HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Ana

$145+ Cheap flights from Chicago (CHI) to Santa Ana (SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — SNA
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Chicago to Santa Ana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Chicago to Santa Ana J. Wayne/Orange Cnty are usually found in September or May, booked 83 days in advance, depart on a Saturday or Tuesday and return on a Wednesday

Cheap flight deals from Chicago to Santa Ana

Cheapest flights from Chicago to Santa Ana
Explore the most affordable flight options available from Chicago to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:06 pm
ORD
-
SNA
1 stop20h 27m
Multiple Airlines
Sun 4/197:56 pm
SNA
-
ORD
2 stops27h 13m
Multiple Airlines
Deal found 3/18$284
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/83:29 pm
ORD
-
SNA
1 stop22h 05m
Multiple Airlines
Thu 4/163:23 pm
SNA
-
ORD
1 stop12h 02m
Multiple Airlines
Deal found 3/18$285
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/103:21 pm
ORD
-
SNA
2 stops20h 32m
Spirit Airlines
Wed 4/153:23 pm
SNA
-
ORD
1 stop12h 02m
Spirit Airlines
Deal found 3/21$286
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:58 pm
ORD
-
SNA
1 stop22h 58m
Multiple Airlines
Tue 4/217:30 am
SNA
-
ORD
1 stop20h 38m
Multiple Airlines
Deal found 3/18$287
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:40 pm
ORD
-
SNA
Nonstop4h 33m
American Airlines
Tue 4/211:36 pm
SNA
-
ORD
Nonstop4h 23m
American Airlines
Deal found 3/20$289
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:42 pm
ORD
-
SNA
1 stop13h 27m
Multiple Airlines
Wed 5/203:23 pm
SNA
-
ORD
1 stop12h 02m
Multiple Airlines
Deal found 3/18$290
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:48 pm
ORD
-
SNA
1 stop15h 37m
Multiple Airlines
Sun 5/32:42 pm
SNA
-
ORD
1 stop13h 26m
Multiple Airlines
Deal found 3/21$291
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:58 pm
ORD
-
SNA
1 stop22h 58m
Multiple Airlines
Sat 4/187:30 am
SNA
-
ORD
2 stops13h 57m
Multiple Airlines
Deal found 3/19$292
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:42 pm
ORD
-
SNA
2 stops22h 03m
Multiple Airlines
Wed 6/107:30 am
SNA
-
ORD
1 stop19h 55m
Multiple Airlines
Deal found 3/18$294
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:00 pm
ORD
-
SNA
2 stops8h 45m
Spirit Airlines
Wed 5/203:23 pm
SNA
-
ORD
1 stop12h 02m
Spirit Airlines
Deal found 3/21$295
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:50 am
ORD
-
SNA
2 stops30h 54m
Multiple Airlines
Tue 4/213:23 pm
SNA
-
ORD
1 stop12h 45m
Multiple Airlines
Deal found 3/19$296
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:35 pm
MDW
-
SNA
1 stop8h 30m
Southwest
Tue 4/217:40 pm
SNA
-
MDW
1 stop7h 20m
Southwest
Deal found 3/20$309

Find flight deals from Chicago to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$283
(CheapOair)

One-way from

$145
(American Airlines)

Popular in

March

Cheapest in

September

Average price

$454

Good round-trip deal

$343 or less

Good one-way deal

$218 or less
Provider with most accurate pricing for Chicago (CHI)-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Chicago (CHI) to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Chicago (CHI) to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Chicago (CHI) to Santa Ana J. Wayne/Orange Cnty.
Search Deals
Price to beat on a one-way flight from Chicago (CHI) to Santa Ana J. Wayne/Orange Cnty.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Chicago to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Fri 5/1

8:48 pm-10:25 am

1 stop15h 37m

Santa Ana J. Wayne/Orange Cnty

Tue 5/5

12:21 pm-11:59 pm

1 stop9h 38m

$309

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Sat 5/2

1:55 pm-5:45 pm

1 stop5h 50m

Santa Ana J. Wayne/Orange Cnty

Sat 5/9

7:25 pm-5:25 am

1 stop8h 00m

$337

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Mon 4/20

7:54 pm-10:35 pm

Nonstop4h 41m

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

3:29 pm-12:45 am

1 stop7h 16m

$339

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Fri 6/19

5:00 am-9:07 am

1 stop6h 07m

Santa Ana J. Wayne/Orange Cnty

Sat 6/27

4:00 pm-12:44 am

1 stop6h 44m

$340

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Fri 6/5

3:47 pm-8:34 pm

1 stop6h 47m

Santa Ana J. Wayne/Orange Cnty

Mon 6/8

1:55 pm-11:47 pm

1 stop7h 52m

$343

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Tue 6/2

7:45 am-11:55 am

1 stop6h 10m

Santa Ana J. Wayne/Orange Cnty

Tue 6/9

2:05 pm-11:29 pm

1 stop7h 24m

$349

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Tue 4/14

2:09 pm-6:06 pm

1 stop5h 57m

Santa Ana J. Wayne/Orange Cnty

Tue 4/21

9:54 am-6:04 pm

1 stop6h 10m

$349

ChicagoSanta Ana

ORD - SNA

ORDSNA

Chicago O'Hare Intl

Tue 4/7

7:45 am-2:00 pm

1 stop8h 15m

Santa Ana J. Wayne/Orange Cnty

Thu 4/9

2:20 pm-10:55 pm

1 stop6h 35m

$378

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Wed 4/8

5:30 pm-9:50 pm

1 stop6h 20m

Santa Ana J. Wayne/Orange Cnty

Mon 4/13

7:40 pm-5:00 am

1 stop7h 20m

$378

ChicagoSanta Ana

MDW - SNA

MDWSNA

Chicago Midway

Fri 6/19

5:15 am-9:15 am

1 stop6h 00m

Santa Ana J. Wayne/Orange Cnty

Sat 6/20

7:45 pm-5:10 am

1 stop7h 25m

$383

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 43 resultsSorted by cheapest first
1
2
3
...
5

Compare providers for flights from Chicago to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Santa Ana in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago-Santa Ana flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Santa Ana flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Santa Ana flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago-Santa Ana flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Santa Ana flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Chicago to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Santa Ana

How far ahead should I book a flight from Chicago to Santa Ana?

Use this chart to determine the optimal time to book a round-trip flight from Chicago to Santa Ana. Price data was last updated on March 13, 2026.

Booking 25 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago to Santa Ana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Chicago to Santa Ana?

Currently, April is the cheapest month in which you can book a flight from Chicago to Santa Ana (average of $67). Flying from Chicago to Santa Ana in March is currently the most expensive (average of $166). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to SNA?

Find hourly flight availability from Chicago to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 23, 2026.

When flying from Chicago to Santa Ana, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 16% versus a flight at noon.

Weekly flight availability from Chicago to Santa Ana

Explore weekly flight availability from Chicago to Santa Ana. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 23, 2026.

The most flights from CHI to SNA are scheduled on a Monday (20 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (13 on average).

What’s the top layover airport for flights from Chicago to Santa Ana?

Share of 1-stop round-trip flights from Chicago to Santa Ana chosen by Cheapflights users in the past 12 months, using the same layover each way.

Phoenix (PHX) – chosen by Cheapflights users on 67% of 1-stop itineraries from Chicago to Santa Ana on Cheapflights.

What’s the cheapest layover airport for flights from Chicago to Santa Ana?

Average round-trip fare for 1-stop flights from Chicago to Santa Ana, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Phoenix (PHX) is the most affordable 1-stop option, with an average round-trip price of $185.

What’s the fastest layover option from Chicago to Santa Ana?

Shortest average travel time for 1-stop one-way flights from Chicago to Santa Ana, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Las Vegas (LAS) have the shortest average one-way travel time for 1-stop routes: 6h 15m.

Which airport typically offers the quickest layover for flights from Chicago to Santa Ana?

Average layover duration for 1-stop one-way flights from Chicago to Santa Ana, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Las Vegas (LAS) offer the fastest connection on this route, with an average layover time of 1h 40m.

The best insider tips for Chicago to Santa Ana flights

AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Chicago to Santa Ana trip
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on ORD

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Scott Laird

Scott Laird

Expert on SNA

Originally from Anchorage, Alaska, Scott is a frequent contributor to Fodor’s Travel Guide, Conde Nast Traveler, TravelAge West, and TravelPulse. He holds a Bachelor of Science in Organizational Management from Alaska Pacific University and a Master of Science in Airline Management from Embry-Riddle Aeronautical University, and has worked in the airline and hotel industries and as a travel consultant.

Read more

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated March 23, 2026.
Read through reviews of airlines operating flights from Chicago to Santa Ana, such as Southwest,Alaska Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,324 reviews
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Alaska Airlines
7.9
Good
12,098 reviews
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,460 reviews
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,489 reviews
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Spirit Airlines
6.3
Okay
8,538 reviews
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Chicago to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Ana from Chicago?

    Santa Ana J. Wayne/Orange Cnty (SNA), located 4.8 mi from the city center, is the airport you fly into when you book flights from Chicago to Santa Ana. 7 airlines have flights to J. Wayne/Orange Cnty from Chicago on a regular basis. Booking flights from Chicago to Santa Ana J. Wayne/Orange Cnty should not be difficult; the airport handles an average of 17 inbound flights from Chicago per day.

  • How long is the flight from Chicago to Santa Ana?

    Alaska Airlines, Southwest, and United Airlines can get you from Chicago to Santa Ana in just under 4h 41m. Your travel time can differ by up to 10h 56m. The distance from Chicago to Santa Ana is about 1721 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Chicago to Santa Ana round-trip?

    Flying on Spirit Airlines is currently your cheapest option to Santa Ana, with prices starting at $69. Additional round-trip tickets that might be worth considering are offered by Frontier and Alaska Airlines, with the lowest prices starting at $129 and $248, respectively. These flights start at 81% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Chicago to Santa Ana one-way?

    $72 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Spirit Airlines and Delta, with prices starting from $86 and $128, respectively.

  • What are the most reliable airlines from Chicago to Santa Ana?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Chicago to Santa Ana on time: Emirates (80%), Alaska Airlines (76%), Qatar Airways (74%).

  • What are the cheapest flights from Chicago to Santa Ana?

    The cheapest flight price from Chicago to Santa Ana is $168. On average you can expect to pay $535. The most popular route, (Chicago O'Hare Intl - Santa Ana J. Wayne/Orange Cnty), can usually be booked for $204.

  • Can I find deals for flights from Chicago to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Chicago to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Santa Ana.

  • Can I find deals for business class flights from Chicago to Santa Ana?

    Yes. Cheapflights offers flight deals from Chicago to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Santa Ana?

    Currently, April is the cheapest month in which you can book a flight from Chicago to Santa Ana (average of $67). Flying from Chicago to Santa Ana in March is currently the most expensive (average of $166). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Tustin

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Chicago to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Las Vegas flights
O'Hare Intl to Los Angeles flights
O'Hare Intl to San Francisco flights
O'Hare Intl to San Diego flights
Midway to Las Vegas flights
O'Hare Intl to Ontario flights
O'Hare Intl to Santa Ana flights
Midway to Los Angeles flights
St. Louis to Las Vegas flights
O'Hare Intl to Burbank flights
O'Hare Intl to Palm Springs flights
Midway to San Francisco flights
O'Hare Intl to San Jose flights
O'Hare Intl to Sacramento flights
Rockford to Las Vegas flights
O'Hare Intl to Reno flights
St. Louis to Los Angeles flights
St. Louis to San Francisco flights
Midway to San Diego flights
St. Louis to San Diego flights
O'Hare Intl to Oakland flights
Midway to Palm Springs flights
O'Hare Intl to Fresno flights
Midway to Reno flights
O'Hare Intl to Santa Barbara flights
St. Louis to Ontario flights
Midway to San Jose flights
Midway to Sacramento flights
O'Hare Intl to Long Beach flights
St. Louis to Reno flights
Peoria to Las Vegas flights
Midway to Ontario flights
St. Louis to San Jose flights
Moline to Los Angeles flights
Midway to Oakland flights
Moline to Las Vegas flights
St. Louis to Santa Ana flights
St. Louis to Sacramento flights
O'Hare Intl to Monterey flights
Midway to Long Beach flights
Paducah to Las Vegas flights
Moline to San Diego flights
Bloomington to Las Vegas flights
Evansville to Las Vegas flights
St. Louis to Oakland flights
Midway to Fresno flights
Peoria to Los Angeles flights
Moline to San Francisco flights

Top 7 airlines flying from Chicago to Santa Ana

Discover the top 7 airlines that operate flights from Chicago to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$69Average$165FlexibilityNo cancel feeOn-time65%
FrontierCheapest$129Average$212FlexibilityNo cancel feeOn-time62%
Alaska AirlinesCheapest$248Average$427FlexibilityNo cancel feeOn-time75%
JetBlueCheapest$258Average$352FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$265Average$438FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$269Average$425FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$269Average$360FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.