$252+ Cheap flights from Louisville to Sioux Falls (SDF - FSD)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — FSD
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to Sioux Falls with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Sioux Falls
Cheapest
Best
Last-minute
One-way
Cheapest flights from Louisville to Sioux FallsExplore the most affordable flight options available from Louisville to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Louisville to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:14 pm -
1 stop6h 34m
Sun 11/87:00 am -
1 stop4h 43m
Deal found 9/5![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:03 pm -
1 stop7h 26m
Sun 9/276:00 am -
1 stop5h 51m
Deal found 9/5![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
1 stop7h 16m
Sun 9/2012:06 pm -
1 stop4h 23m
Deal found 9/9![American Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop7h 13m
Tue 10/136:20 am -
2 stops8h 29m
Deal found 9/6![American Airlines logo]()
$432
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop7h 13m
Mon 10/127:39 pm -
1 stop15h 31m
Deal found 9/6![American Airlines logo]()
$438
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:19 pm -
1 stop5h 26m
Sun 9/1312:06 pm -
1 stop4h 23m
Deal found 9/7![American Airlines logo]()
$439
Best flights from Louisville to Sioux FallsDiscover carefully curated flight deals from Louisville to Sioux Falls that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Louisville to Sioux Falls that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:14 pm -
1 stop6h 34m
Sun 11/87:00 am -
1 stop4h 43m
Deal found 9/5![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/63:20 pm -
1 stop6h 26m
Tue 2/910:00 am -
1 stop5h 32m
Deal found 9/8![United Airlines logo]()
$444
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:03 am -
2 stops11h 17m
Sun 9/276:00 am -
1 stop5h 51m
Deal found 9/4![American Airlines logo]()
$339
Last-minute flights from Louisville to Sioux FallsDiscover last-minute flight deals from Louisville to Sioux Falls. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Sioux Falls. Data last updated September 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:19 pm -
1 stop5h 26m
Sun 9/1312:06 pm -
1 stop4h 23m
Deal found 9/7![American Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
1 stop7h 16m
Sun 9/2012:06 pm -
1 stop4h 23m
Deal found 9/9![American Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:03 pm -
1 stop7h 26m
Sun 9/276:00 am -
1 stop5h 51m
Deal found 9/5![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop7h 13m
Tue 10/137:05 am -
1 stop4h 05m
Deal found 9/6![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop7h 13m
Mon 10/127:39 pm -
1 stop15h 31m
Deal found 9/6![American Airlines logo]()
$438
One-way flights from Louisville to Sioux FallsSearch for one-way flight options from Louisville to Sioux Falls. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Louisville to Sioux Falls. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:06 pm -
3 stops39h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$252
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:29 am -
1 stop6h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$313
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:46 am -
1 stop6h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:30 am -
1 stop4h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:43 pm -
2 stops8h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$388
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:47 am -
2 stops9h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$415
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:09 pm -
2 stops23h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$425
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:09 pm -
3 stops23h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/273:43 pm -
1 stop5h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$450
Find flight deals from Louisville to Sioux Falls
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Sioux Falls (FSD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (American Airlines) |
One-way from | $252 (Kiwi.com) |
Popular in | April |
Cheapest in | February |
Average price | $318 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Louisville to Sioux Falls that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleSioux Falls
SDF Louisville Intl - FSD Sioux Falls Joe Foss Field
SDFFSD
Louisville Intl
Thu 11/5
1:14 pm-6:48 pm
1 stop6h 34m
Sioux Falls Joe Foss Field
Sun 11/8
7:00 am-12:43 pm
1 stop4h 43m
$319
LouisvilleSioux Falls
SDF Louisville Intl - FSD Sioux Falls Joe Foss Field
SDFFSD
Louisville Intl
Wed 9/23
7:03 am-5:20 pm
2 stops11h 17m
Sioux Falls Joe Foss Field
Sun 9/27
6:00 am-12:51 pm
1 stop5h 51m
$339
LouisvilleSioux Falls
SDF Louisville Intl - FSD Sioux Falls Joe Foss Field
SDFFSD
Louisville Intl
Tue 9/22
11:46 am-5:20 pm
1 stop6h 34m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$369
Quickest round-trip
LouisvilleSioux Falls
SDF Louisville Intl - FSD Sioux Falls Joe Foss Field
SDFFSD
Louisville Intl
Tue 9/22
6:30 am-10:19 am
1 stop4h 49m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$387
LouisvilleSioux Falls
SDF Louisville Intl - FSD Sioux Falls Joe Foss Field
SDFFSD
Louisville Intl
Sat 9/26
3:43 pm-10:51 pm
2 stops8h 08m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$388
LouisvilleSioux Falls
SDF Louisville Intl - FSD Sioux Falls Joe Foss Field
SDFFSD
Louisville Intl
Sat 2/6
3:20 pm-8:46 pm
1 stop6h 26m
Sioux Falls Joe Foss Field
Tue 2/9
10:00 am-4:32 pm
1 stop5h 32m
$444
LouisvilleSioux Falls
SDF Louisville Intl - FSD Sioux Falls Joe Foss Field
SDFFSD
Louisville Intl
Sun 9/27
3:43 pm-7:47 pm
1 stop5h 04m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$450
LouisvilleSioux Falls
SDF Louisville Intl - FSD Sioux Falls Joe Foss Field
SDFFSD
Louisville Intl
Sun 10/11
9:09 pm-7:54 pm
3 stops23h 45m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$571
LouisvilleSioux Falls
SDF Louisville Intl - FSD Sioux Falls Joe Foss Field
SDFFSD
Louisville Intl
Mon 9/28
10:32 am-10:51 pm
2 stops13h 19m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$834
Sorted by cheapest first
Compare providers for flights from Louisville to Sioux Falls
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Sioux Falls in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-Sioux Falls flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Sioux Falls flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Sioux Falls flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-Sioux Falls flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Sioux Falls flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to Sioux Falls
Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Louisville with our price prediction graph.
SDF-FSD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Sioux Falls
Get insights into the airlines that provide service to Sioux Falls. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sioux Falls. Reviews last updated September 9, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Louisville to Sioux Falls by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Louisville to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Sioux Falls?
Book flights to Sioux Falls if you plan to visit one of these locationsYankton
Marshall
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Complete your trip
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Louisville and Sioux Falls flights
Browse other Louisville and Sioux Falls flight options. Last updated on September 9, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Other flights to Sioux Falls
Explore flights to Sioux Falls departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Top 3 airlines flying from Louisville to Sioux Falls
Discover the top 3 airlines that operate flights from Louisville to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$367 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$353 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$312 | Average$351 | FlexibilityNo cancel fee | On-time69% |