$49+ Cheap flights from Louisville (SDF) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CHS
Jun 17 — Jun 241
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to South Carolina with Cheapflights
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Cheapest flights from Louisville to South CarolinaExplore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
Explore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
This Trip.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:10 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Thu 7/99:00 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 5/17![Allegiant Air logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:10 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Thu 6/188:45 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 5/17![Allegiant Air logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/11:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/1510:39 am
MYR
- SDF
Nonstop1h 42m
Allegiant Air
Deal found 5/17![Allegiant Air logo]()
$82
This Mytrip deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:29 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 8/99:00 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 5/15![Allegiant Air logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/78:56 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Thu 6/188:45 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 5/15![Allegiant Air logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:10 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Sun 6/218:45 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 5/15![Allegiant Air logo]()
$104
This Mytrip deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/110:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 5/13![Allegiant Air logo]()
$106
This FlightHub deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/124:52 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 7/198:30 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 5/15![Allegiant Air logo]()
$106
This Mytrip deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 9/47:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 5/17![Breeze Airways logo]()
$106
This Mytrip deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 6/127:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 5/13![Breeze Airways logo]()
$108
This Mytrip deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 6/197:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 5/14![Breeze Airways logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:59 pm
SDF
- CHS
Nonstop1h 35m
Breeze Airways
Mon 9/286:10 am
CHS
- SDF
Nonstop1h 52m
Breeze Airways
Deal found 5/14![Breeze Airways logo]()
$113
Best flights from Louisville to South CarolinaDiscover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
Discover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
This Breeze Airways deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 6/193:54 pm
CHS
- SDF
1 stop4h 54m
Breeze Airways
Deal found 5/13![Breeze Airways logo]()
$208
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:20 am
SDF
- CHS
1 stop7h 15m
Southwest
Fri 5/297:00 pm
CHS
- SDF
1 stop4h 45m
Southwest
Deal found 5/17![Southwest logo]()
$237
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:34 pm
SDF
- CHS
1 stop4h 09m
Delta
Fri 7/39:41 am
CHS
- SDF
1 stop5h 50m
Delta
Deal found 5/16![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/99:00 am
SDF
- HHH
1 stop5h 21m
United Airlines
Wed 7/153:05 pm
HHH
- SDF
1 stop5h 18m
United Airlines
Deal found 5/14![United Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:10 pm
SDF
- GSP
1 stop4h 48m
American Airlines
Wed 7/296:18 pm
GSP
- SDF
1 stop6h 16m
American Airlines
Deal found 5/16![American Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2310:00 am
SDF
- HHH
1 stop5h 29m
Delta
Mon 7/2712:11 pm
HHH
- SDF
1 stop5h 38m
Delta
Deal found 5/14![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:50 am
SDF
- MYR
2 stops8h 30m
Southwest
Tue 9/85:05 pm
MYR
- SDF
1 stop4h 25m
Southwest
Deal found 5/17![Southwest logo]()
$300
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:00 am
SDF
- MYR
1 stop3h 59m
United Airlines
Sat 6/1310:34 am
MYR
- SDF
1 stop4h 03m
United Airlines
Deal found 5/14![United Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:26 pm
SDF
- CAE
1 stop5h 28m
American Airlines
Sat 6/136:00 am
CAE
- SDF
1 stop4h 35m
American Airlines
Deal found 5/17![American Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1610:00 am
SDF
- MYR
1 stop5h 29m
Delta
Tue 6/236:00 am
MYR
- SDF
1 stop5h 53m
Delta
Deal found 5/13![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:25 pm
SDF
- GSP
1 stop4h 35m
Southwest
Wed 7/297:00 am
GSP
- SDF
1 stop5h 05m
Southwest
Deal found 5/16![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
SDF
- CAE
1 stop3h 25m
Delta
Mon 6/227:41 pm
CAE
- SDF
1 stop4h 51m
Delta
Deal found 5/15![Delta logo]()
$301
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:28 am
SDF
- HHH
1 stop6h 54m
American Airlines
Sun 8/92:48 pm
HHH
- SDF
1 stop4h 37m
American Airlines
Deal found 5/16![American Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:05 pm
SDF
- MYR
1 stop4h 35m
Southwest
Mon 6/157:50 am
MYR
- SDF
1 stop4h 40m
Southwest
Deal found 5/13![Southwest logo]()
$311
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
SDF
- CAE
1 stop3h 31m
Delta
Thu 6/185:35 am
CAE
- SDF
1 stop3h 22m
Delta
Deal found 5/14![Delta logo]()
$301
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:50 pm
SDF
- GSP
1 stop7h 28m
United Airlines
Wed 9/306:20 am
GSP
- SDF
1 stop6h 55m
United Airlines
Deal found 5/15![United Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:01 am
SDF
- HHH
1 stop4h 26m
American Airlines
Sat 6/64:24 pm
HHH
- SDF
1 stop4h 11m
American Airlines
Deal found 5/16![American Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:00 pm
SDF
- SAV
1 stop3h 35m
Southwest
Mon 9/76:50 am
SAV
- SDF
1 stop6h 15m
Southwest
Deal found 5/16![Southwest logo]()
$321
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:08 am
SDF
- CAE
1 stop4h 03m
Delta
Sat 6/65:50 pm
CAE
- SDF
1 stop6h 09m
Delta
Deal found 5/13![Delta logo]()
$301
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:04 am
SDF
- HHH
1 stop6h 13m
American Airlines
Sun 7/2612:50 pm
HHH
- SDF
1 stop6h 41m
American Airlines
Deal found 5/13![American Airlines logo]()
$350
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:05 pm
SDF
- MYR
1 stop4h 35m
Southwest
Mon 6/157:50 am
MYR
- SDF
1 stop4h 40m
Southwest
Deal found 5/13![Southwest logo]()
$329
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:45 pm
SDF
- CHS
1 stop4h 34m
Delta
Mon 7/207:59 pm
CHS
- SDF
1 stop4h 27m
Delta
Deal found 5/16![Delta logo]()
$316
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:00 am
SDF
- CAE
1 stop3h 56m
United Airlines
Wed 6/176:25 am
CAE
- SDF
1 stop7h 10m
United Airlines
Deal found 5/13![United Airlines logo]()
$444
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:20 pm
SDF
- SAV
1 stop5h 10m
Southwest
Sun 10/186:40 am
SAV
- SDF
1 stop8h 55m
Southwest
Deal found 5/17![Southwest logo]()
$334
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:38 am
SDF
- CAE
2 stops6h 27m
American Airlines
Sat 6/611:10 am
CAE
- SDF
2 stops7h 05m
American Airlines
Deal found 5/13![American Airlines logo]()
$386
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:50 pm
SDF
- MYR
1 stop6h 08m
Delta
Wed 6/107:57 pm
MYR
- SDF
1 stop4h 35m
Delta
Deal found 5/15![Delta logo]()
$341
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:40 am
SDF
- GSP
2 stops10h 35m
Southwest
Wed 10/712:45 pm
GSP
- SDF
2 stops7h 45m
Southwest
Deal found 5/14![Southwest logo]()
$345
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:01 am
SDF
- HHH
1 stop4h 25m
American Airlines
Wed 6/311:40 am
HHH
- SDF
2 stops10h 39m
American Airlines
Deal found 5/15![American Airlines logo]()
$408
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:17 am
SDF
- SAV
1 stop6h 33m
Delta
Sun 8/95:35 am
SAV
- SDF
1 stop3h 11m
Delta
Deal found 5/15![Delta logo]()
$344
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1212:00 pm
SDF
- MYR
2 stops10h 45m
Southwest
Wed 6/177:05 pm
MYR
- SDF
1 stop4h 05m
Southwest
Deal found 5/16![Southwest logo]()
$346
Last-minute flights from Louisville to South CarolinaDiscover last-minute flight deals from Louisville to South Carolina. Data last updated May 18, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to South Carolina. Data last updated May 18, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 6/127:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 5/13![Breeze Airways logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/78:56 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Thu 6/188:45 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 5/15![Allegiant Air logo]()
$101
This Booking.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 6/127:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 5/14![Breeze Airways logo]()
$139
This Mytrip deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Mon 6/157:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 5/14![Breeze Airways logo]()
$119
This Mytrip deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 6/197:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 5/14![Breeze Airways logo]()
$124
This Trip.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:10 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Thu 7/99:00 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 5/17![Allegiant Air logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:10 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Thu 6/188:45 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 5/16![Allegiant Air logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:10 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Sun 6/218:45 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 5/15![Allegiant Air logo]()
$104
This Mytrip deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 6/197:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 5/15![Breeze Airways logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1811:14 am
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Sun 6/218:45 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 5/15![Allegiant Air logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:49 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Sun 6/288:45 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 5/13![Allegiant Air logo]()
$134
This Mytrip deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 7/37:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 5/16![Breeze Airways logo]()
$116
One-way flights from Louisville to South CarolinaSearch for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
Search for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
This Booking.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 5/17![Breeze Airways logo]()
$49
This Booking.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 5/15![Breeze Airways logo]()
$59
This Booking.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 5/16![Breeze Airways logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/911:28 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Deal found 5/17![Allegiant Air logo]()
$66
This Booking.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 5/14![Breeze Airways logo]()
$68
This Booking.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:35 am
SDF
- CHS
1 stop6h 27m
Breeze Airways
Deal found 5/14![Breeze Airways logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/131:06 pm
SDF
- MYR
Nonstop1h 32m
Allegiant Air
Deal found 5/14![Allegiant Air logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/109:10 pm
SDF
- CLT
1 stop14h 52m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/279:09 pm
SDF
- GSP
1 stop10h 20m
Allegiant Air
Deal found 5/14![Allegiant Air logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/289:23 pm
SDF
- GSP
1 stop10h 11m
Allegiant Air
Deal found 5/13![Allegiant Air logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/812:16 pm
SDF
- CLT
1 stop23h 46m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$116
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:05 pm
SDF
- CHS
1 stop4h 51m
American Airlines
Deal found 5/17![American Airlines logo]()
$119
Find flight deals from Louisville to South Carolina
Keep the following information in mind while searching for Louisville to South Carolina flight deals. Data was last updated May 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $75 (Trip.com) |
One-way from | $49 (Booking.com) |
Popular in | January |
Cheapest in | July |
Average price | $314 |
Good round-trip deal | $135 or less |
Good one-way deal | $59 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Louisville to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Mon 6/15
8:28 pm-10:06 pm
Nonstop1h 38m
Charleston
Fri 6/19
3:54 pm-8:48 pm
1 stop4h 54m
$208
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Wed 5/27
6:20 am-1:35 pm
1 stop7h 15m
Charleston
Fri 5/29
7:00 pm-11:45 pm
1 stop4h 45m
$237
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Mon 6/29
6:34 pm-10:43 pm
1 stop4h 09m
Charleston
Fri 7/3
9:41 am-3:31 pm
1 stop5h 50m
$237
LouisvilleHilton Head Island
SDF - HHH
SDFHHH
Louisville Intl
Thu 7/9
9:00 am-2:21 pm
1 stop5h 21m
Hilton Head Island
Wed 7/15
3:05 pm-8:23 pm
1 stop5h 18m
$286
LouisvilleHilton Head Island
SDF - HHH
SDFHHH
Louisville Intl
Thu 7/23
10:00 am-3:29 pm
1 stop5h 29m
Hilton Head Island
Mon 7/27
12:11 pm-5:49 pm
1 stop5h 38m
$289
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Tue 6/16
10:00 am-3:29 pm
1 stop5h 29m
Myrtle Beach Intl
Tue 6/23
6:00 am-11:53 am
1 stop5h 53m
$295
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Tue 9/1
10:50 am-7:20 pm
2 stops8h 30m
Myrtle Beach Intl
Tue 9/8
5:05 pm-9:30 pm
1 stop4h 25m
$300
LouisvilleColumbia
SDF - CAE
SDFCAE
Louisville Intl
Mon 6/15
6:00 am-9:25 am
1 stop3h 25m
Columbia Metropolitan
Mon 6/22
7:41 pm-12:32 am
1 stop4h 51m
$301
LouisvilleColumbia
SDF - CAE
SDFCAE
Louisville Intl
Fri 6/12
6:00 am-9:31 am
1 stop3h 31m
Columbia Metropolitan
Thu 6/18
5:35 am-8:57 am
1 stop3h 22m
$301
LouisvilleColumbia
SDF - CAE
SDFCAE
Louisville Intl
Wed 6/3
7:08 am-11:11 am
1 stop4h 03m
Columbia Metropolitan
Sat 6/6
5:50 pm-11:59 pm
1 stop6h 09m
$301
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Louisville to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Louisville with our price prediction graph.
SDF-CHS
SDF-HHH
SDF-GSP
SDF-MYR
SDF-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to South Carolina
SDF-USSC
SDF-CHS
SDF-HHH
SDF-GSP
SDF-MYR
How far ahead should I book a flight from Louisville to South Carolina?
To ensure you get the cheapest price possible for a flight from Louisville to South Carolina, you should look to book at least 40 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Louisville to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $37). Flying from Louisville to South Carolina in April is currently the most expensive (average of $274). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SDF to SC?
Find hourly flight availability from Louisville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 18, 2026.
A simple way to save on the total cost of your ticket is to fly from Louisville to South Carolina in the morning. If you’re flexible enough to do this you can expect to save up to 47% on your trip compared to booking a flight at noon.
How much does it cost to fly round-trip from Louisville to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 18, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Louisville to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.7
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.7
Entertainment
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.7
Entertainment
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.7
Entertainment
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.7
Entertainment
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.7
Entertainment
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Boarding
8.3
Comfort
8.2
Overall
8.1
Food
6.7
Entertainment
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Louisville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Louisville to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to South Carolina by cabin class
Find flights from Louisville to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and South Carolina flights
Browse other Louisville and South Carolina flight options. Last updated on May 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisville to South Carolina flights
Consider these flights traveling from Louisville to South Carolina.
Top 7 airlines flying from Louisville to South Carolina
Discover the top 7 airlines that operate flights from Louisville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$62 | Average$160 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$77 | Average$128 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$78 | Average$149 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$118 | Average$340 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$148 | Average$468 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$183 | Average$343 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$219 | Average$385 | FlexibilityNo cancel fee | On-time63% |