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$222+ Cheap flights from Ohio to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — SCL
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Ohio to Santiago

Cheapest flights from Ohio to Santiago
Explore the most affordable flight options available from Ohio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This LATAM Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:32 amCVG - SCL
1 stop20h 38mLATAM Airlines
Sun 12/289:30 pmSCL - CVG
1 stop14h 07mLATAM Airlines
Deal found 12/14$854
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:32 amCVG - SCL
2 stops17h 03mDelta
Tue 12/309:30 pmSCL - CVG
1 stop14h 07mDelta
Deal found 12/16$865
This SmartFares deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:06 pmCVG - SCL
1 stop34h 04mLATAM Airlines
Sun 12/2811:10 pmSCL - CVG
1 stop16h 03mLATAM Airlines
Deal found 12/14$881
This Mytrip deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:43 amCLE - SCL
2 stops16h 17mMultiple Airlines
Thu 1/2912:35 pmSCL - CLE
2 stops31h 31mMultiple Airlines
Deal found 12/17$966
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:55 pmCLE - SCL
1 stop15h 55mUnited Airlines
Thu 1/2910:45 pmSCL - CLE
1 stop14h 23mUnited Airlines
Deal found 12/17$974
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:30 pmDTW - SCL
1 stop14h 20mUnited Airlines
Wed 12/3110:45 pmSCL - DTW
2 stops24h 13mUnited Airlines
Deal found 12/16$1,039
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:49 amDTW - SCL
2 stops25h 01mUnited Airlines
Tue 12/3010:45 pmSCL - DTW
1 stop26h 58mUnited Airlines
Deal found 12/16$1,052
This Orbitz deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:58 pmCLE - SCL
1 stop34h 12mLATAM Airlines
Thu 1/298:50 amSCL - CLE
2 stops17h 46mLATAM Airlines
Deal found 12/17$1,074
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:12 amDTW - SCL
2 stops21h 38mUnited Airlines
Mon 12/2910:45 pmSCL - DTW
2 stops24h 13mUnited Airlines
Deal found 12/16$1,089
This KAYAK deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:32 amCVG - SCL
2 stops17h 03mLATAM Airlines
Tue 12/308:15 amSCL - CVG
2 stops18h 09mLATAM Airlines
Deal found 12/16$1,160
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:00 amCVG - SCL
2 stops47h 50mUnited Airlines
Tue 12/3010:45 pmSCL - CVG
2 stops47h 33mUnited Airlines
Deal found 12/16$1,165
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:23 pmDTW - SCL
1 stop34h 12mMultiple Airlines
Mon 1/511:10 pmSCL - DTW
2 stops35h 41mMultiple Airlines
Deal found 12/15$1,233

Find flight deals from Ohio to Santiago

Keep the following information in mind while searching for Ohio to Santiago flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$630
(Kiwi.com)

One-way from

$222
(Mytrip)

Popular in

December

Cheapest in

January

Average price

$1,174
Provider with most accurate pricing for Cleveland Hopkins Intl-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Santiago Arturo Merino Benitez flights.
Search Deals
From Ohio to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Ohio to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Ohio to Santiago that are best for you.

Fly from

Ohio

Fly to

Santiago

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 1/14

6:35 am-10:39 am

3 stops26h 04m

Santiago Arturo Merino Benitez

Sun 1/25

11:24 am-1:30 pm

3 stops28h 06m

$664

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 1/15

5:05 am-2:40 pm

3 stops31h 35m

Santiago Arturo Merino Benitez

Sun 1/25

11:24 am-10:05 am

2 stops24h 41m

$677

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 1/8

10:27 am-5:35 am

1 stop17h 08m

Santiago Arturo Merino Benitez

Sun 1/25

11:24 am-10:05 am

2 stops24h 41m

$681

CincinnatiSantiago

CVG - SCL

CVGSCL

Cincinnati Cinci./N. Kentucky

Thu 1/29

11:45 am-6:55 am

1 stop17h 10m

Santiago Arturo Merino Benitez

Thu 2/5

11:30 pm-5:09 pm

1 stop19h 39m

$699

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Tue 2/17

6:16 pm-12:15 pm

3 stops39h 59m

Santiago Arturo Merino Benitez

Wed 3/11

11:25 pm-11:27 pm

1 stop25h 02m

$713

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Mon 3/9

11:30 am-5:55 am

1 stop17h 25m

Santiago Arturo Merino Benitez

Wed 3/18

10:30 pm-4:45 pm

1 stop19h 15m

$722

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Thu 2/19

4:25 pm-2:05 pm

2 stops19h 40m

Santiago Arturo Merino Benitez

Tue 3/10

10:30 pm-11:45 am

1 stop14h 15m

$732

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Sun 3/8

12:04 pm-5:55 am

1 stop16h 51m

Santiago Arturo Merino Benitez

Thu 3/26

10:30 pm-4:28 pm

1 stop18h 58m

$735

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Mon 3/9

6:00 am-7:50 am

1 stop24h 50m

Santiago Arturo Merino Benitez

Wed 3/18

9:45 pm-4:16 pm

1 stop19h 31m

$745

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Sun 2/1

6:00 am-9:59 am

2 stops25h 59m

Santiago Arturo Merino Benitez

Sun 2/8

11:24 am-9:40 am

2 stops24h 16m

$749

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 50 results
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Best time to book a flight from Ohio to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Santiago

What is the cheapest month to book a flight from Ohio to Santiago?

Currently, November is the cheapest month in which you can book a flight from Ohio to Santiago (average of $549). Flying from Ohio to Santiago in June is currently the most expensive (average of $844). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SCL?

Find hourly flight availability from Ohio to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

When flying from Ohio to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 25% versus a flight at noon.

What is the cheapest day to fly from Ohio to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Ohio to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Ohio to Santiago flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Ohio to Santiago?

Related info for your journey

Find useful and relevant information for your journey from Ohio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Ohio?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez (SCL) is the airport most travelers will use when flying to Santiago from Ohio.

  • How long is the flight from Ohio to Santiago?

    Airlines like LATAM Airlines, United Airlines, and American Airlines fly from Ohio to Santiago in about 17h 10m. The time it takes to get you to your destination can typically vary by up to 7h 40m. Airlines will cover a distance of 5080 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Ohio to Santiago?

    When deciding which route to take from Ohio to Santiago consider Cleveland Hopkins Intl - Santiago Arturo Merino Benitez, Detroit Metropolitan Wayne County - Santiago Arturo Merino Benitez or Cincinnati Cinci./N. Kentucky - Santiago Arturo Merino Benitez as they are the most popular.

  • Can I find deals for flights from Ohio to Santiago that include hotel bookings?

    Yes. In addition to deals on Ohio to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Santiago.

  • Can I find deals for business class flights from Ohio to Santiago?

    Yes. Cheapflights offers flight deals from Ohio to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Ohio to Santiago (average of $549). Flying from Ohio to Santiago in June is currently the most expensive (average of $844). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Ohio to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Ohio to Santiago

Discover the top 2 airlines that operate flights from Ohio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$549Average$899FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$608Average$950FlexibilityNo cancel feeOn-time81%

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