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South Carolina

$37+ Cheap flights from Maine to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Maine to South Carolina

Cheapest flights from Maine to South Carolina
Explore the most affordable flight options available from Maine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1812:29 pmBOS - MYR
1 stop6h 08mSpirit Airlines
Fri 1/233:39 pmMYR - BOS
Nonstop2h 05mSpirit Airlines
Deal found 12/16$231
This Priceline deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:00 amBOS - CHS
Nonstop2h 36mJetBlue
Thu 1/112:21 pmCHS - BOS
Nonstop2h 15mJetBlue
Deal found 12/17$247
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amBOS - CLT
1 stop4h 53mAmerican Airlines
Thu 1/16:59 pmCLT - BOS
Nonstop2h 12mAmerican Airlines
Deal found 12/16$249
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:56 amBOS - CLT
1 stop7h 33mAmerican Airlines
Sun 12/286:59 pmCLT - BOS
Nonstop2h 12mAmerican Airlines
Deal found 12/16$252
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amBOS - CHS
1 stop7h 03mAmerican Airlines
Mon 1/55:10 amCHS - BOS
1 stop4h 44mAmerican Airlines
Deal found 12/17$252
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:35 amBOS - CHS
Nonstop2h 47mDelta
Mon 1/53:02 pmCHS - BOS
1 stop5h 22mDelta
Deal found 12/17$257
This Travelocity deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:08 pmBOS - CLT
1 stop8h 21mMultiple Airlines
Sun 12/289:38 pmCLT - BOS
1 stop13h 12mMultiple Airlines
Deal found 12/15$260
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:44 pmBOS - SAV
1 stop7h 19mAmerican Airlines
Thu 1/15:05 amSAV - BOS
1 stop4h 49mAmerican Airlines
Deal found 12/15$262
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:20 amBOS - SAV
1 stop5h 23mUnited Airlines
Wed 12/317:22 pmSAV - BOS
1 stop4h 32mUnited Airlines
Deal found 12/16$263
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:56 amBOS - CHS
1 stop21h 41mMultiple Airlines
Mon 1/52:15 pmCHS - BOS
2 stops35h 04mMultiple Airlines
Deal found 12/17$264
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:30 amBOS - CLT
Nonstop2h 31mAmerican Airlines
Tue 12/301:05 pmCLT - BOS
1 stop6h 51mAmerican Airlines
Deal found 12/17$267
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:35 amBOS - CHS
Nonstop2h 47mDelta
Thu 1/18:05 amCHS - BOS
Nonstop2h 27mDelta
Deal found 12/17$267

Find flight deals from Maine to South Carolina

Keep the following information in mind while searching for Maine to South Carolina flight deals. Data was last updated December 18, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$127
(Delta)

One-way from

$37
(CheapOair)

Popular in

April

Cheapest in

January

Average price

$179

Good round-trip deal

$150 or less

Good one-way deal

$59 or less
Provider with most accurate pricing for Boston Logan Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Myrtle Beach Intl flights.
Search Deals
From Maine to South Carolina
Search Deals
One-way flight from Maine to South Carolina
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Maine to South Carolina.
Search Deals
Price to beat on a one-way flight from Maine to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Maine to South Carolina that are best for you.

Fly from

Maine

Fly to

South Carolina

Route

Depart

Return

Price

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Wed 1/28

11:05 am-2:04 pm

Nonstop2h 59m

Savannah/Hilton Head

Sun 2/1

2:47 pm-5:18 pm

Nonstop2h 31m

$137

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Wed 1/21

11:05 am-2:04 pm

Nonstop2h 59m

Savannah/Hilton Head

Tue 1/27

2:47 pm-5:18 pm

Nonstop2h 31m

$137

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Wed 1/14

11:05 am-2:04 pm

Nonstop2h 59m

Savannah/Hilton Head

Wed 1/21

2:47 pm-5:18 pm

Nonstop2h 31m

$137

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Sat 2/7

11:05 am-2:04 pm

Nonstop2h 59m

Savannah/Hilton Head

Wed 2/11

2:47 pm-5:18 pm

Nonstop2h 31m

$137

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Wed 1/28

11:05 am-2:04 pm

Nonstop2h 59m

Savannah/Hilton Head

Tue 2/10

2:47 pm-5:18 pm

Nonstop2h 31m

$137

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Mon 1/26

11:05 am-2:04 pm

Nonstop2h 59m

Savannah/Hilton Head

Thu 1/29

2:47 pm-5:18 pm

Nonstop2h 31m

$139

BostonCharleston

BOS - CHS

BOSCHS

Boston Logan Intl

Thu 1/15

12:55 pm-3:40 pm

Nonstop2h 45m

Charleston

Sun 1/18

5:25 am-10:02 am

1 stop4h 37m

$141

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Tue 2/3

9:15 am-12:09 pm

Nonstop2h 54m

Savannah/Hilton Head

Thu 2/5

1:10 pm-3:38 pm

Nonstop2h 28m

$147

BostonCharleston

BOS - CHS

BOSCHS

Boston Logan Intl

Fri 1/9

8:30 am-11:13 am

Nonstop2h 43m

Charleston

Fri 1/16

12:09 pm-2:25 pm

Nonstop2h 16m

$147

BostonCharleston

BOS - CHS

BOSCHS

Boston Logan Intl

Mon 1/12

8:30 am-11:13 am

Nonstop2h 43m

Charleston

Wed 1/14

12:09 pm-2:25 pm

Nonstop2h 16m

$147

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 60 results
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Best time to book a flight from Maine to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to South Carolina

What is the cheapest month to book a flight from Maine to South Carolina?

Currently, March is the cheapest month in which you can book a flight from Maine to South Carolina (average of $88). Flying from Maine to South Carolina in December is currently the most expensive (average of $153). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ME to SC?

Find hourly flight availability from Maine to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from Maine to South Carolina in the evening. By choosing this option you can save up to 66% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 18, 2025.
Get a feel of what it's like to fly with Breeze Airways, Southwest, and Delta from Maine to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Overall

8.2

Comfort

8.2

Crew

8.8

Entertainment

6.7

Boarding

8.4

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Breeze Airways
8.2
Very good
248 reviews
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Overall

8.2

Comfort

8.2

Crew

8.8

Entertainment

6.7

Boarding

8.4

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Southwest
7.9
Good
4,250 reviews
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Overall

8.2

Comfort

8.2

Crew

8.8

Entertainment

6.7

Boarding

8.4

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Delta
7.9
Good
8,008 reviews
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Overall

8.2

Comfort

8.2

Crew

8.8

Entertainment

6.7

Boarding

8.4

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
United Airlines
7.4
Good
9,093 reviews
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Overall

8.2

Comfort

8.2

Crew

8.8

Entertainment

6.7

Boarding

8.4

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
American Airlines
7.2
Good
11,055 reviews
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Overall

8.2

Comfort

8.2

Crew

8.8

Entertainment

6.7

Boarding

8.4

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.

Related info for your journey

Find useful and relevant information for your journey from Maine to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Maine to South Carolina flight route?

    The Maine to South Carolina flight path was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Maine to South Carolina?

    A quick flight from Maine to South Carolina can take about 2h 43m. Delta provides one of the quickest options available for as low as $147. There are 818 mi between Maine and South Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Maine to South Carolina one-way?

    $182 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $197 and $237, respectively.

  • Can I find deals for flights from Maine to South Carolina that include hotel bookings?

    Yes. In addition to deals on Maine to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to South Carolina.

  • Can I find deals for business class flights from Maine to South Carolina?

    Yes. Cheapflights offers flight deals from Maine to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to South Carolina?

    Currently, March is the cheapest month in which you can book a flight from Maine to South Carolina (average of $88). Flying from Maine to South Carolina in December is currently the most expensive (average of $153). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Maine to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Maine to South Carolina

Discover the top 5 airlines that operate flights from Maine to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$90Average$173FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$148Average$351FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$236Average$432FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$236Average$410FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$296Average$386FlexibilityNo cancel feeOn-time69%

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