$211+ Cheap flights from South Carolina to Sioux Falls (FSD)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — FSD
Oct 27 — Nov 31
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from South Carolina to Sioux Falls with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Sioux Falls
Cheapest
Best
Last-minute
One-way
Cheapest flights from South Carolina to Sioux FallsExplore the most affordable flight options available from South Carolina to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 27, 2026.
Explore the most affordable flight options available from South Carolina to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 27, 2026.
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:01 am -
1 stop6h 38m
Sat 10/3112:53 pm -
1 stop8h 12m
Deal found 9/23![American Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:51 pm -
2 stops9h 20m
Sat 10/316:00 am -
1 stop6h 21m
Deal found 9/23![United Airlines logo]()
$326
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:40 am -
1 stop8h 08m
Mon 11/167:00 am -
1 stop8h 07m
Deal found 9/24![American Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:20 am -
2 stops13h 36m
Mon 11/168:31 am -
2 stops10h 30m
Deal found 9/24![Delta logo]()
$345
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:38 pm -
1 stop6h 33m
Sat 10/313:10 pm -
1 stop4h 52m
Deal found 9/26![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:50 pm -
1 stop5h 21m
Fri 10/2311:35 am -
1 stop9h 11m
Deal found 9/24![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:00 pm -
1 stop6h 55m
Sat 11/711:00 am -
2 stops8h 21m
Deal found 9/25![Delta logo]()
$395
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:43 pm -
1 stop6h 58m
Sat 10/1012:53 pm -
1 stop8h 12m
Deal found 9/23![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:16 am -
1 stop8h 02m
Tue 10/1312:53 pm -
1 stop8h 40m
Deal found 9/24![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:01 am -
1 stop6h 38m
Sat 11/71:08 pm -
1 stop7h 50m
Deal found 9/25![American Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:20 am -
1 stop5h 12m
Sat 10/315:55 am -
1 stop8h 08m
Deal found 9/22![United Airlines logo]()
$421
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:34 pm -
2 stops9h 14m
Sun 10/187:05 am -
1 stop6h 57m
Deal found 9/24![American Airlines logo]()
$424
Best flights from South Carolina to Sioux FallsDiscover carefully curated flight deals from South Carolina to Sioux Falls that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 27, 2026.
Discover carefully curated flight deals from South Carolina to Sioux Falls that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 27, 2026.
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:01 am -
1 stop6h 38m
Sat 10/3112:53 pm -
1 stop8h 12m
Deal found 9/23![American Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:51 pm -
2 stops9h 20m
Sat 10/316:00 am -
1 stop6h 21m
Deal found 9/23![United Airlines logo]()
$326
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/111:44 am -
1 stop8h 19m
Wed 1/131:23 pm -
1 stop7h 47m
Deal found 9/26![American Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:38 pm -
1 stop6h 33m
Sat 10/313:10 pm -
1 stop4h 52m
Deal found 9/26![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1410:52 am -
2 stops8h 56m
Mon 11/163:26 pm -
1 stop5h 33m
Deal found 9/24![American Airlines logo]()
$340
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:50 pm -
1 stop5h 21m
Fri 10/2311:35 am -
1 stop9h 11m
Deal found 9/24![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:16 am -
1 stop8h 02m
Tue 10/1312:53 pm -
1 stop8h 40m
Deal found 9/24![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:20 am -
1 stop5h 12m
Sat 10/315:55 am -
1 stop8h 08m
Deal found 9/22![United Airlines logo]()
$421
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:01 am -
1 stop6h 38m
Sat 11/71:08 pm -
1 stop7h 50m
Deal found 9/25![American Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:00 am -
1 stop5h 40m
Sat 1/97:40 am -
1 stop5h 11m
Deal found 9/21![United Airlines logo]()
$431
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:00 pm -
1 stop7h 11m
Mon 10/127:50 am -
1 stop6h 26m
Deal found 9/23![United Airlines logo]()
$436
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:13 pm -
1 stop8h 31m
Tue 10/133:03 pm -
2 stops8h 12m
Deal found 9/24![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:38 pm -
1 stop6h 33m
Tue 10/1311:15 am -
1 stop4h 42m
Deal found 9/24![United Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:00 am -
1 stop6h 13m
Wed 10/1412:53 pm -
1 stop8h 59m
Deal found 9/25![American Airlines logo]()
$672
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:37 pm -
1 stop5h 01m
Fri 11/69:32 am -
2 stops30h 28m
Deal found 9/22![United Airlines logo]()
$709
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:30 pm -
2 stops11h 41m
Wed 10/147:50 am -
2 stops24h 52m
Deal found 9/25![United Airlines logo]()
$804
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:15 am -
1 stop5h 14m
Tue 10/2011:15 am -
1 stop4h 42m
Deal found 9/23![United Airlines logo]()
$1,063
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:22 am -
1 stop5h 06m
Tue 10/2011:15 am -
1 stop4h 42m
Deal found 9/26![United Airlines logo]()
$1,410
Last-minute flights from South Carolina to Sioux FallsDiscover last-minute flight deals from South Carolina to Sioux Falls. Data last updated September 27, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Sioux Falls. Data last updated September 27, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:43 pm -
1 stop6h 58m
Sat 10/1012:53 pm -
1 stop8h 12m
Deal found 9/23![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:05 am -
2 stops9h 50m
Sat 10/1011:00 am -
2 stops10h 51m
Deal found 9/23![Delta logo]()
$439
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:00 pm -
1 stop7h 11m
Mon 10/127:50 am -
1 stop6h 26m
Deal found 9/23![United Airlines logo]()
$436
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:50 pm -
1 stop5h 21m
Fri 10/2311:35 am -
1 stop9h 11m
Deal found 9/24![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:16 am -
1 stop8h 02m
Tue 10/1312:53 pm -
1 stop8h 40m
Deal found 9/24![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:34 pm -
2 stops9h 14m
Sun 10/187:05 am -
1 stop6h 57m
Deal found 9/24![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:01 am -
1 stop6h 38m
Sat 10/3112:53 pm -
1 stop8h 12m
Deal found 9/23![American Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:51 pm -
2 stops9h 20m
Sat 10/316:00 am -
1 stop6h 21m
Deal found 9/23![United Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:38 pm -
1 stop6h 33m
Sat 10/313:10 pm -
1 stop4h 52m
Deal found 9/26![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:20 am -
1 stop5h 12m
Sat 10/315:55 am -
1 stop8h 08m
Deal found 9/22![United Airlines logo]()
$421
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:00 pm -
1 stop6h 55m
Sat 11/711:00 am -
2 stops8h 21m
Deal found 9/25![Delta logo]()
$395
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:01 am -
1 stop6h 38m
Sat 11/71:08 pm -
1 stop7h 50m
Deal found 9/25![American Airlines logo]()
$420
One-way flights from South Carolina to Sioux FallsSearch for one-way flight options from South Carolina to Sioux Falls. Find affordable one-way fares based on user searches. Data last updated September 27, 2026.
Search for one-way flight options from South Carolina to Sioux Falls. Find affordable one-way fares based on user searches. Data last updated September 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:18 am -
1 stop10h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Allegiant Air logo]()
$211
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/205:30 pm -
1 stop6h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/205:10 am -
2 stops10h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:29 pm -
1 stop8h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![United Airlines logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:04 pm -
3 stops21h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$373
This Alaska Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/201:07 pm -
3 stops30h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Alaska Airlines logo]()
$582
Find flight deals from South Carolina to Sioux Falls
Keep the following information in mind while searching for South Carolina to Sioux Falls flight deals. Data was last updated September 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $321 (American Airlines) |
One-way from | $211 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $552 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 27, 2026.
Use the filters below to find and compare flights from South Carolina to Sioux Falls that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSioux Falls
GSP Greenville - FSD Sioux Falls Joe Foss Field
GSPFSD
Greenville
Sun 11/8
9:18 am-6:24 pm
1 stop10h 06m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$211
Quickest round-trip
CharlestonSioux Falls
CHS Charleston - FSD Sioux Falls Joe Foss Field
CHSFSD
Charleston
Sat 2/20
5:30 pm-10:51 pm
1 stop6h 21m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$319
GreenvilleSioux Falls
GSP Greenville - FSD Sioux Falls Joe Foss Field
GSPFSD
Greenville
Sat 10/24
6:01 am-11:39 am
1 stop6h 38m
Sioux Falls Joe Foss Field
Sat 10/31
12:53 pm-10:05 pm
1 stop8h 12m
$321
CharlestonSioux Falls
CHS Charleston - FSD Sioux Falls Joe Foss Field
CHSFSD
Charleston
Sat 2/20
5:10 am-2:18 pm
2 stops10h 08m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$324
GreenvilleSioux Falls
GSP Greenville - FSD Sioux Falls Joe Foss Field
GSPFSD
Greenville
Sat 10/24
2:51 pm-11:11 pm
2 stops9h 20m
Sioux Falls Joe Foss Field
Sat 10/31
6:00 am-1:21 pm
1 stop6h 21m
$326
GreenvilleSioux Falls
GSP Greenville - FSD Sioux Falls Joe Foss Field
GSPFSD
Greenville
Fri 1/1
11:44 am-7:03 pm
1 stop8h 19m
Sioux Falls Joe Foss Field
Wed 1/13
1:23 pm-10:10 pm
1 stop7h 47m
$335
GreenvilleSioux Falls
GSP Greenville - FSD Sioux Falls Joe Foss Field
GSPFSD
Greenville
Sat 11/14
10:52 am-6:48 pm
2 stops8h 56m
Sioux Falls Joe Foss Field
Mon 11/16
3:26 pm-9:59 pm
1 stop5h 33m
$340
ColumbiaSioux Falls
CAE Columbia Metropolitan - FSD Sioux Falls Joe Foss Field
CAEFSD
Columbia Metropolitan
Sat 10/24
5:38 pm-11:11 pm
1 stop6h 33m
Sioux Falls Joe Foss Field
Sat 10/31
3:10 pm-9:02 pm
1 stop4h 52m
$349
GreenvilleSioux Falls
GSP Greenville - FSD Sioux Falls Joe Foss Field
GSPFSD
Greenville
Sun 11/8
4:29 pm-11:44 pm
1 stop8h 15m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$350
GreenvilleSioux Falls
GSP Greenville - FSD Sioux Falls Joe Foss Field
GSPFSD
Greenville
Sun 11/8
8:04 pm-4:44 pm
3 stops21h 40m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$373
Showing 1-10 of 24 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Sioux Falls
Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from South Carolina with our price prediction graph.
GSP-FSD
CAE-FSD
CHS-FSD
MYR-FSD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Sioux Falls
USSC-FSD
GSP-FSD
CAE-FSD
CHS-FSD
MYR-FSD
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Sioux Falls?
Book flights to Sioux Falls if you plan to visit one of these locationsYankton
Marshall
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Sioux Falls flight routes
Top destinations
Alternative routes for South Carolina to Sioux Falls
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Sioux Falls by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Sioux Falls by cabin class
Find flights from South Carolina to Sioux Falls, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Sioux Falls flights
Browse other South Carolina and Sioux Falls flight options. Last updated on September 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Sioux Falls
Explore flights to Sioux Falls departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 27, 2026.
South Carolina to Sioux Falls flights
Consider these flights traveling from South Carolina to Sioux Falls.
Top airline flying from South Carolina to Sioux Falls
Discover the top airline that operate flights from South Carolina to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$269 | Average$480 | FlexibilityNo cancel fee | On-time71% |