South America

$110+ Cheap flights from Cleveland (CLE) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/14. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — BOG
Mar 26 — Apr 21
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Cheap flight deals from Cleveland to South America

Cheapest flights from Cleveland to South America
Explore the most affordable flight options available from Cleveland to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 24, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:38 pm
CLE
-
CTG
1 stop20h 28m
Multiple Airlines
Wed 4/151:11 pm
CTG
-
CLE
1 stop23h 03m
Multiple Airlines
Deal found 2/21$316
This Cheapflightsfares deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:35 pm
CLE
-
MDE
1 stop7h 41m
Spirit Airlines
Tue 5/121:11 am
MDE
-
CLE
1 stop14h 19m
Spirit Airlines
Deal found 2/20$317
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:44 pm
CLE
-
CTG
1 stop19h 26m
Multiple Airlines
Thu 3/52:21 pm
CTG
-
CLE
1 stop10h 17m
Multiple Airlines
Deal found 2/22$322
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:47 pm
CLE
-
MDE
1 stop8h 34m
Multiple Airlines
Wed 4/151:11 am
MDE
-
CLE
1 stop11h 03m
Multiple Airlines
Deal found 2/22$326
This Expedia deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:31 pm
CLE
-
MDE
1 stop6h 50m
Spirit Airlines
Mon 4/201:11 am
MDE
-
CLE
1 stop14h 19m
Spirit Airlines
Deal found 2/22$328
This CheapOair deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:04 pm
CLE
-
BOG
1 stop19h 06m
Spirit Airlines
Mon 3/92:05 pm
BOG
-
CLE
1 stop27h 04m
Spirit Airlines
Deal found 2/22$331
This Cheapflightsfares deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:35 pm
CLE
-
MDE
1 stop7h 41m
Spirit Airlines
Fri 5/151:11 am
MDE
-
CLE
1 stop14h 19m
Spirit Airlines
Deal found 2/20$337
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:00 pm
CLE
-
CTG
2 stops18h 05m
Multiple Airlines
Tue 4/281:11 pm
CTG
-
CLE
1 stop25h 25m
Multiple Airlines
Deal found 2/21$338
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:15 am
CLE
-
MDE
1 stop17h 01m
Multiple Airlines
Tue 5/121:11 am
MDE
-
CLE
1 stop13h 05m
Multiple Airlines
Deal found 2/20$342
This CheapOair deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:04 pm
CLE
-
BOG
1 stop19h 06m
Spirit Airlines
Tue 3/172:10 pm
BOG
-
CLE
1 stop26h 03m
Spirit Airlines
Deal found 2/22$346
This Orbitz deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:31 pm
CLE
-
MDE
1 stop6h 50m
Spirit Airlines
Mon 4/131:17 am
MDE
-
CLE
1 stop14h 56m
Spirit Airlines
Deal found 2/23$348
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:47 pm
CLE
-
BOG
1 stop21h 24m
Multiple Airlines
Thu 4/162:07 pm
BOG
-
CLE
1 stop25h 23m
Multiple Airlines
Deal found 2/22$352

Find flight deals from Cleveland to South America

Keep the following information in mind while searching for Cleveland to South America flight deals. Data was last updated February 24, 2026.

Round-trip from

$316
(Kiwi.com)

One-way from

$110
(FlightHub)

Popular in

March

Cheapest in

August

Average price

$729
From Cleveland Hopkins Intl to South America
One-way flight from Cleveland Hopkins Intl to South America
High demand for flights, 0% potential price rise
Cheapest flight prices on average. 1% potential price decrease ($14 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 24, 2026.
Use the filters below to find and compare flights from Cleveland to South America that are best for you.

Fly from

Cleveland

Fly to

South America

Route

Depart

Return

Price

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Sat 4/11

5:22 pm-12:06 pm

1 stop19h 44m

Cartagena Rafael Nunez

Sun 4/19

1:11 pm-4:30 pm

1 stop26h 19m

$363

ClevelandBogotá

CLE - BOG

CLEBOG

Cleveland Hopkins Intl

Tue 3/31

6:31 pm-1:11 pm

1 stop19h 40m

Bogotá El Dorado

Tue 4/7

2:10 pm-5:13 pm

1 stop26h 03m

$396

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Tue 8/4

5:35 pm-9:25 pm

1 stop28h 50m

Medellín Jose Maria Cordova Intl

Tue 8/11

1:00 pm-4:29 pm

1 stop26h 29m

$441

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Thu 5/21

5:35 pm-9:25 pm

1 stop28h 50m

Medellín Jose Maria Cordova Intl

Sat 5/30

1:00 pm-4:30 pm

1 stop26h 30m

$475

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Wed 3/18

6:31 pm-11:57 am

2 stops18h 26m

Cartagena Rafael Nunez

Mon 3/23

7:15 am-5:13 pm

3 stops32h 58m

$490

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Mon 4/13

6:31 pm-12:52 pm

2 stops19h 21m

Medellín Jose Maria Cordova Intl

Tue 4/21

10:51 am-4:30 pm

3 stops28h 39m

$513

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Wed 8/5

5:35 pm-9:25 pm

1 stop28h 50m

Medellín Jose Maria Cordova Intl

Wed 8/12

1:00 pm-4:29 pm

1 stop26h 29m

$519

ClevelandBogotá

CLE - BOG

CLEBOG

Cleveland Hopkins Intl

Mon 3/23

6:45 pm-1:11 pm

1 stop19h 26m

Bogotá El Dorado

Mon 3/30

4:05 pm-7:42 am

1 stop14h 37m

$535

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Wed 3/18

4:40 pm-11:57 am

2 stops20h 17m

Cartagena Rafael Nunez

Tue 3/24

1:14 pm-11:28 pm

1 stop9h 14m

$544

ClevelandLima

CLE - LIM

CLELIM

Cleveland Hopkins Intl

Mon 3/9

7:04 pm-9:35 pm

1 stop27h 31m

Lima J Chavez Intl

Wed 3/18

10:35 pm-5:13 pm

1 stop17h 38m

$550

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/22

Showing 1-10 of 60 results
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Best time to book a flight from Cleveland to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to South America

What is the cheapest month to book a flight from Cleveland to South America?

Currently, May is the cheapest month in which you can book a flight from Cleveland to South America (average of $239). Flying from Cleveland to South America in December is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 24, 2026.
See what other customers who have flown with Delta, LATAM Airlines, and Copa Airlines from Cleveland to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Cleveland to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Cleveland to South America?

    Cleveland Hopkins Intl (CLE) is the airport you will fly out of if you book a flight from Cleveland to South America. It is only a 10.1 mi journey to Hopkins Intl (CLE) from Cleveland’s city center.

  • How long is the flight from Cleveland to South America?

    A quick flight from Cleveland to South America can take about 16h 35m. Spirit Airlines provides one of the quickest options available for as low as $665. The distance from Cleveland to South America is about 3702 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Cleveland to South America one-way?

    One-way options have recently been found by users for as low as $244 on Copa Airlines. Other airlines that offer cheap prices include Delta from $245 and American Airlines from $350 one-way.

  • What are the most popular routes from Cleveland to South America?

  • Can I find deals for flights from Cleveland to South America that include hotel bookings?

    Yes. In addition to deals on Cleveland to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to South America.

  • Can I find deals for business class flights from Cleveland to South America?

    Yes. Cheapflights offers flight deals from Cleveland to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to South America?

    Currently, May is the cheapest month in which you can book a flight from Cleveland to South America (average of $239). Flying from Cleveland to South America in December is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Cleveland to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Cleveland to South America

Discover the top 5 airlines that operate flights from Cleveland to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$413Average$904FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$462Average$730FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$469Average$824FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$472Average$853FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$536Average$788FlexibilityNo cancel feeOn-time70%

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