$33+ Cheap flights from Louisville (SDF) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CHS
Sep 10 — Sep 171
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to South Carolina
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Cheapest flights from Louisville to South CarolinaExplore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
Explore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:59 pm -
Nonstop1h 35m
Mon 9/216:10 am -
Nonstop1h 52m
Deal found 8/7![Breeze Airways logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:28 pm -
Nonstop1h 38m
Fri 8/287:00 am -
Nonstop1h 46m
Deal found 8/6![Breeze Airways logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:59 pm -
Nonstop1h 35m
Mon 11/26:10 am -
Nonstop1h 52m
Deal found 8/9![Breeze Airways logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:59 pm -
Nonstop1h 35m
Fri 10/306:10 am -
Nonstop1h 52m
Deal found 8/7![Breeze Airways logo]()
$107
This Breeze Airways deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:28 pm -
Nonstop1h 38m
Mon 8/317:00 am -
Nonstop1h 46m
Deal found 8/7![Breeze Airways logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:45 pm -
Nonstop1h 34m
Sun 8/166:16 pm -
Nonstop1h 39m
Deal found 8/8![Allegiant Air logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:59 pm -
Nonstop1h 35m
Mon 11/26:10 am -
Nonstop1h 52m
Deal found 8/9![Breeze Airways logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:59 pm -
Nonstop1h 35m
Mon 9/146:10 am -
Nonstop1h 52m
Deal found 8/10![Breeze Airways logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:59 pm -
Nonstop1h 35m
Mon 9/216:10 am -
Nonstop1h 52m
Deal found 8/8![Breeze Airways logo]()
$118
This Expedia deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:11 pm -
Nonstop1h 32m
Sat 8/1510:39 am -
Nonstop1h 42m
Deal found 8/6![Allegiant Air logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:45 pm -
Nonstop1h 34m
Sun 9/139:15 am -
1 stop25h 10m
Deal found 8/9![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:11 pm -
Nonstop1h 32m
Sat 8/294:21 pm -
1 stop18h 11m
Deal found 8/9![Multiple Airlines logo]()
$199
Best flights from Louisville to South CarolinaDiscover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
Discover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:50 am -
1 stop4h 15m
Sat 9/56:45 am -
1 stop5h 20m
Deal found 8/9![Southwest logo]()
$246
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:55 pm -
1 stop4h 04m
Mon 9/216:40 am -
1 stop3h 39m
Deal found 8/9![Delta logo]()
$257
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop4h 25m
Sat 10/3110:55 am -
1 stop6h 51m
Deal found 8/10![American Airlines logo]()
$271
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:15 am -
1 stop8h 01m
Fri 9/412:59 pm -
1 stop6h 16m
Deal found 8/10![United Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:55 pm -
1 stop3h 33m
Thu 10/110:54 am -
1 stop6h 16m
Deal found 8/10![Delta logo]()
$264
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:50 am -
2 stops7h 20m
Fri 8/287:00 am -
2 stops8h 30m
Deal found 8/6![Southwest logo]()
$267
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:30 am -
1 stop4h 26m
Mon 1/115:41 pm -
1 stop4h 28m
Deal found 8/10![United Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:20 pm -
1 stop6h 15m
Sat 9/56:45 am -
1 stop5h 20m
Deal found 8/10![Southwest logo]()
$280
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop4h 07m
Fri 9/116:00 am -
1 stop4h 19m
Deal found 8/6![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:39 pm -
1 stop6h 30m
Mon 9/76:00 am -
1 stop4h 40m
Deal found 8/10![American Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:45 am -
2 stops8h 50m
Fri 9/115:35 pm -
1 stop5h 05m
Deal found 8/7![Southwest logo]()
$284
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:15 pm -
1 stop5h 37m
Sat 9/1210:08 am -
1 stop7h 09m
Deal found 8/10![United Airlines logo]()
$318
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:17 am -
1 stop4h 15m
Wed 9/912:17 pm -
2 stops8h 59m
Deal found 8/8![Delta logo]()
$290
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop4h 37m
Fri 10/96:08 pm -
1 stop6h 00m
Deal found 8/9![American Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop5h 08m
Sat 11/215:35 pm -
1 stop6h 30m
Deal found 8/6![Delta logo]()
$293
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
1 stop4h 37m
Sat 10/106:13 pm -
1 stop5h 54m
Deal found 8/7![American Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:05 am -
2 stops10h 35m
Thu 9/245:35 pm -
1 stop5h 05m
Deal found 8/6![Southwest logo]()
$304
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:00 am -
2 stops7h 45m
Fri 11/611:35 am -
1 stop5h 27m
Deal found 8/10![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:55 pm -
1 stop3h 33m
Mon 9/286:56 pm -
1 stop5h 03m
Deal found 8/6![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:05 pm -
1 stop6h 20m
Sat 9/125:15 pm -
1 stop4h 10m
Deal found 8/7![Southwest logo]()
$307
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:28 am -
1 stop6h 49m
Tue 9/85:16 pm -
1 stop5h 55m
Deal found 8/7![American Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:15 am -
1 stop6h 59m
Tue 9/152:48 pm -
1 stop5h 44m
Deal found 8/10![United Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/223:43 pm -
1 stop5h 01m
Fri 9/255:25 am -
1 stop4h 54m
Deal found 8/6![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:50 am -
2 stops9h 40m
Thu 10/292:35 pm -
2 stops6h 30m
Deal found 8/7![Southwest logo]()
$308
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/812:20 pm -
1 stop4h 25m
Sat 12/125:25 pm -
1 stop6h 30m
Deal found 8/10![United Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop4h 37m
Sat 10/106:13 pm -
1 stop5h 54m
Deal found 8/6![American Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:00 am -
1 stop5h 38m
Sat 9/268:35 am -
1 stop3h 50m
Deal found 8/6![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:40 am -
1 stop4h 30m
Mon 12/147:05 am -
1 stop5h 10m
Deal found 8/6![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:00 am -
2 stops8h 07m
Wed 9/165:38 pm -
1 stop6h 18m
Deal found 8/10![United Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:04 am -
1 stop3h 26m
Sun 10/118:12 pm -
1 stop3h 56m
Deal found 8/8![American Airlines logo]()
$357
Last-minute flights from Louisville to South CarolinaDiscover last-minute flight deals from Louisville to South Carolina. Data last updated August 11, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to South Carolina. Data last updated August 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:45 pm -
Nonstop1h 34m
Sun 8/166:16 pm -
Nonstop1h 39m
Deal found 8/8![Allegiant Air logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:45 pm -
Nonstop1h 34m
Sun 9/139:15 am -
1 stop25h 10m
Deal found 8/9![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:11 pm -
Nonstop1h 32m
Sat 8/294:21 pm -
1 stop18h 11m
Deal found 8/9![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:11 pm -
Nonstop1h 32m
Wed 8/264:21 pm -
1 stop18h 11m
Deal found 8/9![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:11 pm -
Nonstop1h 32m
Fri 8/281:13 pm -
2 stops30h 53m
Deal found 8/9![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:11 pm -
Nonstop1h 32m
Thu 8/2712:01 pm -
1 stop21h 48m
Deal found 8/9![Multiple Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:28 pm -
Nonstop1h 38m
Mon 8/247:00 am -
Nonstop1h 46m
Deal found 8/7![Breeze Airways logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:28 pm -
Nonstop1h 38m
Fri 8/287:00 am -
Nonstop1h 46m
Deal found 8/6![Breeze Airways logo]()
$102
This Breeze Airways deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:28 pm -
Nonstop1h 38m
Mon 8/317:00 am -
Nonstop1h 46m
Deal found 8/7![Breeze Airways logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:59 pm -
Nonstop1h 35m
Mon 9/146:10 am -
Nonstop1h 52m
Deal found 8/10![Breeze Airways logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:59 pm -
Nonstop1h 35m
Mon 9/216:10 am -
Nonstop1h 52m
Deal found 8/8![Breeze Airways logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:59 pm -
Nonstop1h 35m
Mon 9/216:10 am -
Nonstop1h 52m
Deal found 8/7![Breeze Airways logo]()
$97
One-way flights from Louisville to South CarolinaSearch for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
Search for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:45 pm -
Nonstop1h 34m
Deal found 8/6![Allegiant Air logo]()
$33
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:59 pm -
Nonstop1h 35m
Deal found 8/6![Breeze Airways logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:28 pm -
Nonstop1h 38m
Deal found 8/7![Breeze Airways logo]()
$83
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:20 pm -
1 stop6h 35m
Deal found 8/10![Southwest logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:56 pm -
2 stops17h 42m
Deal found 8/10![Breeze Airways logo]()
$121
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:53 am -
1 stop5h 48m
Deal found 8/10![Delta logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:56 am -
2 stops21h 42m
Deal found 8/7![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:55 pm -
1 stop24h 44m
Deal found 8/7![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:09 pm -
1 stop14h 35m
Deal found 8/8![Breeze Airways logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:56 am -
2 stops21h 42m
Deal found 8/7![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:56 am -
2 stops21h 56m
Deal found 8/8![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:56 am -
2 stops31h 25m
Deal found 8/10![Multiple Airlines logo]()
$129
Find flight deals from Louisville to South Carolina
Keep the following information in mind while searching for Louisville to South Carolina flight deals. Data was last updated August 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $97 (Kiwi.com) |
One-way from | $33 (Kiwi.com) |
Popular in | January |
Cheapest in | July |
Average price | $327 |
Good round-trip deal | $80 or less |
Good one-way deal | $71 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from Louisville to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleGreenville
SDF Louisville Intl - GSP Greenville
SDFGSP
Louisville Intl
Mon 8/31
11:50 am-4:05 pm
1 stop4h 15m
Greenville
Sat 9/5
6:45 am-12:05 pm
1 stop5h 20m
$246
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Fri 9/18
7:55 pm-11:59 pm
1 stop4h 04m
Charleston
Mon 9/21
6:40 am-10:19 am
1 stop3h 39m
$257
LouisvilleMyrtle Beach
SDF Louisville Intl - MYR Myrtle Beach Intl
SDFMYR
Louisville Intl
Fri 9/25
7:55 pm-11:28 pm
1 stop3h 33m
Myrtle Beach Intl
Thu 10/1
10:54 am-5:10 pm
1 stop6h 16m
$264
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Fri 8/21
11:50 am-7:10 pm
2 stops7h 20m
Charleston
Fri 8/28
7:00 am-3:30 pm
2 stops8h 30m
$267
LouisvilleHilton Head Island
SDF Louisville Intl - HHH Hilton Head Island
SDFHHH
Louisville Intl
Sat 10/24
6:00 am-10:25 am
1 stop4h 25m
Hilton Head Island
Sat 10/31
10:55 am-5:46 pm
1 stop6h 51m
$271
LouisvilleSavannah
SDF Louisville Intl - SAV Savannah/Hilton Head
SDFSAV
Louisville Intl
Mon 8/31
6:15 am-2:16 pm
1 stop8h 01m
Savannah/Hilton Head
Fri 9/4
12:59 pm-7:15 pm
1 stop6h 16m
$276
LouisvilleGreenville
SDF Louisville Intl - GSP Greenville
SDFGSP
Louisville Intl
Fri 9/4
3:20 pm-9:35 pm
1 stop6h 15m
Greenville
Sat 9/5
6:45 am-12:05 pm
1 stop5h 20m
$280
LouisvilleSavannah
SDF Louisville Intl - SAV Savannah/Hilton Head
SDFSAV
Louisville Intl
Fri 9/11
6:45 am-3:35 pm
2 stops8h 50m
Savannah/Hilton Head
Fri 9/11
5:35 pm-10:40 pm
1 stop5h 05m
$284
LouisvilleMyrtle Beach
SDF Louisville Intl - MYR Myrtle Beach Intl
SDFMYR
Louisville Intl
Wed 9/9
6:00 am-10:07 am
1 stop4h 07m
Myrtle Beach Intl
Fri 9/11
6:00 am-10:19 am
1 stop4h 19m
$289
LouisvilleHilton Head Island
SDF Louisville Intl - HHH Hilton Head Island
SDFHHH
Louisville Intl
Tue 9/1
11:17 am-3:32 pm
1 stop4h 15m
Hilton Head Island
Wed 9/9
12:17 pm-9:16 pm
2 stops8h 59m
$290
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Louisville to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Louisville with our price prediction graph.
SDF-SAV
SDF-CHS
SDF-CLT
SDF-MYR
SDF-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to South Carolina
SDF-USSC
SDF-SAV
SDF-CHS
SDF-CLT
SDF-MYR
What is the cheapest month to book a flight from Louisville to South Carolina?
Currently, July is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $230). Flying from Louisville to South Carolina in April is currently the most expensive (average of $406). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SDF to SC?
Find hourly flight availability from Louisville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 11, 2026.
A simple way to save on the total cost of your ticket is to fly from Louisville to South Carolina in the morning. If you’re flexible enough to do this you can expect to save up to 70% on your trip compared to booking a flight at noon.
How much does it cost to fly round-trip from Louisville to South Carolina?
Airfare is below average for this route at the moment.
Louisville to South Carolina flights typically cost between $236 and $394 in September.The cheapest round-trip price found within the last 5 days was $97 on Breeze Airways (Sep 18-Sep 21).
How far ahead should I book a flight from Louisville to South Carolina?
To ensure you get the cheapest price possible for a flight from Louisville to South Carolina, you should look to book at least 31 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 11, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Louisville to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.2
Entertainment
6.7
Crew
8.7
Food
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.7
Crew
8.7
Food
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.7
Crew
8.7
Food
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.7
Crew
8.7
Food
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.7
Crew
8.7
Food
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.7
Crew
8.7
Food
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Louisville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Louisville to South Carolina
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Complete your trip
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Search flights from Louisville to South Carolina by cabin class
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Louisville and South Carolina flights
Browse other Louisville and South Carolina flight options. Last updated on August 11, 2026.
Popular flight searches
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Louisville to South Carolina flights
Consider these flights traveling from Louisville to South Carolina.
Top 6 airlines flying from Louisville to South Carolina
Discover the top 6 airlines that operate flights from Louisville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$63 | Average$135 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$88 | Average$152 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$134 | Average$383 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$196 | Average$364 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$388 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$274 | Average$443 | FlexibilityNo cancel fee | On-time69% |