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$268+ Cheap flights from Panama City (PTY) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/25. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAN
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Panama City to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$361
(United Airlines)

One-way from

$268
(Mytrip)

Popular in

December

Cheapest in

July

Average price

$674

Good round-trip deal

$410 or less
From Panama City Tocumen Intl to San Diego
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One-way flight from Panama City Tocumen Intl to San Diego
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Highest demand for flights based on searches. 8% potential increase in price ($58 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to San Diego.
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Find flight deals from Panama City to San Diego

Cheapest flights from Panama City to San Diego
Explore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/103:35 pmPTY - SAN
1 stop10h 40mUnited Airlines
Tue 10/148:39 pmSAN - PTY
2 stops19h 58mUnited Airlines
Deal found 6/9$361
This Copa Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/101:15 pmPTY - SAN
Nonstop6h 29mCopa Airlines
Fri 8/159:03 pmSAN - PTY
Nonstop6h 22mCopa Airlines
Deal found 6/12$524
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/73:25 amPTY - SAN
2 stops18h 53mMultiple Airlines
Mon 7/219:03 pmSAN - PTY
Nonstop6h 22mMultiple Airlines
Deal found 6/12$681
This Expedia deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/103:40 pmPTY - SAN
2 stops29h 09mAvianca
Mon 12/1510:45 amSAN - PTY
2 stops25h 00mAvianca
Deal found 6/10$1,192

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Panama City to San Diego that are best for you.

Fly from

Panama City

Fly to

San Diego

Route

Depart

Return

Price

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 10/10

3:35 pm-12:15 am

1 stop10h 40m

San Diego

Tue 10/14

8:39 pm-6:37 pm

2 stops19h 58m

$361

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 8/10

1:15 pm-5:44 pm

Nonstop6h 29m

San Diego

Fri 8/15

9:03 pm-5:25 am

Nonstop6h 22m

$524

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Mon 7/7

3:25 am-8:18 pm

2 stops18h 53m

San Diego

Mon 7/21

9:03 pm-5:25 am

Nonstop6h 22m

$681

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 7/8

3:40 pm-10:12 am

2 stops20h 32m

San Diego

Sun 7/20

6:15 am-10:25 am

3 stops26h 10m

$1,394

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Wed 6/25

3:40 pm-7:13 am

3 stops41h 33m

$268

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Wed 9/24

10:00 am-5:59 pm

1 stop9h 59m

$316

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Wed 9/24

1:15 pm-5:50 pm

Nonstop6h 35m

$374

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 10/30

8:05 pm-11:44 pm

3 stops29h 39m

$507

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from Panama City to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Diego

What is the cheapest month to book a flight from Panama City to San Diego?

Currently, August is the cheapest month in which you can book a flight from Panama City to San Diego (average of $286). Flying from Panama City to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SAN?

Find hourly flight availability from Panama City to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

It’s optimal to fly from Panama City to San Diego at noon. By choosing this option you can save up to 77% on the cost of your flight, compared to a flight in the evening.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 12, 2025.
Copa Airlines
7.5
Good
1,451 reviews

Entertainment

6.8

Overall

7.5

Boarding

7.8

Food

6.8

Crew

8.1

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Copa Airlines
7.5
Good
1,451 reviews
Copa Airlines
7.5
Good
1,451 reviews

Entertainment

6.8

Overall

7.5

Boarding

7.8

Food

6.8

Crew

8.1

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
United Airlines
7.4
Good
8,790 reviews
Copa Airlines
7.5
Good
1,451 reviews

Entertainment

6.8

Overall

7.5

Boarding

7.8

Food

6.8

Crew

8.1

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Avianca
6.7
Okay
2,345 reviews
Copa Airlines
7.5
Good
1,451 reviews

Entertainment

6.8

Overall

7.5

Boarding

7.8

Food

6.8

Crew

8.1

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to San Diego round-trip?

    United Airlines, at $361, was found to be the cheapest airline from Panama City to San Diego.Alternate airlines to your destination round-trip include Copa Airlines and Avianca. Users have found that United Airlines is 44% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Panama City to San Diego one-way?

    $316 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Copa Airlines and Avianca, with prices starting from $374 and $507, respectively.

  • What are the cheapest flights from Panama City to San Diego?

    On average you can expect to pay $443 for a flight from Panama City to San Diego. The cheapest flight overall is $224 while the most popular route, (Panama City Tocumen Intl - San Diego) is currently priced at $348.

  • Can I find deals for flights from Panama City to San Diego that include hotel bookings?

    Yes. In addition to deals on Panama City to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Diego.

  • Can I find deals for business class flights from Panama City to San Diego?

    Yes. Cheapflights offers flight deals from Panama City to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Panama City to San Diego (average of $286). Flying from Panama City to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Imperial Beach
La Mesa
Alpine
Lemon Grove
Poway
Santee
Coronado

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama City to San Diego

Discover the top airline that operate flights from Panama City to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$450Average$620FlexibilityNo cancel feeOn-time69%

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