HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$87+ Cheap flights from Louisville (SDF) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CHS
dic. 29 — ene. 51
lun. 12/29
lun. 1/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Louisville to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Louisville to South Carolina

Cheapest flights from Louisville to South Carolina
Explore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/128:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
lun. 12/157:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 11/27$87
This Expedia deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1211:55 amSDF - CHS
1 stop8h 59mMultiple Airlines
lun. 12/157:05 amCHS - SDF
Nonstop1h 53mMultiple Airlines
Deal found 11/27$134
This Kiwi.com deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/158:52 pmSDF - CHS
Nonstop1h 36mMultiple Airlines
jue. 12/1810:18 pmCHS - SDF
1 stop25h 41mMultiple Airlines
Deal found 11/27$145
This Kiwi.com deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/198:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
lun. 12/227:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 11/28$149
This Kiwi.com deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/198:52 pmSDF - CHS
Nonstop1h 36mMultiple Airlines
lun. 12/2210:18 pmCHS - SDF
1 stop24h 31mMultiple Airlines
Deal found 11/28$151
This Breeze Airways deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/58:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
lun. 12/87:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 11/28$167
This Breeze Airways deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/228:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
vie. 12/267:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Deal found 11/29$179
This Kiwi.com deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/158:52 pmSDF - CHS
Nonstop1h 36mMultiple Airlines
mar. 12/307:05 amCHS - SDF
2 stops40h 54mMultiple Airlines
Deal found 11/28$210
This Kiwi.com deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/142:55 pmSDF - CLT
2 stops18h 42mMultiple Airlines
jue. 12/189:38 pmCLT - SDF
1 stop26h 21mMultiple Airlines
Deal found 11/27$260
This Kiwi.com deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/225:05 amSDF - CLT
1 stop9h 07mMultiple Airlines
dom. 12/289:34 pmCLT - SDF
2 stops26h 25mMultiple Airlines
Deal found 11/28$274
This Mytrip deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/205:05 amSDF - SAV
1 stop13h 22mMultiple Airlines
mar. 12/233:22 pmSAV - SDF
1 stop7h 27mMultiple Airlines
Deal found 11/28$280
This Kiwi.com deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/225:05 amSDF - CLT
1 stop9h 07mMultiple Airlines
sáb. 12/279:34 pmCLT - SDF
2 stops50h 25mMultiple Airlines
Deal found 11/27$281

Cheap flight deals from Louisville to South Carolina

Keep the following information in mind while searching for Louisville to South Carolina flight deals. Data was last updated noviembre 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$87
(Kiwi.com)

Popular in

December

Cheapest in

March

Average price

$318

Good round-trip deal

$110 or less

Good one-way deal

$51 or less
Provider with most accurate pricing for Louisville Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Myrtle Beach Intl flights.
Search Deals
From Louisville Intl to South Carolina
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($85 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Louisville Intl to South Carolina.
Search Deals
Price to beat on a one-way flight from Louisville Intl to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 29, 2025.
Use the filters below to find and compare flights from Louisville to South Carolina that are best for you.

Fly from

Louisville

Fly to

South Carolina

Route

Depart

Return

Price

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

vie. 12/12

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

lun. 12/15

7:05 am-8:58 am

Nonstop1h 53m

$87

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

vie. 12/19

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

lun. 12/22

7:05 am-8:58 am

Nonstop1h 53m

$149

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

vie. 12/19

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

lun. 12/22

10:18 pm-10:49 pm

1 stop24h 31m

$151

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

vie. 1/2

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

lun. 1/5

7:05 am-8:58 am

Nonstop1h 53m

$158

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

lun. 12/22

8:52 pm-10:28 pm

Nonstop1h 36m

Charleston

vie. 12/26

7:05 am-8:58 am

Nonstop1h 53m

$179

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

jue. 1/22

3:36 pm-5:36 pm

1 stop26h 00m

Charleston

lun. 1/26

6:35 pm-2:41 pm

1 stop20h 06m

$185

LouisvilleCharlotte

SDF - CLT

SDFCLT

Louisville Intl

jue. 1/22

3:36 pm-8:58 pm

1 stop29h 22m

Charlotte Douglas

jue. 1/29

9:58 pm-1:00 pm

1 stop15h 02m

$189

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

vie. 12/12

11:21 am-11:00 am

2 stops23h 39m

Charleston

lun. 12/15

7:05 am-8:58 am

Nonstop1h 53m

$192

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

lun. 12/15

11:21 am-8:54 pm

1 stop9h 33m

Charleston

jue. 12/18

10:18 pm-11:59 pm

1 stop25h 41m

$197

LouisvilleCharlotte

SDF - CLT

SDFCLT

Louisville Intl

dom. 1/25

3:28 pm-12:40 am

1 stop9h 12m

Charlotte Douglas

jue. 1/29

7:00 am-2:33 pm

1 stop7h 33m

$207

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/28

Showing 1-10 of 54 results
1
2
3
...
6

Best time to book a flight from Louisville to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to South Carolina

What is the cheapest month to book a flight from Louisville to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $41). Flying from Louisville to South Carolina in November is currently the most expensive (average of $82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to SC?

Find hourly flight availability from Louisville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 29, 2025.

A simple way to save on the total cost of your ticket is to fly from Louisville to South Carolina in the afternoon. If you’re flexible enough to do this you can expect to save up to 23% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Louisville to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Louisville to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Louisville to South Carolina flight should consider departing on Saturday at noon when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated noviembre 29, 2025.
Get a feel of what it's like to fly with Breeze Airways, Delta, and American Airlines from Louisville to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
240 reviews

Boarding

8.3

Crew

8.7

Food

6.7

Overall

8.2

Entertainment

6.6

Comfort

8.2

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!
Breeze Airways
8.2
Very good
240 reviews
Breeze Airways
8.2
Very good
240 reviews

Boarding

8.3

Crew

8.7

Food

6.7

Overall

8.2

Entertainment

6.6

Comfort

8.2

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!
Delta
7.9
Good
8,011 reviews
Breeze Airways
8.2
Very good
240 reviews

Boarding

8.3

Crew

8.7

Food

6.7

Overall

8.2

Entertainment

6.6

Comfort

8.2

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!
American Airlines
7.2
Good
11,043 reviews
Breeze Airways
8.2
Very good
240 reviews

Boarding

8.3

Crew

8.7

Food

6.7

Overall

8.2

Entertainment

6.6

Comfort

8.2

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!
Allegiant Air
7.2
Good
701 reviews
Breeze Airways
8.2
Very good
240 reviews

Boarding

8.3

Crew

8.7

Food

6.7

Overall

8.2

Entertainment

6.6

Comfort

8.2

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!
Spirit Airlines
6.3
Okay
8,162 reviews
Breeze Airways
8.2
Very good
240 reviews

Boarding

8.3

Crew

8.7

Food

6.7

Overall

8.2

Entertainment

6.6

Comfort

8.2

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!

Related info for your journey

Find useful and relevant information for your journey from Louisville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to South Carolina?

    Most people fly from Louisville Intl (SDF) if they book a flight from Louisville to South Carolina. Louisville Intl is conveniently located just 5.3 mi from Louisville’s city center.

  • How popular is this Louisville to South Carolina flight route?

    The Louisville Intl to South Carolina flight path was viewed by 5 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Louisville to South Carolina?

    A quick flight from Louisville to South Carolina can take about 1h 36m. Breeze Airways provides one of the quickest options available for as low as $87. The distance from Louisville to South Carolina is about 485 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Louisville to South Carolina one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $159. Users have also found prices from $164 and $164 on American Airlines and Southwest, respectively.

  • What are the most popular routes from Louisville to South Carolina?

    The most popular flight routes from Louisville to South Carolina are Louisville Intl - Charlotte Douglas, Louisville Intl - Charleston and Louisville Intl - Savannah/Hilton Head.

  • What are the cheapest flights from Louisville to South Carolina?

    Looking for the cheapest flight from Louisville to South Carolina? While on average our users pay $94, our data indicates the cheapest price to be $51. The most popular route (Louisville Intl - Charlotte Douglas), is priced around $189.

  • Can I find deals for flights from Louisville to South Carolina that include hotel bookings?

    Yes. In addition to deals on Louisville to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to South Carolina.

  • Can I find deals for business class flights from Louisville to South Carolina?

    Yes. Cheapflights offers flight deals from Louisville to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $41). Flying from Louisville to South Carolina in November is currently the most expensive (average of $82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Louisville to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Cincinnati to Orlando flights
Cincinnati to John F Kennedy Intl flights
Cincinnati to Fort Lauderdale flights
Nashville to LaGuardia flights
Cincinnati to LaGuardia flights
Cincinnati to Las Vegas flights
Cincinnati to Newark flights
Nashville to John F Kennedy Intl flights
Nashville to Newark flights
Cincinnati to Denver flights
Cincinnati to Sky Harbor Intl flights
Cincinnati to Tampa flights
Cincinnati to Miami flights
Cincinnati to Hobby flights
Cincinnati to Los Angeles flights
Cincinnati to Dallas/Fort Worth flights
Nashville to Hobby flights
Cincinnati to Fort Myers flights
Nashville to Los Angeles flights
Louisville to Newark flights
Nashville to Denver flights
Nashville to Las Vegas flights
Nashville to Miami flights
Cincinnati to George Bush Intcntl flights
Louisville to LaGuardia flights
Nashville to Fort Lauderdale flights
Nashville to Sky Harbor Intl flights
Nashville to Seattle flights
Nashville to Orlando flights
Cincinnati to Orlando Sanford Intl flights
Louisville to Miami flights
Louisville to Las Vegas flights
Nashville to George Bush Intcntl flights
Cincinnati to Seattle flights
Nashville to O'Hare Intl flights
Louisville to John F Kennedy Intl flights
Nashville to Salt Lake City flights
Nashville to San Francisco flights
Nashville to Boston flights
Nashville to Dallas/Fort Worth flights
Knoxville to LaGuardia flights
Nashville to Dulles Intl flights
Louisville to Fort Myers flights
Louisville to Orlando flights
Knoxville to O'Hare Intl flights
Nashville to Reagan-National flights
Nashville to Ontario flights
Louisville to Denver flights
Knoxville to Dallas/Fort Worth flights
Cincinnati to Atlanta flights

Top 7 airlines flying from Louisville to South Carolina

Discover the top 7 airlines that operate flights from Louisville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$77Average$140FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$86Average$177FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$88Average$127FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$137Average$309FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$148Average$430FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$190Average$336FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$219Average$349FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2025 Cheapflights