$126+ Cheap flights from Sioux Falls (FSD) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — CHS
Sep 11 — Sep 181
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Sioux Falls to South CarolinaExplore the most affordable flight options available from Sioux Falls to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
Explore the most affordable flight options available from Sioux Falls to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop5h 05m
Tue 11/33:11 pm -
1 stop5h 21m
Deal found 8/7![Delta logo]()
$301
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:03 am -
1 stop6h 52m
Tue 11/32:40 pm -
2 stops10h 59m
Deal found 8/10![American Airlines logo]()
$306
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
2 stops7h 28m
Tue 11/33:02 pm -
2 stops7h 35m
Deal found 8/7![United Airlines logo]()
$311
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:06 pm -
1 stop5h 13m
Thu 9/104:23 pm -
1 stop7h 49m
Deal found 8/9![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:30 am -
1 stop7h 00m
Sun 9/136:20 am -
1 stop4h 59m
Deal found 8/7![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:47 am -
2 stops10h 09m
Tue 9/226:01 pm -
1 stop6h 11m
Deal found 8/10![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:30 am -
1 stop8h 29m
Sun 9/65:45 am -
1 stop7h 32m
Deal found 8/7![American Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:24 am -
2 stops11h 27m
Sun 9/66:32 pm -
2 stops6h 53m
Deal found 8/11![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:06 pm -
1 stop5h 28m
Wed 9/304:58 pm -
1 stop7h 13m
Deal found 8/11![United Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3112:06 pm -
2 stops9h 54m
Wed 9/307:18 am -
1 stop5h 18m
Deal found 8/11![American Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:00 pm -
1 stop4h 25m
Sun 10/187:04 am -
1 stop6h 05m
Deal found 8/8![Delta logo]()
$354
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:30 am -
2 stops12h 29m
Mon 8/3112:14 pm -
2 stops9h 17m
Deal found 8/10![American Airlines logo]()
$364
Best flights from Sioux Falls to South CarolinaDiscover carefully curated flight deals from Sioux Falls to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
Discover carefully curated flight deals from Sioux Falls to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop6h 30m
Tue 11/32:18 pm -
1 stop6h 37m
Deal found 8/8![Delta logo]()
$301
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:03 am -
1 stop6h 52m
Tue 11/32:40 pm -
2 stops10h 59m
Deal found 8/8![American Airlines logo]()
$306
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
2 stops7h 28m
Tue 11/33:02 pm -
2 stops7h 35m
Deal found 8/7![United Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/112:48 pm -
1 stop8h 11m
Sat 1/167:16 am -
1 stop8h 02m
Deal found 8/9![American Airlines logo]()
$315
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:06 pm -
1 stop5h 13m
Thu 9/104:23 pm -
1 stop7h 49m
Deal found 8/9![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:30 am -
1 stop7h 00m
Sun 9/136:20 am -
1 stop4h 59m
Deal found 8/8![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:00 am -
1 stop6h 16m
Mon 9/287:16 pm -
1 stop4h 35m
Deal found 8/8![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:47 am -
2 stops8h 13m
Tue 9/226:01 pm -
1 stop6h 11m
Deal found 8/10![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:28 pm -
2 stops6h 53m
Thu 9/102:55 pm -
1 stop5h 52m
Deal found 8/9![Delta logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:06 pm -
2 stops8h 50m
Sat 8/2912:07 pm -
1 stop5h 46m
Deal found 8/10![American Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:00 pm -
1 stop4h 25m
Sun 10/187:04 am -
1 stop6h 05m
Deal found 8/8![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:47 am -
1 stop5h 11m
Tue 9/224:58 pm -
1 stop7h 14m
Deal found 8/10![United Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2112:12 pm -
1 stop6h 52m
Mon 8/247:42 am -
1 stop4h 54m
Deal found 8/9![American Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:30 am -
1 stop6h 56m
Sun 9/61:57 pm -
1 stop7h 02m
Deal found 8/9![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/911:20 am -
1 stop5h 05m
Wed 1/134:59 pm -
1 stop5h 44m
Deal found 8/8![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
2 stops9h 45m
Tue 9/1512:50 pm -
2 stops7h 52m
Deal found 8/10![American Airlines logo]()
$428
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:30 am -
1 stop4h 41m
Fri 10/97:15 pm -
1 stop5h 07m
Deal found 8/6![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:47 am -
2 stops10h 48m
Sat 9/58:10 am -
1 stop7h 21m
Deal found 8/10![United Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:25 am -
2 stops10h 56m
Tue 11/174:10 pm -
1 stop4h 48m
Deal found 8/11![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:47 am -
2 stops10h 00m
Mon 8/316:21 pm -
1 stop6h 01m
Deal found 8/9![United Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:00 am -
2 stops10h 49m
Mon 9/2112:10 pm -
2 stops13h 19m
Deal found 8/11![American Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:05 am -
1 stop4h 36m
Sun 10/117:04 am -
1 stop6h 05m
Deal found 8/6![Delta logo]()
$413
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:06 pm -
1 stop5h 22m
Sun 8/306:25 am -
1 stop5h 04m
Deal found 8/11![United Airlines logo]()
$469
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:06 pm -
1 stop5h 22m
Sat 9/55:38 pm -
1 stop6h 44m
Deal found 8/6![United Airlines logo]()
$474
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:05 am -
1 stop4h 36m
Mon 10/125:30 am -
2 stops11h 30m
Deal found 8/6![Delta logo]()
$476
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:47 am -
2 stops11h 57m
Tue 9/811:23 am -
2 stops12h 49m
Deal found 8/6![United Airlines logo]()
$477
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:05 am -
2 stops11h 56m
Sat 9/263:56 pm -
1 stop4h 51m
Deal found 8/9![Delta logo]()
$489
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
2 stops10h 11m
Wed 11/411:27 am -
2 stops11h 10m
Deal found 8/11![United Airlines logo]()
$553
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:47 am -
1 stop6h 06m
Fri 9/46:21 pm -
2 stops26h 46m
Deal found 8/8![United Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:47 am -
1 stop5h 30m
Tue 9/295:00 pm -
1 stop7h 11m
Deal found 8/11![United Airlines logo]()
$593
Last-minute flights from Sioux Falls to South CarolinaDiscover last-minute flight deals from Sioux Falls to South Carolina. Data last updated August 12, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to South Carolina. Data last updated August 12, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:47 am -
1 stop6h 17m
Sat 8/294:59 pm -
1 stop7h 23m
Deal found 8/10![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:30 am -
2 stops12h 29m
Mon 8/3112:14 pm -
2 stops9h 17m
Deal found 8/10![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:06 pm -
1 stop5h 28m
Wed 9/304:58 pm -
1 stop7h 13m
Deal found 8/11![United Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3112:06 pm -
2 stops9h 54m
Wed 9/307:18 am -
1 stop5h 18m
Deal found 8/11![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:24 am -
2 stops11h 27m
Sun 9/66:32 pm -
2 stops6h 53m
Deal found 8/11![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:30 am -
1 stop8h 29m
Sun 9/65:45 am -
1 stop7h 32m
Deal found 8/7![American Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:30 am -
1 stop6h 56m
Sun 9/61:57 pm -
1 stop7h 02m
Deal found 8/9![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:06 pm -
1 stop5h 13m
Thu 9/104:23 pm -
1 stop7h 49m
Deal found 8/9![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:28 pm -
2 stops6h 53m
Thu 9/102:55 pm -
1 stop5h 52m
Deal found 8/9![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:30 am -
1 stop7h 00m
Sun 9/136:20 am -
1 stop4h 59m
Deal found 8/10![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:47 am -
2 stops10h 09m
Tue 9/226:01 pm -
1 stop6h 11m
Deal found 8/10![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:56 pm -
1 stop8h 13m
Sat 10/37:00 am -
1 stop6h 16m
Deal found 8/11![American Airlines logo]()
$329
One-way flights from Sioux Falls to South CarolinaSearch for one-way flight options from Sioux Falls to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
Search for one-way flight options from Sioux Falls to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
This CheapOair deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:48 pm -
1 stop20h 58m
Deal found 8/9![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:00 pm -
2 stops11h 59m
Deal found 8/10![Multiple Airlines logo]()
$207
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:28 pm -
1 stop6h 12m
Deal found 8/8![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:30 am -
1 stop4h 46m
Deal found 8/7![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:00 am -
2 stops6h 34m
Deal found 8/9![Delta logo]()
$314
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:47 am -
2 stops10h 09m
Deal found 8/8![United Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
2 stops12h 11m
Deal found 8/7![United Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:31 pm -
3 stops32h 56m
Deal found 8/9![Multiple Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop8h 22m
Deal found 8/9![American Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:30 am -
2 stops9h 16m
Deal found 8/9![Delta logo]()
$358
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:26 pm -
1 stop7h 28m
Deal found 8/7![American Airlines logo]()
$448
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:57 pm -
1 stop5h 47m
Deal found 8/10![American Airlines logo]()
$484
Find flight deals from Sioux Falls to South Carolina
Keep the following information in mind while searching for Sioux Falls to South Carolina flight deals. Data was last updated August 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $301 (Delta) |
One-way from | $126 (CheapOair) |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Sioux Falls to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsCharleston
FSD Sioux Falls Joe Foss Field - CHS Charleston
FSDCHS
Sioux Falls Joe Foss Field
Wed 10/28
5:30 am-1:00 pm
1 stop6h 30m
Charleston
Tue 11/3
2:18 pm-7:55 pm
1 stop6h 37m
$301
Sioux FallsCharleston
FSD Sioux Falls Joe Foss Field - CHS Charleston
FSDCHS
Sioux Falls Joe Foss Field
Wed 10/28
7:03 am-2:55 pm
1 stop6h 52m
Charleston
Tue 11/3
2:40 pm-12:39 am
2 stops10h 59m
$306
Sioux FallsCharleston
FSD Sioux Falls Joe Foss Field - CHS Charleston
FSDCHS
Sioux Falls Joe Foss Field
Wed 10/28
6:00 am-2:28 pm
2 stops7h 28m
Charleston
Tue 11/3
3:02 pm-9:37 pm
2 stops7h 35m
$311
Sioux FallsCharleston
FSD Sioux Falls Joe Foss Field - CHS Charleston
FSDCHS
Sioux Falls Joe Foss Field
Mon 1/11
2:48 pm-11:59 pm
1 stop8h 11m
Charleston
Sat 1/16
7:16 am-2:18 pm
1 stop8h 02m
$315
Sioux FallsSavannah
FSD Sioux Falls Joe Foss Field - SAV Savannah/Hilton Head
FSDSAV
Sioux Falls Joe Foss Field
Sat 9/5
3:06 pm-9:19 pm
1 stop5h 13m
Savannah/Hilton Head
Thu 9/10
4:23 pm-11:12 pm
1 stop7h 49m
$329
Sioux FallsCharlotte
FSD Sioux Falls Joe Foss Field - CLT Charlotte Douglas
FSDCLT
Sioux Falls Joe Foss Field
Wed 9/9
5:30 am-1:30 pm
1 stop7h 00m
Charlotte Douglas
Sun 9/13
6:20 am-10:19 am
1 stop4h 59m
$329
Sioux FallsCharlotte
FSD Sioux Falls Joe Foss Field - CLT Charlotte Douglas
FSDCLT
Sioux Falls Joe Foss Field
Wed 9/23
11:00 am-6:16 pm
1 stop6h 16m
Charlotte Douglas
Mon 9/28
7:16 pm-10:51 pm
1 stop4h 35m
$329
Sioux FallsCharlotte
FSD Sioux Falls Joe Foss Field - CLT Charlotte Douglas
FSDCLT
Sioux Falls Joe Foss Field
Tue 9/15
7:47 am-5:00 pm
2 stops8h 13m
Charlotte Douglas
Tue 9/22
6:01 pm-11:12 pm
1 stop6h 11m
$334
Sioux FallsSavannah
FSD Sioux Falls Joe Foss Field - SAV Savannah/Hilton Head
FSDSAV
Sioux Falls Joe Foss Field
Sat 9/5
4:28 pm-12:21 am
2 stops6h 53m
Savannah/Hilton Head
Thu 9/10
2:55 pm-7:47 pm
1 stop5h 52m
$334
Sioux FallsCharlotte
FSD Sioux Falls Joe Foss Field - CLT Charlotte Douglas
FSDCLT
Sioux Falls Joe Foss Field
Thu 10/15
1:00 pm-6:25 pm
1 stop4h 25m
Charlotte Douglas
Sun 10/18
7:04 am-12:09 pm
1 stop6h 05m
$354
Showing 1-10 of 45 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Sioux Falls with our price prediction graph.
FSD-SAV
FSD-CAE
FSD-CLT
FSD-MYR
FSD-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to South Carolina
FSD-USSC
FSD-SAV
FSD-CAE
FSD-CLT
FSD-MYR
What is the cheapest month to book a flight from Sioux Falls to South Carolina?
Currently, February is the cheapest month in which you can book a flight from Sioux Falls to South Carolina (average of $335). Flying from Sioux Falls to South Carolina in October is currently the most expensive (average of $602). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Sioux Falls to South Carolina?
Airfare is below average for this route at the moment.
Sioux Falls to South Carolina flights typically cost between $318 and $598 in October.The cheapest round-trip price found within the last 5 days was $301 on Delta (Oct 28-Nov 3).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 12, 2026.
Read through reviews of airlines operating flights from Sioux Falls to South Carolina, such as Delta,United Airlines, andAmerican Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Sioux Falls to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Sioux Falls and South Carolina flights
Browse other Sioux Falls and South Carolina flight options. Last updated on August 12, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Sioux Falls to South Carolina flights
Consider these flights traveling from Sioux Falls to South Carolina.
Top 3 airlines flying from Sioux Falls to South Carolina
Discover the top 3 airlines that operate flights from Sioux Falls to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$250 | Average$411 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$264 | Average$479 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$308 | Average$520 | FlexibilityNo cancel fee | On-time71% |