$64+ Cheap flights from Louisville (SDF) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CHS
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to South Carolina
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Cheapest flights from Louisville to South CarolinaExplore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:59 pm -
Nonstop1h 35m
Mon 12/146:10 am -
Nonstop1h 52m
Deal found 11/1![Breeze Airways logo]()
$115
This Breeze Airways deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:59 pm -
Nonstop1h 35m
Mon 11/166:10 am -
Nonstop1h 52m
Deal found 10/30![Breeze Airways logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:16 pm -
1 stop20h 15m
Mon 12/146:10 am -
Nonstop1h 52m
Deal found 11/4![Multiple Airlines logo]()
$175
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop4h 07m
Sat 12/510:52 am -
1 stop3h 24m
Deal found 10/30![Delta logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:09 pm -
1 stop14h 35m
Thu 12/38:10 pm -
2 stops44h 22m
Deal found 10/30![Multiple Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:44 am -
1 stop6h 09m
Mon 12/74:24 pm -
1 stop5h 47m
Deal found 11/1![American Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:53 pm -
1 stop15h 02m
Thu 12/38:10 pm -
2 stops44h 22m
Deal found 10/30![Multiple Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:55 am -
2 stops7h 39m
Thu 12/176:10 pm -
1 stop5h 34m
Deal found 11/3![United Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:09 pm -
1 stop14h 35m
Fri 12/410:02 pm -
2 stops18h 30m
Deal found 10/30![Breeze Airways logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:53 pm -
1 stop15h 02m
Tue 12/14:08 pm -
2 stops24h 24m
Deal found 10/30![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:53 pm -
1 stop15h 02m
Sat 12/55:58 pm -
1 stop26h 31m
Deal found 10/30![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:09 pm -
1 stop14h 35m
Sat 12/510:08 am -
2 stops10h 39m
Deal found 10/30![Breeze Airways logo]()
$351
Best flights from Louisville to South CarolinaDiscover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:59 pm -
Nonstop1h 35m
Mon 11/166:10 am -
Nonstop1h 52m
Deal found 10/30![Breeze Airways logo]()
$125
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:05 am -
1 stop4h 47m
Mon 11/308:00 am -
1 stop6h 15m
Deal found 11/2![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:55 am -
2 stops7h 39m
Thu 12/176:10 pm -
1 stop5h 34m
Deal found 11/3![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/159:45 am -
1 stop5h 52m
Sun 1/174:03 pm -
1 stop5h 12m
Deal found 10/31![American Airlines logo]()
$351
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:50 am -
2 stops10h 35m
Thu 12/178:55 pm -
2 stops13h 05m
Deal found 11/3![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:13 am -
1 stop4h 58m
Mon 11/167:04 pm -
1 stop5h 06m
Deal found 10/30![Delta logo]()
$237
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:05 am -
1 stop5h 28m
Thu 12/172:18 pm -
1 stop6h 36m
Deal found 11/3![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/136:15 am -
2 stops8h 09m
Tue 1/262:59 pm -
2 stops8h 41m
Deal found 10/30![United Airlines logo]()
$331
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:03 am -
1 stop5h 22m
Fri 1/16:30 am -
1 stop4h 31m
Deal found 10/31![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:30 am -
1 stop4h 06m
Mon 11/235:47 pm -
1 stop6h 33m
Deal found 11/3![American Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/282:10 pm -
2 stops7h 50m
Mon 1/46:35 am -
1 stop5h 35m
Deal found 11/3![Southwest logo]()
$402
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Sat 11/1410:55 am -
2 stops8h 13m
Wed 11/182:52 pm -
1 stop4h 38m
Deal found 10/30![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1310:26 am -
1 stop3h 23m
Tue 1/2610:49 am -
1 stop4h 23m
Deal found 10/30![Delta logo]()
$321
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:02 am -
1 stop5h 34m
Wed 11/255:47 pm -
1 stop6h 33m
Deal found 10/31![American Airlines logo]()
$410
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/29:50 am -
2 stops7h 58m
Wed 2/36:29 pm -
1 stop5h 11m
Deal found 10/31![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:50 am -
2 stops11h 05m
Sat 11/211:55 pm -
2 stops8h 50m
Deal found 10/31![Southwest logo]()
$429
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/119:50 am -
2 stops7h 58m
Fri 1/1511:27 am -
1 stop7h 47m
Deal found 11/3![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:22 am -
2 stops9h 31m
Mon 12/74:24 pm -
1 stop5h 47m
Deal found 11/1![American Airlines logo]()
$415
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:15 pm -
1 stop5h 00m
Sun 11/296:25 pm -
1 stop6h 35m
Deal found 11/2![Southwest logo]()
$438
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:55 am -
2 stops7h 39m
Sat 12/56:32 pm -
1 stop5h 27m
Deal found 11/1![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/176:00 am -
1 stop4h 08m
Sun 3/216:45 pm -
1 stop5h 17m
Deal found 11/1![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:10 pm -
2 stops7h 50m
Mon 12/284:55 pm -
2 stops6h 15m
Deal found 11/1![Southwest logo]()
$447
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop4h 07m
Thu 11/264:00 pm -
1 stop6h 38m
Deal found 11/1![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:00 am -
1 stop4h 50m
Sun 12/62:29 pm -
1 stop6h 31m
Deal found 11/1![United Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/182:35 pm -
2 stops7h 55m
Mon 3/226:30 am -
2 stops8h 35m
Deal found 11/3![Southwest logo]()
$457
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:00 am -
1 stop5h 00m
Fri 12/115:00 pm -
1 stop6h 49m
Deal found 10/30![United Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:05 am -
1 stop5h 09m
Sat 11/146:00 am -
1 stop4h 32m
Deal found 10/31![Delta logo]()
$411
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/156:19 am -
2 stops8h 43m
Sat 3/2011:04 am -
2 stops10h 23m
Deal found 11/3![American Airlines logo]()
$563
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop5h 08m
Sat 11/216:04 pm -
1 stop3h 38m
Deal found 11/4![Delta logo]()
$411
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:40 am -
1 stop5h 05m
Sat 11/214:55 pm -
1 stop5h 50m
Deal found 11/2![Southwest logo]()
$501
Last-minute flights from Louisville to South CarolinaDiscover last-minute flight deals from Louisville to South Carolina. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to South Carolina. Data last updated November 4, 2026 and is based on user searches.
This Breeze Airways deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:59 pm -
Nonstop1h 35m
Mon 11/166:10 am -
Nonstop1h 52m
Deal found 10/30![Breeze Airways logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:53 pm -
1 stop15h 02m
Thu 12/38:10 pm -
2 stops44h 22m
Deal found 10/30![Multiple Airlines logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:53 pm -
1 stop15h 02m
Tue 12/14:08 pm -
2 stops24h 24m
Deal found 10/30![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:53 pm -
1 stop15h 02m
Sat 12/55:58 pm -
1 stop26h 31m
Deal found 10/30![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:09 pm -
1 stop14h 35m
Thu 12/38:10 pm -
2 stops44h 22m
Deal found 10/30![Multiple Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:09 pm -
1 stop14h 35m
Fri 12/410:02 pm -
2 stops18h 30m
Deal found 10/30![Breeze Airways logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:09 pm -
1 stop14h 35m
Sat 12/510:08 am -
2 stops10h 39m
Deal found 10/30![Breeze Airways logo]()
$351
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop4h 07m
Sat 12/510:52 am -
1 stop3h 24m
Deal found 10/30![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:44 am -
1 stop6h 09m
Mon 12/74:24 pm -
1 stop5h 47m
Deal found 11/1![American Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:59 pm -
Nonstop1h 35m
Mon 12/146:10 am -
Nonstop1h 52m
Deal found 11/1![Breeze Airways logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:16 pm -
1 stop20h 15m
Mon 12/146:10 am -
Nonstop1h 52m
Deal found 11/4![Multiple Airlines logo]()
$175
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:55 am -
2 stops7h 39m
Thu 12/176:10 pm -
1 stop5h 34m
Deal found 11/3![United Airlines logo]()
$330
One-way flights from Louisville to South CarolinaSearch for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Super.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:59 pm -
Nonstop1h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Breeze Airways logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:59 pm -
Nonstop1h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Breeze Airways logo]()
$78
This Super.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:59 pm -
Nonstop1h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Breeze Airways logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1710:08 am -
1 stop7h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Allegiant Air logo]()
$125
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:55 pm -
1 stop4h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Delta logo]()
$140
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:05 am -
1 stop5h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Delta logo]()
$149
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:12 pm -
1 stop4h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![American Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:06 pm -
2 stops16h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Breeze Airways logo]()
$159
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/158:50 am -
2 stops8h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Southwest logo]()
$163
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:15 pm -
1 stop4h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Southwest logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:06 pm -
2 stops27h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Breeze Airways logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:36 pm -
2 stops36h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Multiple Airlines logo]()
$195
Find flight deals from Louisville to South Carolina
Keep the following information in mind while searching for Louisville to South Carolina flight deals. Data was last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $115 (Kiwi.com) |
One-way from | $64 (Super.com) |
Popular in | January |
Cheapest in | July |
Average price | $348 |
Good round-trip deal | $131 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Louisville to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Fri 12/25
7:59 pm-9:34 pm
Nonstop1h 35m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$79
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Fri 11/13
10:25 am-4:43 pm
1 stop6h 18m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$101
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Fri 11/13
7:59 pm-9:34 pm
Nonstop1h 35m
Charleston
Mon 11/16
6:10 am-8:02 am
Nonstop1h 52m
$125
LouisvilleMyrtle Beach
SDF Louisville Intl - MYR Myrtle Beach Intl
SDFMYR
Louisville Intl
Fri 11/27
6:00 am-10:07 am
1 stop4h 07m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
LouisvilleMyrtle Beach
SDF Louisville Intl - MYR Myrtle Beach Intl
SDFMYR
Louisville Intl
Thu 12/24
4:38 pm-9:22 pm
1 stop4h 44m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Tue 12/15
12:12 pm-4:57 pm
1 stop4h 45m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$158
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Wed 11/11
4:06 pm-8:38 am
2 stops16h 32m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$159
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Fri 12/4
10:25 am-10:33 pm
2 stops36h 08m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$161
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Tue 12/15
8:50 am-5:25 pm
2 stops8h 35m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
LouisvilleGreenville
SDF Louisville Intl - GSP Greenville
SDFGSP
Louisville Intl
Sun 12/20
7:15 pm-11:25 pm
1 stop4h 10m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$169
Showing 1-10 of 59 resultsSorted by cheapest first
Best time to book a flight from Louisville to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Louisville with our price prediction graph.
SDF-CHS
SDF-GSP
SDF-MYR
SDF-HHH
SDF-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to South Carolina
SDF-USSC
SDF-CHS
SDF-GSP
SDF-MYR
SDF-HHH
What is the cheapest month to book a flight from Louisville to South Carolina?
Currently, July is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $230). Flying from Louisville to South Carolina in April is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SDF to SC?
Find hourly flight availability from Louisville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2026.
A simple way to save on the total cost of your ticket is to fly from Louisville to South Carolina in the morning. If you’re flexible enough to do this you can expect to save up to 70% on your trip compared to booking a flight at noon.
How much does it cost to fly round-trip from Louisville to South Carolina?
Airfare is below average for this route at the moment.
Louisville to South Carolina flights typically cost between $130 and $323 in December.The cheapest round-trip price found within the last 5 days was $115 on Breeze Airways (Dec 7-Dec 14).
How far ahead should I book a flight from Louisville to South Carolina?
To ensure you get the cheapest price possible for a flight from Louisville to South Carolina, you should look to book at least 58 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 4, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Louisville to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.8
Food
6.7
Comfort
8.2
Overall
8.2
Entertainment
6.8
Boarding
8.4
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Crew
8.8
Food
6.7
Comfort
8.2
Overall
8.2
Entertainment
6.8
Boarding
8.4
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Crew
8.8
Food
6.7
Comfort
8.2
Overall
8.2
Entertainment
6.8
Boarding
8.4
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Crew
8.8
Food
6.7
Comfort
8.2
Overall
8.2
Entertainment
6.8
Boarding
8.4
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Crew
8.8
Food
6.7
Comfort
8.2
Overall
8.2
Entertainment
6.8
Boarding
8.4
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Crew
8.8
Food
6.7
Comfort
8.2
Overall
8.2
Entertainment
6.8
Boarding
8.4
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Related info for your journey
Find useful and relevant information for your journey from Louisville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Louisville to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to South Carolina by cabin class
Find flights from Louisville to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and South Carolina flights
Browse other Louisville and South Carolina flight options. Last updated on November 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisville to South Carolina flights
Consider these flights traveling from Louisville to South Carolina.
Top 6 airlines flying from Louisville to South Carolina
Discover the top 6 airlines that operate flights from Louisville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$63 | Average$134 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$88 | Average$154 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$226 | Average$408 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$234 | Average$351 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$234 | Average$396 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$386 | FlexibilityNo cancel fee | On-time63% |