$58+ Cheap flights from Louisville (SDF) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/31. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CHS
Aug 12 — Aug 191
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Louisville to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Louisville to South CarolinaExplore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
Explore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
This Booking.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/911:29 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 8/136:16 pm
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$62
This Booking.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:11 pm
SDF
- MYR
Nonstop1h 32m
Allegiant Air
Sat 8/1510:39 am
MYR
- SDF
Nonstop1h 42m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$63
This Booking.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:29 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 8/136:16 pm
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$70
This Booking.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/18:57 am
MYR
- SDF
Nonstop1h 34m
Allegiant Air
Deal found 7/11![Allegiant Air logo]()
$82
This Booking.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:45 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 8/166:16 pm
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$84
This Mytrip deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:07 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 8/69:00 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$86
This Super.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/181:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 7/2510:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/111:21 am
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/810:39 am
MYR
- SDF
Nonstop1h 42m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$91
This Trip.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3011:28 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 8/69:00 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$93
This Booking.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/911:29 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 8/166:16 pm
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Mon 8/317:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 7/9![Breeze Airways logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 8/217:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 7/10![Breeze Airways logo]()
$112
Best flights from Louisville to South CarolinaDiscover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
Discover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:25 am
SDF
- CHS
1 stop6h 18m
Breeze Airways
Fri 10/96:10 am
CHS
- SDF
Nonstop1h 52m
Breeze Airways
Deal found 7/12![Breeze Airways logo]()
$192
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 pm
SDF
- MYR
1 stop3h 42m
Delta
Tue 10/136:58 pm
MYR
- SDF
1 stop3h 37m
Delta
Deal found 7/10![Delta logo]()
$227
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:20 pm
SDF
- CHS
1 stop3h 50m
Southwest
Mon 8/316:05 pm
CHS
- SDF
1 stop4h 30m
Southwest
Deal found 7/10![Southwest logo]()
$235
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:10 am
SDF
- CHS
2 stops7h 40m
United Airlines
Sat 9/268:00 am
CHS
- SDF
1 stop5h 15m
United Airlines
Deal found 7/8![United Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:39 am
SDF
- GSP
1 stop7h 12m
Multiple Airlines
Sun 8/308:37 am
GSP
- SDF
1 stop25h 52m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$293
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:05 am
SDF
- SAV
1 stop3h 54m
American Airlines
Sun 8/167:05 am
SAV
- SDF
1 stop4h 10m
American Airlines
Deal found 7/12![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:25 pm
SDF
- GSP
1 stop3h 44m
Delta
Sat 8/225:20 pm
GSP
- SDF
1 stop4h 45m
Delta
Deal found 7/9![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:00 am
SDF
- SAV
1 stop6h 04m
United Airlines
Tue 8/253:23 pm
SAV
- SDF
1 stop7h 36m
United Airlines
Deal found 7/10![United Airlines logo]()
$246
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:05 am
SDF
- GSP
1 stop5h 20m
Southwest
Wed 8/55:30 pm
GSP
- SDF
1 stop3h 05m
Southwest
Deal found 7/8![Southwest logo]()
$252
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:52 am
SDF
- GSP
1 stop4h 03m
Delta
Tue 8/258:49 am
GSP
- SDF
1 stop3h 32m
Delta
Deal found 7/9![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:20 pm
SDF
- MYR
1 stop4h 00m
Southwest
Mon 9/146:15 pm
MYR
- SDF
1 stop4h 20m
Southwest
Deal found 7/9![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:55 pm
SDF
- CHS
1 stop4h 02m
Delta
Mon 9/286:51 pm
CHS
- SDF
1 stop5h 08m
Delta
Deal found 7/12![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:05 am
SDF
- CAE
1 stop4h 16m
United Airlines
Tue 8/1810:22 am
CAE
- SDF
2 stops10h 14m
United Airlines
Deal found 7/9![United Airlines logo]()
$276
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1411:50 am
SDF
- GSP
1 stop4h 15m
Southwest
Mon 8/177:00 am
GSP
- SDF
1 stop6h 05m
Southwest
Deal found 7/10![Southwest logo]()
$258
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:42 am
SDF
- HHH
1 stop4h 03m
American Airlines
Tue 9/225:15 pm
HHH
- SDF
1 stop6h 07m
American Airlines
Deal found 7/12![American Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:09 am
SDF
- CHS
1 stop3h 29m
Delta
Tue 10/68:00 am
CHS
- SDF
1 stop5h 49m
Delta
Deal found 7/8![Delta logo]()
$251
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:05 am
SDF
- CLT
1 stop5h 40m
Southwest
Thu 8/207:40 am
CLT
- SDF
1 stop7h 50m
Southwest
Deal found 7/8![Southwest logo]()
$263
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am
SDF
- MYR
1 stop3h 44m
United Airlines
Wed 10/710:23 am
MYR
- SDF
2 stops9h 50m
United Airlines
Deal found 7/8![United Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:55 pm
SDF
- MYR
1 stop3h 34m
Delta
Tue 10/66:58 pm
MYR
- SDF
1 stop3h 37m
Delta
Deal found 7/8![Delta logo]()
$257
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:28 am
SDF
- HHH
1 stop5h 47m
American Airlines
Sat 8/225:16 pm
HHH
- SDF
1 stop5h 55m
American Airlines
Deal found 7/8![American Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:10 am
SDF
- SAV
2 stops7h 28m
United Airlines
Sun 8/234:59 pm
SAV
- SDF
1 stop7h 00m
United Airlines
Deal found 7/8![United Airlines logo]()
$292
This Southwest deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:35 pm
SDF
- MYR
1 stop3h 55m
Southwest
Sat 10/171:10 pm
MYR
- SDF
1 stop6h 45m
Southwest
Deal found 7/12![Southwest logo]()
$281
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am
SDF
- HHH
1 stop4h 37m
American Airlines
Fri 10/212:50 pm
HHH
- SDF
1 stop4h 24m
American Airlines
Deal found 7/12![American Airlines logo]()
$350
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
SDF
- CAE
1 stop3h 17m
Delta
Tue 8/183:50 pm
CAE
- SDF
1 stop3h 43m
Delta
Deal found 7/9![Delta logo]()
$271
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
SDF
- CHS
1 stop4h 11m
United Airlines
Thu 8/1310:14 am
CHS
- SDF
2 stops9h 59m
United Airlines
Deal found 7/10![United Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:50 am
SDF
- GSP
1 stop3h 55m
Southwest
Sat 10/2411:20 am
GSP
- SDF
1 stop3h 35m
Southwest
Deal found 7/9![Southwest logo]()
$288
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:17 am
SDF
- MYR
1 stop3h 53m
Delta
Sat 9/56:00 am
MYR
- SDF
1 stop4h 32m
Delta
Deal found 7/11![Delta logo]()
$273
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/234:55 pm
SDF
- AGS
1 stop4h 49m
American Airlines
Sun 8/302:55 pm
AGS
- SDF
1 stop4h 30m
American Airlines
Deal found 7/9![American Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/812:05 pm
SDF
- GSP
1 stop2h 50m
Southwest
Mon 8/101:05 pm
GSP
- SDF
2 stops9h 30m
Southwest
Deal found 7/9![Southwest logo]()
$293
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:55 pm
SDF
- CHS
1 stop4h 02m
Delta
Thu 10/85:30 am
CHS
- SDF
1 stop3h 20m
Delta
Deal found 7/8![Delta logo]()
$281
Last-minute flights from Louisville to South CarolinaDiscover last-minute flight deals from Louisville to South Carolina. Data last updated July 13, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to South Carolina. Data last updated July 13, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/181:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 7/2510:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$89
This Booking.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/18:57 am
MYR
- SDF
Nonstop1h 34m
Allegiant Air
Deal found 7/11![Allegiant Air logo]()
$82
This Trip.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3011:28 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 8/69:00 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/111:21 am
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/810:39 am
MYR
- SDF
Nonstop1h 42m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$91
This Mytrip deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:07 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 8/69:00 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$86
This Booking.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:29 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 8/136:16 pm
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$70
This Booking.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:11 pm
SDF
- MYR
Nonstop1h 32m
Allegiant Air
Sat 8/1510:39 am
MYR
- SDF
Nonstop1h 42m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$63
This Booking.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/911:29 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Thu 8/136:16 pm
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$62
This Booking.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/911:29 am
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 8/166:16 pm
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$97
This Booking.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:45 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 8/166:16 pm
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 8/217:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 7/10![Breeze Airways logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Mon 8/317:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 7/9![Breeze Airways logo]()
$102
One-way flights from Louisville to South CarolinaSearch for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
Search for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 7/9![Breeze Airways logo]()
$58
This Super.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/194:52 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$60
This Super.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 7/10![Breeze Airways logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:59 pm
SDF
- CHS
Nonstop1h 35m
Breeze Airways
Deal found 7/10![Breeze Airways logo]()
$74
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:50 am
SDF
- GSP
1 stop4h 15m
Southwest
Deal found 7/8![Southwest logo]()
$114
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:05 am
SDF
- CHS
1 stop5h 05m
United Airlines
Deal found 7/10![United Airlines logo]()
$117
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:05 pm
SDF
- CHS
1 stop3h 35m
Southwest
Deal found 7/9![Southwest logo]()
$119
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:45 am
SDF
- CHS
2 stops8h 40m
Southwest
Deal found 7/10![Southwest logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/189:00 pm
SDF
- GSP
1 stop10h 35m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$126
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:05 am
SDF
- CLT
1 stop5h 40m
Southwest
Deal found 7/10![Southwest logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 7/9![Breeze Airways logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:55 pm
SDF
- MYR
1 stop20h 11m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$134
Find flight deals from Louisville to South Carolina
Keep the following information in mind while searching for Louisville to South Carolina flight deals. Data was last updated July 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $62 (Booking.com) |
One-way from | $58 (Kiwi.com) |
Popular in | January |
Cheapest in | June |
Average price | $320 |
Good round-trip deal | $80 or less |
Good one-way deal | $74 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
Use the filters below to find and compare flights from Louisville to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Mon 10/5
10:25 am-4:43 pm
1 stop6h 18m
Charleston
Fri 10/9
6:10 am-8:02 am
Nonstop1h 52m
$192
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Sat 10/3
6:00 pm-9:42 pm
1 stop3h 42m
Myrtle Beach Intl
Tue 10/13
6:58 pm-10:35 pm
1 stop3h 37m
$227
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Fri 8/28
3:20 pm-7:10 pm
1 stop3h 50m
Charleston
Mon 8/31
6:05 pm-10:35 pm
1 stop4h 30m
$235
LouisvilleGreenville
SDF - GSP
SDFGSP
Louisville Intl
Mon 8/17
3:25 pm-7:09 pm
1 stop3h 44m
Greenville
Sat 8/22
5:20 pm-10:05 pm
1 stop4h 45m
$237
LouisvilleGreenville
SDF - GSP
SDFGSP
Louisville Intl
Mon 8/17
9:52 am-1:55 pm
1 stop4h 03m
Greenville
Tue 8/25
8:49 am-12:21 pm
1 stop3h 32m
$237
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Fri 9/25
7:55 pm-11:57 pm
1 stop4h 02m
Charleston
Mon 9/28
6:51 pm-11:59 pm
1 stop5h 08m
$237
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Sat 9/19
7:10 am-2:50 pm
2 stops7h 40m
Charleston
Sat 9/26
8:00 am-1:15 pm
1 stop5h 15m
$238
LouisvilleSavannah
SDF - SAV
SDFSAV
Louisville Intl
Fri 8/21
9:00 am-3:04 pm
1 stop6h 04m
Savannah/Hilton Head
Tue 8/25
3:23 pm-10:59 pm
1 stop7h 36m
$246
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Mon 10/5
8:09 am-11:38 am
1 stop3h 29m
Charleston
Tue 10/6
8:00 am-1:49 pm
1 stop5h 49m
$251
LouisvilleGreenville
SDF - GSP
SDFGSP
Louisville Intl
Tue 8/4
7:05 am-12:25 pm
1 stop5h 20m
Greenville
Wed 8/5
5:30 pm-8:35 pm
1 stop3h 05m
$252
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Louisville to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Louisville with our price prediction graph.
SDF-CHS
SDF-GSP
SDF-MYR
SDF-SAV
SDF-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to South Carolina
SDF-USSC
SDF-CHS
SDF-GSP
SDF-MYR
SDF-SAV
What is the cheapest month to book a flight from Louisville to South Carolina?
Currently, June is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $38). Flying from Louisville to South Carolina in April is currently the most expensive (average of $274). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SDF to SC?
Find hourly flight availability from Louisville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 13, 2026.
A simple way to save on the total cost of your ticket is to fly from Louisville to South Carolina in the afternoon. If you’re flexible enough to do this you can expect to save up to 63% on your trip compared to booking a flight at noon.
How much does it cost to fly round-trip from Louisville to South Carolina?
How far ahead should I book a flight from Louisville to South Carolina?
To ensure you get the cheapest price possible for a flight from Louisville to South Carolina, you should look to book at least 31 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 13, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Louisville to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.7
Comfort
8.2
Crew
8.8
Overall
8.2
Food
6.7
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Comfort
8.2
Crew
8.8
Overall
8.2
Food
6.7
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Comfort
8.2
Crew
8.8
Overall
8.2
Food
6.7
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Comfort
8.2
Crew
8.8
Overall
8.2
Food
6.7
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Comfort
8.2
Crew
8.8
Overall
8.2
Food
6.7
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Comfort
8.2
Crew
8.8
Overall
8.2
Food
6.7
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Louisville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Louisville to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to South Carolina by cabin class
Find flights from Louisville to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and South Carolina flights
Browse other Louisville and South Carolina flight options. Last updated on July 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisville to South Carolina flights
Consider these flights traveling from Louisville to South Carolina.
Top 6 airlines flying from Louisville to South Carolina
Discover the top 6 airlines that operate flights from Louisville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$69 | Average$144 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$88 | Average$140 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$118 | Average$359 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$148 | Average$359 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$196 | Average$361 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$386 | FlexibilityNo cancel fee | On-time63% |