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$263+ Cheap flights from Ohio to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — SCL
Mar 8 — Mar 151
Sun 3/8
Sun 3/15
1 adult, Economy
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Cheap flight deals from Ohio to Santiago

Cheapest flights from Ohio to Santiago
Explore the most affordable flight options available from Ohio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 6, 2026.

This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:00 am
DTW
-
SCL
3 stops27h 39m
Multiple Airlines
Tue 4/712:40 am
SCL
-
DTW
3 stops23h 19m
Multiple Airlines
Deal found 2/3$603
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:00 am
PIT
-
SCL
2 stops27h 39m
Multiple Airlines
Thu 3/2611:24 am
SCL
-
PIT
2 stops23h 14m
Multiple Airlines
Deal found 2/2$618
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:20 am
DTW
-
SCL
2 stops24h 20m
Multiple Airlines
Fri 3/2711:24 am
SCL
-
DTW
3 stops30h 46m
Multiple Airlines
Deal found 2/3$621
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/224:09 pm
DTW
-
SCL
2 stops36h 05m
Multiple Airlines
Sun 3/2910:30 am
SCL
-
DTW
1 stop26h 50m
Multiple Airlines
Deal found 2/4$626
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:05 am
DTW
-
SCL
3 stops27h 34m
Multiple Airlines
Thu 3/2611:24 am
SCL
-
DTW
3 stops29h 26m
Multiple Airlines
Deal found 2/2$629
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:20 am
DTW
-
SCL
2 stops24h 20m
Multiple Airlines
Tue 3/3111:00 pm
SCL
-
DTW
1 stop14h 20m
Multiple Airlines
Deal found 2/3$640
This Mytrip deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:05 am
DTW
-
SCL
3 stops22h 09m
Multiple Airlines
Sat 3/285:50 am
SCL
-
DTW
2 stops19h 09m
Multiple Airlines
Deal found 2/4$652
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:00 am
PIT
-
SCL
2 stops27h 39m
Multiple Airlines
Fri 3/2711:24 am
SCL
-
PIT
2 stops23h 14m
Multiple Airlines
Deal found 2/3$664
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:45 am
CMH
-
SCL
2 stops27h 54m
Multiple Airlines
Fri 3/2711:24 am
SCL
-
CMH
2 stops23h 17m
Multiple Airlines
Deal found 2/3$676
This Mytrip deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:00 am
PIT
-
SCL
2 stops22h 01m
Multiple Airlines
Wed 5/277:45 am
SCL
-
PIT
3 stops33h 01m
Multiple Airlines
Deal found 2/4$692
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/51:07 pm
CVG
-
SCL
3 stops41h 08m
Multiple Airlines
Thu 3/1211:25 pm
SCL
-
CVG
1 stop13h 41m
Multiple Airlines
Deal found 2/3$699
This Air Canada deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:55 pm
PIT
-
SCL
1 stop16h 20m
Air Canada
Wed 3/187:55 pm
SCL
-
PIT
1 stop22h 21m
Air Canada
Deal found 2/2$707

Find flight deals from Ohio to Santiago

Keep the following information in mind while searching for Ohio to Santiago flight deals. Data was last updated February 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$603
(Mytrip)

One-way from

$263
(Trip.com)

Popular in

April

Cheapest in

January

Average price

$954
Provider with most accurate pricing for Cleveland Hopkins Intl-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Santiago Arturo Merino Benitez flights.
Search Deals
From Ohio to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Ohio to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from Ohio to Santiago that are best for you.

Fly from

Ohio

Fly to

Santiago

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 3/25

6:00 am-10:39 am

3 stops27h 39m

Santiago Arturo Merino Benitez

Tue 4/7

12:40 am-11:59 pm

3 stops23h 19m

$603

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 3/20

5:20 am-12:00 pm

3 stops29h 40m

Santiago Arturo Merino Benitez

Fri 3/27

11:24 am-5:10 pm

3 stops30h 46m

$621

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 3/19

5:45 am-10:39 am

2 stops27h 54m

Santiago Arturo Merino Benitez

Thu 3/26

11:24 am-3:12 pm

2 stops28h 48m

$636

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Thu 3/19

6:00 am-10:39 am

2 stops27h 39m

Santiago Arturo Merino Benitez

Thu 3/26

11:24 am-9:38 am

2 stops23h 14m

$641

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 3/21

6:00 am-2:40 pm

3 stops31h 40m

Santiago Arturo Merino Benitez

Fri 3/27

1:35 am-11:59 pm

3 stops23h 24m

$653

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Fri 3/20

5:55 pm-11:15 am

1 stop16h 20m

Santiago Arturo Merino Benitez

Fri 3/27

11:24 am-9:38 am

2 stops23h 14m

$661

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Fri 3/20

5:45 am-10:39 am

2 stops27h 54m

Santiago Arturo Merino Benitez

Fri 3/27

11:24 am-9:41 am

2 stops23h 17m

$676

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Mon 5/18

6:00 am-4:01 am

2 stops22h 01m

Santiago Arturo Merino Benitez

Wed 5/27

7:45 am-4:46 pm

3 stops33h 01m

$692

CincinnatiSantiago

CVG - SCL

CVGSCL

Cincinnati Cinci./N. Kentucky

Thu 3/5

1:07 pm-8:15 am

3 stops41h 08m

Santiago Arturo Merino Benitez

Thu 3/12

11:25 pm-12:06 pm

1 stop13h 41m

$699

ColumbusSantiago

CMH - SCL

CMHSCL

Columbus

Mon 5/4

6:25 am-4:01 am

2 stops21h 36m

Santiago Arturo Merino Benitez

Thu 5/14

5:01 am-10:13 pm

3 stops41h 12m

$709

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/5

Showing 1-10 of 56 results
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Best time to book a flight from Ohio to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Santiago

What is the cheapest month to book a flight from Ohio to Santiago?

Currently, November is the cheapest month in which you can book a flight from Ohio to Santiago (average of $549). Flying from Ohio to Santiago in December is currently the most expensive (average of $843). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Ohio to Santiago?

Related info for your journey

Find useful and relevant information for your journey from Ohio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Ohio?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez (SCL) is the airport most travelers will use when flying to Santiago from Ohio.

  • How long is the flight from Ohio to Santiago?

    Airlines like Air Canada, LATAM Airlines, and United Airlines fly from Ohio to Santiago in about 16h 05m. The time it takes to get you to your destination can typically vary by up to 28h 05m. Airlines will cover a distance of 5212 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Ohio to Santiago?

    When deciding which route to take from Ohio to Santiago consider Pittsburgh - Santiago Arturo Merino Benitez, Cleveland Hopkins Intl - Santiago Arturo Merino Benitez or Detroit Metropolitan Wayne County - Santiago Arturo Merino Benitez as they are the most popular.

  • Can I find deals for flights from Ohio to Santiago that include hotel bookings?

    Yes. In addition to deals on Ohio to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Santiago.

  • Can I find deals for business class flights from Ohio to Santiago?

    Yes. Cheapflights offers flight deals from Ohio to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Ohio to Santiago (average of $549). Flying from Ohio to Santiago in December is currently the most expensive (average of $843). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Ohio to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Ohio to Santiago

Discover the top 2 airlines that operate flights from Ohio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$549Average$886FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$608Average$928FlexibilityNo cancel feeOn-time81%

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