South America

$558+ Cheap flights from McAllen (MFE) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — BOG
Nov 29 — Dec 61
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Cheap flight deals from McAllen to South America

Keep the following information in mind while searching for McAllen to South America flight deals. Data was last updated October 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$393
(Kiwi.com)
Provider with most accurate pricing for McAllen Miller Intl-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for McAllen Miller Intl-Sao Paulo (SAO) flights.
From McAllen Miller Intl to South America

Find flight deals from McAllen to South America

Cheapest flights from McAllen to South America
Explore the most affordable flight options available from McAllen to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:25 amMFE - BOG
2 stops13h 55mDelta
Mon 12/83:55 pmBOG - MFE
2 stops21h 14mDelta
Deal found 10/29$558
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:09 pmMFE - BOG
2 stops20h 06mAmerican Airlines
Mon 12/811:55 pmBOG - MFE
1 stop10h 02mAmerican Airlines
Deal found 10/29$653
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:00 amMFE - BOG
1 stop17h 35mUnited Airlines
Sun 11/21:30 amBOG - MFE
1 stop15h 27mUnited Airlines
Deal found 10/28$693
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:31 pmMFE - BOG
2 stops20h 44mAmerican Airlines
Mon 11/33:15 pmBOG - MFE
2 stops20h 27mAmerican Airlines
Deal found 10/28$698
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:14 pmMFE - BOG
2 stops24h 55mMultiple Airlines
Mon 12/83:05 pmBOG - MFE
3 stops25h 49mMultiple Airlines
Deal found 10/29$732
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:30 pmMFE - BOG
2 stops16h 50mMultiple Airlines
Thu 12/181:35 amBOG - MFE
1 stop13h 20mMultiple Airlines
Deal found 10/28$753
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:09 pmMFE - BOG
2 stops20h 06mAmerican Airlines
Fri 12/193:15 pmBOG - MFE
2 stops18h 42mAmerican Airlines
Deal found 10/28$788
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/292:59 pmMFE - CTG
2 stops21h 26mAmerican Airlines
Wed 11/54:30 pmCTG - MFE
2 stops24h 44mAmerican Airlines
Deal found 10/28$842
This United deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/19:50 amMFE - BOG
2 stops19h 10mMultiple Airlines
Sun 11/21:30 amBOG - MFE
1 stop15h 27mMultiple Airlines
Deal found 10/28$868
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:16 pmMFE - CTG
2 stops19h 14mAmerican Airlines
Mon 12/224:30 pmCTG - MFE
2 stops17h 27mAmerican Airlines
Deal found 10/30$996
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:48 pmMFE - CTG
3 stops23h 37mMultiple Airlines
Wed 11/52:20 pmCTG - MFE
3 stops31h 31mMultiple Airlines
Deal found 10/28$1,109
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/112:44 pmMFE - EZE
2 stops17h 16mDelta
Sat 1/108:55 pmEZE - MFE
2 stops22h 50mDelta
Deal found 10/29$1,555

Cheapflights Fare Finder

 
Customize your flight search to find flights from McAllen to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from McAllen to South America that are best for you.

Fly from

McAllen

Fly to

South America

Route

Depart

Return

Price

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Fri 12/5

5:25 am-8:20 pm

2 stops13h 55m

Bogotá El Dorado

Mon 12/8

3:55 pm-12:09 pm

2 stops21h 14m

$558

McAllenCartagena

MFE - CTG

MFECTG

McAllen Miller Intl

Mon 3/23

9:40 am-11:00 pm

2 stops13h 20m

Cartagena Rafael Nunez

Fri 3/27

9:42 am-11:24 pm

2 stops13h 42m

$559

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Thu 1/22

9:30 am-10:35 pm

1 stop12h 05m

Bogotá El Dorado

Tue 1/27

1:30 am-9:57 pm

1 stop21h 27m

$561

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Thu 1/22

12:04 pm-10:40 pm

3 stops33h 36m

Bogotá El Dorado

Wed 1/28

3:05 pm-11:14 am

2 stops21h 09m

$566

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Fri 12/5

5:09 pm-2:15 pm

2 stops20h 06m

Bogotá El Dorado

Mon 12/8

11:55 pm-8:57 am

1 stop10h 02m

$653

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Fri 12/5

12:14 pm-2:09 pm

2 stops24h 55m

Bogotá El Dorado

Mon 12/8

3:05 pm-3:54 pm

3 stops25h 49m

$732

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Fri 12/12

3:30 pm-9:20 am

2 stops16h 50m

Bogotá El Dorado

Thu 12/18

1:35 am-1:55 pm

1 stop13h 20m

$753

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Fri 12/12

5:09 pm-2:15 pm

2 stops20h 06m

Bogotá El Dorado

Fri 12/19

3:15 pm-8:57 am

2 stops18h 42m

$788

McAllenCartagena

MFE - CTG

MFECTG

McAllen Miller Intl

Thu 12/18

7:16 pm-3:30 pm

2 stops19h 14m

Cartagena Rafael Nunez

Mon 12/22

4:30 pm-8:57 am

2 stops17h 27m

$996

McAllenBuenos Aires

MFE - EZE

MFEEZE

McAllen Miller Intl

Wed 2/11

1:03 pm-8:25 am

1 stop16h 22m

Buenos Aires Ministro Pistarini

Sat 2/21

10:25 pm-10:31 am

1 stop15h 06m

$1,016

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 16 results
1
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Best time to book a flight from McAllen to South America

Have a flexible travel schedule? Discover the best time to fly to South America from McAllen with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from McAllen to South America

What is the cheapest month to book a flight from McAllen to South America?

Currently, February is the cheapest month in which you can book a flight from McAllen to South America (average of $441). Flying from McAllen to South America in December is currently the most expensive (average of $1,516). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFE to SA?

Find hourly flight availability from McAllen to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s optimal to fly from McAllen to South America in the evening. By choosing this option you can save up to 39% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated October 30, 2025.
Get a feel of what it's like to fly with United Airlines and American Airlines from McAllen to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

6.6

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Food

6.6

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Food

6.6

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from McAllen to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from McAllen to South America?

    Located just 2.0 mi from the city center, McAllen Miller Intl (MFE) is the airport most travelers will use when flying to South America from McAllen.

  • How long is the flight from McAllen to South America?

    Departing from McAllen to South America will take you 13h 20m. The distance from McAllen to South America is about 1838 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from McAllen to South America?

  • Can I find deals for flights from McAllen to South America that include hotel bookings?

    Yes. In addition to deals on McAllen to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from McAllen to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from McAllen to South America.

  • Can I find deals for business class flights from McAllen to South America?

    Yes. Cheapflights offers flight deals from McAllen to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from McAllen to South America?

    Currently, February is the cheapest month in which you can book a flight from McAllen to South America (average of $441). Flying from McAllen to South America in December is currently the most expensive (average of $1,516). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for McAllen to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from McAllen to South America

Discover the top 2 airlines that operate flights from McAllen to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$429Average$610FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$443Average$692FlexibilityNo cancel feeOn-time71%

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