$132+ Cheap flights from Mississippi to San Diego (SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SAN
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Mississippi to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to San Diego
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Cheapest flights from Mississippi to San DiegoExplore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:54 pm -
1 stop22h 14m
Wed 11/184:53 pm -
1 stop24h 16m
Deal found 9/12![Frontier logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:54 pm -
1 stop22h 14m
Wed 11/184:53 pm -
1 stop24h 16m
Deal found 9/12![Frontier logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:59 pm -
1 stop22h 09m
Thu 10/296:25 am -
1 stop10h 44m
Deal found 9/12![Frontier logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:54 pm -
1 stop22h 14m
Thu 11/196:25 am -
1 stop10h 44m
Deal found 9/12![Frontier logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:35 pm -
1 stop25h 23m
Wed 10/214:53 pm -
1 stop24h 21m
Deal found 9/13![Frontier logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:35 pm -
1 stop25h 23m
Sat 10/244:53 pm -
1 stop24h 21m
Deal found 9/13![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:54 pm -
1 stop22h 14m
Thu 11/196:25 am -
1 stop10h 44m
Deal found 9/12![Frontier logo]()
$253
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:00 am -
1 stop8h 40m
Tue 10/2712:39 pm -
1 stop5h 57m
Deal found 9/14![United Airlines logo]()
$263
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:55 am -
1 stop6h 10m
Tue 10/276:30 am -
1 stop7h 50m
Deal found 9/13![Southwest logo]()
$264
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:42 pm -
1 stop5h 56m
Sat 10/3112:40 pm -
1 stop8h 19m
Deal found 9/15![American Airlines logo]()
$267
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:15 am -
1 stop5h 30m
Sat 10/317:20 am -
2 stops8h 25m
Deal found 9/15![Southwest logo]()
$272
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:52 pm -
1 stop5h 43m
Wed 11/411:08 am -
1 stop7h 42m
Deal found 9/16![American Airlines logo]()
$285
Best flights from Mississippi to San DiegoDiscover carefully curated flight deals from Mississippi to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Mississippi to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:15 am -
1 stop5h 30m
Sat 10/317:20 am -
2 stops8h 25m
Deal found 9/15![Southwest logo]()
$272
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:17 pm -
1 stop8h 21m
Fri 10/163:07 pm -
1 stop6h 39m
Deal found 9/12![American Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:20 am -
1 stop7h 38m
Sat 10/2410:13 am -
1 stop5h 30m
Deal found 9/13![United Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:10 am -
1 stop8h 34m
Mon 10/1910:00 pm -
2 stops11h 16m
Deal found 9/12![Delta logo]()
$354
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:25 am -
2 stops8h 35m
Mon 12/2110:35 pm -
1 stop8h 40m
Deal found 9/15![Southwest logo]()
$305
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:15 pm -
1 stop5h 25m
Wed 11/47:10 am -
1 stop10h 45m
Deal found 9/13![Southwest logo]()
$314
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:45 am -
1 stop7h 55m
Wed 10/216:15 am -
2 stops7h 15m
Deal found 9/15![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:49 pm -
1 stop7h 10m
Tue 12/18:00 am -
1 stop8h 17m
Deal found 9/16![American Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:10 am -
1 stop7h 15m
Mon 10/1210:25 pm -
1 stop8h 08m
Deal found 9/16![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:36 pm -
1 stop9h 39m
Mon 10/269:45 pm -
1 stop9h 47m
Deal found 9/15![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:00 pm -
1 stop5h 40m
Tue 10/278:45 am -
2 stops8h 49m
Deal found 9/15![United Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/105:30 am -
1 stop6h 50m
Sun 2/1412:25 pm -
1 stop6h 50m
Deal found 9/14![Southwest logo]()
$366
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:16 am -
1 stop7h 07m
Fri 11/272:18 pm -
1 stop6h 57m
Deal found 9/11![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:03 am -
1 stop7h 10m
Sun 11/110:25 pm -
1 stop9h 09m
Deal found 9/12![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:23 pm -
1 stop6h 03m
Wed 11/48:45 am -
2 stops11h 14m
Deal found 9/16![United Airlines logo]()
$390
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:59 pm -
1 stop9h 40m
Mon 12/146:15 am -
1 stop7h 02m
Deal found 9/12![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:15 pm -
1 stop6h 33m
Sat 10/36:15 am -
1 stop8h 27m
Deal found 9/14![American Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:14 pm -
1 stop6h 10m
Tue 10/276:20 am -
2 stops11h 14m
Deal found 9/15![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:20 pm -
1 stop5h 35m
Mon 10/1911:40 am -
2 stops8h 15m
Deal found 9/16![Southwest logo]()
$413
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:04 am -
1 stop8h 46m
Mon 10/199:45 pm -
1 stop8h 45m
Deal found 9/12![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:14 pm -
1 stop6h 10m
Sat 10/176:15 am -
2 stops7h 57m
Deal found 9/16![United Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:59 pm -
1 stop7h 20m
Mon 12/710:30 pm -
1 stop8h 02m
Deal found 9/16![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:55 am -
2 stops8h 25m
Sat 10/316:45 am -
1 stop7h 35m
Deal found 9/13![Southwest logo]()
$422
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:44 am -
1 stop6h 41m
Tue 10/64:35 pm -
1 stop5h 24m
Deal found 9/16![American Airlines logo]()
$478
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/173:59 pm -
1 stop9h 40m
Mon 12/219:50 pm -
1 stop8h 45m
Deal found 9/15![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:55 pm -
1 stop6h 31m
Sun 11/86:20 am -
2 stops7h 48m
Deal found 9/16![United Airlines logo]()
$419
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1111:45 am -
1 stop11h 40m
Mon 2/1512:40 pm -
1 stop8h 10m
Deal found 9/14![Southwest logo]()
$440
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:10 am -
1 stop7h 03m
Fri 10/1610:00 pm -
2 stops11h 16m
Deal found 9/12![Delta logo]()
$384
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:45 am -
2 stops13h 00m
Tue 10/610:11 am -
1 stop7h 49m
Deal found 9/17![United Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:40 am -
2 stops7h 40m
Tue 11/39:25 am -
2 stops8h 25m
Deal found 9/12![Southwest logo]()
$441
Last-minute flights from Mississippi to San DiegoDiscover last-minute flight deals from Mississippi to San Diego. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to San Diego. Data last updated September 17, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:35 pm -
1 stop25h 23m
Wed 10/214:53 pm -
1 stop24h 21m
Deal found 9/13![Frontier logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:35 pm -
1 stop25h 23m
Sat 10/244:53 pm -
1 stop24h 21m
Deal found 9/13![Frontier logo]()
$250
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:41 am -
1 stop6h 46m
Tue 10/64:35 pm -
1 stop5h 24m
Deal found 9/15![American Airlines logo]()
$281
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:38 pm -
1 stop7h 58m
Tue 10/2710:25 pm -
1 stop9h 11m
Deal found 9/14![Delta logo]()
$277
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:02 pm -
1 stop7h 00m
Sat 10/176:15 am -
1 stop8h 02m
Deal found 9/14![Delta logo]()
$313
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:00 am -
1 stop8h 40m
Tue 10/2712:39 pm -
1 stop5h 57m
Deal found 9/14![United Airlines logo]()
$263
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:55 am -
1 stop6h 10m
Tue 10/276:30 am -
1 stop7h 50m
Deal found 9/13![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:45 am -
2 stops10h 41m
Sat 10/243:00 pm -
1 stop5h 40m
Deal found 9/16![United Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:59 pm -
1 stop22h 09m
Sun 10/256:25 am -
1 stop10h 49m
Deal found 9/12![Frontier logo]()
$286
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:42 pm -
1 stop5h 56m
Sat 10/3112:40 pm -
1 stop8h 19m
Deal found 9/15![American Airlines logo]()
$267
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:15 am -
1 stop5h 30m
Sat 10/317:20 am -
2 stops8h 25m
Deal found 9/15![Southwest logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:59 pm -
1 stop22h 09m
Thu 10/296:25 am -
1 stop10h 44m
Deal found 9/12![Frontier logo]()
$242
One-way flights from Mississippi to San DiegoSearch for one-way flight options from Mississippi to San Diego. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Mississippi to San Diego. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:41 am -
1 stop6h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$132
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:38 pm -
1 stop7h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$139
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:00 am -
2 stops10h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![United Airlines logo]()
$170
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:15 pm -
1 stop5h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$175
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:00 am -
1 stop8h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$176
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:51 pm -
1 stop7h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$186
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/193:54 pm -
1 stop7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$194
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:00 pm -
1 stop7h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Delta logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:45 pm -
3 stops23h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$195
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:00 am -
2 stops8h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$199
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:14 pm -
2 stops9h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![United Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:01 pm -
1 stop20h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$202
Find flight deals from Mississippi to San Diego
Keep the following information in mind while searching for Mississippi to San Diego flight deals. Data was last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $232 (Kiwi.com) |
One-way from | $132 (American Airlines) |
Popular in | May |
Cheapest in | August |
Average price | $503 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MemphisSan Diego
MEM Memphis - SAN San Diego
MEMSAN
Memphis
Wed 11/25
3:17 pm-9:55 pm
1 stop8h 38m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$132
MemphisSan Diego
MEM Memphis - SAN San Diego
MEMSAN
Memphis
Wed 10/7
1:38 pm-7:36 pm
1 stop7h 58m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$139
MemphisSan Diego
MEM Memphis - SAN San Diego
MEMSAN
Memphis
Sat 10/17
9:00 am-5:05 pm
2 stops10h 05m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$170
Quickest round-trip
JacksonSan Diego
JAN Jackson-Evers Intl - SAN San Diego
JANSAN
Jackson-Evers Intl
Mon 11/2
8:15 pm-11:40 pm
1 stop5h 25m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$175
MemphisSan Diego
MEM Memphis - SAN San Diego
MEMSAN
Memphis
Wed 10/7
9:00 am-3:40 pm
1 stop8h 40m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$176
Baton RougeSan Diego
BTR Baton Rouge Ryan - SAN San Diego
BTRSAN
Baton Rouge Ryan
Thu 11/19
3:54 pm-9:04 pm
1 stop7h 10m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$194
GulfportSan Diego
GPT Gulfport Biloxi Regional - SAN San Diego
GPTSAN
Gulfport Biloxi Regional
Wed 10/14
6:02 pm-11:38 pm
1 stop7h 36m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$194
Baton RougeSan Diego
BTR Baton Rouge Ryan - SAN San Diego
BTRSAN
Baton Rouge Ryan
Thu 11/19
5:00 am-10:59 am
1 stop7h 59m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$194
GulfportSan Diego
GPT Gulfport Biloxi Regional - SAN San Diego
GPTSAN
Gulfport Biloxi Regional
Sat 10/3
4:00 pm-9:19 pm
1 stop7h 19m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$194
Baton RougeSan Diego
BTR Baton Rouge Ryan - SAN San Diego
BTRSAN
Baton Rouge Ryan
Sat 10/3
9:35 am-1:17 pm
1 stop5h 42m
San Diego
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$194
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Mississippi to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Mississippi with our price prediction graph.
MEM-SAN
JAN-SAN
BTR-SAN
GPT-SAN
AEX-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to San Diego
USMS-SAN
MEM-SAN
JAN-SAN
BTR-SAN
GPT-SAN
What is the cheapest month to book a flight from Mississippi to San Diego?
Currently, January is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $295). Flying from Mississippi to San Diego in June is currently the most expensive (average of $701). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Mississippi to San Diego?
Airfare is below average for this route at the moment.
Mississippi to San Diego flights typically cost between $378 and $603 in October.The cheapest round-trip price found within the last 5 days was $267 on American Airlines (Oct 24-Oct 31).
Related info for your journey
Find useful and relevant information for your journey from Mississippi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Coronado
San Ysidro
Poway
La Mesa
Santee
Julian
Lemon Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Mississippi to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Diego by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mississippi to San Diego by cabin class
Find flights from Mississippi to San Diego, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mississippi and San Diego flights
Browse other Mississippi and San Diego flight options. Last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Mississippi to San Diego flights
Consider these flights traveling from Mississippi to San Diego.
Top 4 airlines flying from Mississippi to San Diego
Discover the top 4 airlines that operate flights from Mississippi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$506 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$285 | Average$496 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$331 | Average$548 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$358 | Average$472 | FlexibilityNo cancel fee | On-time63% |