$147+ Cheap flights from Sioux Falls to Indianapolis (FSD - IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — IND
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Sioux Falls to IndianapolisExplore the most affordable flight options available from Sioux Falls to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Sioux Falls to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:18 pm -
1 stop4h 20m
Sat 11/149:03 pm -
1 stop4h 26m
Deal found 9/16![American Airlines logo]()
$331
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:30 am -
1 stop5h 58m
Fri 11/136:35 am -
1 stop4h 45m
Deal found 9/15![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:18 pm -
1 stop4h 20m
Mon 11/99:03 pm -
1 stop4h 26m
Deal found 9/16![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:08 pm -
2 stops10h 38m
Fri 11/131:10 pm -
1 stop6h 38m
Deal found 9/15![American Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:08 pm -
2 stops10h 30m
Sat 12/1212:39 pm -
2 stops9h 15m
Deal found 9/16![American Airlines logo]()
$342
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:50 am -
1 stop6h 24m
Sun 10/46:36 pm -
1 stop5h 35m
Deal found 9/12![United Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:50 am -
1 stop3h 52m
Mon 10/54:55 pm -
1 stop7h 16m
Deal found 9/15![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:53 pm -
1 stop7h 24m
Sun 10/258:58 pm -
1 stop4h 43m
Deal found 9/16![American Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:56 pm -
2 stops9h 13m
Mon 10/52:13 pm -
1 stop8h 00m
Deal found 9/15![American Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:00 pm -
1 stop4h 57m
Tue 11/106:35 am -
1 stop4h 45m
Deal found 9/16![Delta logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:39 pm -
2 stops36h 51m
Fri 11/68:00 am -
1 stop11h 23m
Deal found 9/16![Multiple Airlines logo]()
$378
Best flights from Sioux Falls to IndianapolisDiscover carefully curated flight deals from Sioux Falls to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Sioux Falls to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:18 pm -
1 stop4h 20m
Sat 11/1411:01 am -
1 stop7h 26m
Deal found 9/13![American Airlines logo]()
$331
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:50 am -
1 stop6h 24m
Sun 10/46:36 pm -
1 stop5h 35m
Deal found 9/12![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:00 pm -
1 stop4h 57m
Tue 11/106:35 am -
1 stop4h 45m
Deal found 9/16![Delta logo]()
$375
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:08 pm -
2 stops10h 38m
Fri 11/131:10 pm -
1 stop6h 38m
Deal found 9/12![American Airlines logo]()
$340
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:50 am -
1 stop3h 52m
Wed 10/283:44 pm -
1 stop5h 20m
Deal found 9/15![United Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:53 pm -
1 stop7h 24m
Mon 10/198:58 pm -
1 stop4h 43m
Deal found 9/12![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:00 am -
1 stop4h 19m
Mon 9/218:52 pm -
1 stop4h 37m
Deal found 9/14![American Airlines logo]()
$417
Last-minute flights from Sioux Falls to IndianapolisDiscover last-minute flight deals from Sioux Falls to Indianapolis. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Indianapolis. Data last updated September 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:00 am -
1 stop4h 19m
Mon 9/218:52 pm -
1 stop4h 37m
Deal found 9/14![American Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:50 am -
1 stop3h 52m
Mon 10/54:55 pm -
1 stop7h 16m
Deal found 9/15![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:56 pm -
2 stops9h 13m
Mon 10/52:13 pm -
1 stop8h 00m
Deal found 9/15![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:50 am -
1 stop6h 24m
Sun 10/46:36 pm -
1 stop5h 35m
Deal found 9/12![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:48 pm -
1 stop3h 40m
Tue 10/208:58 pm -
1 stop4h 43m
Deal found 9/15![American Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:53 pm -
1 stop7h 24m
Mon 10/198:58 pm -
1 stop4h 43m
Deal found 9/12![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:53 pm -
1 stop7h 24m
Sun 10/258:58 pm -
1 stop4h 43m
Deal found 9/16![American Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:50 am -
1 stop3h 52m
Wed 10/283:44 pm -
1 stop5h 20m
Deal found 9/15![United Airlines logo]()
$411
One-way flights from Sioux Falls to IndianapolisSearch for one-way flight options from Sioux Falls to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Sioux Falls to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:32 pm -
3 stops43h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:19 pm -
1 stop25h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Allegiant Air logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:28 am -
2 stops28h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:19 pm -
3 stops42h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:56 pm -
1 stop15h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Allegiant Air logo]()
$281
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:00 pm -
1 stop4h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$284
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:08 pm -
2 stops10h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$289
Find flight deals from Sioux Falls to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $331 (American Airlines) |
One-way from | $147 (Kiwi.com) |
Popular in | August |
Cheapest in | October |
Average price | $458 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Sioux Falls to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsIndianapolis
FSD Sioux Falls Joe Foss Field - IND Indianapolis
FSDIND
Sioux Falls Joe Foss Field
Mon 11/16
10:32 pm-6:57 pm
3 stops43h 25m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$147
Sioux FallsIndianapolis
FSD Sioux Falls Joe Foss Field - IND Indianapolis
FSDIND
Sioux Falls Joe Foss Field
Thu 11/12
5:19 pm-7:43 pm
1 stop25h 24m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$211
Quickest round-trip
Sioux FallsIndianapolis
FSD Sioux Falls Joe Foss Field - IND Indianapolis
FSDIND
Sioux Falls Joe Foss Field
Thu 10/15
7:50 am-12:42 pm
1 stop3h 52m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
Sioux FallsIndianapolis
FSD Sioux Falls Joe Foss Field - IND Indianapolis
FSDIND
Sioux Falls Joe Foss Field
Fri 11/13
7:00 am-2:54 pm
1 stop6h 54m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
Sioux FallsIndianapolis
FSD Sioux Falls Joe Foss Field - IND Indianapolis
FSDIND
Sioux Falls Joe Foss Field
Mon 11/16
8:31 am-3:24 pm
1 stop5h 53m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
Sioux FallsIndianapolis
FSD Sioux Falls Joe Foss Field - IND Indianapolis
FSDIND
Sioux Falls Joe Foss Field
Sat 11/14
11:14 am-4:18 pm
1 stop4h 04m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
Sioux FallsIndianapolis
FSD Sioux Falls Joe Foss Field - IND Indianapolis
FSDIND
Sioux Falls Joe Foss Field
Fri 11/13
5:00 pm-10:59 pm
1 stop4h 59m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
Sioux FallsIndianapolis
FSD Sioux Falls Joe Foss Field - IND Indianapolis
FSDIND
Sioux Falls Joe Foss Field
Wed 11/11
7:18 pm-12:38 am
1 stop4h 20m
Indianapolis
Sat 11/14
11:01 am-5:27 pm
1 stop7h 26m
$331
Sioux FallsIndianapolis
FSD Sioux Falls Joe Foss Field - IND Indianapolis
FSDIND
Sioux Falls Joe Foss Field
Sat 11/7
1:08 pm-12:46 am
2 stops10h 38m
Indianapolis
Fri 11/13
1:10 pm-6:48 pm
1 stop6h 38m
$340
Sioux FallsIndianapolis
FSD Sioux Falls Joe Foss Field - IND Indianapolis
FSDIND
Sioux Falls Joe Foss Field
Fri 10/2
7:50 am-3:14 pm
1 stop6h 24m
Indianapolis
Sun 10/4
6:36 pm-11:11 pm
1 stop5h 35m
$354
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Indianapolis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Sioux Falls with our price prediction graph.
FSD-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Indianapolis
What is the cheapest month to book a flight from Sioux Falls to Indianapolis?
Currently, October is the cheapest month in which you can book a flight from Sioux Falls to Indianapolis (average of $323). Flying from Sioux Falls to Indianapolis in August is currently the most expensive (average of $511). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Sioux Falls to Indianapolis?
Airfare is below average for this route at the moment.
Sioux Falls to Indianapolis flights typically cost between $402 and $486 in November.The cheapest round-trip price found within the last 5 days was $331 on American Airlines (Nov 11-Nov 14).
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated September 17, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Entertainment
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Entertainment
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Entertainment
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Entertainment
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Greenwood
Plainfield
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Carmel
Noblesville
Bloomington
Speedway
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Browse other Sioux Falls and Indianapolis flight options. Last updated on September 17, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Sioux Falls to Indianapolis
Discover the top 3 airlines that operate flights from Sioux Falls to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$253 | Average$378 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$273 | Average$458 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$275 | Average$398 | FlexibilityNo cancel fee | On-time69% |