San Diego

$65+ Cheap flights from Mississippi to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SAN
Jul 8 — Jul 151
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Cheap flight deals from Mississippi to San Diego

Keep the following information in mind while searching for Mississippi to San Diego flight deals. Data was last updated July 3, 2025.

Round-trip from

$148
(Priceline)

One-way from

$65
(FlightHub)

Popular in

December

Cheapest in

February

Average price

$446
From Mississippi to San Diego
One-way flight from Mississippi to San Diego
Highest demand for flights based on searches. 6% potential increase in price ($32 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Average for round-trip flights in July 2025

Find flight deals from Mississippi to San Diego

Cheapest flights from Mississippi to San Diego
Explore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Priceline deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/286:20 pmMEM - SAN
1 stop7h 32mFrontier
Mon 9/16:25 amSAN - MEM
1 stop10h 33mFrontier
Deal found 7/1$148
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2810:06 pmMEM - SAN
1 stop13h 49mMultiple Airlines
Tue 7/293:57 pmSAN - MEM
2 stops22h 32mMultiple Airlines
Deal found 7/1$158
This FlightHub deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/113:13 pmMEM - SAN
1 stop10h 32mSpirit Airlines
Tue 9/166:15 amSAN - MEM
1 stop6h 03mSpirit Airlines
Deal found 7/2$167
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/291:52 pmGPT - SAN
1 stop9h 43mDelta
Fri 8/810:30 pmSAN - GPT
1 stop9h 21mDelta
Deal found 7/3$277
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/307:00 amGPT - SAN
1 stop8h 37mAmerican Airlines
Sat 8/96:15 amSAN - GPT
2 stops9h 20mAmerican Airlines
Deal found 7/3$282
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3112:20 pmBTR - SAN
1 stop7h 40mDelta
Thu 8/711:00 amSAN - BTR
1 stop8h 58mDelta
Deal found 7/2$289
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/292:23 pmMOB - SAN
1 stop9h 12mDelta
Sat 8/92:01 pmSAN - MOB
1 stop7h 26mDelta
Deal found 7/3$289
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/304:02 pmBTR - SAN
1 stop7h 10mUnited Airlines
Sat 8/28:46 pmSAN - BTR
2 stops10h 13mUnited Airlines
Deal found 7/1$294
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/3012:37 pmMOB - SAN
1 stop8h 03mAmerican Airlines
Sat 8/99:45 amSAN - MOB
2 stops11h 25mAmerican Airlines
Deal found 7/3$294
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/306:21 pmBTR - SAN
1 stop6h 06mAmerican Airlines
Sat 8/22:27 pmSAN - BTR
1 stop6h 56mAmerican Airlines
Deal found 7/1$308
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/3012:21 pmJAN - SAN
1 stop7h 35mAmerican Airlines
Wed 8/66:15 amSAN - JAN
1 stop7h 06mAmerican Airlines
Deal found 7/2$354
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/178:45 amMEI - SAN
1 stop7h 26mUnited Airlines
Mon 7/2111:58 amSAN - MEI
1 stop6h 07mUnited Airlines
Deal found 7/2$360

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.

Fly from

Mississippi

Fly to

San Diego

Route

Depart

Return

Price

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Thu 8/28

6:20 pm-11:52 pm

1 stop7h 32m

San Diego

Mon 9/1

6:25 am-6:58 pm

1 stop10h 33m

$148

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Mon 7/28

10:06 pm-9:55 am

1 stop13h 49m

San Diego

Tue 7/29

3:57 pm-4:29 pm

2 stops22h 32m

$158

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Thu 9/11

3:13 pm-11:45 pm

1 stop10h 32m

San Diego

Tue 9/16

6:15 am-2:18 pm

1 stop6h 03m

$167

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Tue 7/29

1:52 pm-9:35 pm

1 stop9h 43m

San Diego

Fri 8/8

10:30 pm-9:51 am

1 stop9h 21m

$277

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Wed 7/30

7:00 am-1:37 pm

1 stop8h 37m

San Diego

Sat 8/9

6:15 am-5:35 pm

2 stops9h 20m

$282

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Thu 7/31

12:20 pm-6:00 pm

1 stop7h 40m

San Diego

Thu 8/7

11:00 am-9:58 pm

1 stop8h 58m

$289

MobileSan Diego

MOB - SAN

MOBSAN

Mobile

Tue 7/29

12:46 pm-6:00 pm

1 stop7h 14m

San Diego

Fri 8/8

10:30 pm-8:36 am

1 stop8h 06m

$289

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Wed 7/30

4:02 pm-9:12 pm

1 stop7h 10m

San Diego

Sat 8/2

8:46 pm-8:59 am

2 stops10h 13m

$294

MobileSan Diego

MOB - SAN

MOBSAN

Mobile

Wed 7/30

12:37 pm-8:20 pm

1 stop9h 43m

San Diego

Sat 8/9

12:50 pm-11:10 pm

2 stops8h 20m

$294

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Wed 7/30

6:21 pm-10:27 pm

1 stop6h 06m

San Diego

Sat 8/2

2:27 pm-11:23 pm

1 stop6h 56m

$308

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 35 results
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Best time to book a flight from Mississippi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to San Diego

What is the cheapest month to book a flight from Mississippi to San Diego?

Currently, August is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $286). Flying from Mississippi to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SAN?

Find hourly flight availability from Mississippi to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to San Diego as you normally would.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with Breeze Airways, Southwest, and Delta from Mississippi to San Diego to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.2

Food

6.8

Overall

8.1

Crew

8.8

Entertainment

6.6

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Comfort

8.2

Food

6.8

Overall

8.1

Crew

8.8

Entertainment

6.6

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Comfort

8.2

Food

6.8

Overall

8.1

Crew

8.8

Entertainment

6.6

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
8.0
Very good

Comfort

8.2

Food

6.8

Overall

8.1

Crew

8.8

Entertainment

6.6

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Comfort

8.2

Food

6.8

Overall

8.1

Crew

8.8

Entertainment

6.6

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Comfort

8.2

Food

6.8

Overall

8.1

Crew

8.8

Entertainment

6.6

Boarding

8.3

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Mississippi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Diego from Mississippi?

    For a flight from Mississippi to San Diego, you will be flying into San Diego. San Diego (SAN) is just 2.6 mi from the center of the city.

  • What are the cheapest airlines to fly from Mississippi to San Diego one-way?

    One-way options have recently been found by users for as low as $65 on Spirit Airlines. Other airlines that offer cheap prices include Frontier from $79 and American Airlines from $144 one-way.

  • What are the most popular routes from Mississippi to San Diego?

  • Can I find deals for flights from Mississippi to San Diego that include hotel bookings?

    Yes. In addition to deals on Mississippi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to San Diego.

  • Can I find deals for business class flights from Mississippi to San Diego?

    Yes. Cheapflights offers flight deals from Mississippi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $286). Flying from Mississippi to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mississippi?

Book flights to Mississippi if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
National City
Lemon Grove
Imperial Beach
La Mesa
Poway
Alpine
Santee

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to San Diego

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Mississippi to San Diego

Discover the top 4 airlines that operate flights from Mississippi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$276Average$441FlexibilityNo cancel feeOn-time71%
DeltaCheapest$286Average$403FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$297Average$451FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$362Average$486FlexibilityNo cancel feeOn-time63%

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