 am -
2 stops8h 31m
Wed 11/1811:27 am -
2 stops11h 10m
Deal found 8/2![United Airlines logo]()
$472
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:30 am -
1 stop6h 58m
Thu 8/206:50 am -
1 stop6h 27m
Deal found 8/3![American Airlines logo]()
$943
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:47 am -
1 stop6h 06m
Mon 8/316:21 pm -
1 stop6h 01m
Deal found 8/1![United Airlines logo]()
$474
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:06 pm -
1 stop5h 22m
Sat 9/55:38 pm -
1 stop6h 44m
Deal found 8/5![United Airlines logo]()
$492
Last-minute flights from Sioux Falls to South CarolinaDiscover last-minute flight deals from Sioux Falls to South Carolina. Data last updated August 6, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to South Carolina. Data last updated August 6, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:30 am -
2 stops12h 29m
Mon 8/315:15 pm -
2 stops8h 15m
Deal found 8/3![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:30 am -
1 stop7h 07m
Sun 9/64:20 pm -
2 stops9h 05m
Deal found 8/5![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:57 pm -
1 stop7h 33m
Sun 9/66:24 pm -
1 stop7h 01m
Deal found 8/6![American Airlines logo]()
$336
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:28 pm -
1 stop6h 09m
Fri 9/115:13 pm -
1 stop6h 38m
Deal found 8/3![Delta logo]()
$343
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:06 pm -
1 stop5h 13m
Thu 9/104:23 pm -
1 stop7h 49m
Deal found 8/6![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:26 pm -
2 stops7h 17m
Thu 9/105:22 pm -
1 stop6h 29m
Deal found 8/6![Delta logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:30 am -
1 stop6h 22m
Thu 9/103:11 pm -
1 stop7h 37m
Deal found 8/3![American Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:30 am -
1 stop6h 57m
Tue 9/155:29 pm -
1 stop6h 22m
Deal found 8/4![Delta logo]()
$340
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:30 am -
1 stop7h 00m
Sun 9/136:20 am -
1 stop4h 59m
Deal found 8/6![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:47 am -
2 stops10h 09m
Sat 9/265:31 pm -
1 stop6h 40m
Deal found 8/3![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:30 am -
1 stop6h 37m
Sat 9/265:34 pm -
1 stop6h 17m
Deal found 8/3![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:56 pm -
1 stop8h 13m
Sun 10/47:00 am -
1 stop6h 16m
Deal found 8/3![American Airlines logo]()
$348
One-way flights from Sioux Falls to South CarolinaSearch for one-way flight options from Sioux Falls to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
Search for one-way flight options from Sioux Falls to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
This CheapOair deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:48 pm -
1 stop20h 58m
Deal found 8/2![Frontier logo]()
$123
This Expedia deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:56 pm -
1 stop18h 30m
Deal found 8/3![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:58 am -
2 stops21h 07m
Deal found 8/1![Multiple Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:28 am -
2 stops20h 33m
Deal found 8/3![Multiple Airlines logo]()
$213
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:40 am -
1 stop4h 47m
Deal found 8/1![Delta logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:31 pm -
2 stops11h 56m
Deal found 8/5![Frontier logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:02 pm -
3 stops41h 13m
Deal found 8/1![Multiple Airlines logo]()
$288
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:00 am -
2 stops13h 56m
Deal found 8/1![American Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/278:23 am -
1 stop7h 04m
Deal found 8/6![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:47 am -
1 stop6h 06m
Deal found 8/1![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:30 am -
1 stop8h 29m
Deal found 8/5![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:47 am -
2 stops10h 05m
Deal found 8/2![United Airlines logo]()
$314
Find flight deals from Sioux Falls to South Carolina
Keep the following information in mind while searching for Sioux Falls to South Carolina flight deals. Data was last updated August 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $301 (Delta) |
One-way from | $123 (CheapOair) |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Sioux Falls to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsCharleston
FSD Sioux Falls Joe Foss Field - CHS Charleston
FSDCHS
Sioux Falls Joe Foss Field
Wed 1/6
7:40 am-6:06 pm
2 stops9h 26m
Charleston
Sat 1/9
6:05 am-10:32 am
1 stop5h 27m
$306
Sioux FallsCharlotte
FSD Sioux Falls Joe Foss Field - CLT Charlotte Douglas
FSDCLT
Sioux Falls Joe Foss Field
Thu 11/26
1:08 pm-9:15 pm
1 stop7h 07m
Charlotte Douglas
Wed 12/2
5:20 am-12:22 pm
1 stop8h 02m
$329
Sioux FallsSavannah
FSD Sioux Falls Joe Foss Field - SAV Savannah/Hilton Head
FSDSAV
Sioux Falls Joe Foss Field
Sat 9/5
3:06 pm-9:19 pm
1 stop5h 13m
Savannah/Hilton Head
Thu 9/10
4:23 pm-11:12 pm
1 stop7h 49m
$329
Sioux FallsCharleston
FSD Sioux Falls Joe Foss Field - CHS Charleston
FSDCHS
Sioux Falls Joe Foss Field
Sat 11/7
7:00 am-3:24 pm
1 stop7h 24m
Charleston
Sun 11/8
7:11 am-11:44 am
1 stop5h 33m
$329
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Sun 1/24
7:40 am-2:33 pm
1 stop5h 53m
Myrtle Beach Intl
Sat 1/30
3:20 pm-9:43 pm
1 stop7h 23m
$329
Sioux FallsCharlotte
FSD Sioux Falls Joe Foss Field - CLT Charlotte Douglas
FSDCLT
Sioux Falls Joe Foss Field
Thu 11/26
5:55 am-3:22 pm
1 stop8h 27m
Charlotte Douglas
Tue 12/1
10:40 am-2:35 pm
1 stop4h 55m
$329
Sioux FallsCharlotte
FSD Sioux Falls Joe Foss Field - CLT Charlotte Douglas
FSDCLT
Sioux Falls Joe Foss Field
Sat 9/19
1:33 pm-9:15 pm
1 stop6h 42m
Charlotte Douglas
Sat 9/26
8:46 am-4:23 pm
1 stop8h 37m
$329
Sioux FallsCharlotte
FSD Sioux Falls Joe Foss Field - CLT Charlotte Douglas
FSDCLT
Sioux Falls Joe Foss Field
Tue 10/27
1:20 pm-9:29 pm
1 stop7h 09m
Charlotte Douglas
Sat 10/31
1:00 pm-5:58 pm
1 stop5h 58m
$329
Sioux FallsSavannah
FSD Sioux Falls Joe Foss Field - SAV Savannah/Hilton Head
FSDSAV
Sioux Falls Joe Foss Field
Sat 9/5
6:15 am-2:11 pm
2 stops6h 56m
Savannah/Hilton Head
Thu 9/10
5:22 pm-10:51 pm
1 stop6h 29m
$334
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Sun 1/24
7:03 am-4:59 pm
2 stops8h 56m
Myrtle Beach Intl
Sat 1/30
8:00 am-7:05 pm
2 stops12h 05m
$339
Showing 1-10 of 47 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Sioux Falls with our price prediction graph.
FSD-CHS
FSD-SAV
FSD-CLT
FSD-MYR
FSD-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to South Carolina
FSD-USSC
FSD-CHS
FSD-SAV
FSD-CLT
FSD-MYR
What is the cheapest month to book a flight from Sioux Falls to South Carolina?
Currently, February is the cheapest month in which you can book a flight from Sioux Falls to South Carolina (average of $335). Flying from Sioux Falls to South Carolina in October is currently the most expensive (average of $602). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Sioux Falls to South Carolina?
Airfare is below average for this route at the moment.
Sioux Falls to South Carolina flights typically cost between $318 and $598 in January.The cheapest round-trip price found within the last 5 days was $301 on Delta (Jan 6-Jan 9).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 6, 2026.
Read through reviews of airlines operating flights from Sioux Falls to South Carolina, such as Delta,United Airlines, andAmerican Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Sioux Falls to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Sioux Falls to South Carolina by cabin class
Find flights from Sioux Falls to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Sioux Falls and South Carolina flights
Browse other Sioux Falls and South Carolina flight options. Last updated on August 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Sioux Falls to South Carolina flights
Consider these flights traveling from Sioux Falls to South Carolina.
Top 3 airlines flying from Sioux Falls to South Carolina
Discover the top 3 airlines that operate flights from Sioux Falls to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$250 | Average$411 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$264 | Average$479 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$308 | Average$520 | FlexibilityNo cancel fee | On-time71% |