$122+ Cheap flights from Minnesota to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — CHS
Oct 29 — Nov 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Minnesota to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Minnesota to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Minnesota to South CarolinaExplore the most affordable flight options available from Minnesota to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
Explore the most affordable flight options available from Minnesota to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:42 am -
Nonstop2h 46m
Tue 11/173:23 pm -
Nonstop3h 00m
Deal found 9/28![Delta logo]()
$259
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:41 pm -
1 stop6h 19m
Tue 10/206:43 pm -
1 stop6h 30m
Deal found 9/27![American Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:45 am -
2 stops8h 15m
Wed 10/286:20 am -
1 stop5h 09m
Deal found 9/24![United Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:30 am -
2 stops6h 10m
Tue 11/37:05 am -
2 stops11h 25m
Deal found 9/24![Southwest logo]()
$269
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop7h 00m
Wed 12/910:22 am -
1 stop6h 27m
Deal found 9/26![United Airlines logo]()
$274
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:10 am -
2 stops10h 25m
Thu 11/126:40 am -
2 stops9h 00m
Deal found 9/24![Southwest logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:36 pm -
2 stops21h 01m
Wed 11/186:00 am -
1 stop9h 24m
Deal found 9/26![Multiple Airlines logo]()
$276
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/212:10 pm -
1 stop6h 49m
Tue 12/16:27 pm -
1 stop6h 38m
Deal found 9/25![American Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:01 pm -
2 stops16h 37m
Tue 11/33:00 pm -
1 stop24h 19m
Deal found 9/24![Multiple Airlines logo]()
$278
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop6h 56m
Tue 11/178:30 am -
1 stop6h 57m
Deal found 9/27![United Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:12 pm -
1 stop7h 09m
Sat 12/126:45 am -
2 stops8h 31m
Deal found 9/28![United Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/33:01 pm -
2 stops16h 37m
Sat 11/77:00 am -
1 stop10h 56m
Deal found 9/25![Multiple Airlines logo]()
$283
Best flights from Minnesota to South CarolinaDiscover carefully curated flight deals from Minnesota to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
Discover carefully curated flight deals from Minnesota to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:40 pm -
1 stop4h 35m
Tue 11/102:50 pm -
2 stops9h 10m
Deal found 9/24![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:35 am -
1 stop4h 21m
Thu 10/295:50 am -
2 stops9h 35m
Deal found 9/25![United Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:00 am -
1 stop6h 00m
Mon 11/93:23 pm -
Nonstop3h 00m
Deal found 9/23![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:19 pm -
2 stops15h 46m
Thu 10/296:08 pm -
1 stop5h 07m
Deal found 9/27![American Airlines logo]()
$419
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:20 pm -
1 stop5h 05m
Tue 12/88:10 am -
1 stop7h 40m
Deal found 9/28![Southwest logo]()
$329
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
2 stops7h 17m
Tue 12/12:29 pm -
1 stop6h 15m
Deal found 9/25![United Airlines logo]()
$352
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
2 stops6h 10m
Thu 10/292:10 pm -
2 stops9h 45m
Deal found 9/25![Southwest logo]()
$331
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
1 stop6h 12m
Tue 10/272:52 pm -
2 stops9h 07m
Deal found 9/27![United Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:00 am -
1 stop5h 15m
Fri 12/111:40 pm -
2 stops10h 55m
Deal found 9/26![Southwest logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:12 pm -
2 stops9h 47m
Mon 11/167:00 pm -
1 stop4h 59m
Deal found 9/23![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:20 pm -
1 stop6h 35m
Sat 11/76:01 am -
1 stop7h 02m
Deal found 9/26![American Airlines logo]()
$465
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:54 am -
2 stops8h 38m
Sat 12/56:45 am -
2 stops12h 25m
Deal found 9/26![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:50 am -
2 stops9h 55m
Wed 10/286:40 am -
2 stops8h 50m
Deal found 9/27![Southwest logo]()
$379
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:42 am -
Nonstop2h 46m
Mon 11/233:20 pm -
Nonstop3h 04m
Deal found 9/28![Delta logo]()
$508
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:19 pm -
2 stops15h 46m
Sat 10/311:55 pm -
1 stop11h 18m
Deal found 9/24![American Airlines logo]()
$470
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:05 am -
1 stop5h 09m
Fri 10/305:59 pm -
1 stop17h 20m
Deal found 9/28![Delta logo]()
$508
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/124:15 pm -
1 stop5h 35m
Sat 10/316:40 am -
2 stops10h 20m
Deal found 9/25![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:19 pm -
1 stop4h 50m
Sun 10/116:15 am -
1 stop5h 05m
Deal found 9/24![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:27 pm -
1 stop6h 32m
Mon 11/305:12 pm -
1 stop7h 54m
Deal found 9/26![American Airlines logo]()
$505
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:39 am -
Nonstop2h 49m
Wed 10/213:23 pm -
Nonstop2h 59m
Deal found 9/24![Delta logo]()
$523
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am -
2 stops7h 16m
Sun 11/16:20 am -
1 stop5h 03m
Deal found 9/27![United Airlines logo]()
$401
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:15 am -
2 stops7h 55m
Tue 11/31:25 pm -
2 stops9h 55m
Deal found 9/28![Southwest logo]()
$404
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:05 am -
1 stop7h 24m
Wed 12/307:10 pm -
2 stops14h 18m
Deal found 9/25![American Airlines logo]()
$510
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
2 stops7h 17m
Sat 10/3112:21 pm -
2 stops11h 38m
Deal found 9/24![United Airlines logo]()
$406
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:10 am -
2 stops6h 50m
Fri 12/43:25 pm -
2 stops7h 55m
Deal found 9/24![Southwest logo]()
$408
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/267:15 am -
1 stop4h 59m
Mon 12/283:39 pm -
1 stop18h 40m
Deal found 9/24![Delta logo]()
$592
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:05 am -
1 stop7h 12m
Tue 12/83:44 pm -
1 stop7h 06m
Deal found 9/28![American Airlines logo]()
$548
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:05 pm -
1 stop8h 54m
Fri 10/304:29 pm -
1 stop8h 15m
Deal found 9/27![United Airlines logo]()
$412
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:30 am -
2 stops9h 45m
Wed 11/183:25 pm -
2 stops8h 35m
Deal found 9/28![Southwest logo]()
$449
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:25 am -
1 stop4h 18m
Wed 10/285:40 am -
1 stop5h 39m
Deal found 9/28![Delta logo]()
$637
Last-minute flights from Minnesota to South CarolinaDiscover last-minute flight deals from Minnesota to South Carolina. Data last updated September 29, 2026 and is based on user searches.
Discover last-minute flight deals from Minnesota to South Carolina. Data last updated September 29, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:14 pm -
1 stop7h 03m
Tue 11/36:20 am -
1 stop6h 50m
Deal found 9/25![United Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:05 am -
1 stop10h 39m
Mon 11/28:32 pm -
2 stops42h 34m
Deal found 9/24![Multiple Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:41 pm -
1 stop6h 19m
Tue 10/206:43 pm -
1 stop6h 30m
Deal found 9/27![American Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:19 pm -
1 stop4h 58m
Tue 11/35:40 am -
2 stops9h 47m
Deal found 9/24![United Airlines logo]()
$318
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:45 am -
2 stops8h 15m
Wed 10/286:20 am -
1 stop5h 09m
Deal found 9/24![United Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:30 am -
2 stops6h 10m
Tue 11/37:05 am -
2 stops11h 25m
Deal found 9/24![Southwest logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:42 pm -
1 stop13h 56m
Wed 10/286:00 am -
2 stops29h 42m
Deal found 9/27![Multiple Airlines logo]()
$297
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:45 pm -
1 stop7h 06m
Mon 10/2611:05 am -
1 stop7h 11m
Deal found 9/27![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:00 am -
1 stop7h 35m
Mon 10/266:43 pm -
1 stop6h 30m
Deal found 9/27![American Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:41 pm -
1 stop6h 19m
Tue 10/276:32 am -
2 stops7h 58m
Deal found 9/25![American Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:01 pm -
2 stops16h 37m
Tue 11/33:00 pm -
1 stop24h 19m
Deal found 9/24![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:25 am -
1 stop9h 12m
Tue 11/33:00 pm -
2 stops24h 06m
Deal found 9/28![Multiple Airlines logo]()
$314
One-way flights from Minnesota to South CarolinaSearch for one-way flight options from Minnesota to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
Search for one-way flight options from Minnesota to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:36 pm -
2 stops21h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:01 pm -
2 stops16h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:01 pm -
2 stops27h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:33 am -
2 stops22h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:36 pm -
2 stops21h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$130
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:16 pm -
1 stop6h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![United Airlines logo]()
$130
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:50 am -
2 stops8h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Southwest logo]()
$135
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:40 pm -
1 stop5h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Southwest logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:01 pm -
2 stops20h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:33 am -
2 stops49h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:33 am -
2 stops28h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:01 pm -
2 stops20h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$154
Find flight deals from Minnesota to South Carolina
Keep the following information in mind while searching for Minnesota to South Carolina flight deals. Data was last updated September 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $259 (Delta) |
One-way from | $122 (Kiwi.com) |
Popular in | March |
Cheapest in | April |
Average price | $399 |
Good round-trip deal | $339 or less |
Good one-way deal | $213 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Minnesota to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
Use the filters below to find and compare flights from Minnesota to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Wed 10/21
6:15 am-3:01 pm
1 stop7h 46m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$130
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Tue 10/20
9:45 am-5:05 pm
1 stop6h 20m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$130
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Tue 10/20
5:30 am-12:40 pm
2 stops6h 10m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$135
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Tue 10/27
11:00 am-9:05 pm
2 stops9h 05m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$135
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Sat 10/17
12:03 pm-11:13 pm
2 stops10h 10m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$155
MinneapolisMyrtle Beach
MSP Minneapolis St Paul - MYR Myrtle Beach Intl
MSPMYR
Minneapolis St Paul
Wed 11/18
1:20 pm-7:25 pm
1 stop5h 05m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$165
MinneapolisCharleston
MSP Minneapolis St Paul - CHS Charleston
MSPCHS
Minneapolis St Paul
Thu 12/24
1:20 pm-7:30 pm
1 stop5h 10m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$185
MinneapolisCharleston
MSP Minneapolis St Paul - CHS Charleston
MSPCHS
Minneapolis St Paul
Fri 10/30
4:15 pm-9:35 pm
1 stop4h 20m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$185
MinneapolisMyrtle Beach
MSP Minneapolis St Paul - MYR Myrtle Beach Intl
MSPMYR
Minneapolis St Paul
Sat 10/24
9:33 am-8:47 am
2 stops22h 14m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$186
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Fri 12/11
11:00 am-8:10 pm
2 stops8h 10m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$188
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Minnesota to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Minnesota with our price prediction graph.
MSP-GSP
MSP-MYR
MSP-CHS
MSP-CAE
MSP-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minnesota to South Carolina
USMN-USSC
MSP-GSP
MSP-MYR
MSP-CHS
MSP-CAE
What is the cheapest month to book a flight from Minnesota to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Minnesota to South Carolina (average of $325). Flying from Minnesota to South Carolina in March is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MN to SC?
Find hourly flight availability from Minnesota to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 29, 2026.
When flying from Minnesota to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from Minnesota to South Carolina
Explore weekly flight availability from Minnesota to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 29, 2026.
The most flights from USMN to USSC are scheduled on a Monday (3 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Minnesota to South Carolina?
Airfare is below average for this route at the moment.
Minnesota to South Carolina flights typically cost between $348 and $494 in November.The cheapest round-trip price found within the last 5 days was $259 on Delta (Nov 10-Nov 17).
How far ahead should I book a flight from Minnesota to South Carolina?
Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from Minnesota to South Carolina. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 29, 2026.
Read through reviews of airlines operating flights from Minnesota to South Carolina, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Related info for your journey
Find useful and relevant information for your journey from Minnesota to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Minnesota to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Minnesota to South Carolina by cabin class
Find flights from Minnesota to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minnesota and South Carolina flights
Browse other Minnesota and South Carolina flight options. Last updated on September 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Minnesota after your stay in South Carolina
Minnesota to South Carolina flights
Consider these flights traveling from Minnesota to South Carolina.
Top 5 airlines flying from Minnesota to South Carolina
Discover the top 5 airlines that operate flights from Minnesota to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$68 | Average$260 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$205 | Average$450 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$218 | Average$473 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$237 | Average$400 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$261 | Average$444 | FlexibilityNo cancel fee | On-time71% |