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San Diego

$245+ Cheap flights from Panama to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAN
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Panama to San Diego

Cheapest flights from Panama to San Diego
Explore the most affordable flight options available from Panama to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Copa Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/211:45 pmPTY - SAN
Nonstop6h 52mCopa Airlines
Wed 12/248:12 pmSAN - PTY
Nonstop6h 08mCopa Airlines
Deal found 12/2$429
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:55 amPTY - SAN
1 stop10h 21mUnited Airlines
Fri 12/128:00 pmSAN - PTY
1 stop19h 49mUnited Airlines
Deal found 12/2$497
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:55 amPTY - SAN
1 stop16h 01mUnited Airlines
Wed 12/243:00 pmSAN - PTY
1 stop25h 38mUnited Airlines
Deal found 12/3$505
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:41 pmPTY - SAN
2 stops20h 40mUnited Airlines
Sat 1/311:12 amSAN - PTY
2 stops24h 33mUnited Airlines
Deal found 12/3$532
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/217:50 pmPTY - SAN
3 stops43h 21mMultiple Airlines
Wed 12/248:12 pmSAN - PTY
Nonstop6h 08mMultiple Airlines
Deal found 12/2$585
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/134:41 pmPTY - SAN
2 stops20h 40mUnited Airlines
Sun 12/218:00 amSAN - PTY
1 stop8h 38mUnited Airlines
Deal found 12/3$646
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:55 pmPTY - SAN
3 stops36h 04mMultiple Airlines
Wed 12/248:12 pmSAN - PTY
Nonstop6h 08mMultiple Airlines
Deal found 12/2$670

Find flight deals from Panama to San Diego

Keep the following information in mind while searching for Panama to San Diego flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$434
(United Airlines)

One-way from

$245
(Copa Airlines)

Popular in

February

Cheapest in

October

Average price

$592

Good round-trip deal

$234 or less
Provider with most accurate pricing for Panama City Tocumen Intl-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Diego flights.
Search Deals
From Panama to San Diego
Search Deals
One-way flight from Panama to San Diego
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($107 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Panama to San Diego.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Panama to San Diego that are best for you.

Fly from

Panama

Fly to

San Diego

Route

Depart

Return

Price

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 12/21

1:45 pm-5:37 pm

Nonstop6h 52m

San Diego

Wed 12/24

8:12 pm-5:20 am

Nonstop6h 08m

$429

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 1/16

1:45 pm-5:41 pm

Nonstop6h 56m

San Diego

Fri 1/23

8:16 pm-5:20 am

Nonstop6h 04m

$429

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sat 1/17

4:41 pm-6:36 pm

1 stop28h 55m

San Diego

Sat 1/24

1:51 pm-2:45 pm

1 stop21h 54m

$434

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 1/27

4:41 pm-6:36 pm

1 stop28h 55m

San Diego

Tue 2/3

8:37 pm-2:45 pm

2 stops15h 08m

$483

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Wed 1/28

8:55 am-9:56 pm

1 stop16h 01m

San Diego

Thu 2/5

10:26 am-2:45 pm

1 stop25h 19m

$483

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 1/27

4:41 pm-11:05 am

1 stop21h 24m

San Diego

Wed 2/4

6:00 pm-5:07 pm

2 stops20h 07m

$483

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 1/29

2:27 pm-9:04 am

2 stops21h 37m

San Diego

Tue 2/3

3:12 pm-1:27 pm

2 stops19h 15m

$496

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 1/16

4:41 pm-4:36 pm

1 stop26h 55m

San Diego

Fri 1/23

10:26 am-2:45 pm

1 stop25h 19m

$505

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 12/21

8:55 am-9:56 pm

1 stop16h 01m

San Diego

Wed 12/24

3:00 pm-7:38 pm

1 stop25h 38m

$505

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Mon 12/22

1:45 pm-5:37 pm

Nonstop6h 52m

$245

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 18 results
1
2

Best time to book a flight from Panama to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to San Diego

What is the cheapest month to book a flight from Panama to San Diego?

Currently, January is the cheapest month in which you can book a flight from Panama to San Diego (average of $201). Flying from Panama to San Diego in April is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SAN?

Find hourly flight availability from Panama to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 66% on flights from Panama to San Diego by exploring options for tickets at noon.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated December 4, 2025.
Peruse reviews from past customers who have flown with Copa Airlines and United Airlines from Panama to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,556 reviews

Crew

8.1

Food

6.9

Boarding

7.8

Overall

7.6

Entertainment

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,556 reviews
Copa Airlines
7.6
Good
1,556 reviews

Crew

8.1

Food

6.9

Boarding

7.8

Overall

7.6

Entertainment

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
9,066 reviews
Copa Airlines
7.6
Good
1,556 reviews

Crew

8.1

Food

6.9

Boarding

7.8

Overall

7.6

Entertainment

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Panama to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Panama?

    Most people fly into San Diego (SAN) if they book a flight to San Diego from Panama. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • How long is the flight from Panama to San Diego?

    Airlines like Copa Airlines and United Airlines fly from Panama to San Diego in about 6h 52m. The time it takes to get you to your destination can typically vary by up to 22h 03m. Airlines will cover a distance of 2910 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Panama to San Diego one-way?

    One-way options have recently been found by users for as low as $224 on Copa Airlines. Other airlines that offer cheap prices include United Airlines from $347 and Delta from $362 one-way.

  • What are the cheapest flights from Panama to San Diego?

    Looking at all options, your cheapest flight can be booked for $234. While the most popular route (Panama City Tocumen Intl - San Diego) can be booked for $434 on average, our data indicates $334 when flying from Panama to San Diego.

  • Can I find deals for flights from Panama to San Diego that include hotel bookings?

    Yes. In addition to deals on Panama to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Diego.

  • Can I find deals for business class flights from Panama to San Diego?

    Yes. Cheapflights offers flight deals from Panama to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to San Diego?

    Currently, January is the cheapest month in which you can book a flight from Panama to San Diego (average of $201). Flying from Panama to San Diego in April is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
Julian
National City

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Alternative routes for Panama to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to San Diego

Discover the top 2 airlines that operate flights from Panama to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$224Average$460FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$361Average$600FlexibilityNo cancel feeOn-time69%

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