
Keep the following information in mind while searching for Knoxville to South Dakota flight deals. Data was last updated November 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $301 (American Airlines) |
One-way from | $284 (American Airlines) |
Popular in | June |
Cheapest in | February |
Average price | $385 |
Fly from
Fly to
Route
Depart
Return
KnoxvilleSioux Falls
TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field
TYSFSD
Knoxville McGhee Tyson
Mon 11/30
8:50 pm-12:44 am
1 stop4h 54m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
KnoxvilleRapid City
TYS Knoxville McGhee Tyson - RAP Rapid City
TYSRAP
Knoxville McGhee Tyson
Sat 12/5
7:10 am-3:53 pm
2 stops10h 43m
Rapid City
Sat 12/12
4:36 pm-11:24 pm
1 stop4h 48m
KnoxvilleRapid City
TYS Knoxville McGhee Tyson - RAP Rapid City
TYSRAP
Knoxville McGhee Tyson
Sat 12/5
6:00 am-1:03 pm
2 stops9h 03m
Rapid City
Sat 12/12
7:00 am-5:00 pm
2 stops8h 00m
KnoxvilleSioux Falls
TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field
TYSFSD
Knoxville McGhee Tyson
Mon 11/30
6:41 pm-2:47 pm
3 stops45h 06m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
KnoxvilleSioux Falls
TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field
TYSFSD
Knoxville McGhee Tyson
Tue 11/17
4:00 pm-7:56 pm
1 stop4h 56m
Sioux Falls Joe Foss Field
Sat 11/21
5:00 pm-11:11 pm
1 stop5h 11m
KnoxvilleSioux Falls
TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field
TYSFSD
Knoxville McGhee Tyson
Thu 11/19
5:40 pm-9:37 pm
1 stop4h 57m
Sioux Falls Joe Foss Field
Mon 11/23
1:20 pm-10:32 pm
1 stop8h 12m
KnoxvilleRapid City
TYS Knoxville McGhee Tyson - RAP Rapid City
TYSRAP
Knoxville McGhee Tyson
Tue 5/4
5:15 pm-10:39 pm
2 stops7h 24m
Rapid City
Tue 5/11
2:25 pm-11:46 pm
2 stops7h 21m
KnoxvilleSioux Falls
TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field
TYSFSD
Knoxville McGhee Tyson
Thu 11/19
8:50 pm-12:48 am
1 stop4h 58m
Sioux Falls Joe Foss Field
Mon 11/23
6:00 am-4:36 pm
2 stops9h 36m
KnoxvilleRapid City
TYS Knoxville McGhee Tyson - RAP Rapid City
TYSRAP
Knoxville McGhee Tyson
Wed 1/20
4:28 pm-8:30 pm
1 stop6h 02m
Rapid City
Sat 1/23
7:00 am-2:56 pm
1 stop5h 56m
KnoxvilleRapid City
TYS Knoxville McGhee Tyson - RAP Rapid City
TYSRAP
Knoxville McGhee Tyson
Thu 11/19
7:00 am-3:19 pm
2 stops10h 19m
Rapid City
Mon 11/23
1:30 pm-8:54 pm
1 stop5h 24m
Everything you need to know about your flight from Knoxville to South Dakota
Food
Comfort
Entertainment
Boarding
Overall
Crew
Reviews
Ellen,Oct 2026
GRR - ATL
Food
Comfort
Entertainment
Boarding
Overall
Crew
Reviews
Ellen,Oct 2026
GRR - ATL
Food
Comfort
Entertainment
Boarding
Overall
Crew
Reviews
Ellen,Oct 2026
GRR - ATL
Food
Comfort
Entertainment
Boarding
Overall
Crew
Reviews
Ellen,Oct 2026
GRR - ATL
Find useful and relevant information for your journey from Knoxville to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$288 | Average$480 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$535 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$339 | Average$448 | FlexibilityNo cancel fee | On-timeN/A |