South America

$136+ Cheap flights from Myrtle Beach (MYR) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — BOG
ago. 23 — ago. 301
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Cheap flight deals from Myrtle Beach to South America

Keep the following information in mind while searching for Myrtle Beach to South America flight deals. Data was last updated agosto 18, 2025.

Round-trip from

$336
(Kiwi.com)

One-way from

$136
(Priceline)
From Myrtle Beach Intl to South America
One-way flight from Myrtle Beach Intl to South America

Find flight deals from Myrtle Beach to South America

Cheapest flights from Myrtle Beach to South America
Explore the most affordable flight options available from Myrtle Beach to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/17:36 pmMYR - MDE
1 stop29h 52mSpirit Airlines
mar. 10/71:12 amMDE - MYR
1 stop17h 52mSpirit Airlines
Deal found 8/17$336
This Expedia deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/318:36 pmMYR - BOG
1 stop16h 24mSpirit Airlines
mié. 9/31:54 pmBOG - MYR
2 stops25h 31mSpirit Airlines
Deal found 8/17$359
This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/147:36 pmMYR - BOG
2 stops17h 24mSpirit Airlines
dom. 9/212:05 pmBOG - MYR
1 stop29h 01mSpirit Airlines
Deal found 8/17$376
This Mytrip deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/236:45 amMYR - MDE
1 stop7h 19mSpirit Airlines
vie. 8/2912:49 amMDE - MYR
2 stops17h 56mSpirit Airlines
Deal found 8/16$412
This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/262:40 pmMYR - BOG
1 stop23h 19mSpirit Airlines
vie. 8/2912:55 pmBOG - MYR
1 stop21h 06mSpirit Airlines
Deal found 8/17$427
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/127:36 pmMYR - CTG
1 stop17h 47mMultiple Airlines
mar. 9/162:45 pmCTG - MYR
2 stops28h 21mMultiple Airlines
Deal found 8/17$432
This Avianca Connect deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/236:31 pmMYR - MDE
1 stop23h 09mMultiple Airlines
sáb. 8/305:59 amMDE - MYR
1 stop12h 46mMultiple Airlines
Deal found 8/16$436
This Avianca Connect deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/317:26 pmMYR - BOG
1 stop23h 33mMultiple Airlines
mié. 9/39:00 amBOG - MYR
1 stop10h 09mMultiple Airlines
Deal found 8/17$450
This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/127:17 pmMYR - CTG
2 stops18h 06mSpirit Airlines
mar. 9/161:29 pmCTG - MYR
2 stops22h 00mSpirit Airlines
Deal found 8/17$464
This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/288:36 pmMYR - BOG
1 stop16h 24mSpirit Airlines
dom. 8/311:54 pmBOG - MYR
2 stops28h 51mSpirit Airlines
Deal found 8/16$482
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/127:36 pmMYR - CTG
1 stop17h 47mMultiple Airlines
lun. 9/155:27 amCTG - MYR
2 stops13h 39mMultiple Airlines
Deal found 8/17$497
This LATAM Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/246:55 pmMYR - LIM
1 stop11h 05mLATAM Airlines
mar. 10/712:05 amLIM - MYR
2 stops16h 58mLATAM Airlines
Deal found 8/16$595

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
Use the filters below to find and compare flights from Myrtle Beach to South America that are best for you.

Fly from

Myrtle Beach

Fly to

South America

Route

Depart

Return

Price

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

mié. 10/1

7:36 pm-12:28 am

1 stop29h 52m

Medellín Jose Maria Cordova Intl

mar. 10/7

1:12 am-8:04 pm

1 stop17h 52m

$336

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

dom. 8/31

8:36 pm-12:00 pm

1 stop16h 24m

Bogotá El Dorado

mié. 9/3

1:54 pm-4:25 pm

2 stops25h 31m

$359

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

dom. 9/14

7:36 pm-12:00 pm

2 stops17h 24m

Bogotá El Dorado

dom. 9/21

2:05 pm-8:06 pm

1 stop29h 01m

$376

Myrtle BeachCartagena

MYR - CTG

MYRCTG

Myrtle Beach Intl

vie. 9/12

7:36 pm-12:23 pm

1 stop17h 47m

Cartagena Rafael Nunez

mar. 9/16

2:45 pm-8:06 pm

2 stops28h 21m

$432

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

dom. 8/31

7:26 pm-5:59 pm

1 stop23h 33m

Bogotá El Dorado

mié. 9/3

9:00 am-8:09 pm

1 stop10h 09m

$450

Myrtle BeachCartagena

MYR - CTG

MYRCTG

Myrtle Beach Intl

vie. 9/12

7:17 pm-12:23 pm

2 stops18h 06m

Cartagena Rafael Nunez

mar. 9/16

1:29 pm-12:29 pm

2 stops22h 00m

$464

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

jue. 8/28

8:36 pm-12:00 pm

1 stop16h 24m

Bogotá El Dorado

dom. 8/31

1:54 pm-7:45 pm

2 stops28h 51m

$482

Myrtle BeachCartagena

MYR - CTG

MYRCTG

Myrtle Beach Intl

vie. 9/12

7:36 pm-12:23 pm

1 stop17h 47m

Cartagena Rafael Nunez

lun. 9/15

5:27 am-8:06 pm

2 stops13h 39m

$497

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

dom. 9/14

6:00 am-3:15 am

2 stops22h 15m

Bogotá El Dorado

sáb. 9/20

1:35 am-11:49 pm

2 stops21h 14m

$588

Myrtle BeachLima

MYR - LIM

MYRLIM

Myrtle Beach Intl

mar. 9/16

10:55 am-5:00 am

1 stop19h 05m

Lima J Chavez Intl

mar. 9/23

11:20 pm-6:07 pm

1 stop17h 47m

$595

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Showing 1-10 of 23 results
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Best time to book a flight from Myrtle Beach to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to South America

What is the cheapest month to book a flight from Myrtle Beach to South America?

Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to South America (average of $359). Flying from Myrtle Beach to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SA?

Find hourly flight availability from Myrtle Beach to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 18, 2025.

When flying from Myrtle Beach to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated agosto 18, 2025.
Peruse reviews from past customers who have flown with LATAM Airlines and Spirit Airlines from Myrtle Beach to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.4

Entertainment

7.0

Food

6.7

Crew

8.0

Overall

7.5

Boarding

7.6

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

Comfort

7.4

Entertainment

7.0

Food

6.7

Crew

8.0

Overall

7.5

Boarding

7.6

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

Comfort

7.4

Entertainment

7.0

Food

6.7

Crew

8.0

Overall

7.5

Boarding

7.6

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Myrtle Beach to South America?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly out of when you book flights from Myrtle Beach to South America.

  • How long is the flight from Myrtle Beach to South America?

    Spirit Airlines and LATAM Airlines can get you from Myrtle Beach to South America in just under 19h 05m. Your travel time can differ by up to 10h 47m. There are 3158 mi between Myrtle Beach and South America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Myrtle Beach to South America?

  • Can I find deals for flights from Myrtle Beach to South America that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to South America.

  • Can I find deals for business class flights from Myrtle Beach to South America?

    Yes. Cheapflights offers flight deals from Myrtle Beach to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to South America?

    Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to South America (average of $359). Flying from Myrtle Beach to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Myrtle Beach to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Myrtle Beach to South America

Discover the top 2 airlines that operate flights from Myrtle Beach to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$333Average$414FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$593Average$722FlexibilityNo cancel feeOn-time81%

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