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South Carolina

$34+ Cheap flights from Maine to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — CHS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Maine to South Carolina

Cheapest flights from Maine to South Carolina
Explore the most affordable flight options available from Maine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/29:57 am
BOS
-
MYR
Nonstop2h 28m
Spirit Airlines
Tue 3/101:20 pm
MYR
-
BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28$96
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/259:57 am
BOS
-
MYR
Nonstop2h 28m
Spirit Airlines
Tue 3/31:20 pm
MYR
-
BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/27$97
This Super.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:29 pm
BOS
-
MYR
Nonstop2h 19m
Spirit Airlines
Wed 3/256:37 pm
MYR
-
BOS
1 stop5h 22m
Spirit Airlines
Deal found 1/27$98
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:57 am
BOS
-
MYR
Nonstop2h 28m
Spirit Airlines
Thu 2/261:20 pm
MYR
-
BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28$101
This Cheapflightsfares deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:57 am
BOS
-
MYR
Nonstop2h 28m
Spirit Airlines
Mon 3/21:20 pm
MYR
-
BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28$102
This Priceline deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:39 pm
BOS
-
MYR
Nonstop2h 25m
Spirit Airlines
Sat 2/149:53 am
MYR
-
BOS
Nonstop1h 59m
Spirit Airlines
Deal found 1/28$103
This Cheapflightsfares deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/279:57 am
BOS
-
MYR
Nonstop2h 28m
Spirit Airlines
Fri 3/61:20 pm
MYR
-
BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28$104
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/179:57 am
BOS
-
MYR
Nonstop2h 28m
Spirit Airlines
Wed 2/251:20 pm
MYR
-
BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28$106
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/279:57 am
BOS
-
MYR
Nonstop2h 28m
Spirit Airlines
Mon 3/21:20 pm
MYR
-
BOS
Nonstop2h 07m
Spirit Airlines
Deal found 1/28$108
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:57 am
BOS
-
MYR
Nonstop2h 28m
Spirit Airlines
Thu 3/126:37 pm
MYR
-
BOS
1 stop5h 22m
Spirit Airlines
Deal found 1/28$109
This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:29 pm
BOS
-
MYR
Nonstop2h 19m
Spirit Airlines
Sat 4/1810:37 am
MYR
-
BOS
Nonstop2h 05m
Spirit Airlines
Deal found 1/27$110
This Priceline deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:57 am
BOS
-
MYR
Nonstop2h 28m
Spirit Airlines
Wed 2/259:09 am
MYR
-
BOS
1 stop8h 06m
Spirit Airlines
Deal found 1/28$111

Find flight deals from Maine to South Carolina

Keep the following information in mind while searching for Maine to South Carolina flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$96
(Kiwi.com)

One-way from

$34
(Priceline)

Popular in

April

Cheapest in

August

Average price

$370

Good round-trip deal

$163 or less

Good one-way deal

$81 or less
Provider with most accurate pricing for Portland-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Myrtle Beach Intl flights.
Search Deals
From Maine to South Carolina
Search Deals
One-way flight from Maine to South Carolina
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($21 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Maine to South Carolina.
Search Deals
Price to beat on a one-way flight from Maine to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Maine to South Carolina that are best for you.

Fly from

Maine

Fly to

South Carolina

Route

Depart

Return

Price

BostonMyrtle Beach

BOS - MYR

BOSMYR

Boston Logan Intl

Wed 4/8

5:40 am-5:39 pm

1 stop11h 59m

Myrtle Beach Intl

Mon 4/13

3:29 pm-5:33 pm

Nonstop2h 04m

$98

BostonMyrtle Beach

BOS - MYR

BOSMYR

Boston Logan Intl

Sat 3/7

6:10 pm-7:13 am

1 stop13h 03m

Myrtle Beach Intl

Fri 3/13

3:29 pm-5:33 pm

Nonstop2h 04m

$103

BostonMyrtle Beach

BOS - MYR

BOSMYR

Boston Logan Intl

Wed 2/18

6:00 am-8:39 pm

2 stops14h 39m

Myrtle Beach Intl

Wed 2/25

1:20 pm-3:27 pm

Nonstop2h 07m

$143

BostonMyrtle Beach

BOS - MYR

BOSMYR

Boston Logan Intl

Tue 3/10

9:57 am-12:25 pm

Nonstop2h 28m

Myrtle Beach Intl

Fri 3/13

6:37 pm-11:59 pm

1 stop5h 22m

$146

BostonMyrtle Beach

BOS - MYR

BOSMYR

Boston Logan Intl

Sun 4/19

6:33 pm-9:03 pm

Nonstop2h 30m

Myrtle Beach Intl

Thu 4/23

8:01 pm-10:04 pm

Nonstop2h 03m

$148

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Wed 3/4

1:20 pm-8:15 pm

1 stop6h 55m

Savannah/Hilton Head

Mon 3/9

7:45 pm-12:05 am

1 stop4h 20m

$151

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Tue 3/3

1:20 pm-8:15 pm

1 stop6h 55m

Savannah/Hilton Head

Mon 3/9

7:45 pm-12:05 am

1 stop4h 20m

$151

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Mon 3/2

2:45 pm-8:50 pm

1 stop6h 05m

Savannah/Hilton Head

Sat 3/7

2:15 pm-11:05 pm

1 stop8h 50m

$156

BostonCharleston

BOS - CHS

BOSCHS

Boston Logan Intl

Sat 2/28

2:10 pm-10:05 pm

1 stop7h 55m

Charleston

Wed 3/4

7:55 am-5:10 pm

2 stops9h 15m

$156

BostonSavannah

BOS - SAV

BOSSAV

Boston Logan Intl

Wed 2/25

12:05 pm-3:00 pm

Nonstop2h 55m

Savannah/Hilton Head

Wed 3/4

3:41 pm-6:10 pm

Nonstop2h 29m

$157

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 60 results
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Best time to book a flight from Maine to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to South Carolina

What is the cheapest month to book a flight from Maine to South Carolina?

Currently, April is the cheapest month in which you can book a flight from Maine to South Carolina (average of $85). Flying from Maine to South Carolina in October is currently the most expensive (average of $142). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ME to SC?

Find hourly flight availability from Maine to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

It’s optimal to fly from Maine to South Carolina at noon. By choosing this option you can save up to 63% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with Breeze Airways, Southwest, and Delta from Maine to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
263 reviews

Overall

8.2

Crew

8.7

Comfort

8.2

Boarding

8.3

Entertainment

6.6

Food

6.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.2
Very good
263 reviews
Breeze Airways
8.2
Very good
263 reviews

Overall

8.2

Crew

8.7

Comfort

8.2

Boarding

8.3

Entertainment

6.6

Food

6.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Southwest
8.0
Very good
4,267 reviews
Breeze Airways
8.2
Very good
263 reviews

Overall

8.2

Crew

8.7

Comfort

8.2

Boarding

8.3

Entertainment

6.6

Food

6.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Delta
7.9
Good
8,127 reviews
Breeze Airways
8.2
Very good
263 reviews

Overall

8.2

Crew

8.7

Comfort

8.2

Boarding

8.3

Entertainment

6.6

Food

6.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
American Airlines
7.2
Good
11,206 reviews
Breeze Airways
8.2
Very good
263 reviews

Overall

8.2

Crew

8.7

Comfort

8.2

Boarding

8.3

Entertainment

6.6

Food

6.7

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Maine to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Maine to South Carolina flight route?

    The Maine to South Carolina flight path was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Maine to South Carolina?

    A quick flight from Maine to South Carolina can take about 2h 55m. Spirit Airlines provides one of the quickest options available for as low as $157. There are 901 mi between Maine and South Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Maine to South Carolina one-way?

    $182 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $197 and $237, respectively.

  • Can I find deals for flights from Maine to South Carolina that include hotel bookings?

    Yes. In addition to deals on Maine to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to South Carolina.

  • Can I find deals for business class flights from Maine to South Carolina?

    Yes. Cheapflights offers flight deals from Maine to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to South Carolina?

    Currently, April is the cheapest month in which you can book a flight from Maine to South Carolina (average of $85). Flying from Maine to South Carolina in October is currently the most expensive (average of $142). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Maine to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Maine to South Carolina

Discover the top 4 airlines that operate flights from Maine to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$90Average$170FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$147Average$324FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$236Average$430FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$236Average$392FlexibilityNo cancel feeOn-time71%

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