$108+ Cheap flights from Iowa to Santa Ana, CA (SNA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SNA
Oct 22 — Oct 291
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Santa Ana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to Santa Ana
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Cheapest flights from Iowa to Santa AnaExplore the most affordable flight options available from Iowa to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
Explore the most affordable flight options available from Iowa to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/252:18 pm -
Nonstop3h 38m
Thu 10/294:46 pm -
Nonstop3h 15m
Deal found 9/20![Allegiant Air logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:18 pm -
Nonstop3h 38m
Thu 10/224:46 pm -
Nonstop3h 15m
Deal found 9/22![Allegiant Air logo]()
$231
This Cheapflightsfares deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:22 pm -
Nonstop3h 38m
Sun 11/84:10 pm -
Nonstop3h 17m
Deal found 9/20![Allegiant Air logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:09 pm -
1 stop23h 05m
Thu 10/224:46 pm -
Nonstop3h 15m
Deal found 9/22![Multiple Airlines logo]()
$265
This Cheapflightsfares deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:35 pm -
1 stop16h 48m
Sun 12/612:33 pm -
1 stop5h 17m
Deal found 9/21![Frontier logo]()
$274
This CheapOair deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/181:38 pm -
Nonstop3h 38m
Sun 10/254:46 pm -
Nonstop3h 15m
Deal found 9/18![Allegiant Air logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:18 pm -
Nonstop3h 38m
Tue 10/207:30 am -
1 stop28h 22m
Deal found 9/22![Multiple Airlines logo]()
$294
This CheapOair deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:18 pm -
Nonstop3h 38m
Sun 11/14:46 pm -
Nonstop3h 15m
Deal found 9/22![Allegiant Air logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:25 pm -
2 stops23h 15m
Thu 10/224:46 pm -
Nonstop3h 15m
Deal found 9/22![Multiple Airlines logo]()
$307
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:00 am -
1 stop7h 45m
Sat 12/54:32 pm -
1 stop5h 27m
Deal found 9/21![American Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:19 pm -
1 stop5h 55m
Wed 11/44:32 pm -
1 stop5h 27m
Deal found 9/18![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:30 pm -
1 stop6h 39m
Sat 12/511:05 am -
2 stops9h 40m
Deal found 9/21![United Airlines logo]()
$366
Best flights from Iowa to Santa AnaDiscover carefully curated flight deals from Iowa to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
Discover carefully curated flight deals from Iowa to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:01 am -
2 stops9h 20m
Mon 12/1412:56 pm -
1 stop6h 35m
Deal found 9/17![Delta logo]()
$368
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:00 am -
1 stop5h 05m
Fri 11/62:40 pm -
1 stop5h 25m
Deal found 9/18![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/264:30 pm -
1 stop6h 10m
Tue 3/28:00 am -
2 stops11h 14m
Deal found 9/20![United Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:00 am -
1 stop19h 09m
Thu 12/3111:43 am -
1 stop10h 46m
Deal found 9/20![American Airlines logo]()
$556
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:45 am -
1 stop5h 44m
Mon 10/194:15 pm -
1 stop5h 33m
Deal found 9/18![United Airlines logo]()
$416
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:45 pm -
1 stop5h 15m
Sat 11/146:45 am -
1 stop9h 25m
Deal found 9/17![United Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/186:25 am -
2 stops8h 40m
Fri 1/2210:15 am -
2 stops8h 25m
Deal found 9/20![Southwest logo]()
$470
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:30 am -
1 stop9h 14m
Wed 11/47:00 am -
2 stops12h 56m
Deal found 9/22![Delta logo]()
$474
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:12 am -
2 stops12h 32m
Sat 10/106:22 pm -
2 stops12h 33m
Deal found 9/21![United Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:25 pm -
2 stops10h 40m
Mon 11/92:00 pm -
1 stop7h 09m
Deal found 9/22![Delta logo]()
$483
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:20 am -
2 stops8h 40m
Mon 10/262:35 pm -
1 stop5h 45m
Deal found 9/22![Southwest logo]()
$499
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:04 am -
2 stops15h 06m
Mon 11/98:49 am -
1 stop12h 49m
Deal found 9/22![American Airlines logo]()
$581
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:00 am -
2 stops13h 18m
Sun 12/67:55 am -
2 stops13h 15m
Deal found 9/17![Delta logo]()
$488
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/910:00 am -
2 stops13h 53m
Tue 1/126:45 am -
1 stop8h 26m
Deal found 9/17![United Airlines logo]()
$486
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:04 am -
1 stop17h 20m
Tue 11/1011:40 am -
1 stop9h 58m
Deal found 9/22![American Airlines logo]()
$641
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:14 am -
1 stop7h 45m
Mon 11/211:10 am -
1 stop7h 49m
Deal found 9/19![United Airlines logo]()
$499
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:07 am -
1 stop17h 06m
Sat 10/109:55 am -
2 stops11h 56m
Deal found 9/21![American Airlines logo]()
$651
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:02 am -
2 stops11h 31m
Thu 11/52:22 pm -
1 stop6h 34m
Deal found 9/20![United Airlines logo]()
$504
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:50 am -
2 stops9h 43m
Sun 11/111:10 am -
1 stop7h 26m
Deal found 9/20![United Airlines logo]()
$521
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:45 am -
1 stop5h 44m
Tue 10/134:15 pm -
1 stop5h 33m
Deal found 9/22![United Airlines logo]()
$562
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:30 am -
1 stop7h 11m
Sat 10/101:05 pm -
1 stop5h 46m
Deal found 9/21![United Airlines logo]()
$569
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/167:00 pm -
1 stop25h 20m
Sat 2/206:28 pm -
2 stops12h 46m
Deal found 9/17![United Airlines logo]()
$609
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:12 am -
2 stops12h 32m
Sun 10/116:22 pm -
2 stops12h 33m
Deal found 9/22![United Airlines logo]()
$634
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:12 am -
2 stops12h 32m
Sun 10/258:00 pm -
2 stops10h 39m
Deal found 9/21![United Airlines logo]()
$943
Last-minute flights from Iowa to Santa AnaDiscover last-minute flight deals from Iowa to Santa Ana. Data last updated September 22, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Santa Ana. Data last updated September 22, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:12 am -
2 stops12h 32m
Sat 10/106:22 pm -
2 stops12h 33m
Deal found 9/21![United Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:25 pm -
2 stops20h 38m
Thu 10/224:46 pm -
Nonstop3h 15m
Deal found 9/22![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:18 pm -
Nonstop3h 38m
Thu 10/224:46 pm -
Nonstop3h 15m
Deal found 9/22![Allegiant Air logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:18 pm -
Nonstop3h 38m
Tue 10/207:30 am -
1 stop28h 22m
Deal found 9/22![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:25 pm -
2 stops23h 15m
Thu 10/224:46 pm -
Nonstop3h 15m
Deal found 9/22![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:09 pm -
1 stop23h 05m
Thu 10/224:46 pm -
Nonstop3h 15m
Deal found 9/22![Multiple Airlines logo]()
$265
This CheapOair deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/181:38 pm -
Nonstop3h 38m
Sun 10/254:46 pm -
Nonstop3h 15m
Deal found 9/18![Allegiant Air logo]()
$277
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:19 pm -
1 stop5h 55m
Tue 10/273:30 pm -
1 stop6h 50m
Deal found 9/19![American Airlines logo]()
$399
This Cheapflightsfares deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/252:18 pm -
Nonstop3h 38m
Thu 10/294:46 pm -
Nonstop3h 15m
Deal found 9/20![Allegiant Air logo]()
$221
This CheapOair deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:18 pm -
Nonstop3h 38m
Sun 11/14:46 pm -
Nonstop3h 15m
Deal found 9/22![Allegiant Air logo]()
$297
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:19 pm -
1 stop5h 55m
Wed 11/44:32 pm -
1 stop5h 27m
Deal found 9/18![American Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:45 am -
1 stop6h 48m
Thu 11/54:32 pm -
1 stop5h 27m
Deal found 9/20![American Airlines logo]()
$379
One-way flights from Iowa to Santa AnaSearch for one-way flight options from Iowa to Santa Ana. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
Search for one-way flight options from Iowa to Santa Ana. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
This CheapOair deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:50 pm -
Nonstop3h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Allegiant Air logo]()
$108
This Super.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/111:38 pm -
Nonstop3h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Allegiant Air logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:22 pm -
Nonstop3h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Allegiant Air logo]()
$128
This Super.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/181:38 pm -
Nonstop3h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Allegiant Air logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:09 pm -
1 stop23h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:25 pm -
1 stop21h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:25 pm -
2 stops40h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:30 pm -
2 stops48h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2011:54 am -
1 stop21h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$252
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:58 pm -
1 stop5h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![United Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1910:46 am -
1 stop28h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Allegiant Air logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/188:18 pm -
2 stops38h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Allegiant Air logo]()
$343
Find flight deals from Iowa to Santa Ana
Keep the following information in mind while searching for Iowa to Santa Ana flight deals. Data was last updated September 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $141 (Travelocity) |
One-way from | $115 (Super.com) |
Popular in | August |
Cheapest in | October |
Average price | $384 |
Good round-trip deal | $175 or less |
Good one-way deal | $96 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
Use the filters below to find and compare flights from Iowa to Santa Ana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSanta Ana
DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty
DSMSNA
Des Moines
Sun 10/18
10:09 pm-7:14 pm
1 stop23h 05m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$148
Des MoinesSanta Ana
DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty
DSMSNA
Des Moines
Thu 10/29
10:57 am-10:30 pm
2 stops13h 33m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$173
Des MoinesSanta Ana
DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty
DSMSNA
Des Moines
Sat 10/17
3:02 pm-9:51 pm
1 stop8h 49m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$178
Des MoinesSanta Ana
DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty
DSMSNA
Des Moines
Thu 12/10
4:53 pm-9:04 pm
1 stop6h 11m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$178
Quickest round-trip
Des MoinesSanta Ana
DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty
DSMSNA
Des Moines
Thu 10/29
2:18 pm-3:56 pm
Nonstop3h 38m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$191
Des MoinesSanta Ana
DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty
DSMSNA
Des Moines
Mon 10/19
5:45 am-9:29 am
1 stop5h 44m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$233
Des MoinesSanta Ana
DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty
DSMSNA
Des Moines
Thu 10/29
9:50 am-5:33 pm
2 stops9h 43m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$238
Des MoinesSanta Ana
DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty
DSMSNA
Des Moines
Tue 1/5
1:02 pm-10:14 pm
2 stops11h 12m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$238
Cedar RapidsSanta Ana
CID Cedar Rapids - SNA Santa Ana J. Wayne/Orange Cnty
CIDSNA
Cedar Rapids
Sun 12/20
11:54 am-7:49 am
1 stop21h 55m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$252
Des MoinesSanta Ana
DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty
DSMSNA
Des Moines
Thu 12/24
5:12 pm-9:15 pm
1 stop6h 03m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$267
Showing 1-10 of 47 resultsSorted by cheapest first
Best time to book a flight from Iowa to Santa Ana
Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Iowa with our price prediction graph.
DSM-SNA
CID-SNA
MCW-SNA
SUX-SNA
ALO-SNA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Santa Ana
USIA-SNA
DSM-SNA
CID-SNA
MCW-SNA
SUX-SNA
What is the cheapest month to book a flight from Iowa to Santa Ana, California?
Currently, January is the cheapest month in which you can book a flight from Iowa to Santa Ana, California (average of $266). Flying from Iowa to Santa Ana, California in March is currently the most expensive (average of $477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Iowa to Santa Ana, California?
Airfare is below average for this route at the moment.
Iowa to Santa Ana, California flights typically cost between $174 and $322 in January.The cheapest round-trip price found within the last 5 days was $141 on Allegiant Air (Jan 18-Jan 22).
How far ahead should I book a flight from Iowa to Santa Ana, California?
Booking 90 days in advance of your planned departure date is, on average, the best time to get cheap flights from Iowa to Santa Ana, California. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Iowa to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santa Ana?
Book flights to Santa Ana if you plan to visit one of these locationsTustin
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Alternative routes for Iowa to Santa Ana
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Complete your trip
Complete your trip to Santa Ana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Santa Ana by cabin class
Find flights from Iowa to Santa Ana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Santa Ana flights
Browse other Iowa and Santa Ana flight options. Last updated on September 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santa Ana
Explore flights to Santa Ana departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 22, 2026.
Iowa to Santa Ana flights
Consider these flights traveling from Iowa to Santa Ana.
Top 5 airlines flying from Iowa to Santa Ana
Discover the top 5 airlines that operate flights from Iowa to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$124 | Average$226 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$268 | Average$423 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$269 | Average$522 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$341 | Average$476 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$379 | Average$612 | FlexibilityNo cancel fee | On-timeN/A |