$29+ Cheap flights from Mesa, AZ to San Diego (SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SAN
Mar 6 — Mar 131
1 adult, Economy
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Find cheap flights from Mesa to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to San Diego are usually found in October or September, booked 80 days in advance, depart on a Friday or Thursday and return on a Friday
Cheap flight deals from Mesa to San Diego
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Best
Last-minute
One-way
Cheapest flights from Mesa to San DiegoExplore the most affordable flight options available from Mesa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
Explore the most affordable flight options available from Mesa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:09 pm
PHX
- SAN
Nonstop1h 16m
Frontier
Sun 5/103:20 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 2/2![Frontier logo]()
$60
This Super.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/168:04 pm
PHX
- SAN
Nonstop1h 24m
Frontier
Thu 3/199:44 pm
SAN
- PHX
Nonstop1h 28m
Frontier
Deal found 2/1![Frontier logo]()
$65
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:59 pm
PHX
- SAN
Nonstop1h 20m
Frontier
Sun 3/18:20 pm
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 2/3![Frontier logo]()
$67
This Super.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/111:09 pm
PHX
- SAN
Nonstop1h 22m
Frontier
Sat 3/143:16 pm
SAN
- PHX
Nonstop1h 25m
Frontier
Deal found 2/1![Frontier logo]()
$71
This Frontier deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:59 pm
PHX
- SAN
Nonstop1h 20m
Frontier
Fri 2/278:20 pm
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 2/1![Frontier logo]()
$72
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:59 pm
PHX
- SAN
Nonstop1h 20m
Frontier
Sun 2/228:10 pm
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 2/3![Frontier logo]()
$73
This Trip.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/202:08 pm
PHX
- SAN
Nonstop1h 21m
Frontier
Fri 3/274:15 pm
SAN
- PHX
Nonstop1h 27m
Frontier
Deal found 2/3![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:09 pm
PHX
- SAN
Nonstop1h 16m
Frontier
Sat 5/163:20 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 1/31![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:51 pm
PHX
- SAN
1 stop10h 33m
Frontier
Sat 3/73:16 pm
SAN
- PHX
Nonstop1h 25m
Frontier
Deal found 1/31![Frontier logo]()
$77
This Frontier deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/125:26 pm
PHX
- SAN
Nonstop1h 25m
Frontier
Sun 2/158:10 pm
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 2/2![Frontier logo]()
$78
This eDestinos deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2212:24 pm
PHX
- SAN
Nonstop1h 23m
Frontier
Sun 2/228:10 pm
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 2/1![Frontier logo]()
$80
Best flights from Mesa to San DiegoDiscover carefully curated flight deals from Mesa to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
Discover carefully curated flight deals from Mesa to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
This CheapOair deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:20 am
PHX
- SAN
Nonstop1h 18m
Alaska Airlines
Sun 3/19:21 pm
SAN
- PHX
Nonstop1h 21m
Alaska Airlines
Deal found 2/1![Alaska Airlines logo]()
$117
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/69:20 pm
PHX
- SAN
Nonstop1h 15m
Southwest
Sun 3/86:40 am
SAN
- PHX
Nonstop1h 30m
Southwest
Deal found 2/1![Southwest logo]()
$117
This Frontier deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:25 am
PHX
- SAN
1 stop7h 18m
Frontier
Sat 2/2812:23 pm
SAN
- PHX
1 stop10h 36m
Frontier
Deal found 2/2![Frontier logo]()
$138
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:50 pm
PHX
- SAN
1 stop3h 24m
Delta
Tue 3/103:45 pm
SAN
- PHX
1 stop6h 25m
Delta
Deal found 2/2![Delta logo]()
$159
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:19 pm
PHX
- SAN
1 stop4h 40m
United Airlines
Tue 4/76:22 pm
SAN
- PHX
1 stop5h 37m
United Airlines
Deal found 2/1![United Airlines logo]()
$159
This Alaska Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/44:27 pm
PHX
- SAN
Nonstop1h 17m
Alaska Airlines
Wed 3/49:21 pm
SAN
- PHX
Nonstop1h 21m
Alaska Airlines
Deal found 1/31![Alaska Airlines logo]()
$117
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:45 pm
PHX
- SAN
2 stops5h 10m
Southwest
Wed 4/294:25 pm
SAN
- PHX
Nonstop1h 25m
Southwest
Deal found 1/31![Southwest logo]()
$132
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/71:40 pm
PHX
- SAN
1 stop4h 10m
Southwest
Wed 4/88:35 am
SAN
- PHX
1 stop4h 35m
Southwest
Deal found 2/1![Southwest logo]()
$137
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:30 pm
PHX
- SAN
1 stop5h 16m
Delta
Mon 4/277:55 pm
SAN
- PHX
1 stop3h 19m
Delta
Deal found 2/2![Delta logo]()
$159
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
PHX
- SAN
1 stop4h 20m
United Airlines
Mon 4/66:20 am
SAN
- PHX
1 stop3h 34m
United Airlines
Deal found 2/2![United Airlines logo]()
$159
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:50 pm
PHX
- SAN
1 stop3h 24m
Delta
Wed 3/113:45 pm
SAN
- PHX
1 stop3h 25m
Delta
Deal found 2/2![Delta logo]()
$159
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:10 am
PHX
- SAN
Nonstop1h 20m
Southwest
Wed 3/256:35 pm
SAN
- PHX
1 stop4h 30m
Southwest
Deal found 2/2![Southwest logo]()
$157
Last-minute flights from Mesa to San DiegoDiscover last-minute flight deals from Mesa to San Diego. Data last updated February 4, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to San Diego. Data last updated February 4, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/125:26 pm
PHX
- SAN
Nonstop1h 25m
Frontier
Sun 2/158:10 pm
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 2/2![Frontier logo]()
$78
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:59 pm
PHX
- SAN
Nonstop1h 20m
Frontier
Sun 2/228:10 pm
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 2/3![Frontier logo]()
$73
This eDestinos deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2212:24 pm
PHX
- SAN
Nonstop1h 23m
Frontier
Sun 2/228:10 pm
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 2/1![Frontier logo]()
$80
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:59 pm
PHX
- SAN
Nonstop1h 20m
Frontier
Sun 3/18:20 pm
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 2/3![Frontier logo]()
$67
This Frontier deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:26 pm
PHX
- SAN
Nonstop1h 25m
Frontier
Sat 2/288:00 am
SAN
- PHX
Nonstop1h 30m
Frontier
Deal found 2/2![Frontier logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:51 pm
PHX
- SAN
1 stop10h 33m
Frontier
Sat 3/73:16 pm
SAN
- PHX
Nonstop1h 25m
Frontier
Deal found 1/31![Frontier logo]()
$77
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:20 pm
PHX
- SAN
Nonstop1h 22m
Multiple Airlines
Wed 3/113:16 pm
SAN
- PHX
Nonstop1h 25m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$82
This Super.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:49 pm
PHX
- SAN
Nonstop1h 22m
Frontier
Mon 3/94:29 pm
SAN
- PHX
Nonstop1h 27m
Frontier
Deal found 2/3![Frontier logo]()
$81
This Super.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/111:09 pm
PHX
- SAN
Nonstop1h 22m
Frontier
Sat 3/143:16 pm
SAN
- PHX
Nonstop1h 25m
Frontier
Deal found 2/1![Frontier logo]()
$71
This Super.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/168:04 pm
PHX
- SAN
Nonstop1h 24m
Frontier
Thu 3/199:44 pm
SAN
- PHX
Nonstop1h 28m
Frontier
Deal found 2/1![Frontier logo]()
$65
This Trip.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/202:08 pm
PHX
- SAN
Nonstop1h 21m
Frontier
Fri 3/274:15 pm
SAN
- PHX
Nonstop1h 27m
Frontier
Deal found 2/3![Frontier logo]()
$74
One-way flights from Mesa to San DiegoSearch for one-way flight options from Mesa to San Diego. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
Search for one-way flight options from Mesa to San Diego. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
This Frontier deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/129:59 pm
PHX
- SAN
Nonstop1h 20m
Frontier
Deal found 2/2![Frontier logo]()
$29
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:09 pm
PHX
- SAN
Nonstop1h 16m
Frontier
Deal found 2/3![Frontier logo]()
$31
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/178:00 pm
PHX
- SAN
Nonstop1h 24m
Frontier
Deal found 2/3![Frontier logo]()
$38
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/191:09 pm
PHX
- SAN
Nonstop1h 16m
Frontier
Deal found 2/2![Frontier logo]()
$41
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:09 pm
PHX
- SAN
Nonstop1h 16m
Frontier
Deal found 2/3![Frontier logo]()
$43
This Super.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/141:09 pm
PHX
- SAN
Nonstop1h 22m
Frontier
Deal found 2/2![Frontier logo]()
$49
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:20 pm
PHX
- SAN
Nonstop1h 15m
Southwest
Deal found 2/1![Southwest logo]()
$50
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:00 am
PHX
- SAN
1 stop6h 28m
Frontier
Deal found 2/1![Frontier logo]()
$53
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:54 pm
PHX
- SAN
1 stop7h 10m
Frontier
Deal found 2/3![Frontier logo]()
$56
This Super.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:49 pm
PHX
- SAN
Nonstop1h 22m
Frontier
Deal found 2/3![Frontier logo]()
$58
This Alaska Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:20 pm
PHX
- SAN
Nonstop1h 22m
Alaska Airlines
Deal found 2/2![Alaska Airlines logo]()
$59
Find flight deals from Mesa to San Diego
Keep the following information in mind while searching for Mesa to San Diego flight deals. Data was last updated February 4, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $65 (Kiwi.com) |
One-way from | $29 (Frontier) |
Popular in | January |
Cheapest in | October |
Average price | $115 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Mesa to San Diego that are best for you.
Fly from
Mesa
Fly to
San Diego
Route
Depart
Return
Price
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Wed 2/25
8:20 am-8:38 am
Nonstop1h 18m
San Diego
Sun 3/1
9:21 pm-11:42 pm
Nonstop1h 21m
$117
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Fri 3/6
9:20 pm-9:35 pm
Nonstop1h 15m
San Diego
Sun 3/8
6:40 am-8:10 am
Nonstop1h 30m
$117
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Wed 3/4
4:27 pm-4:44 pm
Nonstop1h 17m
San Diego
Wed 3/4
9:21 pm-11:42 pm
Nonstop1h 21m
$117
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Tue 4/28
12:45 pm-5:55 pm
2 stops5h 10m
San Diego
Wed 4/29
4:25 pm-5:50 pm
Nonstop1h 25m
$132
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Tue 4/7
1:40 pm-5:50 pm
1 stop4h 10m
San Diego
Wed 4/8
8:35 am-1:10 pm
1 stop4h 35m
$137
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Thu 2/26
7:25 am-1:43 pm
1 stop7h 18m
San Diego
Sat 2/28
12:23 pm-11:59 pm
1 stop10h 36m
$138
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Sat 3/21
6:10 am-7:30 am
Nonstop1h 20m
San Diego
Wed 3/25
6:35 pm-11:05 pm
1 stop4h 30m
$157
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Mon 3/9
7:50 pm-11:14 pm
1 stop3h 24m
San Diego
Tue 3/10
3:45 pm-10:10 pm
1 stop6h 25m
$159
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Fri 4/3
7:19 pm-11:59 pm
1 stop4h 40m
San Diego
Tue 4/7
6:22 pm-11:59 pm
1 stop5h 37m
$159
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Sat 4/25
5:30 pm-10:46 pm
1 stop5h 16m
San Diego
Mon 4/27
7:55 pm-11:14 pm
1 stop3h 19m
$159
Showing 1-10 of 23 results
Best time to book a flight from Mesa to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Mesa with our price prediction graph.
PHX-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to San Diego
MS9-SAN
PHX-SAN
How far ahead should I book a flight from Mesa to San Diego?
Use this chart to determine the optimal time to book a round-trip flight from Mesa to San Diego. Price data was last updated on January 30, 2026.
Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Mesa to San Diego?
Currently, February is the cheapest month in which you can book a flight from Mesa to San Diego (average of $38). Flying from Mesa to San Diego in June is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MS9 to SAN?
Find hourly flight availability from Mesa to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 4, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 32% on flights from Mesa to San Diego by exploring options for tickets in the afternoon.
What is the cheapest day to fly from Mesa to San Diego?
Use this chart to determine the cheapest time to fly round-trip from Mesa to San Diego. Price data was last updated on January 31, 2026.
Travelers seeking maximum savings on their Mesa to San Diego flight should consider departing on Friday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Mesa to San Diego
Explore weekly flight availability from Mesa to San Diego. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 4, 2026.
The most flights from MS9 to SAN are scheduled on a Monday (24 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (8 on average).
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated February 4, 2026.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest, and Hawaiian Airlines from Mesa to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
8.0
Food
7.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
8.0
Food
7.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
8.0
Food
7.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
8.0
Food
7.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
8.0
Food
7.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Entertainment
7.0
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
8.0
Food
7.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Jan 2026
STS - LAX
Related info for your journey
Find useful and relevant information for your journey from Mesa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove
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Alternative routes for Mesa to San Diego
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Complete your trip
Complete your trip to San Diego by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mesa to San Diego by cabin class
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Mesa and San Diego flights
Browse other Mesa and San Diego flight options. Last updated on February 4, 2026.
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Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 4, 2026.
Mesa to San Diego flights
Consider these flights traveling from Mesa to San Diego.
Top 7 airlines flying from Mesa to San Diego
Discover the top 7 airlines that operate flights from Mesa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$41 | Average$148 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$47 | Average$110 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$48 | Average$137 | FlexibilityNo cancel fee | On-time85% | |
| Cheapest$79 | Average$151 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$93 | Average$196 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$97 | Average$234 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$273 | Average$408 | FlexibilityNo cancel fee | On-time69% |