$205+ Cheap flights from Illinois to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — SCL
Mar 14 — Mar 211
1 adult, Economy
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Find cheap flights from Illinois to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Illinois to Santiago
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Cheapest flights from Illinois to SantiagoExplore the most affordable flight options available from Illinois to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
Explore the most affordable flight options available from Illinois to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
This Mytrip deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:55 am
ORD
- SCL
3 stops33h 20m
Multiple Airlines
Mon 3/239:05 pm
SCL
- ORD
2 stops23h 26m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$514
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/114:51 pm
ORD
- SCL
2 stops43h 39m
Multiple Airlines
Wed 4/1511:00 pm
SCL
- ORD
1 stop25h 59m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$519
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:36 pm
ORD
- SCL
2 stops52h 33m
Multiple Airlines
Mon 4/611:00 pm
SCL
- ORD
1 stop35h 50m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$521
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:56 am
ORD
- SCL
1 stop13h 43m
Multiple Airlines
Sun 4/128:20 pm
SCL
- ORD
2 stops38h 30m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$526
This Copa Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:06 am
ORD
- SCL
1 stop13h 37m
Copa Airlines
Tue 5/264:41 am
SCL
- ORD
1 stop21h 34m
Copa Airlines
Deal found 2/10![Copa Airlines logo]()
$528
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:20 pm
ORD
- SCL
1 stop17h 45m
American Airlines
Wed 4/228:35 pm
SCL
- ORD
1 stop15h 29m
American Airlines
Deal found 2/10![American Airlines logo]()
$529
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:15 pm
ORD
- SCL
2 stops33h 15m
Multiple Airlines
Fri 5/2911:00 pm
SCL
- ORD
1 stop20h 15m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$534
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:34 pm
ORD
- SCL
2 stops25h 31m
Multiple Airlines
Sun 5/2410:55 pm
SCL
- ORD
1 stop19h 40m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$536
This Avianca deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:20 pm
ORD
- SCL
1 stop13h 55m
Avianca
Fri 4/246:40 am
SCL
- ORD
1 stop15h 40m
Avianca
Deal found 2/9![Avianca logo]()
$537
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:52 pm
ORD
- SCL
2 stops28h 13m
Multiple Airlines
Fri 5/2911:00 pm
SCL
- ORD
1 stop20h 15m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$538
This Copa Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/168:34 am
ORD
- SCL
1 stop13h 15m
Copa Airlines
Tue 3/3112:28 pm
SCL
- ORD
1 stop14h 41m
Copa Airlines
Deal found 2/9![Copa Airlines logo]()
$539
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:23 pm
MDW
- SCL
2 stops16h 52m
Delta
Sun 5/248:40 pm
SCL
- MDW
1 stop16h 16m
Delta
Deal found 2/10![Delta logo]()
$545
Best flights from Illinois to SantiagoDiscover carefully curated flight deals from Illinois to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
Discover carefully curated flight deals from Illinois to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
This Copa Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:06 am
ORD
- SCL
1 stop13h 37m
Copa Airlines
Wed 4/2211:25 am
SCL
- ORD
1 stop14h 48m
Copa Airlines
Deal found 2/9![Copa Airlines logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/114:51 pm
ORD
- SCL
2 stops43h 39m
Multiple Airlines
Wed 4/1511:00 pm
SCL
- ORD
1 stop25h 59m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$519
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:23 pm
MDW
- SCL
2 stops16h 52m
Delta
Tue 5/268:40 pm
SCL
- MDW
1 stop14h 11m
Delta
Deal found 2/10![Delta logo]()
$545
This LATAM Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 am
STL
- SCL
2 stops21h 35m
LATAM Airlines
Mon 3/234:35 am
SCL
- STL
2 stops21h 23m
LATAM Airlines
Deal found 2/10![LATAM Airlines logo]()
$830
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:17 am
STL
- SCL
2 stops21h 33m
United Airlines
Mon 3/239:45 pm
SCL
- STL
2 stops25h 22m
United Airlines
Deal found 2/11![United Airlines logo]()
$851
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:00 am
STL
- SCL
1 stop22h 00m
American Airlines
Mon 3/239:20 pm
SCL
- STL
1 stop15h 12m
American Airlines
Deal found 2/11![American Airlines logo]()
$860
This Copa Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:06 am
ORD
- SCL
1 stop17h 54m
Copa Airlines
Tue 4/1412:09 am
SCL
- ORD
1 stop14h 49m
Copa Airlines
Deal found 2/11![Copa Airlines logo]()
$517
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:21 pm
MDW
- SCL
1 stop12h 54m
Delta
Thu 5/288:40 pm
SCL
- MDW
1 stop16h 16m
Delta
Deal found 2/10![Delta logo]()
$545
This Copa Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:02 am
ORD
- SCL
1 stop14h 24m
Copa Airlines
Mon 5/254:09 am
SCL
- ORD
1 stop22h 06m
Copa Airlines
Deal found 2/9![Copa Airlines logo]()
$539
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:21 pm
MDW
- SCL
1 stop12h 54m
Delta
Tue 5/268:40 pm
SCL
- MDW
2 stops17h 02m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:23 pm
MDW
- SCL
2 stops16h 52m
Delta
Thu 5/288:40 pm
SCL
- MDW
1 stop16h 16m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:53 pm
MDW
- SCL
1 stop17h 22m
Delta
Tue 5/268:40 pm
SCL
- MDW
1 stop14h 11m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:21 pm
MDW
- SCL
1 stop12h 54m
Delta
Thu 5/288:40 pm
SCL
- MDW
1 stop16h 16m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:21 pm
MDW
- SCL
1 stop12h 54m
Delta
Thu 5/288:40 pm
SCL
- MDW
1 stop16h 16m
Delta
Deal found 2/10![Delta logo]()
$545
This LATAM Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2012:04 pm
STL
- SCL
1 stop17h 36m
LATAM Airlines
Mon 3/3011:00 pm
SCL
- STL
2 stops20h 53m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$893
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:21 pm
MDW
- SCL
1 stop12h 54m
Delta
Sun 5/248:40 pm
SCL
- MDW
1 stop14h 11m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:53 pm
MDW
- SCL
1 stop17h 22m
Delta
Sun 5/248:40 pm
SCL
- MDW
1 stop14h 11m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:53 pm
ORD
- SCL
1 stop12h 22m
Delta
Thu 5/288:40 pm
SCL
- ORD
1 stop14h 26m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:06 pm
ORD
- SCL
1 stop16h 44m
Delta
Mon 5/2510:55 pm
SCL
- ORD
1 stop19h 40m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/252:25 pm
ORD
- SCL
1 stop15h 50m
Delta
Mon 5/2511:00 pm
SCL
- ORD
2 stops18h 49m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:53 pm
ORD
- SCL
1 stop12h 22m
Delta
Tue 5/268:40 pm
SCL
- ORD
1 stop14h 26m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:53 pm
ORD
- SCL
1 stop12h 22m
Delta
Thu 5/288:40 pm
SCL
- ORD
2 stops17h 21m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:53 pm
ORD
- SCL
1 stop12h 22m
Delta
Mon 5/2510:55 pm
SCL
- ORD
1 stop19h 40m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:53 pm
ORD
- SCL
1 stop12h 22m
Delta
Mon 5/2510:55 pm
SCL
- ORD
1 stop19h 40m
Delta
Deal found 2/10![Delta logo]()
$545
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:12 am
STL
- SCL
1 stop19h 28m
Delta
Mon 3/236:30 pm
SCL
- STL
2 stops18h 39m
Delta
Deal found 2/9![Delta logo]()
$858
Last-minute flights from Illinois to SantiagoDiscover last-minute flight deals from Illinois to Santiago. Data last updated February 12, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to Santiago. Data last updated February 12, 2026 and is based on user searches.
This LATAM Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/812:47 pm
MDW
- SCL
1 stop16h 53m
LATAM Airlines
Wed 3/114:20 pm
SCL
- MDW
2 stops32h 11m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$551
This FlightHub deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/910:40 am
ORD
- SCL
1 stop17h 15m
LATAM Airlines
Thu 3/1910:40 pm
SCL
- ORD
1 stop20h 30m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$540
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/92:10 pm
ORD
- SCL
1 stop15h 40m
United Airlines
Wed 3/119:45 pm
SCL
- ORD
1 stop17h 03m
United Airlines
Deal found 2/8![United Airlines logo]()
$551
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:00 pm
ORD
- SCL
2 stops15h 05m
American Airlines
Tue 3/1710:15 pm
SCL
- ORD
1 stop21h 30m
American Airlines
Deal found 2/10![American Airlines logo]()
$556
This Copa Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/168:34 am
ORD
- SCL
1 stop13h 15m
Copa Airlines
Tue 3/3112:28 pm
SCL
- ORD
1 stop14h 41m
Copa Airlines
Deal found 2/9![Copa Airlines logo]()
$539
This Mytrip deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:55 am
ORD
- SCL
3 stops33h 20m
Multiple Airlines
Mon 3/239:05 pm
SCL
- ORD
2 stops23h 26m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$514
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:36 pm
ORD
- SCL
2 stops52h 33m
Multiple Airlines
Mon 4/611:00 pm
SCL
- ORD
1 stop35h 50m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$521
This LATAM Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:10 am
ORD
- SCL
2 stops16h 25m
LATAM Airlines
Mon 4/611:00 pm
SCL
- ORD
2 stops19h 10m
LATAM Airlines
Deal found 2/10![LATAM Airlines logo]()
$534
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2510:45 am
MDW
- SCL
2 stops16h 50m
Delta
Sun 4/58:40 pm
SCL
- MDW
1 stop16h 22m
Delta
Deal found 2/10![Delta logo]()
$556
This KAYAK deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/295:59 pm
ORD
- SCL
2 stops22h 11m
LATAM Airlines
Tue 3/3110:10 pm
SCL
- ORD
2 stops27h 44m
LATAM Airlines
Deal found 2/10![LATAM Airlines logo]()
$553
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:56 am
ORD
- SCL
1 stop13h 43m
Multiple Airlines
Sun 4/128:20 pm
SCL
- ORD
2 stops38h 30m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$526
This KAYAK deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:07 pm
MDW
- SCL
2 stops25h 37m
LATAM Airlines
Sun 4/58:40 pm
SCL
- MDW
1 stop16h 22m
LATAM Airlines
Deal found 2/10![LATAM Airlines logo]()
$553
One-way flights from Illinois to SantiagoSearch for one-way flight options from Illinois to Santiago. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
Search for one-way flight options from Illinois to Santiago. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/193:52 pm
ORD
- SCL
2 stops28h 13m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$205
This Trip.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1610:55 am
ORD
- SCL
3 stops23h 05m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/309:42 pm
MDW
- SCL
2 stops22h 33m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/24:51 pm
ORD
- SCL
2 stops27h 14m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/174:51 pm
ORD
- SCL
2 stops35h 49m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/104:09 pm
MDW
- SCL
3 stops27h 56m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$236
This Mytrip deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:55 am
ORD
- SCL
2 stops25h 35m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$244
This FlightHub deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:10 am
ORD
- SCL
2 stops16h 25m
LATAM Airlines
Deal found 2/10![LATAM Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/12:56 pm
MDW
- SCL
3 stops37h 34m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:46 pm
MDW
- SCL
3 stops35h 44m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$251
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:10 am
ORD
- SCL
2 stops20h 45m
Delta
Deal found 2/9![Delta logo]()
$252
This Copa Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:06 am
ORD
- SCL
1 stop14h 20m
Copa Airlines
Deal found 2/10![Copa Airlines logo]()
$253
Find flight deals from Illinois to Santiago
Keep the following information in mind while searching for Illinois to Santiago flight deals. Data was last updated February 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $514 (Mytrip) |
One-way from | $205 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $821 |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Illinois to Santiago that are best for you.
Fly from
Illinois
Fly to
Santiago
Route
Depart
Return
Price
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Mon 4/13
8:06 am-10:43 pm
1 stop13h 37m
Santiago Arturo Merino Benitez
Wed 4/22
11:25 am-1:13 am
1 stop14h 48m
$517
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sat 4/11
8:06 am-3:00 am
1 stop17h 54m
Santiago Arturo Merino Benitez
Tue 4/14
12:09 am-1:58 pm
1 stop14h 49m
$517
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Sat 4/11
4:51 pm-1:30 pm
2 stops43h 39m
Santiago Arturo Merino Benitez
Wed 4/15
11:00 pm-11:59 pm
1 stop25h 59m
$519
ChicagoSantiago
ORD - SCL
ORDSCL
Chicago O'Hare Intl
Fri 5/15
8:02 am-11:26 pm
1 stop14h 24m
Santiago Arturo Merino Benitez
Mon 5/25
4:09 am-1:15 am
1 stop22h 06m
$539
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Thu 4/30
1:23 pm-7:15 am
2 stops16h 52m
Santiago Arturo Merino Benitez
Tue 5/26
8:40 pm-9:51 am
1 stop14h 11m
$545
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Mon 4/27
5:21 pm-7:15 am
1 stop12h 54m
Santiago Arturo Merino Benitez
Thu 5/28
8:40 pm-11:56 am
1 stop16h 16m
$545
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Wed 4/29
5:21 pm-7:15 am
1 stop12h 54m
Santiago Arturo Merino Benitez
Tue 5/26
8:40 pm-12:42 pm
2 stops17h 02m
$545
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Thu 4/30
1:23 pm-7:15 am
2 stops16h 52m
Santiago Arturo Merino Benitez
Thu 5/28
8:40 pm-11:56 am
1 stop16h 16m
$545
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Tue 4/28
12:53 pm-7:15 am
1 stop17h 22m
Santiago Arturo Merino Benitez
Tue 5/26
8:40 pm-9:51 am
1 stop14h 11m
$545
ChicagoSantiago
MDW - SCL
MDWSCL
Chicago Midway
Tue 4/28
5:21 pm-7:15 am
1 stop12h 54m
Santiago Arturo Merino Benitez
Thu 5/28
8:40 pm-11:56 am
1 stop16h 16m
$545
Showing 1-10 of 55 results
Best time to book a flight from Illinois to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Illinois with our price prediction graph.
ORD-SCL
MDW-SCL
STL-SCL
MLI-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to Santiago
USIL-SCL
ORD-SCL
MDW-SCL
STL-SCL
MLI-SCL
What is the cheapest month to book a flight from Illinois to Santiago?
Currently, January is the cheapest month in which you can book a flight from Illinois to Santiago (average of $473). Flying from Illinois to Santiago in August is currently the most expensive (average of $890). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Illinois to Santiago?
Related info for your journey
Find useful and relevant information for your journey from Illinois to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Illinois to Santiago
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to Santiago by cabin class
Find flights from Illinois to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and Santiago flights
Browse other Illinois and Santiago flight options. Last updated on February 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 12, 2026.
Illinois to Santiago flights
Consider these flights traveling from Illinois to Santiago.
Top 7 airlines flying from Illinois to Santiago
Discover the top 7 airlines that operate flights from Illinois to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$484 | Average$951 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$537 | Average$741 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$564 | Average$741 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$583 | Average$873 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$596 | Average$761 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$597 | Average$938 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$687 | Average$813 | FlexibilityNo cancel fee | On-time69% |