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Sioux Falls

$315+ Cheap flights from Knoxville to Sioux Falls (TYS - FSD)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FSD
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
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Cheap flight deals from Knoxville to Sioux Falls

Cheapest flights from Knoxville to Sioux Falls
Explore the most affordable flight options available from Knoxville to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:30 am
TYS
-
FSD
1 stop8h 01m
American Airlines
Sat 12/126:35 am
FSD
-
TYS
1 stop7h 57m
American Airlines
Deal found 7/24$315
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:52 pm
TYS
-
FSD
1 stop6h 38m
American Airlines
Sat 9/126:00 am
FSD
-
TYS
1 stop7h 29m
American Airlines
Deal found 7/24$317
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:16 pm
TYS
-
FSD
1 stop6h 43m
Delta
Sun 8/305:30 am
FSD
-
TYS
1 stop4h 41m
Delta
Deal found 7/27$319
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:20 pm
TYS
-
FSD
2 stops7h 41m
American Airlines
Sun 11/156:00 am
FSD
-
TYS
1 stop7h 05m
American Airlines
Deal found 7/25$322
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:15 am
TYS
-
FSD
2 stops7h 21m
American Airlines
Sun 8/306:24 am
FSD
-
TYS
1 stop5h 27m
American Airlines
Deal found 7/27$324
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:02 pm
TYS
-
FSD
1 stop6h 20m
United Airlines
Mon 9/77:47 am
FSD
-
TYS
1 stop4h 30m
United Airlines
Deal found 7/23$402
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:52 pm
TYS
-
FSD
1 stop6h 38m
American Airlines
Tue 8/115:23 pm
FSD
-
TYS
1 stop5h 23m
American Airlines
Deal found 7/23$414

Find flight deals from Knoxville to Sioux Falls

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Sioux Falls (FSD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$315
(American Airlines)

Popular in

June

Cheapest in

February

Average price

$536
Provider with most accurate pricing for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flights.
Search Deals
From Knoxville McGhee Tyson to Sioux Falls Joe Foss Field
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($134 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Knoxville to Sioux Falls that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Thu 1/21

12:19 pm-4:59 pm

1 stop5h 40m

Sioux Falls Joe Foss Field

Sat 2/27

5:21 pm-11:53 pm

1 stop5h 32m

$317

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 8/28

2:16 pm-7:59 pm

1 stop6h 43m

Sioux Falls Joe Foss Field

Sun 8/30

5:30 am-11:11 am

1 stop4h 41m

$319

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 8/28

11:40 am-4:53 pm

1 stop6h 13m

Sioux Falls Joe Foss Field

Sun 8/30

6:24 am-12:51 pm

1 stop5h 27m

$319
Quickest round-trip

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Thu 9/3

6:02 pm-11:22 pm

1 stop6h 20m

Sioux Falls Joe Foss Field

Mon 9/7

7:47 am-1:17 pm

1 stop4h 30m

$402

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 8/7

6:52 pm-12:30 am

1 stop6h 38m

Sioux Falls Joe Foss Field

Tue 8/11

5:23 pm-11:46 pm

1 stop5h 23m

$414

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 11/20

5:40 pm-9:37 pm

1 stop4h 57m

Sioux Falls Joe Foss Field

Mon 11/23

1:20 pm-10:29 pm

1 stop8h 09m

$519

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/24

Sorted by cheapest first

Compare providers for flights from Knoxville to Sioux Falls

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Sioux Falls in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Sioux Falls flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Sioux Falls flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Sioux Falls flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Sioux Falls flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Sioux Falls flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Sioux Falls

What is the cheapest month to book a flight from Knoxville to Sioux Falls?

Currently, February is the cheapest month in which you can book a flight from Knoxville to Sioux Falls (average of $269). Flying from Knoxville to Sioux Falls in June is currently the most expensive (average of $850). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Knoxville to Sioux Falls?

Airfare is below average for this route at the moment.

Knoxville to Sioux Falls flights typically cost between $385 and $508 in November.
The cheapest round-trip price found within the last 5 days was $315 on American Airlines (Nov 25-Dec 12).

Reviews of airlines servicing Sioux Falls

Get insights into the airlines that provide service to Sioux Falls. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sioux Falls. Reviews last updated July 27, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Knoxville to Sioux Falls by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,482 reviews

Entertainment

7.8

Comfort

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,482 reviews
Delta
7.8
Good
8,482 reviews

Entertainment

7.8

Comfort

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
10,041 reviews
Delta
7.8
Good
8,482 reviews

Entertainment

7.8

Comfort

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,836 reviews
Delta
7.8
Good
8,482 reviews

Entertainment

7.8

Comfort

7.8

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Sioux Falls?

    Departing from Knoxville to Sioux Falls will take you 5h 40m. The distance from Knoxville to Sioux Falls is about 863 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Sioux Falls round-trip?

    Flying on American Airlines is currently your cheapest option to Sioux Falls, with prices starting at $248. Additional round-trip tickets that might be worth considering are offered by United Airlines and Delta, with the lowest prices starting at $269 and $339, respectively. Users have found that American Airlines is 46% cheaper than the other options available to this destination.

  • Can I find deals for flights from Knoxville to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Knoxville to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Sioux Falls.

  • Can I find deals for business class flights from Knoxville to Sioux Falls?

    Yes. Cheapflights offers flight deals from Knoxville to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Sioux Falls?

    Currently, February is the cheapest month in which you can book a flight from Knoxville to Sioux Falls (average of $269). Flying from Knoxville to Sioux Falls in June is currently the most expensive (average of $850). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Marshall
Yankton

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Knoxville to Sioux Falls

Discover the top 3 airlines that operate flights from Knoxville to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$470FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$269Average$408FlexibilityNo cancel feeOn-time69%
DeltaCheapest$339Average$448FlexibilityNo cancel feeOn-timeN/A

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