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$38+ Cheap flights from Mesa, AZ to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SAN
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to San Diego are usually found in February or November, booked 80 days in advance, depart on a Friday or Thursday and return on a Friday

Find flight deals from Mesa to San Diego

Cheapest flights from Mesa to San Diego
Explore the most affordable flight options available from Mesa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/267:25 amPHX - SAN
Nonstop1h 19mFrontier
Sat 11/298:39 amSAN - PHX
Nonstop1h 31mFrontier
Deal found 10/29$68
This Priceline deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/188:00 pmPHX - SAN
Nonstop1h 24mFrontier
Fri 11/218:39 amSAN - PHX
Nonstop1h 31mFrontier
Deal found 10/30$70
This Trip.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/237:30 amPHX - SAN
Nonstop1h 19mFrontier
Sat 11/298:39 amSAN - PHX
Nonstop1h 31mFrontier
Deal found 10/27$71
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:30 amPHX - SAN
Nonstop1h 17mFrontier
Sat 12/279:32 amSAN - PHX
Nonstop1h 32mFrontier
Deal found 10/29$72
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:02 amPHX - SAN
Nonstop1h 28mMultiple Airlines
Mon 12/83:05 pmSAN - PHX
Nonstop1h 27mMultiple Airlines
Deal found 10/28$73
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/128:00 pmPHX - SAN
Nonstop1h 24mFrontier
Sat 11/158:00 amSAN - PHX
Nonstop1h 28mFrontier
Deal found 10/30$74
This Frontier deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:03 pmPHX - SAN
1 stop6h 48mFrontier
Mon 12/83:05 pmSAN - PHX
Nonstop1h 27mFrontier
Deal found 10/28$75
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2912:58 pmPHX - SAN
Nonstop1h 17mFrontier
Mon 1/52:10 pmSAN - PHX
Nonstop1h 29mFrontier
Deal found 10/29$77
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/257:25 amPHX - SAN
Nonstop1h 19mFrontier
Wed 11/268:29 amSAN - PHX
Nonstop1h 31mFrontier
Deal found 10/29$78
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/158:00 pmPHX - SAN
Nonstop1h 24mFrontier
Mon 11/1711:34 amSAN - PHX
Nonstop1h 39mFrontier
Deal found 10/29$81
This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:00 amPHX - SAN
Nonstop1h 24mFrontier
Mon 11/1711:34 amSAN - PHX
Nonstop1h 39mFrontier
Deal found 10/29$82

Cheap flight deals from Mesa to San Diego

Keep the following information in mind while searching for Mesa to San Diego flight deals. Data was last updated October 30, 2025.

Most accurate provider

Expedia
2 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$68
(Frontier)

One-way from

$38
(Kiwi.com)

Popular in

April

Cheapest in

February

Average price

$127
Provider with most accurate pricing for Phoenix-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Phoenix-San Diego flights.
Search Deals
From Mesa to San Diego
Search Deals
One-way flight from Mesa to San Diego
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Mesa to San Diego that are best for you.

Fly from

Mesa

Fly to

San Diego

Route

Depart

Return

Price

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Tue 1/27

3:45 pm-4:02 pm

Nonstop1h 17m

San Diego

Tue 2/10

5:00 pm-7:25 pm

Nonstop1h 25m

$97

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Thu 12/4

6:02 am-6:30 am

Nonstop1h 28m

San Diego

Mon 12/8

12:41 pm-3:13 pm

Nonstop1h 32m

$97

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Wed 2/18

6:00 pm-8:50 pm

1 stop3h 50m

San Diego

Sat 2/21

7:25 pm-9:55 pm

Nonstop1h 30m

$107

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Tue 1/6

1:10 pm-5:15 pm

1 stop5h 05m

San Diego

Thu 1/8

6:50 am-9:10 am

Nonstop1h 20m

$107

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Tue 1/27

3:45 pm-4:02 pm

Nonstop1h 17m

San Diego

Sun 2/8

5:00 pm-7:25 pm

Nonstop1h 25m

$107

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Mon 1/26

11:41 am-12:00 pm

Nonstop1h 19m

San Diego

Sat 2/7

11:35 am-2:00 pm

Nonstop1h 25m

$107

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Thu 11/20

6:50 pm-7:12 pm

Nonstop1h 22m

San Diego

Sun 11/23

9:17 pm-11:40 pm

Nonstop1h 23m

$109

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Wed 11/12

5:16 pm-9:39 pm

1 stop5h 23m

San Diego

Sat 11/15

6:41 am-5:06 pm

1 stop9h 25m

$110

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Tue 11/25

6:02 am-6:30 am

Nonstop1h 28m

San Diego

Tue 12/2

12:41 pm-3:13 pm

Nonstop1h 32m

$117

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Sat 2/28

11:40 am-11:55 am

Nonstop1h 15m

San Diego

Mon 3/9

1:55 pm-3:17 pm

Nonstop1h 22m

$117

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 23 results
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Best time to book a flight from Mesa to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to San Diego

How far ahead should I book a flight from Mesa to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to San Diego. Price data was last updated on October 24, 2025.

Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to San Diego?

Currently, February is the cheapest month in which you can book a flight from Mesa to San Diego (average of $38). Flying from Mesa to San Diego in June is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SAN?

Find hourly flight availability from Mesa to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 54% on flights from Mesa to San Diego by exploring options for tickets at noon.

What is the cheapest day to fly from Mesa to San Diego?

Use this chart to determine the cheapest time to fly round-trip from Mesa to San Diego. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to San Diego flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest, and Hawaiian Airlines from Mesa to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,214 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
11,214 reviews
Alaska Airlines
8.0
Very good
11,214 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Southwest
8.0
Very good
4,242 reviews
Alaska Airlines
8.0
Very good
11,214 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Hawaiian Airlines
7.8
Good
2,797 reviews
Alaska Airlines
8.0
Very good
11,214 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
11,030 reviews
Alaska Airlines
8.0
Very good
11,214 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,123 reviews
Alaska Airlines
8.0
Very good
11,214 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Mesa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Mesa?

    Located just 2.6 mi from the city center, San Diego is the airport most travelers will use when flying to San Diego from Mesa. Booking flights from Mesa to San Diego (SAN) should be relatively easy as there are 8 daily inbound flights from Mesa from 7 different airlines.

  • How long is the flight from Mesa to San Diego?

    Alaska Airlines and Southwest can get you from Mesa to San Diego in just under 1h 17m. Your travel time can differ by up to 2h 33m. The distance between Mesa and San Diego is about 305 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most reliable airlines from Mesa to San Diego?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Mesa to San Diego on time: Alaska Airlines (89%), Hawaiian Airlines (86%), Japan Airlines (82%).

  • What are the cheapest flights from Mesa to San Diego?

    While on average a flight from Mesa to San Diego is generally $640, our data shows the cheapest flight currently is $34. When looking at the most popular route, (Phoenix Sky Harbor Intl - San Diego), you can expect to pay $57 for that flight.

  • Can I find deals for flights from Mesa to San Diego that include hotel bookings?

    Yes. In addition to deals on Mesa to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to San Diego.

  • Can I find deals for business class flights from Mesa to San Diego?

    Yes. Cheapflights offers flight deals from Mesa to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to San Diego?

    Currently, February is the cheapest month in which you can book a flight from Mesa to San Diego (average of $38). Flying from Mesa to San Diego in June is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
National City

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Top 7 airlines flying from Mesa to San Diego

Discover the top 7 airlines that operate flights from Mesa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$47Average$133FlexibilityNo cancel feeOn-time65%
FrontierCheapest$54Average$148FlexibilityNo cancel feeOn-time62%
Hawaiian AirlinesCheapest$58Average$147FlexibilityNo cancel feeOn-time85%
Alaska AirlinesCheapest$77Average$123FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$96Average$220FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$97Average$241FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$269Average$404FlexibilityNo cancel feeOn-time69%

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