HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Diego

$30+ Cheap flights from Mesa, AZ to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SAN
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mesa to San Diego with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Mesa to San Diego are usually found in October or February, booked 80 days in advance, depart on a Friday or Thursday and return on a Friday

Cheap flight deals from Mesa to San Diego

Cheapest flights from Mesa to San Diego
Explore the most affordable flight options available from Mesa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:36 amPHX - SAN
Nonstop1h 21mFrontier
Wed 1/71:03 pmSAN - PHX
Nonstop1h 35mFrontier
Deal found 12/15$67
This Super.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:36 amPHX - SAN
Nonstop1h 21mFrontier
Thu 12/259:14 pmSAN - PHX
Nonstop1h 26mFrontier
Deal found 12/17$77
This Frontier deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:36 amPHX - SAN
Nonstop1h 21mFrontier
Thu 1/19:14 pmSAN - PHX
Nonstop1h 26mFrontier
Deal found 12/17$78
This Frontier deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:58 pmPHX - SAN
Nonstop1h 17mFrontier
Wed 12/2410:57 amSAN - PHX
Nonstop1h 33mFrontier
Deal found 12/15$79
This Booking.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:36 amPHX - SAN
Nonstop1h 21mFrontier
Mon 12/292:10 pmSAN - PHX
Nonstop1h 29mFrontier
Deal found 12/16$80
This eDestinos deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:36 amPHX - SAN
Nonstop1h 21mFrontier
Wed 12/2410:57 amSAN - PHX
Nonstop1h 33mFrontier
Deal found 12/16$89
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:36 amPHX - SAN
Nonstop1h 21mFrontier
Thu 1/19:14 pmSAN - PHX
Nonstop1h 26mFrontier
Deal found 12/17$93
This Frontier deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:36 amPHX - SAN
Nonstop1h 21mFrontier
Mon 12/292:10 pmSAN - PHX
Nonstop1h 29mFrontier
Deal found 12/18$94
This Super.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:36 amPHX - SAN
Nonstop1h 21mFrontier
Sat 1/39:32 amSAN - PHX
Nonstop1h 32mFrontier
Deal found 12/17$103
This Frontier deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:36 amPHX - SAN
Nonstop1h 21mFrontier
Sun 1/48:59 pmSAN - PHX
Nonstop1h 29mFrontier
Deal found 12/17$104

Find flight deals from Mesa to San Diego

Keep the following information in mind while searching for Mesa to San Diego flight deals. Data was last updated December 18, 2025.

Most accurate provider

Expedia
2 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$61
(Kiwi.com)

One-way from

$30
(Mytrip)

Popular in

April

Cheapest in

October

Average price

$157
Provider with most accurate pricing for Phoenix-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Phoenix-San Diego flights.
Search Deals
From Mesa to San Diego
Search Deals
One-way flight from Mesa to San Diego
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($3 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Mesa to San Diego that are best for you.

Fly from

Mesa

Fly to

San Diego

Route

Depart

Return

Price

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Sat 1/10

1:33 pm-1:51 pm

Nonstop1h 18m

San Diego

Mon 1/12

1:04 pm-9:30 pm

1 stop7h 26m

$85

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Fri 1/9

8:30 am-3:52 pm

1 stop8h 22m

San Diego

Sun 1/11

9:19 pm-11:44 pm

Nonstop1h 25m

$94

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Wed 2/18

12:28 pm-12:45 pm

Nonstop1h 17m

San Diego

Wed 2/18

9:21 pm-11:42 pm

Nonstop1h 21m

$117

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Wed 2/18

8:55 am-9:15 am

Nonstop1h 20m

San Diego

Wed 2/18

5:40 pm-8:00 pm

Nonstop1h 20m

$117

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Wed 3/4

12:28 pm-12:45 pm

Nonstop1h 17m

San Diego

Wed 3/4

9:21 pm-11:42 pm

Nonstop1h 21m

$117

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Wed 1/7

8:35 pm-8:50 pm

Nonstop1h 15m

San Diego

Sat 1/10

11:40 am-2:05 pm

Nonstop1h 25m

$117

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Sat 2/7

3:45 pm-4:02 pm

Nonstop1h 17m

San Diego

Mon 2/9

5:00 pm-7:25 pm

Nonstop1h 25m

$127

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Tue 1/13

2:30 pm-2:45 pm

Nonstop1h 15m

San Diego

Tue 1/20

12:30 pm-5:45 pm

1 stop4h 15m

$127

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Wed 1/14

5:10 pm-11:07 pm

1 stop6h 57m

$57

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Sat 2/21

8:20 am-8:40 am

Nonstop1h 20m

$59

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 15 results
1
2

Best time to book a flight from Mesa to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to San Diego

How far ahead should I book a flight from Mesa to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to San Diego. Price data was last updated on December 12, 2025.

Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to San Diego?

Currently, February is the cheapest month in which you can book a flight from Mesa to San Diego (average of $38). Flying from Mesa to San Diego in June is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SAN?

Find hourly flight availability from Mesa to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 51% on flights from Mesa to San Diego by exploring options for tickets at noon.

What is the cheapest day to fly from Mesa to San Diego?

Use this chart to determine the cheapest time to fly round-trip from Mesa to San Diego. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to San Diego flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Mesa to San Diego

Explore weekly flight availability from Mesa to San Diego. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 18, 2025.

The most flights from MS9 to SAN are scheduled on a Thursday (32 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (11 on average).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated December 18, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest, and Hawaiian Airlines from Mesa to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,478 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
11,478 reviews
Alaska Airlines
8.0
Very good
11,478 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Southwest
7.9
Good
4,250 reviews
Alaska Airlines
8.0
Very good
11,478 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Hawaiian Airlines
7.8
Good
2,820 reviews
Alaska Airlines
8.0
Very good
11,478 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
11,055 reviews
Alaska Airlines
8.0
Very good
11,478 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,081 reviews
Alaska Airlines
8.0
Very good
11,478 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Mesa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Mesa?

    Located just 2.6 mi from the city center, San Diego is the airport most travelers will use when flying to San Diego from Mesa. Booking flights from Mesa to San Diego (SAN) should be relatively easy as there are 17 daily inbound flights from Mesa from 7 different airlines.

  • How long is the flight from Mesa to San Diego?

    Frontier, Alaska Airlines, and Southwest can get you from Mesa to San Diego in just under 1h 17m. Your travel time will be generally consistent. The distance between Mesa and San Diego is about 305 mi. Generally, flights for this route are nonstop.

  • What are the cheapest airlines to fly from Mesa to San Diego one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $28. However, be on the lookout for offers from Hawaiian Airlines and Alaska Airlines, as they are both options that can get you from Mesa to San Diego for a low price.

  • What are the most reliable airlines from Mesa to San Diego?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Mesa to San Diego on time: Japan Airlines (86%), Southwest (74%), Horizon Air (73%).

  • What are the cheapest flights from Mesa to San Diego?

    While on average a flight from Mesa to San Diego is generally $338, our data shows the cheapest flight currently is $29. When looking at the most popular route, (Phoenix Sky Harbor Intl - San Diego), you can expect to pay $61 for that flight.

  • Can I find deals for flights from Mesa to San Diego that include hotel bookings?

    Yes. In addition to deals on Mesa to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to San Diego.

  • Can I find deals for business class flights from Mesa to San Diego?

    Yes. Cheapflights offers flight deals from Mesa to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to San Diego?

    Currently, February is the cheapest month in which you can book a flight from Mesa to San Diego (average of $38). Flying from Mesa to San Diego in June is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
National City
La Mesa
Poway
Julian
Lemon Grove

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mesa to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
Sky Harbor Intl to Las Vegas flights
Sky Harbor Intl to Los Angeles flights
Las Vegas to Los Angeles flights
Sky Harbor Intl to San Francisco flights
Las Vegas to Burbank flights
Sky Harbor Intl to Ontario flights
Las Vegas to Santa Ana flights
Las Vegas to San Francisco flights
Sky Harbor Intl to San Diego flights
Tucson to Las Vegas flights
Sky Harbor Intl to San Jose flights
Sky Harbor Intl to Santa Ana flights
Las Vegas to San Diego flights
Sky Harbor Intl to Sacramento flights
Sky Harbor Intl to Burbank flights
Las Vegas to Ontario flights
Las Vegas to San Jose flights
Phoenix-Mesa Gateway to Las Vegas flights
Las Vegas to Oakland flights
Las Vegas to Fresno flights
Tucson to Los Angeles flights
Las Vegas to Sacramento flights
Las Vegas to Reno flights
Sky Harbor Intl to Reno flights
Tucson to San Francisco flights
Tucson to San Diego flights
Sky Harbor Intl to Monterey flights
Sky Harbor Intl to Fresno flights
Sky Harbor Intl to San Luis Obispo flights
Sky Harbor Intl to Oakland flights
Las Vegas to Stockton flights
Sky Harbor Intl to Palm Springs flights
Sky Harbor Intl to Long Beach flights
Tucson to Ontario flights
Tucson to Santa Ana flights
Sky Harbor Intl to Santa Barbara flights
Las Vegas to Long Beach flights
Las Vegas to Santa Rosa flights
Sky Harbor Intl to Medford flights
Las Vegas to Palm Springs flights
Tucson to Reno flights
Sky Harbor Intl to Santa Rosa flights
Tucson to Sacramento flights
Las Vegas to San Luis Obispo flights
Sky Harbor Intl to Bakersfield flights
Tucson to Burbank flights
Tucson to San Jose flights
Las Vegas to Monterey flights
Tucson to Palm Springs flights
Sky Harbor Intl to Redding flights

Top 7 airlines flying from Mesa to San Diego

Discover the top 7 airlines that operate flights from Mesa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$47Average$127FlexibilityNo cancel feeOn-time65%
FrontierCheapest$56Average$148FlexibilityNo cancel feeOn-time62%
Hawaiian AirlinesCheapest$58Average$147FlexibilityNo cancel feeOn-time85%
Alaska AirlinesCheapest$79Average$146FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$93Average$207FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$97Average$237FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$269Average$408FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.