San Diego

$70+ Cheap flights from Mississippi to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SAN
may. 4 — may. 111
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Cheap flight deals from Mississippi to San Diego

Cheapest flights from Mississippi to San Diego
Explore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 4, 2026.

This Expedia deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/117:54 pm
MEM
-
SAN
1 stop5h 56m
Frontier
lun. 5/186:25 am
SAN
-
MEM
1 stop10h 44m
Frontier
Deal found 4/1$160
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/279:17 pm
MEM
-
SAN
1 stop18h 00m
Multiple Airlines
sáb. 5/96:25 am
SAN
-
MEM
2 stops26h 34m
Multiple Airlines
Deal found 3/31$181
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/279:17 pm
MEM
-
SAN
1 stop18h 00m
Multiple Airlines
vie. 5/86:25 am
SAN
-
MEM
1 stop10h 44m
Multiple Airlines
Deal found 3/31$184
This Booking.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/267:57 pm
MEM
-
SAN
1 stop14h 37m
Frontier
mié. 4/2910:30 am
SAN
-
MEM
1 stop27h 11m
Frontier
Deal found 3/30$198
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/279:17 pm
MEM
-
SAN
1 stop18h 00m
Multiple Airlines
mié. 5/136:25 am
SAN
-
MEM
2 stops33h 30m
Multiple Airlines
Deal found 3/31$199
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/107:51 pm
MEM
-
SAN
2 stops14h 51m
Frontier
lun. 5/186:25 am
SAN
-
MEM
1 stop10h 44m
Frontier
Deal found 4/1$203
This Expedia deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/117:54 pm
MEM
-
SAN
1 stop5h 56m
Frontier
vie. 5/156:25 am
SAN
-
MEM
1 stop10h 44m
Frontier
Deal found 4/1$205
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/279:17 pm
MEM
-
SAN
1 stop18h 00m
Multiple Airlines
dom. 5/101:38 pm
SAN
-
MEM
2 stops27h 31m
Multiple Airlines
Deal found 4/1$206
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/279:17 pm
MEM
-
SAN
1 stop18h 00m
Multiple Airlines
lun. 5/116:25 am
SAN
-
MEM
1 stop10h 44m
Multiple Airlines
Deal found 3/31$207
This Frontier deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/87:54 pm
MEM
-
SAN
1 stop5h 56m
Frontier
lun. 5/186:25 am
SAN
-
MEM
1 stop10h 44m
Frontier
Deal found 4/1$210
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/157:37 pm
GPT
-
SAN
1 stop6h 19m
American Airlines
sáb. 4/181:36 pm
SAN
-
GPT
1 stop8h 22m
American Airlines
Deal found 4/1$257
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/155:15 pm
GPT
-
SAN
1 stop6h 11m
United Airlines
sáb. 4/186:32 am
SAN
-
GPT
2 stops11h 21m
United Airlines
Deal found 4/1$262

Find flight deals from Mississippi to San Diego

Keep the following information in mind while searching for Mississippi to San Diego flight deals. Data was last updated abril 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$160
(Expedia)

One-way from

$70
(Kiwi.com)

Popular in

June

Cheapest in

August

Average price

$524
Provider with most accurate pricing for Jackson-Evers Intl-San Diego flight deals.
Provider most trusted by Cheapflights users for Jackson-Evers Intl-San Diego flights.
From Mississippi to San Diego
One-way flight from Mississippi to San Diego
Highest demand for flights based on searches. 14% potential increase in price ($88 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($24 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 4, 2026.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

mié. 4/22

5:55 pm-11:25 pm

1 stop7h 30m

San Diego

lun. 4/27

10:30 pm-9:24 am

1 stop8h 54m

$277

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

vie. 5/22

7:54 pm-11:50 pm

1 stop5h 56m

San Diego

lun. 5/25

6:25 am-7:09 pm

1 stop10h 44m

$290

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

mié. 4/29

4:08 pm-8:05 pm

1 stop5h 57m

San Diego

vie. 5/1

3:04 pm-10:46 pm

1 stop5h 42m

$297

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

mié. 5/27

1:37 pm-7:23 pm

1 stop7h 46m

San Diego

mar. 6/2

10:25 pm-9:45 am

1 stop9h 20m

$297

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

sáb. 8/15

2:00 pm-5:46 pm

1 stop5h 46m

San Diego

sáb. 8/22

8:45 am-9:13 pm

2 stops10h 28m

$302

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

jue. 4/30

12:00 pm-5:53 pm

1 stop7h 53m

San Diego

jue. 5/7

3:04 pm-10:46 pm

1 stop5h 42m

$321

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

lun. 4/27

9:20 am-5:16 pm

2 stops9h 56m

San Diego

mié. 4/29

3:04 pm-10:45 pm

1 stop5h 41m

$325

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

mié. 4/29

2:05 pm-6:05 pm

1 stop6h 00m

San Diego

sáb. 5/2

10:23 am-7:53 pm

1 stop7h 30m

$357

MobileSan Diego

MOB - SAN

MOBSAN

Mobile

mié. 4/22

4:04 pm-11:25 pm

1 stop9h 21m

San Diego

dom. 4/26

9:45 pm-8:32 am

1 stop8h 47m

$369

MeridianSan Diego

MEI - SAN

MEISAN

Meridian Key Field

vie. 4/24

1:45 pm-11:59 pm

2 stops12h 14m

San Diego

lun. 4/27

6:20 am-6:37 pm

2 stops10h 17m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Mississippi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to San Diego

What is the cheapest month to book a flight from Mississippi to San Diego?

Currently, February is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $165). Flying from Mississippi to San Diego in April is currently the most expensive (average of $400). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Mississippi to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Mississippi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Diego from Mississippi?

    For a flight from Mississippi to San Diego, you will be flying into San Diego. San Diego (SAN) is just 2.6 mi from the center of the city.

  • How long is the flight from Mississippi to San Diego?

    Delta, Frontier, and United Airlines can get you from Mississippi to San Diego in just under 5h 56m. Your travel time can differ by up to 1h 34m. Mississippi and San Diego are separated by a distance of 1563 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to San Diego one-way?

    One-way options have recently been found by users for as low as $138 on Delta. Other airlines that offer cheap prices include American Airlines from $138 and United Airlines from $175 one-way.

  • What are the most popular routes from Mississippi to San Diego?

  • Can I find deals for flights from Mississippi to San Diego that include hotel bookings?

    Yes. In addition to deals on Mississippi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to San Diego.

  • Can I find deals for business class flights from Mississippi to San Diego?

    Yes. Cheapflights offers flight deals from Mississippi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to San Diego?

    Currently, February is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $165). Flying from Mississippi to San Diego in April is currently the most expensive (average of $400). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to San Diego

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Mississippi to San Diego

Discover the top 4 airlines that operate flights from Mississippi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$138Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$453FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$271Average$477FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$358Average$532FlexibilityNo cancel feeOn-time63%

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