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$43+ Cheap flights from Mesa, AZ to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SAN
Apr 26 — May 31
Sun 4/26
Sun 5/3
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to San Diego are usually found in October or September, booked 71 days in advance, depart on a Friday or Thursday and return on a Friday

Cheap flight deals from Mesa to San Diego

Cheapest flights from Mesa to San Diego
Explore the most affordable flight options available from Mesa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.

This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:26 am
PHX
-
SAN
Nonstop1h 17m
Frontier
Mon 6/11:38 pm
SAN
-
PHX
Nonstop1h 34m
Frontier
Deal found 3/25$54
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:10 am
PHX
-
SAN
Nonstop1h 24m
Frontier
Wed 4/1512:29 pm
SAN
-
PHX
Nonstop1h 31m
Frontier
Deal found 3/25$55
This Trip.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:03 pm
PHX
-
SAN
Nonstop1h 25m
Frontier
Mon 4/206:43 pm
SAN
-
PHX
Nonstop1h 29m
Frontier
Deal found 3/23$56
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:26 am
PHX
-
SAN
Nonstop1h 17m
Frontier
Sat 5/166:54 pm
SAN
-
PHX
Nonstop1h 26m
Frontier
Deal found 3/26$65
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:42 am
PHX
-
SAN
Nonstop1h 24m
Frontier
Mon 5/48:38 am
SAN
-
PHX
Nonstop1h 33m
Frontier
Deal found 3/25$66
This Expedia deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
PHX
-
SAN
Nonstop1h 21m
Frontier
Thu 4/167:23 pm
SAN
-
PHX
Nonstop1h 32m
Frontier
Deal found 3/23$67
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:26 am
PHX
-
SAN
Nonstop1h 17m
Frontier
Mon 6/11:38 pm
SAN
-
PHX
Nonstop1h 34m
Frontier
Deal found 3/23$68
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/194:43 pm
PHX
-
SAN
Nonstop1h 18m
Frontier
Tue 4/2112:29 pm
SAN
-
PHX
Nonstop1h 31m
Frontier
Deal found 3/25$71
This Super.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:30 pm
PHX
-
SAN
Nonstop1h 18m
Frontier
Sun 4/266:56 pm
SAN
-
PHX
Nonstop1h 29m
Frontier
Deal found 3/22$74
This Priceline deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:08 pm
PHX
-
SAN
Nonstop1h 16m
Frontier
Sun 5/36:56 pm
SAN
-
PHX
Nonstop1h 29m
Frontier
Deal found 3/26$75
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:15 pm
PHX
-
SAN
Nonstop1h 16m
Frontier
Wed 5/274:17 pm
SAN
-
PHX
Nonstop1h 26m
Frontier
Deal found 3/23$76

Find flight deals from Mesa to San Diego

Keep the following information in mind while searching for Mesa to San Diego flight deals. Data was last updated March 27, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$54
(Frontier)

One-way from

$43
(Frontier)

Popular in

March

Cheapest in

October

Average price

$174
Provider with most accurate pricing for Phoenix-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Phoenix-San Diego flights.
Search Deals
From Mesa to San Diego
Search Deals
One-way flight from Mesa to San Diego
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($15 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Mesa to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Thu 4/16

11:00 am-12:10 pm

Nonstop1h 10m

San Diego

Sun 4/19

6:20 am-7:50 am

Nonstop1h 30m

$137

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Fri 4/24

9:55 pm-11:05 pm

Nonstop1h 10m

San Diego

Fri 5/1

4:30 pm-8:50 pm

1 stop4h 20m

$147

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Sun 4/19

6:40 am-7:55 am

Nonstop1h 15m

San Diego

Wed 4/22

7:25 am-11:20 am

1 stop3h 55m

$147

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Sun 4/19

6:40 am-7:55 am

Nonstop1h 15m

San Diego

Sun 4/19

8:30 pm-12:05 am

1 stop3h 35m

$147

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Mon 4/20

4:50 pm-6:00 pm

Nonstop1h 10m

San Diego

Mon 4/27

6:50 pm-10:10 pm

1 stop3h 20m

$147

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Sat 4/25

3:42 pm-10:38 pm

1 stop6h 56m

San Diego

Sun 4/26

6:20 am-9:54 am

1 stop3h 34m

$152

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Wed 5/13

7:55 pm-11:15 pm

1 stop3h 20m

San Diego

Sat 5/16

6:15 am-11:25 am

1 stop5h 10m

$157

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Thu 4/23

6:00 am-10:20 am

1 stop4h 20m

San Diego

Sun 5/3

6:05 pm-9:32 pm

1 stop3h 27m

$157

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Fri 5/1

4:40 pm-10:36 pm

1 stop5h 56m

San Diego

Mon 5/4

7:45 pm-11:14 pm

1 stop3h 29m

$157

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Thu 4/16

9:25 am-1:00 pm

1 stop3h 35m

San Diego

Fri 4/17

6:50 pm-11:10 pm

1 stop4h 20m

$157

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/22

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from Mesa to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to San Diego

How far ahead should I book a flight from Mesa to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to San Diego. Price data was last updated on March 13, 2026.

Booking 71 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to San Diego?

Currently, February is the cheapest month in which you can book a flight from Mesa to San Diego (average of $38). Flying from Mesa to San Diego in June is currently the most expensive (average of $87). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SAN?

Find hourly flight availability from Mesa to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 27, 2026.

Unlike in the evening, when flights are generally more expensive, you can save up to 25% on flights from Mesa to San Diego by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Mesa to San Diego?

Use this chart to determine the cheapest time to fly round-trip from Mesa to San Diego. Price data was last updated on March 23, 2026.

Travelers seeking maximum savings on their Mesa to San Diego flight should consider departing on Friday afternoons when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Mesa to San Diego

Explore weekly flight availability from Mesa to San Diego. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 27, 2026.

The most flights from MS9 to SAN are scheduled on a Wednesday (30 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (13 on average).

How much does it cost to fly round-trip from Mesa to San Diego?

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 27, 2026.
Peruse reviews from past customers who have flown with Southwest,Alaska Airlines, andHawaiian Airlines from Mesa to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,331 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,331 reviews
Southwest
8.0
Very good
4,331 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Alaska Airlines
7.9
Good
12,120 reviews
Southwest
8.0
Very good
4,331 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Hawaiian Airlines
7.8
Good
2,839 reviews
Southwest
8.0
Very good
4,331 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,507 reviews
Southwest
8.0
Very good
4,331 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Frontier
5.7
Fair
3,014 reviews
Southwest
8.0
Very good
4,331 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Mesa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Mesa?

    Located just 2.6 mi from the city center, San Diego is the airport most travelers will use when flying to San Diego from Mesa. Booking flights from Mesa to San Diego (SAN) should be relatively easy as there are 23 daily inbound flights from Mesa from 6 different airlines.

  • How long is the flight from Mesa to San Diego?

    Southwest can get you from Mesa to San Diego in just under 1h 10m. Your travel time will be generally consistent. The distance between Mesa and San Diego is about 305 mi. Generally, flights for this route are nonstop.

  • What are the cheapest airlines to fly from Mesa to San Diego one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $29. However, be on the lookout for offers from Hawaiian Airlines and Alaska Airlines, as they are both options that can get you from Mesa to San Diego for a low price.

  • What are the most reliable airlines from Mesa to San Diego?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Mesa to San Diego on time: Japan Airlines (89%), Porter Airlines (86%), Frontier (84%).

  • What are the cheapest flights from Mesa to San Diego?

    While on average a flight from Mesa to San Diego is generally $310, our data shows the cheapest flight currently is $45. When looking at the most popular route, (Phoenix Sky Harbor Intl - San Diego), you can expect to pay $87 for that flight.

  • Can I find deals for flights from Mesa to San Diego that include hotel bookings?

    Yes. In addition to deals on Mesa to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to San Diego.

  • Can I find deals for business class flights from Mesa to San Diego?

    Yes. Cheapflights offers flight deals from Mesa to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to San Diego?

    Currently, February is the cheapest month in which you can book a flight from Mesa to San Diego (average of $38). Flying from Mesa to San Diego in June is currently the most expensive (average of $87). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mesa to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Mesa to San Diego

Discover the top 6 airlines that operate flights from Mesa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$41Average$144FlexibilityNo cancel feeOn-time62%
Hawaiian AirlinesCheapest$48Average$139FlexibilityNo cancel feeOn-time85%
Alaska AirlinesCheapest$79Average$154FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$87Average$194FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$97Average$227FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$273Average$381FlexibilityNo cancel feeOn-time69%

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