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South Carolina

$44+ Cheap flights from Louisville (SDF) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CHS
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Louisville to South Carolina

Cheapest flights from Louisville to South Carolina
Explore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Breeze Airways deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Mon 12/87:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 10/28$88
This Breeze Airways deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/178:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Fri 11/217:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 10/28$103
This Breeze Airways deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Mon 11/177:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 10/29$110
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Mon 11/107:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 10/27$121
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Fri 11/217:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 10/27$125
This Priceline deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1211:55 amSDF - CHS
1 stop8h 59mMultiple Airlines
Mon 12/157:05 amCHS - SDF
Nonstop1h 53mMultiple Airlines
Deal found 10/29$132
This Breeze Airways deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/248:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Fri 11/287:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 10/28$134
This Priceline deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/511:55 amSDF - CHS
1 stop8h 59mMultiple Airlines
Mon 12/87:05 amCHS - SDF
Nonstop1h 53mMultiple Airlines
Deal found 10/27$137
This Breeze Airways deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Mon 11/247:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 10/27$139
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/178:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Mon 11/247:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 10/27$147
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/177:46 pmSDF - CLT
1 stop13h 16mMultiple Airlines
Thu 11/205:59 pmCLT - SDF
1 stop14h 49mMultiple Airlines
Deal found 10/27$214
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:55 amSDF - CLT
1 stop21h 44mSpirit Airlines
Sat 12/62:57 pmCLT - SDF
1 stop20h 03mSpirit Airlines
Deal found 10/28$228

Cheap flight deals from Louisville to South Carolina

Keep the following information in mind while searching for Louisville to South Carolina flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$88
(Breeze Airways)

One-way from

$44
(Breeze Airways)

Popular in

December

Cheapest in

March

Average price

$430

Good round-trip deal

$110 or less

Good one-way deal

$142 or less
Provider with most accurate pricing for Louisville Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Myrtle Beach Intl flights.
Search Deals
From Louisville Intl to South Carolina
Search Deals
One-way flight from Louisville Intl to South Carolina
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($81 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Louisville Intl to South Carolina.
Search Deals
Price to beat on a one-way flight from Louisville Intl to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Louisville to South Carolina that are best for you.

Fly from

Louisville

Fly to

South Carolina

Route

Depart

Return

Price

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Fri 12/5

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Mon 12/8

7:05 am-8:58 am

Nonstop1h 53m

$88

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Fri 12/12

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Mon 12/15

7:05 am-8:58 am

Nonstop1h 53m

$88

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Fri 11/14

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Mon 11/17

7:05 am-8:58 am

Nonstop1h 53m

$110

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Fri 11/21

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

Mon 11/24

7:05 am-8:58 am

Nonstop1h 53m

$139

LouisvilleCharlotte

SDF - CLT

SDFCLT

Louisville Intl

Mon 11/17

7:46 pm-9:02 am

1 stop13h 16m

Charlotte Douglas

Thu 11/20

5:59 pm-8:48 am

1 stop14h 49m

$214

LouisvilleHilton Head Island

SDF - HHH

SDFHHH

Louisville Intl

Wed 1/7

11:14 am-2:59 pm

1 stop3h 45m

Hilton Head Island

Thu 1/15

12:51 pm-6:30 pm

1 stop5h 39m

$229

LouisvilleColumbia

SDF - CAE

SDFCAE

Louisville Intl

Sat 3/7

5:45 pm-11:54 pm

1 stop6h 09m

Columbia Metropolitan

Tue 3/10

6:50 pm-11:56 pm

1 stop5h 06m

$229

LouisvilleHilton Head Island

SDF - HHH

SDFHHH

Louisville Intl

Thu 12/4

8:30 am-1:47 pm

1 stop5h 17m

Hilton Head Island

Mon 12/8

12:52 pm-6:12 pm

1 stop5h 20m

$229

LouisvilleHilton Head Island

SDF - HHH

SDFHHH

Louisville Intl

Tue 11/11

6:15 am-12:29 pm

1 stop6h 14m

Hilton Head Island

Sat 11/15

6:48 pm-12:22 am

1 stop5h 34m

$239

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Thu 11/27

6:00 am-9:26 am

1 stop3h 26m

Myrtle Beach Intl

Thu 11/27

4:45 pm-11:00 pm

1 stop6h 15m

$243

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results
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Best time to book a flight from Louisville to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to South Carolina

What is the cheapest month to book a flight from Louisville to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $41). Flying from Louisville to South Carolina in November is currently the most expensive (average of $86). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to SC?

Find hourly flight availability from Louisville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

A simple way to save on the total cost of your ticket is to fly from Louisville to South Carolina in the afternoon. If you’re flexible enough to do this you can expect to save up to 23% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Louisville to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Louisville to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Louisville to South Carolina flight should consider departing on Saturday at noon when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 29, 2025.
Get a feel of what it's like to fly with Breeze Airways, Delta, and American Airlines from Louisville to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
221 reviews

Boarding

8.3

Crew

8.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Food

6.7

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!
Breeze Airways
8.1
Very good
221 reviews
Breeze Airways
8.1
Very good
221 reviews

Boarding

8.3

Crew

8.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Food

6.7

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!
Delta
7.9
Good
7,992 reviews
Breeze Airways
8.1
Very good
221 reviews

Boarding

8.3

Crew

8.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Food

6.7

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!
American Airlines
7.2
Good
11,030 reviews
Breeze Airways
8.1
Very good
221 reviews

Boarding

8.3

Crew

8.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Food

6.7

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!
Allegiant Air
7.2
Good
695 reviews
Breeze Airways
8.1
Very good
221 reviews

Boarding

8.3

Crew

8.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Food

6.7

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!
Spirit Airlines
6.3
Okay
8,114 reviews
Breeze Airways
8.1
Very good
221 reviews

Boarding

8.3

Crew

8.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Food

6.7

Reviews

1 / 13
8.0
Excellent

Anonymous,Jul 2025

RIC - BDL

All went smoothly but the announcements from the crew were way to fast--approaching inaudible. Pilot announcements were perfect!

Related info for your journey

Find useful and relevant information for your journey from Louisville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to South Carolina?

    Most people fly from Louisville Intl (SDF) if they book a flight from Louisville to South Carolina. Louisville Intl is conveniently located just 5.3 mi from Louisville’s city center.

  • How popular is this Louisville to South Carolina flight route?

    The Louisville Intl to South Carolina flight path was viewed by 5 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Louisville to South Carolina?

    A quick flight from Louisville to South Carolina can take about 1h 36m. Breeze Airways provides one of the quickest options available for as low as $88. The distance from Louisville to South Carolina is about 485 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Louisville to South Carolina one-way?

    For one-way options, check prices for Breeze Airways. According to our data, you can fly for as low as $44. Users have also found prices from $80 and $146 on Spirit Airlines and American Airlines, respectively.

  • What are the most popular routes from Louisville to South Carolina?

    The most popular flight routes from Louisville to South Carolina are Louisville Intl - Charleston, Louisville Intl - Charlotte Douglas and Louisville Intl - Savannah/Hilton Head.

  • What are the cheapest flights from Louisville to South Carolina?

    Looking for the cheapest flight from Louisville to South Carolina? While on average our users pay $256, our data indicates the cheapest price to be $95. The most popular route (Louisville Intl - Charleston), is priced around $88.

  • Can I find deals for flights from Louisville to South Carolina that include hotel bookings?

    Yes. In addition to deals on Louisville to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to South Carolina.

  • Can I find deals for business class flights from Louisville to South Carolina?

    Yes. Cheapflights offers flight deals from Louisville to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $41). Flying from Louisville to South Carolina in November is currently the most expensive (average of $86). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Louisville to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Louisville to South Carolina

Discover the top 7 airlines that operate flights from Louisville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$77Average$140FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$86Average$177FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$88Average$133FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$148Average$430FlexibilityNo cancel feeOn-time69%
DeltaCheapest$149Average$327FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$190Average$341FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$219Average$348FlexibilityNo cancel feeOn-time63%

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