$215+ Cheap flights from Knoxville (TYS) to South Dakota
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FSD
Oct 25 — Nov 11
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to South Dakota with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Knoxville to South DakotaExplore the most affordable flight options available from Knoxville to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
Explore the most affordable flight options available from Knoxville to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:26 pm -
1 stop6h 30m
Tue 11/36:11 am -
1 stop5h 54m
Deal found 9/24![American Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:25 am -
1 stop5h 48m
Tue 11/36:00 am -
1 stop7h 05m
Deal found 9/21![American Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:45 am -
1 stop5h 46m
Tue 11/35:00 am -
2 stops9h 59m
Deal found 9/24![United Airlines logo]()
$336
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:21 pm -
1 stop8h 02m
Wed 9/306:30 am -
1 stop5h 23m
Deal found 9/20![American Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:26 am -
2 stops10h 32m
Tue 11/311:29 am -
2 stops8h 33m
Deal found 9/24![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:40 am -
2 stops7h 05m
Mon 10/262:37 pm -
2 stops7h 22m
Deal found 9/20![Delta logo]()
$380
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:32 pm -
1 stop5h 55m
Sun 11/81:09 pm -
1 stop8h 23m
Deal found 9/22![American Airlines logo]()
$381
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:05 pm -
1 stop5h 38m
Sat 11/75:00 am -
2 stops9h 59m
Deal found 9/22![United Airlines logo]()
$396
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:05 pm -
1 stop7h 39m
Mon 11/21:20 pm -
1 stop8h 12m
Deal found 9/23![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:08 pm -
1 stop6h 39m
Sun 9/275:30 am -
1 stop5h 36m
Deal found 9/20![Delta logo]()
$444
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:15 pm -
1 stop5h 14m
Sun 9/276:00 am -
2 stops9h 16m
Deal found 9/24![American Airlines logo]()
$464
Best flights from Knoxville to South DakotaDiscover carefully curated flight deals from Knoxville to South Dakota that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
Discover carefully curated flight deals from Knoxville to South Dakota that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:25 am -
1 stop5h 48m
Tue 11/36:00 am -
1 stop7h 05m
Deal found 9/21![American Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:26 am -
2 stops10h 32m
Tue 11/311:29 am -
2 stops8h 33m
Deal found 9/24![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:05 pm -
1 stop5h 38m
Sat 11/75:00 am -
2 stops9h 59m
Deal found 9/22![United Airlines logo]()
$396
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/77:50 am -
1 stop5h 17m
Mon 1/117:00 am -
1 stop5h 59m
Deal found 9/20![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:16 pm -
1 stop5h 14m
Mon 10/262:37 pm -
2 stops7h 22m
Deal found 9/20![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop6h 15m
Tue 10/201:37 pm -
1 stop5h 12m
Deal found 9/20![United Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:26 pm -
1 stop6h 30m
Mon 10/2612:51 pm -
1 stop8h 37m
Deal found 9/20![American Airlines logo]()
$416
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:40 am -
2 stops7h 05m
Sun 11/82:37 pm -
1 stop6h 25m
Deal found 9/24![Delta logo]()
$428
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:05 pm -
1 stop5h 38m
Sun 11/87:00 am -
2 stops7h 59m
Deal found 9/22![United Airlines logo]()
$430
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:05 pm -
1 stop7h 39m
Mon 11/21:20 pm -
1 stop8h 12m
Deal found 9/23![United Airlines logo]()
$439
Last-minute flights from Knoxville to South DakotaDiscover last-minute flight deals from Knoxville to South Dakota. Data last updated September 25, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to South Dakota. Data last updated September 25, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:08 pm -
1 stop6h 39m
Sun 9/275:30 am -
1 stop5h 36m
Deal found 9/20![Delta logo]()
$444
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:15 pm -
1 stop5h 14m
Sun 9/276:00 am -
2 stops9h 16m
Deal found 9/24![American Airlines logo]()
$464
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:21 pm -
1 stop8h 02m
Wed 9/306:30 am -
1 stop5h 23m
Deal found 9/20![American Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:25 am -
1 stop5h 48m
Tue 11/36:00 am -
1 stop7h 05m
Deal found 9/21![American Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:40 am -
2 stops7h 05m
Mon 10/262:37 pm -
2 stops7h 22m
Deal found 9/20![Delta logo]()
$380
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:26 pm -
1 stop6h 30m
Mon 10/2612:51 pm -
1 stop8h 37m
Deal found 9/20![American Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:26 pm -
1 stop6h 30m
Tue 11/36:11 am -
1 stop5h 54m
Deal found 9/24![American Airlines logo]()
$315
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:45 am -
1 stop5h 46m
Tue 11/35:00 am -
2 stops9h 59m
Deal found 9/24![United Airlines logo]()
$336
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:26 am -
2 stops10h 32m
Tue 11/311:29 am -
2 stops8h 33m
Deal found 9/24![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:05 pm -
1 stop7h 39m
Mon 11/21:20 pm -
1 stop8h 12m
Deal found 9/23![United Airlines logo]()
$439
One-way flights from Knoxville to South DakotaSearch for one-way flight options from Knoxville to South Dakota. Find affordable one-way fares based on user searches. Data last updated September 25, 2026.
Search for one-way flight options from Knoxville to South Dakota. Find affordable one-way fares based on user searches. Data last updated September 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:00 am -
1 stop12h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Allegiant Air logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:09 pm -
2 stops38h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$272
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:52 pm -
1 stop4h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![American Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:30 pm -
1 stop6h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![American Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/302:50 pm -
2 stops46h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:26 pm -
1 stop6h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$376
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am -
2 stops13h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![United Airlines logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:30 am -
2 stops40h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:28 am -
3 stops29h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$419
Find flight deals from Knoxville to South Dakota
Keep the following information in mind while searching for Knoxville to South Dakota flight deals. Data was last updated September 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $315 (American Airlines) |
One-way from | $215 (Kiwi.com) |
Popular in | June |
Cheapest in | February |
Average price | $570 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to South Dakota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
Use the filters below to find and compare flights from Knoxville to South Dakota that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleSioux Falls
TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field
TYSFSD
Knoxville McGhee Tyson
Sun 11/8
7:00 am-6:24 pm
1 stop12h 24m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$215
Quickest round-trip
KnoxvilleSioux Falls
TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field
TYSFSD
Knoxville McGhee Tyson
Mon 11/9
8:52 pm-12:29 am
1 stop4h 37m
Sioux Falls Joe Foss Field
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
KnoxvilleSioux Falls
TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field
TYSFSD
Knoxville McGhee Tyson
Tue 10/20
7:25 am-12:13 pm
1 stop5h 48m
Sioux Falls Joe Foss Field
Tue 11/3
6:00 am-2:05 pm
1 stop7h 05m
$330
KnoxvilleSioux Falls
TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field
TYSFSD
Knoxville McGhee Tyson
Thu 1/7
7:50 am-12:07 pm
1 stop5h 17m
Sioux Falls Joe Foss Field
Mon 1/11
7:00 am-1:59 pm
1 stop5h 59m
$339
KnoxvilleRapid City
TYS Knoxville McGhee Tyson - RAP Rapid City
TYSRAP
Knoxville McGhee Tyson
Mon 11/30
5:30 pm-9:34 pm
1 stop6h 04m
Rapid City
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$359
KnoxvilleRapid City
TYS Knoxville McGhee Tyson - RAP Rapid City
TYSRAP
Knoxville McGhee Tyson
Mon 11/30
2:50 pm-11:17 am
2 stops46h 27m
Rapid City
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$372
KnoxvilleRapid City
TYS Knoxville McGhee Tyson - RAP Rapid City
TYSRAP
Knoxville McGhee Tyson
Fri 10/30
7:26 am-3:58 pm
2 stops10h 32m
Rapid City
Tue 11/3
11:29 am-10:02 pm
2 stops8h 33m
$374
KnoxvilleRapid City
TYS Knoxville McGhee Tyson - RAP Rapid City
TYSRAP
Knoxville McGhee Tyson
Wed 10/21
7:16 pm-10:30 pm
1 stop5h 14m
Rapid City
Mon 10/26
2:37 pm-11:59 pm
2 stops7h 22m
$375
KnoxvilleRapid City
TYS Knoxville McGhee Tyson - RAP Rapid City
TYSRAP
Knoxville McGhee Tyson
Wed 10/7
5:26 pm-9:56 pm
1 stop6h 30m
Rapid City
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$376
KnoxvilleRapid City
TYS Knoxville McGhee Tyson - RAP Rapid City
TYSRAP
Knoxville McGhee Tyson
Wed 10/7
9:45 am-8:52 pm
2 stops13h 07m
Rapid City
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$391
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Knoxville to South Dakota
Have a flexible travel schedule? Discover the best time to fly to South Dakota from Knoxville with our price prediction graph.
TYS-RAP
TYS-FSD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to South Dakota
TYS-USSD
TYS-RAP
TYS-FSD
What is the cheapest month to book a flight from Knoxville to South Dakota?
Currently, January is the cheapest month in which you can book a flight from Knoxville to South Dakota (average of $340). Flying from Knoxville to South Dakota in June is currently the most expensive (average of $632). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to South Dakota?
Airfare is below average for this route at the moment.
Knoxville to South Dakota flights typically cost between $486 and $615 in October.The cheapest round-trip price found within the last 5 days was $330 on American Airlines (Oct 20-Nov 3).
Reviews of airlines servicing South Dakota
Get insights into the airlines that provide service to South Dakota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Dakota. Reviews last updated September 25, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Knoxville to South Dakota have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to South Dakota by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Knoxville to South Dakota, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and South Dakota flights
Browse other Knoxville and South Dakota flight options. Last updated on September 25, 2026.
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Knoxville to South Dakota flights
Consider these flights traveling from Knoxville to South Dakota.
Top 3 airlines flying from Knoxville to South Dakota
Discover the top 3 airlines that operate flights from Knoxville to South Dakota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$288 | Average$480 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$493 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$339 | Average$448 | FlexibilityNo cancel fee | On-timeN/A |