South America

$333+ Cheap flights from McAllen (MFE) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — BOG
Jan 17 — Jan 241
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Cheap flight deals from McAllen to South America

Cheapest flights from McAllen to South America
Explore the most affordable flight options available from McAllen to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/279:33 amMFE - BOG
1 stop12h 57mAmerican Airlines
Wed 12/3111:55 pmBOG - MFE
1 stop11h 36mAmerican Airlines
Deal found 12/17$693
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:15 pmMFE - GRU
1 stop18h 15mUnited Airlines
Mon 12/2910:15 pmGRU - MFE
1 stop16h 23mUnited Airlines
Deal found 12/16$1,740
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:25 amMFE - GRU
2 stops25h 10mDelta
Mon 12/2911:45 pmGRU - MFE
2 stops19h 50mDelta
Deal found 12/16$1,745
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:15 pmMFE - GRU
1 stop18h 15mUnited Airlines
Sun 12/2810:15 pmGRU - MFE
1 stop18h 15mUnited Airlines
Deal found 12/16$1,780
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:25 amMFE - GRU
2 stops25h 10mDelta
Sat 12/279:00 pmGRU - MFE
2 stops22h 35mDelta
Deal found 12/16$1,785

Find flight deals from McAllen to South America

Keep the following information in mind while searching for McAllen to South America flight deals. Data was last updated December 18, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$483
(American Airlines)

One-way from

$333
(United Airlines)
Provider with most accurate pricing for McAllen Miller Intl-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for McAllen Miller Intl-Sao Paulo (SAO) flights.
From McAllen Miller Intl to South America
One-way flight from McAllen Miller Intl to South America

Cheapflights Fare Finder

 
Customize your flight search to find flights from McAllen to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from McAllen to South America that are best for you.

Fly from

McAllen

Fly to

South America

Route

Depart

Return

Price

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Fri 4/17

7:35 am-9:55 pm

1 stop14h 20m

Bogotá El Dorado

Wed 4/22

12:53 am-4:14 pm

1 stop15h 21m

$483

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Sat 4/18

7:00 am-7:20 pm

1 stop12h 20m

Bogotá El Dorado

Wed 4/22

8:30 am-7:59 pm

1 stop11h 29m

$483

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Fri 4/17

5:25 pm-1:50 pm

2 stops20h 25m

Bogotá El Dorado

Thu 4/23

8:40 am-11:59 pm

2 stops15h 19m

$488

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Sat 1/31

7:00 am-10:35 pm

1 stop14h 35m

Bogotá El Dorado

Sat 2/7

8:15 am-9:57 pm

1 stop14h 42m

$518

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Sat 1/31

6:04 am-10:10 pm

2 stops15h 06m

Bogotá El Dorado

Sat 2/7

3:15 pm-11:30 am

2 stops21h 15m

$523

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Sat 1/24

12:05 pm-5:10 am

1 stop16h 05m

Bogotá El Dorado

Tue 1/27

1:30 am-4:07 pm

1 stop15h 37m

$553

McAllenCartagena

MFE - CTG

MFECTG

McAllen Miller Intl

Sun 1/25

12:05 pm-11:00 pm

2 stops33h 55m

Cartagena Rafael Nunez

Thu 1/29

6:24 am-8:05 pm

2 stops14h 41m

$576

McAllenSanta Cruz de la Sierra

MFE - VVI

MFEVVI

McAllen Miller Intl

Fri 4/24

5:17 am-10:42 pm

2 stops40h 25m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/28

11:48 am-5:55 pm

2 stops31h 07m

$722

McAllenBuenos Aires

MFE - EZE

MFEEZE

McAllen Miller Intl

Wed 2/11

5:25 pm-9:20 am

1 stop12h 55m

Buenos Aires Ministro Pistarini

Sat 2/21

11:55 pm-11:29 am

1 stop14h 34m

$1,016

McAllenBuenos Aires

MFE - EZE

MFEEZE

McAllen Miller Intl

Wed 2/11

5:25 am-7:20 am

2 stops22h 55m

Buenos Aires Ministro Pistarini

Sat 2/21

8:55 pm-4:54 pm

2 stops22h 59m

$1,020

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 19 results
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Best time to book a flight from McAllen to South America

Have a flexible travel schedule? Discover the best time to fly to South America from McAllen with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from McAllen to South America

What is the cheapest month to book a flight from McAllen to South America?

Currently, April is the cheapest month in which you can book a flight from McAllen to South America (average of $433). Flying from McAllen to South America in December is currently the most expensive (average of $815). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFE to SA?

Find hourly flight availability from McAllen to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from McAllen to South America in the evening. By choosing this option you can save up to 37% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 18, 2025.
Get a feel of what it's like to fly with United Airlines and American Airlines from McAllen to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.1

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability

Entertainment

7.1

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability

Entertainment

7.1

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Reviews

1 / 20
4.0
Okay

Kevin,Dec 2025

BOS - EWR

Seems like every United flight has a delay and it’s always someone else’s fault. Step up and take some accountability

Related info for your journey

Find useful and relevant information for your journey from McAllen to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from McAllen to South America?

    Located just 2.0 mi from the city center, McAllen Miller Intl (MFE) is the airport most travelers will use when flying to South America from McAllen.

  • How long is the flight from McAllen to South America?

    Departing from McAllen to South America will take you 12h 20m. The distance from McAllen to South America is about 2175 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from McAllen to South America?

  • Can I find deals for flights from McAllen to South America that include hotel bookings?

    Yes. In addition to deals on McAllen to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from McAllen to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from McAllen to South America.

  • Can I find deals for business class flights from McAllen to South America?

    Yes. Cheapflights offers flight deals from McAllen to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from McAllen to South America?

    Currently, April is the cheapest month in which you can book a flight from McAllen to South America (average of $433). Flying from McAllen to South America in December is currently the most expensive (average of $815). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for McAllen to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from McAllen to South America

Discover the top 2 airlines that operate flights from McAllen to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$443Average$692FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$594Average$1,184FlexibilityNo cancel feeOn-time69%

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