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South Carolina

$59+ Cheap flights from Louisville (SDF) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CHS
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from Louisville to South Carolina

Keep the following information in mind while searching for Louisville to South Carolina flight deals. Data was last updated August 20, 2025.

Round-trip from

$88
(Breeze Airways)

One-way from

$59
(Breeze Airways)

Popular in

February

Cheapest in

March

Average price

$232

Good round-trip deal

$91 or less

Good one-way deal

$49 or less
From Louisville Intl to South Carolina
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One-way flight from Louisville Intl to South Carolina
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Highest demand for flights based on searches. 2% potential increase in price ($6 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Louisville Intl to South Carolina.
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Price to beat on a one-way flight from Louisville Intl to South Carolina.
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Find flight deals from Louisville to South Carolina

Cheapest flights from Louisville to South Carolina
Explore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Breeze Airways deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/58:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Mon 9/87:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 8/18$88
This Breeze Airways deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/88:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Mon 9/157:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 8/18$93
This Breeze Airways deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/38:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Mon 10/67:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 8/19$99
This Orbitz deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/58:52 pmSDF - CHS
Nonstop1h 36mMultiple Airlines
Mon 9/810:10 amCHS - SDF
1 stop11h 54mMultiple Airlines
Deal found 8/18$123
This Expedia deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/68:23 amSDF - MYR
1 stop11h 43mSpirit Airlines
Sat 9/134:23 pmMYR - SDF
1 stop5h 41mSpirit Airlines
Deal found 8/18$124
This Expedia deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/278:52 pmSDF - CHS
Nonstop1h 36mMultiple Airlines
Fri 10/3110:31 amCHS - SDF
1 stop7h 32mMultiple Airlines
Deal found 8/18$131
This Breeze Airways deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/228:35 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Mon 8/257:05 amCHS - SDF
Nonstop1h 47mBreeze Airways
Deal found 8/18$134
This Mytrip deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/58:23 amSDF - MYR
1 stop11h 43mSpirit Airlines
Sat 9/204:23 pmMYR - SDF
1 stop5h 41mSpirit Airlines
Deal found 8/19$143
This Priceline deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/128:52 pmSDF - CHS
Nonstop1h 36mMultiple Airlines
Sun 9/1412:08 pmCHS - SDF
1 stop9h 56mMultiple Airlines
Deal found 8/19$153
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/205:50 amSDF - CHS
1 stop4h 15mSouthwest
Wed 9/248:35 amCHS - SDF
1 stop4h 00mSouthwest
Deal found 8/18$157
This Priceline deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2510:14 amSDF - MYR
1 stop6h 11mSpirit Airlines
Sat 9/274:23 pmMYR - SDF
1 stop5h 41mSpirit Airlines
Deal found 8/18$169
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/98:23 amSDF - MYR
1 stop11h 43mSpirit Airlines
Fri 9/127:17 pmMYR - SDF
1 stop14h 02mSpirit Airlines
Deal found 8/18$173

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Louisville to South Carolina that are best for you.

Fly from

Louisville

Fly to

South Carolina

Route

Depart

Return

Price

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Fri 9/5

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Mon 9/8

7:05 am-8:58 am

Nonstop1h 53m

$88

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Mon 10/27

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Fri 10/31

7:05 am-8:58 am

Nonstop1h 53m

$93

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Mon 9/8

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Mon 9/15

7:05 am-8:58 am

Nonstop1h 53m

$93

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Fri 10/3

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Mon 10/6

7:05 am-8:58 am

Nonstop1h 53m

$99

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Fri 9/12

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Fri 9/19

7:05 am-8:58 am

Nonstop1h 53m

$99

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Mon 9/8

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Thu 9/11

12:08 pm-10:04 pm

1 stop9h 56m

$123

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Fri 9/5

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Mon 9/8

10:10 am-10:04 pm

1 stop11h 54m

$123

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Tue 9/16

8:23 am-8:06 pm

1 stop11h 43m

Myrtle Beach Intl

Sat 9/20

4:23 pm-10:04 pm

1 stop5h 41m

$124

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Sat 9/6

8:23 am-8:06 pm

1 stop11h 43m

Myrtle Beach Intl

Sat 9/13

4:23 pm-10:04 pm

1 stop5h 41m

$124

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Mon 10/27

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Fri 10/31

10:31 am-6:03 pm

1 stop7h 32m

$131

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Showing 1-10 of 60 results
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Best time to book a flight from Louisville to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to South Carolina

What is the cheapest month to book a flight from Louisville to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $217). Flying from Louisville to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to SC?

Find hourly flight availability from Louisville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Louisville to South Carolina as you normally would.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 20, 2025.
Get a feel of what it's like to fly with Southwest, Breeze Airways, and Delta from Louisville to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Breeze Airways
8.0
Very good
197 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,982 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Spirit Airlines
6.3
Okay
8,039 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Louisville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to South Carolina?

    Most people fly from Louisville Intl (SDF) if they book a flight from Louisville to South Carolina. Louisville Intl is conveniently located just 5.3 mi from Louisville’s city center.

  • How popular is this Louisville to South Carolina flight route?

    The Louisville Intl to South Carolina flight path was viewed by 4 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Louisville to South Carolina?

    A quick flight from Louisville to South Carolina can take about 1h 36m. Breeze Airways provides one of the quickest options available for as low as $88. The distance from Louisville to South Carolina is about 485 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Louisville to South Carolina one-way?

    For one-way options, check prices for Breeze Airways. According to our data, you can fly for as low as $59. Users have also found prices from $60 and $89 on Spirit Airlines and American Airlines, respectively.

  • What are the most popular routes from Louisville to South Carolina?

    The most popular flight routes from Louisville to South Carolina are Louisville Intl - Savannah/Hilton Head, Louisville Intl - Charleston and Louisville Intl - Myrtle Beach Intl.

  • What are the cheapest flights from Louisville to South Carolina?

    Looking for the cheapest flight from Louisville to South Carolina? While on average our users pay $78, our data indicates the cheapest price to be $41. The most popular route (Louisville Intl - Savannah/Hilton Head), is priced around $192.

  • Can I find deals for flights from Louisville to South Carolina that include hotel bookings?

    Yes. In addition to deals on Louisville to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to South Carolina.

  • Can I find deals for business class flights from Louisville to South Carolina?

    Yes. Cheapflights offers flight deals from Louisville to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $217). Flying from Louisville to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Louisville to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Louisville to South Carolina

Discover the top 7 airlines that operate flights from Louisville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$77Average$140FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$87Average$181FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$88Average$133FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$148Average$430FlexibilityNo cancel feeOn-time69%
DeltaCheapest$153Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$190Average$363FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$219Average$353FlexibilityNo cancel feeOn-time63%

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