$319+ Cheap flights from Sioux Falls to Louisville (FSD - SDF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — SDF
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to Louisville
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Best
Last-minute
Cheapest flights from Sioux Falls to LouisvilleExplore the most affordable flight options available from Sioux Falls to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Sioux Falls to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:53 pm -
1 stop7h 32m
Mon 10/264:18 pm -
1 stop5h 55m
Deal found 9/8![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2511:00 am -
1 stop6h 11m
Sat 1/26:30 am -
1 stop6h 28m
Deal found 9/8![Delta logo]()
$373
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:56 pm -
1 stop7h 35m
Tue 9/225:59 pm -
1 stop7h 30m
Deal found 9/5![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:20 pm -
1 stop8h 04m
Sun 11/13:24 pm -
1 stop5h 40m
Deal found 9/8![United Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:53 pm -
1 stop7h 32m
Mon 10/196:00 am -
1 stop7h 13m
Deal found 9/8![American Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:23 am -
1 stop6h 26m
Tue 9/227:54 pm -
1 stop3h 57m
Deal found 9/9![Delta logo]()
$409
Best flights from Sioux Falls to LouisvilleDiscover carefully curated flight deals from Sioux Falls to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Sioux Falls to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:20 pm -
1 stop8h 04m
Sun 11/13:24 pm -
1 stop5h 40m
Deal found 9/9![United Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:00 pm -
1 stop4h 51m
Sun 11/87:00 am -
1 stop4h 00m
Deal found 9/6![Delta logo]()
$435
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:53 pm -
1 stop7h 32m
Sun 10/2510:16 am -
1 stop15h 25m
Deal found 9/7![American Airlines logo]()
$466
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:40 am -
1 stop4h 40m
Sat 1/92:08 pm -
1 stop5h 25m
Deal found 9/8![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:13 pm -
2 stops10h 07m
Sat 1/210:31 am -
1 stop4h 17m
Deal found 9/5![American Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:53 pm -
1 stop7h 32m
Sun 10/1812:46 pm -
1 stop12h 55m
Deal found 9/5![American Airlines logo]()
$608
Last-minute flights from Sioux Falls to LouisvilleDiscover last-minute flight deals from Sioux Falls to Louisville. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Louisville. Data last updated September 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:56 pm -
1 stop7h 35m
Tue 9/225:59 pm -
1 stop7h 30m
Deal found 9/5![American Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:23 am -
1 stop6h 26m
Tue 9/227:54 pm -
1 stop3h 57m
Deal found 9/9![Delta logo]()
$409
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:53 pm -
1 stop7h 32m
Mon 10/196:00 am -
1 stop7h 13m
Deal found 9/8![American Airlines logo]()
$396
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:53 pm -
1 stop7h 32m
Mon 10/264:18 pm -
1 stop5h 55m
Deal found 9/8![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:20 pm -
1 stop8h 04m
Sun 11/13:24 pm -
1 stop5h 40m
Deal found 9/8![United Airlines logo]()
$386
Find flight deals from Sioux Falls to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (American Airlines) |
Popular in | March |
Cheapest in | June |
Average price | $332 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Sioux Falls to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsLouisville
FSD Sioux Falls Joe Foss Field - SDF Louisville Intl
FSDSDF
Sioux Falls Joe Foss Field
Thu 10/29
1:20 pm-10:24 pm
1 stop8h 04m
Louisville Intl
Sun 11/1
3:24 pm-8:04 pm
1 stop5h 40m
$388
Sioux FallsLouisville
FSD Sioux Falls Joe Foss Field - SDF Louisville Intl
FSDSDF
Sioux Falls Joe Foss Field
Wed 1/6
7:40 am-1:20 pm
1 stop4h 40m
Louisville Intl
Sat 1/9
2:08 pm-6:33 pm
1 stop5h 25m
$399
Quickest round-trip
Sioux FallsLouisville
FSD Sioux Falls Joe Foss Field - SDF Louisville Intl
FSDSDF
Sioux Falls Joe Foss Field
Fri 11/6
5:00 pm-10:51 pm
1 stop4h 51m
Louisville Intl
Sun 11/8
7:00 am-10:00 am
1 stop4h 00m
$435
Sioux FallsLouisville
FSD Sioux Falls Joe Foss Field - SDF Louisville Intl
FSDSDF
Sioux Falls Joe Foss Field
Fri 10/23
12:53 pm-9:25 pm
1 stop7h 32m
Louisville Intl
Sun 10/25
10:16 am-12:41 am
1 stop15h 25m
$466
Sioux FallsLouisville
FSD Sioux Falls Joe Foss Field - SDF Louisville Intl
FSDSDF
Sioux Falls Joe Foss Field
Wed 11/25
1:13 pm-12:20 am
2 stops10h 07m
Louisville Intl
Sat 1/2
10:31 am-1:48 pm
1 stop4h 17m
$517
Sioux FallsLouisville
FSD Sioux Falls Joe Foss Field - SDF Louisville Intl
FSDSDF
Sioux Falls Joe Foss Field
Fri 10/16
12:53 pm-9:25 pm
1 stop7h 32m
Louisville Intl
Sun 10/18
12:46 pm-12:41 am
1 stop12h 55m
$608
Sorted by cheapest first
Compare providers for flights from Sioux Falls to Louisville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Louisville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Sioux Falls with our price prediction graph.
FSD-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Louisville
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated September 9, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Jeffersonville
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Other flights to Louisville
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Sioux Falls and Louisville flights
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Other flights from Sioux Falls
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Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Sioux Falls to Louisville
Discover the top 3 airlines that operate flights from Sioux Falls to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$293 | Average$388 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$310 | Average$413 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$328 | Average$383 | FlexibilityNo cancel fee | On-time71% |