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$279+ Cheap flights from Sioux Falls to Louisville (FSD - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — SDF
May 27 — Jun 31
Wed 5/27
Wed 6/3
1 adult, Economy
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Cheap flight deals from Sioux Falls to Louisville

Cheapest flights from Sioux Falls to Louisville
Explore the most affordable flight options available from Sioux Falls to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.

This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:20 pm
FSD
-
SDF
1 stop4h 23m
Delta
Tue 9/225:45 pm
SDF
-
FSD
1 stop5h 24m
Delta
Deal found 4/24$311
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:25 pm
FSD
-
SDF
1 stop5h 20m
American Airlines
Tue 9/223:54 pm
SDF
-
FSD
2 stops8h 57m
American Airlines
Deal found 4/27$316
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:16 pm
FSD
-
SDF
1 stop6h 36m
Delta
Mon 6/17:49 pm
SDF
-
FSD
1 stop4h 22m
Delta
Deal found 4/26$320
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:29 pm
FSD
-
SDF
1 stop5h 02m
American Airlines
Wed 5/205:56 am
SDF
-
FSD
1 stop7h 03m
American Airlines
Deal found 4/22$329
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:19 am
FSD
-
SDF
1 stop6h 29m
Delta
Sun 5/174:28 pm
SDF
-
FSD
1 stop3h 59m
Delta
Deal found 4/24$334
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:16 pm
FSD
-
SDF
1 stop6h 36m
Delta
Mon 5/117:49 pm
SDF
-
FSD
1 stop4h 22m
Delta
Deal found 4/23$339
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/94:17 pm
FSD
-
SDF
1 stop6h 35m
Delta
Tue 5/126:00 am
SDF
-
FSD
2 stops7h 49m
Delta
Deal found 4/22$344
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:16 pm
FSD
-
SDF
1 stop6h 36m
Delta
Mon 5/256:05 am
SDF
-
FSD
1 stop5h 10m
Delta
Deal found 4/27$364

Find flight deals from Sioux Falls to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$320
(Delta)

One-way from

$279
(Delta)

Popular in

March

Cheapest in

September

Average price

$431
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Louisville Intl flights.
Search Deals
From Sioux Falls Joe Foss Field to Louisville Intl
Search Deals
One-way flight from Sioux Falls Joe Foss Field to Louisville Intl
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($89 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from Sioux Falls to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsLouisville

FSD - SDF

FSDSDF

Sioux Falls Joe Foss Field

Fri 5/29

4:16 pm-11:52 pm

1 stop6h 36m

Louisville Intl

Mon 6/1

7:49 pm-11:11 pm

1 stop4h 22m

$320

Sioux FallsLouisville

FSD - SDF

FSDSDF

Sioux Falls Joe Foss Field

Sat 5/16

12:29 pm-6:31 pm

1 stop5h 02m

Louisville Intl

Wed 5/20

5:56 am-11:59 am

1 stop7h 03m

$329
Quickest round-trip

Sioux FallsLouisville

FSD - SDF

FSDSDF

Sioux Falls Joe Foss Field

Sat 5/9

6:50 am-11:59 am

1 stop4h 09m

Louisville Intl

Tue 5/12

12:42 pm-3:36 pm

1 stop3h 54m

$339

Sioux FallsLouisville

FSD - SDF

FSDSDF

Sioux Falls Joe Foss Field

Thu 5/7

4:16 pm-11:52 pm

1 stop6h 36m

Louisville Intl

Mon 5/11

7:49 pm-11:11 pm

1 stop4h 22m

$339

Sioux FallsLouisville

FSD - SDF

FSDSDF

Sioux Falls Joe Foss Field

Sat 5/9

6:50 am-11:59 am

1 stop4h 09m

Louisville Intl

Wed 5/13

2:34 pm-7:27 pm

2 stops5h 53m

$344

Sioux FallsLouisville

FSD - SDF

FSDSDF

Sioux Falls Joe Foss Field

Fri 5/22

4:16 pm-11:52 pm

1 stop6h 36m

Louisville Intl

Mon 5/25

6:05 am-10:15 am

1 stop5h 10m

$364

Sioux FallsLouisville

FSD - SDF

FSDSDF

Sioux Falls Joe Foss Field

Thu 5/21

1:35 pm-12:25 am

2 stops9h 50m

Louisville Intl

Mon 5/25

6:05 am-10:15 am

1 stop5h 10m

$484

Sioux FallsLouisville

FSD - SDF

FSDSDF

Sioux Falls Joe Foss Field

Thu 5/14

1:35 pm-9:18 pm

2 stops6h 43m

Louisville Intl

Sun 5/17

6:00 am-12:49 pm

2 stops7h 49m

$509

Sioux FallsLouisville

FSD - SDF

FSDSDF

Sioux Falls Joe Foss Field

Thu 5/7

1:41 pm-12:25 am

2 stops9h 44m

Louisville Intl

Mon 5/11

7:01 pm-11:06 pm

1 stop5h 05m

$536
Cheapest one-way
Quickest one-way

Sioux FallsLouisville

FSD - SDF

FSDSDF

Sioux Falls Joe Foss Field

Tue 9/15

5:25 am-11:33 am

1 stop5h 08m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Sorted by cheapest first

Compare providers for flights from Sioux Falls to Louisville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Louisville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Sioux Falls-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Louisville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Sioux Falls-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Sioux Falls to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Louisville

What is the cheapest month to book a flight from Sioux Falls to Louisville?

Currently, September is the cheapest month in which you can book a flight from Sioux Falls to Louisville (average of $258). Flying from Sioux Falls to Louisville in March is currently the most expensive (average of $488). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Sioux Falls to Louisville?

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated April 27, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,463 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,463 reviews
Delta
7.9
Good
8,463 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,665 reviews
Delta
7.9
Good
8,463 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,668 reviews
Delta
7.9
Good
8,463 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Sioux Falls to Louisville?

    Departing from Sioux Falls to Louisville will take you 5h 02m. Sioux Falls and Louisville are separated by a distance of 684 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Sioux Falls to Louisville round-trip?

    Currently priced at $174, United Airlines will fly you from Sioux Falls to Louisville and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Delta - these airlines can fly you to your destination from $248 and $269, respectively. United Airlines is currently priced 53% below the average price you’ll pay for this route.

  • Can I find deals for flights from Sioux Falls to Louisville that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Louisville.

  • Can I find deals for business class flights from Sioux Falls to Louisville?

    Yes. Cheapflights offers flight deals from Sioux Falls to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Louisville?

    Currently, September is the cheapest month in which you can book a flight from Sioux Falls to Louisville (average of $258). Flying from Sioux Falls to Louisville in March is currently the most expensive (average of $488). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Elizabethtown
Corydon
Jeffersonville
Bardstown

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Sioux Falls to Louisville

Discover the top 3 airlines that operate flights from Sioux Falls to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$174Average$413FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$352FlexibilityNo cancel feeOn-time71%
DeltaCheapest$269Average$338FlexibilityNo cancel feeOn-timeN/A

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