$43+ Cheap flights from Louisville (SDF) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/20. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CHS
Jul 14 — Jul 211
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to South Carolina with Cheapflights
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Cheapest flights from Louisville to South CarolinaExplore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2026.
Explore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2026.
This Trip.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/110:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 6/14![Allegiant Air logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/110:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 6/13![Allegiant Air logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:11 pm
SDF
- MYR
Nonstop1h 32m
Allegiant Air
Sat 8/1510:39 am
MYR
- SDF
Nonstop1h 42m
Allegiant Air
Deal found 6/12![Allegiant Air logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/124:52 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 7/198:30 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:29 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 8/99:00 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 6/12![Allegiant Air logo]()
$81
This Trip.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1611:28 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 7/198:30 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 6/12![Allegiant Air logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:28 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 7/99:00 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/124:52 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 7/169:00 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 6/13![Allegiant Air logo]()
$90
This Gotogate deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:45 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 8/166:16 pm
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 6/12![Allegiant Air logo]()
$96
This Super.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 8/287:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 7/1110:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 6/13![Allegiant Air logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 8/147:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 6/13![Breeze Airways logo]()
$107
Best flights from Louisville to South CarolinaDiscover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 14, 2026.
Discover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 14, 2026.
This Breeze Airways deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 8/283:54 pm
CHS
- SDF
1 stop4h 54m
Breeze Airways
Deal found 6/9![Breeze Airways logo]()
$159
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:05 am
SDF
- SAV
1 stop4h 35m
Delta
Wed 9/26:35 am
SAV
- SDF
1 stop3h 57m
Delta
Deal found 6/9![Delta logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:39 am
SDF
- GSP
1 stop7h 12m
Multiple Airlines
Sun 8/307:51 pm
GSP
- SDF
1 stop24h 57m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$257
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:19 pm
SDF
- CAE
1 stop3h 51m
American Airlines
Mon 7/208:30 pm
CAE
- SDF
1 stop4h 04m
American Airlines
Deal found 6/13![American Airlines logo]()
$280
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:00 am
SDF
- MYR
2 stops10h 40m
Southwest
Mon 8/101:55 pm
MYR
- SDF
2 stops6h 35m
Southwest
Deal found 6/10![Southwest logo]()
$283
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
SDF
- SAV
2 stops8h 16m
United Airlines
Fri 8/2812:59 pm
SAV
- SDF
1 stop6h 08m
United Airlines
Deal found 6/12![United Airlines logo]()
$315
This Super.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:59 pm
SDF
- CHS
Nonstop1h 35m
Breeze Airways
Fri 10/166:10 am
CHS
- SDF
Nonstop1h 52m
Breeze Airways
Deal found 6/13![Breeze Airways logo]()
$188
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:05 am
SDF
- SAV
1 stop3h 35m
Delta
Tue 9/18:06 am
SAV
- SDF
1 stop4h 20m
Delta
Deal found 6/9![Delta logo]()
$237
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:50 pm
SDF
- CHS
1 stop6h 09m
Delta
Fri 8/286:15 am
CHS
- SDF
1 stop6h 06m
Delta
Deal found 6/13![Delta logo]()
$237
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:19 pm
SDF
- CAE
1 stop3h 51m
American Airlines
Sat 7/114:58 pm
CAE
- SDF
1 stop5h 06m
American Airlines
Deal found 6/9![American Airlines logo]()
$285
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:10 am
SDF
- SAV
2 stops7h 28m
United Airlines
Sun 8/1612:59 pm
SAV
- SDF
1 stop6h 08m
United Airlines
Deal found 6/12![United Airlines logo]()
$315
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:45 am
SDF
- CHS
2 stops8h 20m
Southwest
Sun 11/156:35 am
CHS
- SDF
1 stop5h 35m
Southwest
Deal found 6/11![Southwest logo]()
$319
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
SDF
- CAE
1 stop3h 22m
Delta
Tue 7/213:51 pm
CAE
- SDF
1 stop3h 22m
Delta
Deal found 6/13![Delta logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:48 pm
SDF
- GSP
2 stops18h 18m
Multiple Airlines
Sun 7/193:51 pm
GSP
- SDF
1 stop22h 16m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:01 am
SDF
- HHH
1 stop4h 26m
American Airlines
Tue 6/305:21 pm
HHH
- SDF
1 stop5h 06m
American Airlines
Deal found 6/11![American Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:45 am
SDF
- SAV
2 stops9h 30m
Southwest
Sun 8/97:15 am
SAV
- SDF
1 stop6h 55m
Southwest
Deal found 6/10![Southwest logo]()
$321
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:15 am
SDF
- CAE
2 stops7h 01m
United Airlines
Sat 7/1110:31 am
CAE
- SDF
1 stop4h 06m
United Airlines
Deal found 6/9![United Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:05 am
SDF
- CAE
1 stop5h 57m
Delta
Sun 7/57:41 pm
CAE
- SDF
1 stop4h 51m
Delta
Deal found 6/13![Delta logo]()
$280
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:05 am
SDF
- SAV
1 stop4h 38m
United Airlines
Sat 7/1112:10 pm
SAV
- SDF
1 stop7h 08m
United Airlines
Deal found 6/12![United Airlines logo]()
$330
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/22:30 pm
SDF
- CLT
1 stop7h 15m
Southwest
Wed 8/512:35 pm
CLT
- SDF
2 stops8h 00m
Southwest
Deal found 6/9![Southwest logo]()
$331
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:10 am
SDF
- CAE
1 stop4h 49m
Delta
Tue 8/410:04 am
CAE
- SDF
1 stop4h 14m
Delta
Deal found 6/11![Delta logo]()
$280
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:00 am
SDF
- CAE
1 stop4h 09m
American Airlines
Tue 7/286:03 pm
CAE
- SDF
1 stop6h 31m
American Airlines
Deal found 6/12![American Airlines logo]()
$353
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:45 am
SDF
- SAV
2 stops10h 50m
Southwest
Mon 9/76:50 am
SAV
- SDF
1 stop6h 15m
Southwest
Deal found 6/12![Southwest logo]()
$331
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:05 am
SDF
- CAE
1 stop3h 51m
Delta
Sun 7/55:35 am
CAE
- SDF
1 stop4h 55m
Delta
Deal found 6/12![Delta logo]()
$280
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:13 pm
SDF
- GSP
1 stop6h 32m
United Airlines
Wed 8/192:18 pm
GSP
- SDF
1 stop4h 49m
United Airlines
Deal found 6/12![United Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:19 pm
SDF
- AGS
1 stop3h 35m
American Airlines
Wed 7/156:31 pm
AGS
- SDF
1 stop6h 03m
American Airlines
Deal found 6/10![American Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:05 pm
SDF
- MYR
1 stop3h 20m
Southwest
Fri 8/71:55 pm
MYR
- SDF
2 stops6h 35m
Southwest
Deal found 6/11![Southwest logo]()
$337
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
SDF
- CAE
1 stop3h 56m
United Airlines
Tue 8/42:51 pm
CAE
- SDF
2 stops8h 04m
United Airlines
Deal found 6/11![United Airlines logo]()
$352
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:17 pm
SDF
- SAV
1 stop5h 37m
Delta
Sun 8/307:59 pm
SAV
- SDF
1 stop4h 35m
Delta
Deal found 6/10![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:35 pm
SDF
- CHS
1 stop7h 30m
Southwest
Mon 10/51:15 pm
CHS
- SDF
2 stops9h 05m
Southwest
Deal found 6/9![Southwest logo]()
$340
Last-minute flights from Louisville to South CarolinaDiscover last-minute flight deals from Louisville to South Carolina. Data last updated June 14, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to South Carolina. Data last updated June 14, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 7/37:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:28 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 7/99:00 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/110:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 6/13![Allegiant Air logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 7/1110:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 6/13![Allegiant Air logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Mon 7/137:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 6/13![Breeze Airways logo]()
$133
This Super.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Mon 7/137:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/124:52 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 7/198:30 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/124:52 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 7/169:00 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 6/13![Allegiant Air logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 7/177:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1611:28 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 7/198:30 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/181:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 7/2510:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 6/12![Allegiant Air logo]()
$139
This Trip.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/110:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 6/14![Allegiant Air logo]()
$66
One-way flights from Louisville to South CarolinaSearch for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 14, 2026.
Search for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/201:06 pm
SDF
- MYR
Nonstop1h 32m
Allegiant Air
Deal found 6/11![Allegiant Air logo]()
$43
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1611:28 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Deal found 6/11![Allegiant Air logo]()
$46
This Breeze Airways deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$54
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$58
This Breeze Airways deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$63
This Breeze Airways deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:10 pm
SDF
- CLT
1 stop24h 03m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/109:10 pm
SDF
- CLT
1 stop24h 03m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$92
Find flight deals from Louisville to South Carolina
Keep the following information in mind while searching for Louisville to South Carolina flight deals. Data was last updated June 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $66 (Trip.com) |
One-way from | $43 (Kiwi.com) |
Popular in | January |
Cheapest in | July |
Average price | $196 |
Good round-trip deal | $110 or less |
Good one-way deal | $59 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
Use the filters below to find and compare flights from Louisville to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Mon 8/24
8:28 pm-10:06 pm
Nonstop1h 38m
Charleston
Fri 8/28
3:54 pm-8:48 pm
1 stop4h 54m
$159
Quickest round-trip
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Mon 10/12
7:59 pm-9:34 pm
Nonstop1h 35m
Charleston
Fri 10/16
6:10 am-8:02 am
Nonstop1h 52m
$188
LouisvilleSavannah
SDF - SAV
SDFSAV
Louisville Intl
Wed 8/26
7:05 am-11:40 am
1 stop4h 35m
Savannah/Hilton Head
Wed 9/2
6:35 am-10:32 am
1 stop3h 57m
$237
LouisvilleSavannah
SDF - SAV
SDFSAV
Louisville Intl
Tue 8/25
8:05 am-11:40 am
1 stop3h 35m
Savannah/Hilton Head
Tue 9/1
8:06 am-12:26 pm
1 stop4h 20m
$237
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Mon 8/24
5:50 pm-11:59 pm
1 stop6h 09m
Charleston
Fri 8/28
6:15 am-12:21 pm
1 stop6h 06m
$237
LouisvilleGreenville
SDF - GSP
SDFGSP
Louisville Intl
Fri 8/28
10:39 am-5:51 pm
1 stop7h 12m
Greenville
Sun 8/30
7:51 pm-8:48 pm
1 stop24h 57m
$257
LouisvilleColumbia
SDF - CAE
SDFCAE
Louisville Intl
Tue 7/14
6:00 am-9:22 am
1 stop3h 22m
Columbia Metropolitan
Tue 7/21
3:51 pm-7:13 pm
1 stop3h 22m
$271
LouisvilleColumbia
SDF - CAE
SDFCAE
Louisville Intl
Sat 7/18
8:19 pm-12:10 am
1 stop3h 51m
Columbia Metropolitan
Mon 7/20
8:30 pm-12:34 am
1 stop4h 04m
$280
LouisvilleColumbia
SDF - CAE
SDFCAE
Louisville Intl
Fri 7/3
7:05 am-1:02 pm
1 stop5h 57m
Columbia Metropolitan
Sun 7/5
7:41 pm-12:32 am
1 stop4h 51m
$280
LouisvilleColumbia
SDF - CAE
SDFCAE
Louisville Intl
Thu 7/23
8:10 am-12:59 pm
1 stop4h 49m
Columbia Metropolitan
Tue 8/4
10:04 am-2:18 pm
1 stop4h 14m
$280
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Louisville to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Louisville with our price prediction graph.
SDF-MYR
SDF-SAV
SDF-CHS
SDF-CLT
SDF-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to South Carolina
SDF-USSC
SDF-MYR
SDF-SAV
SDF-CHS
SDF-CLT
What is the cheapest month to book a flight from Louisville to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $37). Flying from Louisville to South Carolina in April is currently the most expensive (average of $274). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SDF to SC?
Find hourly flight availability from Louisville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 14, 2026.
A simple way to save on the total cost of your ticket is to fly from Louisville to South Carolina in the morning. If you’re flexible enough to do this you can expect to save up to 69% on your trip compared to booking a flight at noon.
How much does it cost to fly round-trip from Louisville to South Carolina?
How far ahead should I book a flight from Louisville to South Carolina?
To ensure you get the cheapest price possible for a flight from Louisville to South Carolina, you should look to book at least 39 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 14, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Louisville to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Overall
8.2
Crew
8.8
Comfort
8.2
Boarding
8.3
Entertainment
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Overall
8.2
Crew
8.8
Comfort
8.2
Boarding
8.3
Entertainment
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Overall
8.2
Crew
8.8
Comfort
8.2
Boarding
8.3
Entertainment
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Overall
8.2
Crew
8.8
Comfort
8.2
Boarding
8.3
Entertainment
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Overall
8.2
Crew
8.8
Comfort
8.2
Boarding
8.3
Entertainment
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Overall
8.2
Crew
8.8
Comfort
8.2
Boarding
8.3
Entertainment
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Louisville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Louisville to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to South Carolina by cabin class
Find flights from Louisville to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and South Carolina flights
Browse other Louisville and South Carolina flight options. Last updated on June 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisville to South Carolina flights
Consider these flights traveling from Louisville to South Carolina.
Top 6 airlines flying from Louisville to South Carolina
Discover the top 6 airlines that operate flights from Louisville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$69 | Average$135 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$87 | Average$134 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$118 | Average$345 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$148 | Average$356 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$196 | Average$359 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$219 | Average$386 | FlexibilityNo cancel fee | On-time63% |